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Percutaneous assist devices in acute myocardial infarction with cardiogenic shock: Review, meta-analysis

World Journal of Cardiology 2016年第1期8卷 98-111页

作者： Francesco Romeo Maria Cristina Acconcia Domenico Sergi Alessia Romeo Simona Francioni flavia Chiarotti Quintilio Caretta Department of Cardiovascular Disease University of Rome-Tor Vergata Department of Cardiovascular Disease University of Rome-La Sapienza Center for Biomedical Technology and Integrated Department Services to Education University of Florence Department of Cell Biology and Neuroscience Italian National Institute of Health Department of Experimental and Clinical Medicine University of Florence

AIM: To assess the impact of percutaneous cardiac support in cardiogenic shock(CS) complicating acute myocardial infarction(AMI), treated with percutaneous coronary intervention. METHODS: We selected all of the studies published from January 1st, 1997 to May 15 st, 2015 that compared the following percutaneous mechanical support in patients with CS due to AMI undergoing myocardial revascularization:(1) intra-aortic balloon pump(IABP) vs Medical therapy;(2) percutaneous left ventricular assist devices(PLVADs) vs IABP;(3) complete extracorporeal life support with extracorporeal membrane oxygenation(ECMO) plus IABP vs IABP alone; and(4) ECMO plus IABP vs ECMO alone, in patients with AMI and CS undergoing myocardial revascularization. We evaluated the impact of the support devices on primary and secondary endpoints. Primary endpoint was the inhospital mortality due to any cause during the same hospital stay and secondary endpoint late mortality at 6-12 moof follow-up. RESULTS: One thousand two hundred and seventytwo studies met the initial screening criteria. After detailed review, only 30 were selected. There were 6 eligible randomized controlled trials and 24 eligible observational studies totaling 15799 patients. We found that the inhospital mortality was:(1) significantly higher with IABP support vs medical therapy(RR = +15%, P = 0.0002);(2) was higher, although not significantly, with PLVADs compared to IABP(RR = +14%, P = 0.21); and(3) significantly lower in patients treated with ECMO plus IABP vs IABP(RR =-44%, P = 0.0008) or ECMO(RR =-20%, P = 0.006) alone. In addition, Trial Sequential Analysis showed that in the comparison of IABP vs medical therapy, the sample size was adequate to demonstrate a significant increase in risk due to IABP. CONCLUSION: Inhospital mortality was significantly higher with IABP vs medical therapy. PLVADs did not reduce early mortality. ECMO plus IABP significantly reduced inhospital mortality compared to IABP.

关键词： Intra-aortic balloon pump Impella Tandem Heart Extracorporeal membrane oxygenation Cardiogenic shock Meta-analysis

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Strategies for the analysis of single-tree plot experiments in Eucalyptus plantations

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Journal of Forestry Research 2021年第6期32卷 2437-2445页

作者： Heloisa Guimaraes Santos flavia Maria Avelar Goncalves Jose Luis Lima Aurelio Mendes Aguiar Gabriel Dehon Sampaio Pecanha Rezende Bruno Marco de Lima Magno Antonio Patto Ramalho Departamento de Biologia Setor de Genetica E Melhoramento de PlantasUniversidade Federal de Lavras-UFLALavrasMGBrasil Suzano Papel E Celulose Sao PauloSPBrasil Bracell SP Celulose Ltda Lencóis PaulistaSPBrasil

To verify if the response by Eucalyptus clones in a single-tree plot is influenced by neighboring plants and to determine the effect of missing and/or dominated plants,seven eucalyptus trials in four Brazilian states were analyzed in a randomized complete block design with one plant/plot and 30 *** annual increment(MAI,m^(3)ha^(-1)per year)was determined for three-year-old *** influence of neighboring clones was estimated by a linear regression coefficient between the MAI of each clone/plot and the average of a clonal MAI and its eight *** determine the effect of missing and/or dominated trees,a correction between the MAI and the area available/plant was *** analysis considered unadjusted and adjusted data for missing and dominated *** of accuracy and index of coincidence were used to compare the *** single-tree plots,clone performances were not influenced by neighboring *** accuracy was not increased by any of the adjustments employed and the clone ranking was not altered,and therefore did not justify their use.

