检索结果-南通市图书馆

Plasma lipidomics reveal systemic changes persistent throughout early life following a childhood burn injury

Burns & Trauma 2023年第1期11卷 814-824页

作者： Eva Kierath Monique Ryan Elaine Holmes Jeremy K.Nicholson Mark W.Fear fiona M.Wood Luke Whiley Nicola Gray 无 Australian National Phenome Centre Health Futures InstituteMurdoch UniversityHarry Perkins Institute5 Robin Warren DriveMurdochPerthWA 6150Australia fiona Wood Foundation Fiona Stanley HospitalFiona Wood FoundationFiona Stanley HospitalLevel 411 Robin Warren DriveMurdochWA 6150Australia Burn injury research unit School of Biomedical SciencesUniversity of Western Australia6 Verdun streetNedlandsWA 6009 Australia Department of Metabolism Digestion and ReproductionFaculty of MedicineImperial College LondonSir Alexander Fleming BuildingSouth KensingtonLondon SW72AZUK Centre for Computational Medicine Health Futures InstituteMurdoch University5 Robin Warren DriveMurdochPerthWA 6150Australia Medical School University of Western AustraliaHarry Perkins InstituteMurdochPerthWA 6150Australia Faculty of Medicine Institute of Global Health InnovationImperial College LondonLevel 1Faculty Building South Kensington CampusLondon SW72AZUK Burns Service of Western Australia WA Department of Health11 Robin Warren driveMurdochWA 6150Australia Perron Institute for Neurological and Translational Science NedlandsWAAustralia

Background:Non-severe paediatric burns can result in poor long-term health *** occurs even in cases with good acute burn-related outcomes,including minimal *** mechanisms that underpin the transition from non-severe burn to sustained negative long-term health impacts are currently ***,sustained metabolic and immune changes have been observed in paediatric burn studies,suggesting these changes may be *** plasma lipidome consists of a rich pool of bioactive metabolites that play critical roles in systemic processes including molecular signalling and *** hypothesised that changes in the plasma lipidome may reflect underlying changes in health status and be linked to long-term health after burn ***:This study analysed the lipidome in children who had previously experienced a non-severe burn,compared to non-injured ***-three participants were recruited between the ages of 5 and 8 years who had experienced a non-severe burn between the ages of 1 and 3 *** samples were also collected from a non-injured,healthy,age and gender matched control group(n=21).Plasma lipids were measured using reversed-phase liquid chromatographymass spectrometery(LC-MS).Results:In total 838 reproducible lipid species from 19 sub-classes passed quality control procedures and progressed to statistical *** of individual lipid metabolites showed significantly higher concentrations of lysophosphatidylethanolamines and phosphatidylethanolamines,and significantly lower concentrations in myristic,palmitic and palmitoleic acids in the plasma of those who had experienced burn injury compared to ***:Long-term changes in the lipid profile may give insight into the mechanisms underlying poor long-term health subsequent to non-severe burn *** work to investigate the relationship between long-term pathology and lipidomic changes may lead to a better understanding of the causes of seconda

关键词： Lipidomics Lipids Burns Trauma Paediatric Children Mass spectrometry

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

经济发展对中国农村家庭时间分配性别模式的影响

引用

中国农村经济 2009年第12期 77-89页

作者：畅红琴董晓媛 fiona MacPhail 西安交通大学管理学院加拿大温尼伯大学经济系加拿大北哥伦比亚大学经济系

本文运用中国健康与营养调查数据,研究了1991～2006年中国农村的经济发展对农户家庭内部时间分配的性别分工和劳动负担的影响。结果表明,中国农村男性和女性的时间分配都表现出从家庭经营向工资劳动转移的趋势,女性的变化幅度更大一些,... 详细信息

本文运用中国健康与营养调查数据,研究了1991～2006年中国农村的经济发展对农户家庭内部时间分配的性别分工和劳动负担的影响。结果表明,中国农村男性和女性的时间分配都表现出从家庭经营向工资劳动转移的趋势,女性的变化幅度更大一些,而经济发展对男性和女性的家务劳动时间的影响都不显著。研究还发现,经济发展指标的变化与成年男性和女性绝对工作负担的增加以及女性在家庭中相对工作负担的增加显著正相关。

关键词：经济发展时间分配社会性别

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Malaysian cataract surgery registry:incidence and risk factors of postoperative infectious endophthalmitis over a 7-year period

