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International Journal of Ophthalmology(English edition) 2014年第4期7卷 697-703页

作者： Lukas Reznicek Carmen Stumpf florian seidensticker Anselm Kampik Aljoscha S Neubauer Marcus Kernt Department of Ophthalmology Ludwig Maximilians University Muenchen

·AIM:Toevaluatethe diagnostic properties of wide-field fundus autofluorescence(FAF) scanning laser ophthalmoscope(SLO) imaging for differentiating choroidal pigmented lesions.·METHODS: A consecutive series of 139 patients were included, 101 had established choroidal melanoma with13 untreated lesions and 98 treated with ***-eight had choroidal nevi. All patients underwent a full ophthalmological examination, undilated wide-field imaging, FAF and standardized US examination. FAF images and imaging characteristics from SLO were correlated with the structural findings in the two patient groups.·RESULTS: Mean FAF intensity of melanomas was significantly lower than the FAF of choroidal nevi. Only 1out of 38 included eyes with nevi touched the optic disc compared to 31 out of 101 eyes with melanomas. In 18 out of 101 melanomas subretinal fluid was seen at the pigmented lesion compared to none seen in eyes with confirmed choroidal nevi. In 'green laser separation', a trend towards more mixed FAF appearance of melanomas compared to nevi was observed. The mean maximal and minimal transverse and longitudinal diameters of melanomas were significantly higher than those of nevi.·CONCLUSION: Wide-field SLO and FAF imaging may be an appropriate non-invasive diagnostic screening tool to differentiate benign from malign pigmented choroidal lesions.

关键词： imaging autofluorescence scanning laser ophthalmoscopy choroidal lesion melanoma

Peripheral retinal non-perfusion and treatment response in branch retinal vein occlusion

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International Journal of Ophthalmology(English edition) 2016年第6期9卷 858-862页

作者： Kaveh Abri Aghdam Lukas Reznicek Mostafa Soltan Sanjari Carsten Framme Anna Bajor Annemarie Klingenstein Marcus Kernt florian seidensticker Department of Ophthalmology University Eye HospitalMedical School of Hannover Carl-Neuberg-Straβe 1Hannover 30625 Germany Department of Ophthalmology Ludwig Maximilians University Mathildenstr. 8 Munich 80336 Germany Eye Research Center Rassoul Akram Hospital lranUniversity of Medical Sciences Sattarkhan-Niayesh StreetTehran 14456-13131 Iran

AIM： To evaluate the association between the size of peripheral retinal non-perfusion and the number of intravitreal ranibizumab injections in patients with treatment-naive branch retinal vein occlusion （BRVO） and macular edema. METHODS： A total of 53 patients with treatment-naive BRVO and macular edema were included. Each patient underwent a full ophthalmologic examination including optical coherence tomography （OCT） imaging and ultra wide-field fluorescein angiography （UWFA）. Monthly intravitreal ranibizumab injections were applied according to the recommendations of the German Ophthalmological Society. Two independent, masked graders quantified the areas of peripheral retinal non-perfusion. RESULTS： Intravitreal injections improved bestcorrected visual acuity （BCVA） significantly from 22.23± 16.33 Early Treatment of Diabetic Retinopathy Study （ETDRS） letters to 36.23 ±15.19 letters （P〈0.001）, and mean central subfield thickness significantly reduced from 387±115 pm to 321±115 μm （P=0.01）. Mean number of intravitreal ranibizumab injections was 3.61±1.56. The size of retinal non-perfusion correlated significantly with the number of intravitreal ranibizumab injections （R= 0.724, P〈0.001）. CONCLUSION： Peripheral retinal non-perfusion in patients with BRVO associates significantly with intravitreal ranibizumab injections in patients with BRVO and macular edema.

关键词： angiography branch retinal vein occlusion non-perfusion retina wide-field

Saving wild tigers:A case study in biodiversity loss and challenges to be met for recovery beyond 2010

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Integrative Zoology 2010年第4期5卷 285-299页

作者： John seidensticker Smithsonian Conservation Biology Institute National Zoological ParkWashingtonDCUSA

Wild tigers are being *** range countries and their partners met at the 1st Asian Ministerial Conference on Tiger Conservation in January 2010 to mandate the creation of the Global Tiger Recovery Program to double the number of tigers by *** 3200-3600 wild adult tigers remain,approximately half of the population estimated a decade *** now live in only 13 countries,all of which are experiencing severe environmental challenges and degradation from the effects of human population growth,brisk economic expansion,rapid urbanization,massive infrastructure development and climate *** overarching challenge of tiger conservation,and the conservation of biodiversity generally,is that there is insufficient demand for the survival of wild tigers living in natural *** allows the criminal activities of poaching wild tigers and their prey and trafficking in tiger derivatives to flourish and tiger landscapes to be *** Global Tiger Recovery Program will support scaling up of practices already proven effective in one or more tiger range countries that need wider policy support,usually resources,and new transnational actions that enhance the effectiveness of individual country *** program is built on robust National Tiger Recovery Priorities that are grouped into themes:(i)strengthening policies that protect tigers;(ii)protecting tiger conservation landscapes;(iii)scientific management and monitoring;(iv)engaging communities;(v)cooperative management of international tiger landscapes;(vi)eliminating transnational illegal wildlife trade;(vii)persuading people to stop consuming tiger;(viii)enhancing professional capacity of policy-makers and practitioners;and(ix)developing sustainable,long-term financing mechanisms for tiger and biodiversity conservation.