关键词： Single-tree plot Missing plant adjustment Eucalyptus breeding

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Acupuncture for breakthrough pain in cancer:A medical record

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World Journal of Acupuncture-Moxibustion 2021年第4期31卷 254-257页

作者： Diana Lalli flavia Santoboni Riccardo Vallorani Mario Vetrano Eleonora Latini Sveva Maria Nusca Maria Chiara Vulpiani Department of Surgical and Medical Sciences and Translational Medicine Faculty of Medicine and Psychology"Sapienza"University of Romevia di Grottarossa 1035-1039Rome 00189Italy Physical Medicine and Rehabilitation Unit Sant'Andrea University HospitalVia di Grottarossa 1035-1039Rome 00189Italy

Patients with chronic cancer pain frequently suffer from severe pain intensity exacerbations.A 60-years old woman had been experiencing Breakthrough Cancer Pain(BTCP) mostly concentrated on shoulders since the resection of the upper right lung lobe one year before,reason why she underwent Traditional Chinese Medicine treatment(TCM).She was diagnosed with *** strong opioids intake during radiotherapy and chemotherapy,she continued to suffer from pain without benefiting from these *** was treated with somatic and auricular acupuncture and cupping technique for 10 sessions,2-3 sessions per week,30 min per *** five/six sessions of treatment the patient felt much better,relieved from the pain with an improving Numeric rating Scale(NRS) and an important improving of Breakthrough Pain Assessment Tool-BAT and Constant-Murley *** cancer patients,acupuncture could represent an effective treatment option.

关键词： Acupuncture Breakthrough pain Cancer Case report

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意大利艺术博物馆重开大数据派上用场

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商业周刊（中文版） 2021年第13期 16-17页

作者： flavia Rotondi 王忠(译) 不详

正当意大利的博物馆和画廊重新迎来宾客上门,并试图弥补2020年约1.9亿欧元(约合14.61亿元)的收入损失之际,一个新的数据分析项目可以帮助策展者了解哪些画作和雕塑最能吸引观众。

关键词：艺术博物馆大数据数据分析收入损失吸引观众策展者意大利

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新千年的科技警探

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Newton-科学世界 2003年第6期 72-77页

作者： flavia Caroppo 王宝泉

光导纤维夜视仪、防盗手枪、枪手测量棉、电子耳朵、电子鼻和机器人警察……科技为警察提供了越来越高明的对付犯罪的武器和装备。魔高一尺，道高一丈，罪犯终究难逃恢恢法网。

关键词：光导纤维夜视仪防盗手枪枪手测量棉警察武器装备

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Organic Coffee under Perspective of Energy Efficiency

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Journal of Agricultural Science and Technology(B) 2014年第1期4卷 15-20页

作者： Patricia Helena Nogueira Turco Osmar de Carvalho Bueno: Maura Seiko Tsutsui Esperancini flavia Mariade Mello Bliska Department of Decentralization of Development Agriculture Secretary of S6o Paulo State Sao Paulo Agency of AgribusinessTechnology Campinas 13012-970 Sao Paulo Brazil Department of Economics and Rural Sociology Faculty of Agricultural Sciences of Botucatu Universidade Jfilio de MesquitaFilho Paulista State University Rua Josd Barbosa de Barros Botucatu 18603-970 Sao Paulo Brazil Agriculture Secretary of Sao Paulo State Sao Paulo Agency of Agribusiness Technology Coffee Centre Agronomic InstituteCampinas 13012-970 Sao Paulo Brazil

The energy analysis development in this study contributes to the understanding of the dynamics of the organic coffee productive system, in particular to assess the independence of this system with respect to the use of industrialized input products. Thus, it provides information about the sustainability of that production system. Technical itineraries used in this study consist of energy expenditure made with coffee cultivation, according to the type, source and form of energy inputs, agricultural machines, equipment and labor force used in that production system. The energy expenditure, converted into energy units, quantified the input energy. And the organic coffee production, measured in kilograms of processed coffee beans, was the output energy. Primary data used in this study were obtained from organic coffee producers in the Southern region of Minas Gerais State, Brazil, in 2011. Energy balance identified was positive, since the estimated output energy was 626.465 M J/ha and the energy expenditure was 112.998 M J/ha, during the useful life of the crop.

关键词： Energetic balance sustainable production coffee cultivation.

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如何对待内心的小恶魔

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芳草（经典阅读） 2014年第10期 47-48页

作者： flavia Mazelin Salvi 张璐

有时候，面对过失我们会隐瞒，面对事实我们会狡辩，面对朋友我们会撒谎……我们每个人都在不同程度上有过“邪恶”，这些恶念绝不是评判我们道德的标准。心理学家认为，这多多少少是有意识的自我保护策略。

关键词：恶魔内心心理学家保护策略有意识

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宠物教给我们些什么

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跨世纪(时文博览) 2007年第4期 16-17页

作者： flavia Mazelin Salvi 汪汪

宠物是驱逐孤独感和紧张情绪的良药,也是真正的人生课堂上的老师。前提是我们要仔细地观察它们和爱它们。

关键词：宠物玩畜

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COVID-19 in dialysis units: A comprehensive review

