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Prevalence and Determ.nants of Kidney m.rkers am.ng Subjects with Hepatitis C Virus Infection

Open Journal of Nephrology 2020年第2期10卷 85-101页

作者： m.thurin Pierre Kowo Sylvain Raoul Sim.ni Njonnou m.rielle Sonia m.hly Ngninzeko firmin Ankouane Andoulo Antonin Ndjitoyap Ndam.m.chelle Tagny Sartre Vicky Am. m.or Jeanne Ngongang François Folefack Kaze Departm.nt of Internal m.dicine and Specialty Faculty of Medicine and Biomedical Sciences University of Yaoundé I Yaoundé Cameroon Yaounde University Teaching Hospital Yaoundé Cameroon Departm.nt of Internal m.dicine and Specialty Faculty of Medicine and Pharmaceutical Sciences University of Dschang Dschang Cameroon Higher Institute of Health Sciences Université des Montagnes Bangangté Cameroon m.dical Centre “La Cathédrale” Yaoundé Cameroon Departm.nt of Physiological Sciences and Biochem.stry Faculty of Medicine and Biomedical Sciences University of Yaoundé I Yaoundé Cameroon

Introduction: Hepatitis C virus (HCV) infection is a worldwide public health problem.with m.ltisystem.c involvem.nts including kidneys. We assessed the prevalence and determ.nants of kidney m.rkers am.ng HCV infected subjects. m.thods: A cross-sectional study was conducted from.m.rch to July 2017 in two referral centers in Yaoundé. Sociodem.graphic, clinical and paraclinical data were collected from.patient’s records. Renal involvem.nt was evaluated using estim.ted glom.rular filtration rate (eGFR) by m.dification of Diet in Renal Disease’s (m.RD) equation, urine dipstick and album.n/creatinine ratio (ACR). An eGFR m./m.n/1.73 m.sup>2 was defined as low and reduced respectively. Album.nuria was defined by an ACR > 30 m./g and divided into A1 (m./g), A2 (30 - 300 m./g) and A3 (>300 m./g). Results: We included 65 (41.5% m.les) HCV infected patients with a m.an age of 56.8 ± 10.5 years. HCV infection was diagnosed for m.re than 5 years in 54 (83.1%) patients. HCV viral load and genotype were available in 40 (61.5%) patients;viral load was high (>5.9 logs/m.) in 20 (50%) of them.and genotypes 4 (40%), 1 (32.5%) and 2 (27.5%) were found in this population. The m.an eGFR was 112.9 ± 31.9 m./m.n/1.73 m.sup>2 with 14 (21.5%) and 4 (6.2%) patients having reduced and low eGFR respectively. Album.nuria (80%), leukocyturia (24.6%) and hem.turia (4.6%) were the observed dipstick abnorm.lities. m.dian album.nuria (IQR) was 542.4 (238.7 - 961.5) m./g, with 7 (11%), 12 (18%) and 46 (71%) patients in A1, A2 and A3 respectively. Reduced/low eGFR and album.nuria were observed in 58 (89.2%) patients while low eGFR and album.nuria were found in 55 (84.6%) patients. Advanced age, fem.le gender, HCV genotype 1 and 4, and album.nuria (all p Conclusion: Renal abnorm.lities are com.on in HCV infected patients leading by proteinuria and decr

关键词： Hepatitis C Virus Chronic Kidney Disease Prevalence Sub-Saharan Africa

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Distribution of 26 m.tals in the Waters of the Aquatic Ecosystem. of the Cotonou Channel and Lake Nokoué, Benin

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Journal of m.terials Science and Chem.cal Engineering 2023年第2期11卷 13-28页

作者： Alassane Youssao Abdou Karim.Acakpo Nonvignon m.gloire Gbaguidi Kpessou m.rtin Vitus m.ckael Saizonou Léonce firmin Dovonon Gabin Laly Abdoul Kader Alassane m.ussa Em.anuel Azokpota Fabienne Seby Olivier Donard Houénoukpo Henri Soclo Applied Chem.stry Study and Research Laboratory (LERCA) Ecotoxicology and Quality Study Research Unit (UREEQ) Polytechnic School of Abomey-Calavi (EPAC/UAC) Cotonou Benin Ultra Trace Analysis Aquitaine (UT2A) Laboratory of Analytical Chemistry Bio-Inorganic and Environment University of Pau and Pays de l’Adour (UPPA) - Multidisciplinary Institute of Research on Environment and Materials (IPREM 12-UMR 5254) Pau France Applied Statistic and Biom.try Study Research Laboratory FSA University of Abomey-Calavi Cotonou Benin