关键词： Asia biodiversity Global Tiger Recovery Program Panthera tigris Tiger Conservation Landscape

Radioembolization for neuroendocrine liver metastases is safe and effective prior to major hepatic resection

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Hepatobiliary Surgery and Nutrition 2020年第3期9卷 312-321页

作者： florian Bosch Harun Ilhan Vanessa Pfahler Michael Thomas Thomas Knosel Valentin Eibl Sebastian Pratschke Peter Bartenstein Max seidensticker Christoph J.Auernhammer Christine Spitzweg Markus O.Guba Jens Werner Martin K.Angele Department of General Visceraland Transplant SurgeryLudwig-Maximilians-University MunichMunichGermany Interdisciplinary Center of Neuroendocrine Tumors of the Gastro Entero Pancreatic System Ludwig-Maximilians-University MunichMunichGermany Department of Nuclear Medicine University HospitalLudwig-Maximilians-University MunichMunichGermany Department of Radiology Ludwig-Maximilians-University MunichMunichGermany Institute of Pathology Ludwig-Maximilians-University MunichMunichGermany Department of Internal Medicine 4 Ludwig-Maximilians-University MunichMunichGermany

Background:Radioembolization(RE)is well established in the treatment of neuroendocrine liver *** surgery is rarely performed after RE,although liver resection is the gold standard in the treatment of localized neuroendocrine liver ***,aim of the present study was to evaluate the safety and feasibility of liver resection after RE in a homogenous ***:From a prospective surgical(n=494)and nuclear medical(n=138)database patients with NELM who underwent liver resection and/or RE were *** September 2011 and December 2017 eight patients could be identified who underwent liver resection after RE(mean therapeutic activity of 1,746 Mbq).Overall and progression free survival were evaluated as well as epidemiological and perioperative *** surgical specimens were analyzed for necrosis,fibrosis,inflammation,and ***:The mean hepatic tumor load of patients,who had liver surgery after RE,was 31.4%with a mean Ki-67 proliferation index of 5.9%.The majority of these patients(7/8)received whole liver RE prior to liver resection,which did not increase morbidity and mortality compared to a surgical *** for RE were oncological(6/8)or carcinoid syndrome associated reasons(2/8).Mean overall survival was 25.1 months after RE and subsequent *** necrosis in radioembolized lesions was 29.4%without evidence of fibrosis and inflammation in hepatic ***:This is the first study analyzing the multimodal therapeutic approach of liver resection following whole liver *** treatment algorithm is safe,does not lead to an increased morbidity and is associated with a favorable oncological ***,patient selection remains a key issue.

关键词： Radioembolization(RE) neuroendocrine tumor liver surgery

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美国口语词典

作者：张文华编译

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美国口语词典

心脏CT双期对比剂注射:相同碘流量和碘剂量的中和高浓度对比剂的对比

1990年

作者：（美）赛登施蒂克（seidensticker Edward G.）（美）麦凯莱布（McCaleb John G.）（日）安田一郎编张文华编译

编者原题无汉译名:本书收录了当代美国人日常会话中最新和最常用的语句、句型4000条,例句2万个。

ISBN: (数字)7560008097

编者原题无汉译名:本书收录了当代美国人日常会话中最新和最常用的语句、句型4000条,例句2万个。

关键词：英语-口语(地点: 美国学科: 词典) 口语-英语(地点: 美国学科: 词典)

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国际医学放射学杂志 2010年第5期 505-505页

作者： A.Rutten M.F.L.Meijs A.M.de Vos P.R.seidensticker M.Prokop 卞读军 Department of Radiology University Medical Center UtrechtUtrechtThe Netherlands

关键词： CT 冠状动脉CT血管成像对比剂浓度对比剂注射方式

多层CT评估心肌活力:兔模型中单体与双体对比剂的个体内比较

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国际医学放射学杂志 2009年第2期32卷 201-201页

作者： A.H.Mahnken G.Jost P.Bruners M.Sieber P.R.seidensticker R.W. Günther 刘靖 Department of Diagnostic Radiology University HospitalRWTH Aachen University

为研究不同碘离子对比剂对心肌活力评估的影响，在6只兔上用外科手术建立了急性心肌梗死模型。45min内，以600mgI／kg体质量的对比剂重复进行心脏多层CT增强检查（64×0．6mm，80kV，680mAs）。动物随机应用碘普罗胺300和碘克沙醇320。... 详细信息

为研究不同碘离子对比剂对心肌活力评估的影响，在6只兔上用外科手术建立了急性心肌梗死模型。45min内，以600mgI／kg体质量的对比剂重复进行心脏多层CT增强检查（64×0．6mm，80kV，680mAs）。动物随机应用碘普罗胺300和碘克沙醇320。测量健康及梗死心肌的衰减值。计算心肌梗死大小，并与四唑硝基兰（nitroblue tetrazolium，NBT）染色的标本比较。

关键词： CT 多层CT 对比剂心脏心肌梗死