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World Journal of Virology 2021年第5期10卷 264-274页

作者： Gabriel Martins Nogueira Moises Santana Oliveira Ana flavia Moura Constanca Margarida Sampaio Cruz JoseA Moura-Neto Department of Medicine Bahiana School of Medicine and Public HealthSalvador 40290-000Brazil Department of Internal Medicine Bahiana School of Medicine and Public HealthSalvador 40290-000Brazil Department of Internal Medicine Hospital Santo AntônioSalvador 40415-006Brazil

The coronavirus disease 2019(COVID-19)pandemic has been challenging for healthcare professionals *** of the populations affected by the pandemic are patients on renal replacement therapy,as kidney disease is an independent risk factor for severe COVID-19 and maintenance dialysis(a lifesustaining therapy)cannot be interrupted in the vast majority of *** the past months,several authors and medical societies have published recommendations and guidelines on the management of this *** article is a comprehensive review regarding the measures to prevent,contain and deal with a COVID-19 pandemic in the dialysis *** recapitulate the epidemiology and pathophysiology of COVID-19 in kidney dysfunction and present the main recommendations concerning the screening of healthcare personnel,dialysis patients and visitors as well as measures to improve the safety of the dialysis facilities’*** addition to preventive measures,this article briefly describes actions directed towards management of an outbreak of the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)within a dialysis facility,the management of complications in dialysis patients with COVID-19 and overall data regarding the management of children with kidney disease.

关键词： COVID-19 SARS-CoV-2 Renal dialysis Renal replacement therapy Hemodialysis units,Hospital

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Small interfering RNA for cancer treatment:overcoming hurdles in delivery

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Acta Pharmaceutica Sinica B 2020年第11期10卷 2075-2109页

作者： Nitin Bharat Charbe Nikhil D.Amnerkar B.Ramesh Murtaza M.Tambuwala Hamid A.Bakshi Alaa A.A.Aljabali Saurabh C.Khadse Rajendran Satheeshkumar Saurabh Satija Meenu Metha Dinesh Kumar Chellappan Garima Shrivastava Gaurav Gupta Poonam Negi Kamal Dua flavia C.Zacconin Departamento de Quimica Orgánica Facultad de Química y de FarmaciaPontificia Universidad Católica de ChileSantiago 7820436Chile Sri Adichunchunagiri College of Pharmacy Sri Adichunchunagiri UniversityBG NagarKarnataka 571418India Adv V.R.Manohar Institute of Diploma in Pharmacy NagpurMaharashtra 441110India School of Pharmacy and Pharmaceutical Science Ulster UniversityColeraineNorthern Ireland BT521SAUK Faculty of Pharmacy Department of Pharmaceutics and Pharmaceutical TechnologyYarmouk UniversityIrbid 21163Jordan Department of Pharmaceutical Chemistry R.C.Patel Institute of Pharmaceutical Education and ResearchDist.DhuleMaharashtra 425405India Discipline of Pharmacy Graduate School of HealthUniversity of Technology SydneyNSW 2007Australia School of Pharmaceutical Sciences Lovely Professional UniversityPhagwara 144411 PunjabIndia Department of Life Sciences School of PharmacyInternational Medical UniversityBukit Jalil 57000Kuala LumpurMalaysia Department of Biochemical Engineering and Biotechnology Indian Institute of TechnologyDelhiNew Delhi 110016India School of Pharmacy Suresh Gyan Vihar UniversityJagatpuraJaipur 302017India School of Pharmaceutical Sciences Shoolini University of Biotechnology and Management SciencesSolan 173229India Priority Research Centre for Healthy Lungs Hunter Medical Research Institute(HMRI)and School of Biomedical Sciences and PharmacyUniversity of NewcastleNSW 2308Australia Institute for Biological and Medical Engineering Schools of EngineeringMedicine and Biological SciencesPontificia Universidad Católica de ChileSantiago 4860Chile

In many ways,cancer cells are different from healthy cells.A lot of tactical nano-based drug delivery systems are based on the difference between cancer and healthy ***,nanotechnology-based delivery systems are the most promising tool to deliver DNA-based products to cancer *** review aims to highlight the latest development in the lipids and polymeric nanocarrier for siRNA delivery to the cancer *** also provides the necessary information about siRNA development and its mechanism of ***,this review gives us a clear picture of lipid and polymer-based drug delivery systems,which in the future could form the base to translate the basic siRNA biology into siRNA-based cancer therapies.

关键词： Small interfering RNA(siRNA) Nanomedicine Liposomes Micelles Cancer Polymer

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