引用

International Journal of Ophthalmology(English edition) 2018年第10期11卷 1685-1690页

作者： Yong Zheng Wai fiona Lee Min Chew Mohamad Aziz Salowi Chai Liang Ang Yong Yuin Chong Tassha Hilda Adnan Pik-Pin Goh Department of Ophthalmology Hospital Tuanku Jaafar Seremban Department of Ophthalmology Hospital Selayang Department of Ophthalmology Faculty of Medicine University Sultan Zainal Abidin Department of Emergency Medicine Hospital Teluk Intan Faculty of Medicine MAHSA University Clinical Research Centre Hospital Kuala Lumpur

AIM：To report the incidence,risk factors and visual outcomes for postoperative endophthalmitis（POE）based on 7-year data from the Malaysian Ministry of Health Cataract Surgery Registry（MOH CSR）.METHODS：Data was collected from the web-based MOH *** consecutive cataract surgery patients from 1st June 2008 to 31st December 2014 were *** criteria were traumatic cataract or previous ocular *** data,ocular co-morbidities,intraoperative details and postoperative visual acuity（VA）at final ophthalmological follow-up were *** eyes were taken for *** with POE were compared against subjects with no POE for risk factor assessment using multiple logistic ***：A total of 163 503 subjects were *** incidence of POE was 0.08%（131/163 503）.Demographic POE risk factors included male gender（OR：2.121,95%CI：1.464-3.015）and renal disease（OR：2.867,95%CI：1.503-5.467）.POE risk increased with secondary causes of cataract（OR：3.562,95%CI：1.740-7.288）,uveitis（OR：11.663,95%CI：4.292-31.693）and diabetic retinopathy（OR：1.720,95%CI：1.078-2.744）.Intraoperative factors reducing POE were shorter surgical time（OR：2.114,95%CI：1.473-3.032）,topical or intracameral anaesthesia（OR：1.823,95%CI：1.278-2.602）,posterior chamber intraocular lens（PCIOL;OR：4.992,95%CI：2.689-9.266）and foldable IOL（OR：2.276,95%CI：1.498-3.457）.POE risk increased with posterior capsule rupture（OR：3.773,95%CI：1.915-7.432）and vitreous loss（OR：3.907,95%CI：1.720-8.873）.Postoperative VA of 6/12 or better was achieved in 15.27%（20/131）subjects with ***：This study concurs with other studies regarding POE risk *** strengthening of MOH CSR data collection process will enable deeper analysis and optimization of POE treatment.

关键词： cataract endophthalmitis eye infection surgery

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

大型无脊椎动物群落指数和群落数量指数在河流水质评价中的应用

引用

应用生态学报 2012年第6期23卷 1682-1688页

作者：高鹏程 Russell G.Death fiona Death 西北农林科技大学资源环境学院陕西杨凌712100 梅西大学理学院自然资源研究所

本文介绍了新西兰常用的大型无脊椎动物群落指数(MCI)和大型无脊椎动物群落数量指数(QMCI)的原理及使用方法,并利用MCI和QMCI对新西兰惠灵顿地区40条河流53个监测点进行评价.结果表明:MCI和QMCI均与河流营养指标呈极显著相关关系,可用... 详细信息

本文介绍了新西兰常用的大型无脊椎动物群落指数(MCI)和大型无脊椎动物群落数量指数(QMCI)的原理及使用方法,并利用MCI和QMCI对新西兰惠灵顿地区40条河流53个监测点进行评价.结果表明:MCI和QMCI均与河流营养指标呈极显著相关关系,可用来监测和评价水体的营养污染状况;二者快速准确地监测出惠灵顿地区河流水质总体良好,但部分河流污染严重,并分析了污染的原因.MCI与QMCI存在极显著相关关系,但MCI与营养指标间的相关关系大于QMCI,可以准确地反映出水体中营养元素的富集状况.

关键词：新西兰大型底栖无脊椎动物群落指数大型底栖无脊椎动物群落数量指数水质监测

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A Study of Challenges and Benefits of Lean Construction(LC)Principles in Omani Construction Industry

引用

Journal of Construction Research 2020年第2期2卷 16-29页

作者： Raj Shah Khalifa Al Shereiqi fiona Borthwick School of Civil Engineering and Built Environment Faculty of Engineering and TechnologyLiverpool John Moores UniversityLiverpoolUK

There are frequent failures in the project delivery in time and increasing the waste in Oman construction *** Construction(LC)principles which are lean thinking in design and construction process may be a possible ***,the paper is aimed on exploring the status of the LC practices and its impact on Omani Construction Industry(OCI).The paper presents barriers,potential benefits,and the measures of suitability and acceptability of LC principles.A quantitative research approach was adopted and research data was collected using an online questionnaire survey in *** data were analysed and results are presented in tables and charts followed by critical *** survey found that onethird of the construction professionals have a good awareness and half of them having a higher level awareness about LC *** than one third of the construction organisations are adopting LC principles with a high consensus on the suitability and acceptability,and they recognised that time commitment is necessary for the successful implementation and achieve *** study concludes that the reduction in project delivery time and construction at site waste is the key advantage of implementing LC priciples in design and construction stages in the omani construction industry.

