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Incidence and clinical presentation of portal vein thrombosis in cirrhotic patients

Hepatobiliary & Pancreatic Diseases International 2016年第5期15卷 499-503页

作者： Yasir Furkan Cagin Yahya Atayan Mehmet Ali Erdogan firat dagtekin Cemil Colak Division of Gastroenterology Medical Faculty Inonu University Malatya 44280 Turkey Division of Internal Medicine Medical Faculty Inonu University Malatya 44280 Turkey Division of Biostatistics and Medical Informatics Colak C Medical Faculty Inonu University Malatya 44280 Turkey

BACKGROUND: Portal vein thrombosis (PVT) is due to many risk factors, but its pathogenesis is still not clearly understood. To identify the risk factors for PVT, we analyzed the clinical characteristics and complications associated with PVT in cir-rhotic patients. METHODS: We studied patients with liver cirrhosis who were admitted to our unit from April 2009 to December 2014. The patients were divided into the PVT and non-PVT groups, and were compared by variables including gender, age, the etiology of cirrhosis, stage of cirrhosis, complications, imaging, and treatment. RESULTS: PVT was found in 45 (9.8%) of 461 cirrhotic pa-tients admitted to our hospital. Most patients (45.9%) had hepatitis B virus (HBV)-related cirrhosis, with a similar dis-tribution of etiologies between the groups. However, there was no positive relationship between PVT and etiologies of cirrhosis. Most patients (71.5%) were in the stage of hepatic decompensation. No statistically signiifcant differences were found in complications including esophageal varices, ascites, and hepatic encephalopathy between the groups. However, there was a signiifcant positive correlation between hepatocel-lular carcinoma (HCC) and PVT (P CONCLUSIONS: The incidence of PVT was 9.8%, mainly in patients with HBV-related cirrhosis. The development of PVT was associated with the severity of liver disease and HCC.

关键词： portal vein thrombosis cirrhosis clinical presentation

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