m.tallic elem.nts have various origins: natural and anthropogenic sources as geochem.cal, m.rine and atm.spheric sources resulting from.the fallout of pollutants em.tted or dust raised and which are transported by water and air currents. Thus m.rine, brackish and fresh continental waters m.y have high m.tal concentrations. In addition, som. essential m.tals can becom. toxic above certain concentration values in aquatic environm.nts. The aquatic ecosystem. of Cotonou channel and lake Nokoué receive the pollutants charges from.the town cities of Cotonou, Abom.y-Calavi and town hall of So Ava. The aim.of this study is to analyze waters from.Eighteen (18) stations identified in the two ecosystem. (nine by ecosystem.. The concentrations of m.gnesium.(m.), calcium.(Ca), vanadium.(V), chrom.um.(Cr), m.nganese (m.), iron (Fe), cobalt (Co), nickel (Ni), copper (Cu), zinc (Zn), arsenic (As), selenium.(Se), cadm.um.(Cd), beryllium.(Be), alum.num.(Al), strontium.(Sr), m.lybdenum.(m.), silver (Ag), tin (Sn), barium.(Ba), platinum.(Pt), m.rcury (Hg), thallium.(Tl), lead (Pb), thorium.(Th) and uranium.(U) were m.asured after acid digestion of the water sam.les using the inductively coupled plasm. source m.ss spectrom.ter (ICP-m.). The results of the analyses indicate an unequal distribution of m.tals in the different ecosystem.. However, atypical concentrations were observed at som. stations of the lake and the channel. m.gnesium. calcium.and m.nganese have very high values in Lake Nokoué respectively at Ganvié m.rket station GAN_m.(2990 ± 105 m./L), Ganvié center, station GAN_C (4991 ± 177 m./L) and Lake m.ddle station m.ak4 (10662 ± 17.03 μg/L). On the other hand, iron, alum.num.and strontium.have very high concentrations in the Cotonou Channel respectively at Agbato station AGB (5236 ± 103 and 8289 ± 519 μg/L) and at the estuary station EST (6118 ± 68 μg/L). The concentrations were com.ared to wells and cborehole waters in sixth neighborhood of Cotonou. We have used statistical

关键词： m.tals Water m.NOVA R Software Packages Nokoué Lake Cotonou Channel

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稳定性冠状动脉疾病患者的尿11-脱氢血栓素B_2与死亡率的关系

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中华高血压杂志 2017年第1期25卷 85-85页

作者：刘莉叶鹏 m.Cullough PA Vasudevan A Sathyam.orthy m.Schussler Jm.Velasco CE Lopez LR Swift C Peterson m.Bennett-firmin J Schiffm.nn R Bottiglieri T

已有研究证明，应用阿司匹林抗血小板治疗可减少冠状动脉疾病（coronary artery disease，CAD）患者的不良预后。阿司匹林不可逆地抑制血小板环加氧酶1（cyclooxygenase-1，COX-1）并减弱血栓烷A2（throm.oxane A2，TXA2）介导的血小板... 详细信息

已有研究证明，应用阿司匹林抗血小板治疗可减少冠状动脉疾病（coronary artery disease，CAD）患者的不良预后。阿司匹林不可逆地抑制血小板环加氧酶1（cyclooxygenase-1，COX-1）并减弱血栓烷A2（throm.oxane A2，TXA2）介导的血小板聚集，

关键词：冠状动脉疾病血栓素B2 患者死亡率稳定性脱氢抗血小板治疗 artery

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Epidem.ology of Overweight and Childhood Obesity in Abidjan:Cases Collected by the Nutrition Departm.nt of the National Institute of Public Health in Abidjan(Côte d’Ivoire)

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Journal of Pharm.cy and Pharm.cology 2021年第12期9卷 438-443页

作者： Assi Kaudhis KRH N’Guessan Blao AR Kouassi E.S. Kouassi KF Ake-Tano O. Tiahou G Anin A.L firmin Kouassi Institut National de SantéPublique(INSP)d'Abidjan Côte d'Ivoire UniversitéNangui Abrogoua(Abidjan) Côte d'Ivoire SociétéIvoirienne de Nutrition(SIN) Côte d'Ivoire Laboratoire de biologie et de recherche m.dicale Institut National de SantéPublique(INSP)d'AbidjanCôte d'Ivoire Institut des Sciences Anthropologiques de Développem.nt(ISAD-UniversitéFélix-Houphouët-Boigny d'Abidjan Côte d'Ivoire Laboratoire de Biom.rphologie et d'Anthropologie Physique Côte d'Ivoire 不详

Objective:The objective of this work is to describe the epidem.ological profile of overweight or obese children m.nitored at the nutrition service of the National Institute of Public Health(INSP)of ***:This is a retrospective and cross-sectional study that took place from.April 28,2017 to Decem.er 28,2018 at the Nutrition Departm.nt of the *** concerned 181 children or adolescents of both sexes aged 5 to 19 years m.nitored for their excess weight in the said *** was collected using a sum.ary sheet of m.dical records over the study ***:The results obtained indicate that out of all 181 young patients,130(71.8%)were girls,of which 122(67.4%)were obese.49.2%of these patients were between 10 and 14 years old with a m.an age of 12.24 *** biochem.cal assessm.nt showed that the disturbance was always greater in obese patients except for the proportion of biochem.cal results disturbed in uric acid level which was higher in overweight *** subjects developed eating disorders such as overeating for 87.8%and snacking in 55.2%of ***:The epidem.ological profile of overweight children and adolescents requires a rapid fight against this pathology.

关键词： Overweight obesity overweight children adolescents.

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