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Science China Earth Sciences 2001年第S1期44卷 45-55页

作者：赖绍聪刘池阳 S.Y.O’reilly

Detailed studies indicate that the main rock type of the Neogene high-potassium calc-alkaline volcanic rock association from north Qiangtang is andesite, dacite and rhyolite. They belong to typical crust-generation magmatic system and originate from the special thickened crust of the Tibetan Plateau by dehydration melting. This group of rocks exhibits LREE enrichment but no remarkable Eu anomaly that shows their source region should be a thickened deep crust consisting of eclogitic mass group, implying that the crust had been thickened and an eclogitic deep crust had been formed during the Neogene period in Qiangtang area. This understanding is important and significant to making further discussion on the uplift mechanism and continental dynamics of the Tibetan Plateau.

关键词： : Neogene volcanism petrology and geochemistry magma source region feature deep crust composition north Qiangtang.

Culprits or consequences:Understanding the metabolic dysregulation of muscle in diabetes

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World Journal of Biological Chemistry 2021年第5期12卷 70-86页

作者： Colleen L O'reilly Selina Uranga James D Fluckey Health and Kinesiology Texas A&M UniversityTX 77843United States

The prevalence of type 2 diabetes(T2D)continues to rise despite the amount of research dedicated to finding the culprits of this debilitating *** muscle is arguably the most important contributor to glucose disposal making it a clear target in insulin resistance and T2D *** skeletal muscle there is a clear link to metabolic dysregulation during the progression of T2D but the determination of culprits vs consequences of the disease has been *** evidence in skeletal muscle implicates influential cross talk between a key anabolic regulatory protein,the mammalian target of rapamycin(mTOR)and its associated complexes(mTORC1 and mTORC2),and the well-described canonical signaling for insulin-stimulated glucose *** new understanding of cellular signaling crosstalk has blurred the lines of what is a culprit and what is a consequence with regard to insulin ***,we briefly review the most recent understanding of insulin signaling in skeletal muscle,and how anabolic responses favoring anabolism directly impact cellular glucose *** review highlights key cross-over interactions between protein and glucose regulatory pathways and the implications this may have for the design of new therapeutic targets for the control of glucoregulatory function in skeletal muscle.

关键词： Insulin resistance Skeletal muscle Mammalian target of rapamycin Glucose uptake Glucose regulation Insulin signaling

A retrospective analysis of pain and opioid usage in head and neck free flap reconstruction

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2023年第2期9卷 153-159页

作者： Parhom Towfighi Alison Hill Jason R.Crossley Amanda Walsh James A.Leonard Jonathan P.Giurintano Matthew L.Pierce Michael J.reilly Georgetown University School of Medicine WashingtonDistrict of ColumbiaUSA Department of Otolaryngology-Head and Neck Surgery Medstar GeorgetownWashingtonDistrict of ColumbiaUSA

Objectives:Investigate opioid usage and postoperative pain in patients undergoing head and neck free flap ***:A retrospective review of 100 consecutive patients undergoing head and neck free flap reconstruction at two academic centers was *** captured included demographics,postoperative inpatient pain,pain at postoperative visits,morphine equivalent doses(MEDs)administration,medication history,and *** were analyzed using regression models,χ2 tests,and student’’***:Seventy-three percent of patients were discharged with opioid medication,with over half(53.4%)continuing to take opioids at their second postoperative visit,and over one-third(34.2%)continuing to take them around 4-month *** out of every five(20.3%)opioid-na?ve patients chronically took opioids *** was a poor association between inpatient postoperative pain scores and daily MEDs administered(R2=0.13,0.17,and 0.22 in postoperative Days 3,5,and 7,respectively).Neither preoperative radiotherapy nor postoperative complications were associated with an increase in opioid ***:For patients undergoing head and neck free flap operations,opioid medications are commonly used for postoperative *** practice may increase the chance an opioid-na?ve patient uses opioids *** found a poor association between MEDs administered and patient-reported pain scores,which suggests that standardized protocols aimed at optimizing analgesia while reducing opioid administration may be *** of Evidence:3(Retrospective cohort study).

关键词： free flap reconstruction head and neck multimodal analgesia opioids postoperative pain

Impact of Social Determinants of Health on the Choice and Use of Long Acting Reversible Contraceptives

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Advances in Reproductive Sciences 2020年第3期8卷 166-174页

作者： Dani Zoorob Connor McNamee Margaret reilly Lindsey Loss James VanHook College of Medicine and Life Sciences The University of Toledo Toledo Ohio USA

Modern women have increased options for birth control with the development of Long Acting Reversible Contraceptives (LARCs). These methods are reliable, easy to use, and require less daily maintenance while providing contraception for an extended period of time. However, despite the surge of LARCs as contraceptive options, the prevalence of unintended pregnancies is still alarmingly high in the United States. As LARCs are the most effective reversible method of birth control at preventing pregnancy, and therefore the potential social, financial, and medical complications associated, we examined whether social determinants of health play a role in LARC usage. While parity and marriage do not seem to affect LARC utilization, increased research is needed to determine the effects of race. Age can affect the type of LARC implemented, as younger women prefer implants to intrauterine devices (IUDs). Insurance coverage was an apparent influencer of LARC usage, as low out-of-pocket costs translate to increased utilization. This is linked to socioeconomic status (SES), as lower SES is associated with decreased access to healthcare in general. Increased research is needed in order to draw conclusions about the effects of education, intimate partner violence, geographic location, and other SDH on LARC usage.