关键词： Barriers Benefits Challenges Lean construction Lean principles Implementation Industry Oman

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

High prevalence of urinary schistosomiasis in a desert population: results from an exploratory study around the Ounianga lakes in Chad

引用

Infectious Diseases of Poverty 2022年第1期11卷 86-87页

作者： Wendelin Moser Annour Adoum Batil Rebekka Ott Moussa Abderamane Ruth Clements Rahel Wampfler Sven Poppert Peter Steinmann fiona Allan Helena Greter Swiss Tropical and Public Health Institute BaselSwitzerland 不详

Background Researching a water-borne disease in the middle of the Sahara desert might not seem the most relevant ***,nomadic Sahelian pastoralists health concerns regarding their livestock and anecdotal reports about trematode infections of Fasciola *** Schistosoma *** desert-raised animals justified an exploratory study focusing on the lakes of Ounianga in Northern *** aim was to test whether trematode parasites such as Schistosoma *** in human populations living around the Sahara desert lakes of Ounianga Kebir and Ounianga Serir in northern *** The study was carried out in January 2019 and comprised of three ***,a cross sectional survey based on a random sample drawn from the population to detect infections with *** and ***;second,focus group discussions exploring disease priorities,access to health and health seeking behaviour;and third,surveying water contact sites for intermediate host *** of trematode parasites and snails were confirmed on species level by molecular genetic *** parasitological and malacological surveys descriptive statistics were *** data analysis included the full review of all transcripts,followed by a descriptive and explorative thematic *** Among 258 participants,the overall *** prevalence using urine filtration was 39.2%[95%confidence interval(CI):33.5–45.1%],with 51.5%of the infected suffering from heavy *** intermediate host snail of ***(Bulinus truncatus)occurred at water contact sites near both study villages,revealing the potential for local *** a positive *** point-of-care circulating cathodic antigen(POC-CCA)test result was obtained from 8.6%(95%CI 5.7–12.8%)of the samples,no intermediate host snails of *** were found,and the relevance of *** remains *** findings underline the importance of morbidity caused by urinary schistosomiasis

关键词： Bulinus truncatus Chad Malacology Ounianga POC-CCA Prevalence Sahara Schistosoma bovis Schistosoma haematobium Schistosomiasis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ovarian Follicle Disaggregation to Assess Granulosa Cell Viability

引用

International Journal of Clinical Medicine 2018年第5期9卷 377-399页

作者： Mohammad Asaduzzaman Daniela Figueroa Gonzalez fiona Young Medical Biotechnology Flinders University Adelaide South Australia

Background: Mammalian ovaries contain follicles containing an oocyte enclosed by layers of granulosa cells (GC). Follicle growth and oocyte maturation are largely dependent on GC numbers and viability, but there is no established, reliable method for assessing the number of viable GC within an isolated follicle. Methods: Centrifugation conditions and the Trypan Blue (TB) Exclusion assay were optimised for low cell densities compatible with the numbers of GC in follicles. Mouse ovarian follicles were disaggregated to produce a single cell suspension of GC which were examined by TB (n = 4), but also by crystal violet assay in a 96-well plate format after 24 h in vitro (n = 3). GC viability in vitro was characterised further by using enzyme-linked immunoassays to quantify GC production of anti-Mullerian hormone (AMH) and estrogen. Results: The centrifugation and low cell density TB protocol could accurately measure the viability of 78 GC in 10 μL, with an intra-assay coefficient of variation (CoV) 22%, and inter-assay CoV 7%. The best follicle disaggregation method (30 min 37°C exposure to 2 mg/mL collagenase prior to 30 min exposure to 0.025% hyaluronidase) yielded (656 ±87) GC per antral follicle of which 82% ±5% were viable. Culturing 312 - 20,000 GC per well for 24 hours and assessing viability by crystal violet assay generated a linear correlation between OD value and viable GC number (R2 = 0.98) and estrogen concentration per well (R2 = 0.92). 20,000 GC per well produced 143 ±16 pg/mL estrogen during 24 hours in vitro, but no detectable AMH. Conclusion: This is the first report describing the isolation of viable, estrogen-producing GC from murine follicles, and their subsequent culture. These procedures are transferrable to other species including humans and can be applied to screening the reproductive toxicity of pharmaceutical agents.

关键词： Ovarian Follicle Granulosa Cells Viability Collagenase Hyaluronidase

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nurses' views of fundamental relational skills used in clinical practice: a cross-sectional pilot study

引用

Frontiers of Nursing 2021年第3期8卷 223-232页

作者： fiona Timmins Jan M.A.de Vries Yvonne Muldowney Catherine Mc Cabe Jacqueline Whelan Sinead Buckley Sandra McCarthy The School of Nursing and Midwifery Trinity CollegeDublin 2Ireland Portlaoise General Hospital BallyroanPortlaoiseCo.LaoisIreland

Objective:Effective communication skills are one of the core competencies of nursing curricula *** are generally regarded as *** our complete trust in the profession,deficiencies and gaps ***,it is not clear to which extent nurses use key communication skills in practice,and whether or not confident in using these skills compounds environmental issues that *** study explored nurse’s confidence and application of relational skills competencies in nursing ***:A 13-item online survey was used to collect ***:Being self-aware on key areas where there was more *** also lacked confidence in exploring the impact of their personal feelings and values on their *** were also less confident on responding appropriately to instances of unsafe or unprofessional practice and using information and communication systems and ***:Given the potential impact of poor relational skills on quality client care,an increased emphasis on caring and compassion,and the ever-expanding use of communication technologies,there is a need to explore the need for reflective practice to enhance continuous professional development for nurses to enhance their relational skills.

关键词： communication relational nurse caring nursing competencies technology listening

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Significant variations in nutritional supplementation amongst neonates in the United Kingdom

引用

World Journal of Clinical Pediatrics 2016年第3期5卷 325-329页

作者： Morris Gordon Sahira Isaji fiona Tyacke Department of Paediatric Blackpool Victoria Hospital School of Medicine and Dentistry University of Central Lancashire

AIM:To ascertain United Kingdom adherence to European society of Paediatric Gastroenterology,Hepatology and Nutrition guidance(ESPGHAN).METHODS:A national cross sectional questionnaire study of neonatal units across England was completed between January and March *** 174 units in the country were attempted to be contacted to complete a telephone *** included all level 1,2 and 3 *** were initially contacted by phone and asking any senior member of the team about their current practice and *** first ten telephone interviews were completed with two researchers present to ensure consistency of *** no response was received or no details were available,one further attempt was made to contact the *** results were recorded in a proforma and then collated and entered into a spreadsheet for *** to United Kingdom adherence to ESPGHAN guidance was ***:Response rate was 53%.There was variation in use of all *** survey collected data from 91 neonatal units(53%response rate).It was found that 10%of neonatal units had no fixed policy on *** protocols regarding supplementation involved predominantly folic acid,vitamin A,vitamin D and iron,with much variation in doses and *** criteria for prescribing supplements was largely based on age(47%) with only 7%using a weight targets to initiate *** data regarding the appropriateness of each nutritional supplement for a variety of different weights are presented,as well as comparison to ESPGHAN guidance which suggests issues with both underdoing of Breast Fed infants and overdosing of infants on several artificial formulas which already contain significant amounts of these nutritional ***:There is significant heterogeneity in neonatal policies when prescribing supplements to *** policies which take international guidance into account are recommended.

关键词： Neonatal Nutritional additives Preterm nutrition Term nutrition Iron

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Analysing Delay Impact from Potential Risk Factors on Project Delivery of Oil and Gas Pipeline:A Case Study in IRAQ

引用

Journal of Construction Research 2020年第2期2卷 42-55页

作者： LAYTH KRAIDI RAJ SHAH WILFRED MATIPA fiona BORTHWICK Department of the Built Environment Faculty of Engineering and TechnologyLiverpool John Moores University.LiverpoolEnglandUK

The aim of this paper is to present the design and specifications of an integrated Delay Analysis Framework(DAF),which could be used to quantify the delay caused by the Risk Factors(RFs)in Oil and Gas Pipelines(OGPs)projects in a simple and systematic *** main inputs of the DAF are(i)the potential list of RFs in the projects and their impact levels on the projects and the estimated maximum and minimum duration of each *** Carlo Simulation integrated within@Risk simulator was the key process algorithm that used to quantify the impact of delay caused by the associated *** key output of the DAF is the amount of potential delay caused by RFs in the OGP *** functionalities of the developed DAF were evaluated using a case study of newly developed OGP project,in the south of *** is found that the case study project might have delayed by 45 days if neglected the consideration of the RFs associated with the project at the construction *** paper concludes that identifying the associated RFs and analysing the potential delay in advance will help in reducing the construction delay and improving the effectiveness of the project delivery by taking suitable risk mitigation measures.

关键词： Oil and gas pipelines Risk factors Risk analyses Delay analysis framework @Risk Monte carlo simulation Construction delay Time impact

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：