关键词： Social Determinants of Health Long Acting Reversible Contraceptives Intrauterine Devices Disparities Race Family Planning

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Talking business

Talking business

北羌塘新第三纪高钾钙碱火山岩系的成因及其大陆动力学意义

1976年

作者： O''reilly M.

来源：畅想之星图书光盘版（南... 评论

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中国科学（D辑） 2001年第B12期31卷 34-42页

作者：赖绍聪刘池阳 S.Y.O’reilly 西北大学地质系西安710069 National Key Centre of GEMOC Macquarie UniversitySydney 2109Australia

北羌塘新第三纪高钾钙碱系列火山岩主要岩石类型为安山岩、英安岩和流纹岩类,属典型的壳源岩浆系列,是加厚的陆壳基底脱水熔融的产物.岩石具轻稀土富集和无负Eu异常的特殊地球化学特征,表明其源区物质组成相当于榴辉岩相,从而揭示了羌... 详细信息

北羌塘新第三纪高钾钙碱系列火山岩主要岩石类型为安山岩、英安岩和流纹岩类,属典型的壳源岩浆系列,是加厚的陆壳基底脱水熔融的产物.岩石具轻稀土富集和无负Eu异常的特殊地球化学特征,表明其源区物质组成相当于榴辉岩相,从而揭示了羌塘地区在新第三纪板块碰撞这一特定的构造背景下,陆壳已经被加厚并形成了一个榴辉岩质的下地壳类型.

关键词：新生代火山作用岩石地球化学高钾钙碱岩系源区性质下地壳组成北羌塘火山岩

pH-responsive Vesicles with Switchable Corona and Membrane by Direct Dissolution of a Schizophrenic Diblock Copolymer in Water

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pH-responsive Vesicles with Switchable Corona and Membrane b...

Inside server-based applications

2009年全国高分子学术论文报告会

作者：杜建忠 Rachel O'reilly Department of Chemistry University of CambridgeCambridgeCB2 1EWUK Department of Chemistry University of WarwickCoventryCV4 7ALUK

＜正＞Block copolymer vesicles with switchable corona and membrane were prepared by changing the solution pH of a new tertiary amine and amino acid based‘schizophrenic’ pH-responsive block *** diblock copolymer was synthesized by a two-step reversible addition-fragmentation chain-transfer（RAFT） polymerization:（i） A tertiary amine monomer,2-（diethylamino）ethyl methacrylate（DEA）,was polymerized using pyrene-DDMAT[DDMAT is

关键词： Self-assembly block copolymer vesicles pH-responsive

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Inside server-based applications

Vibration stimuli and the differentiation of musculoskeletal progenitor cells: Review of results in vitro and in vivo

2000年

作者： reilly Douglas J

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World Journal of Stem Cells 2015年第3期7卷 568-582页

作者： Jennifer Helen Edwards Gwendolen Clair reilly Kroto Research Institute and INSIGNEO Institute for in silico Medicine Department of Materials Science and Engineering University of Sheffield Institute of Medical and Biological Engineering Faculty of Biological Sciences University of Leeds

Due to the increasing burden on healthcare budgets of musculoskeletal system disease and injury, there is a growing need for safe, effective and simple therapies. Conditions such as osteoporosis severely impact onquality of life and result in hundreds of hours of hospital time and resources. There is growing interest in the use of low magnitude, high frequency vibration(LMHFV) to improve bone structure and muscle performance in a variety of different patient groups. The technique has shown promise in a number of different diseases, but is poorly understood in terms of the mechanism of action. Scientific papers concerning both the in vivo and in vitro use of LMHFV are growing fast, but they cover a wide range of study types, outcomes measured and regimens tested. This paper aims to provide an overview of some effects of LMHFV found during in vivo studies. Furthermore we will review research concerning the effects of vibration on the cellular responses, in particular for cells within the musculoskeletal system. This includes both osteogenesis and adipogenesis, as well as the interaction between MSCs and other cell types within bone tissue.

关键词： Mesenchymal stem cells Mechanobiology Osteogenesis Whole body vibration Adipogenesis,osteoporosis Low magnitude, high frequency vibrationloading

雷州半岛英峰岭玄武岩中的铁铝榴石巨晶及母岩浆成因

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科学通报 2001年第6期46卷 492-497页

作者：于津海 S.Y. O'reilly 南京大学地球科学系内生矿床成矿机制研究国家重点实验室南京210093 GEMOC Department of Earth and Planetary Sciences Macquarie University

英峰岭火山岩中的石榴石巨晶以富铁(>20%)、低镁(5.88%～10.87%)和高钙(6.92%～8.16%)为特征. 成分明显变化, 随着Mg#减小, 石榴石中的Ni, V, Sc, Co和重稀土含量逐渐降低, 而Zr, Hf, Ga, Y, Sr, Nb, Zn和轻、中稀土含量逐渐升高. 石榴... 详细信息

英峰岭火山岩中的石榴石巨晶以富铁(>20%)、低镁(5.88%～10.87%)和高钙(6.92%～8.16%)为特征. 成分明显变化, 随着Mg#减小, 石榴石中的Ni, V, Sc, Co和重稀土含量逐渐降低, 而Zr, Hf, Ga, Y, Sr, Nb, Zn和轻、中稀土含量逐渐升高. 石榴石母岩浆是一种高度演化的残余岩浆, 强烈亏损Ti, Sr, Hf, Nb和重稀土元素. 母岩浆是由石英拉斑质玄武岩浆经60%以上的单斜辉石、石榴石、斜长石和钛铁矿的分离结晶形成. 这种母岩浆没有喷出地表, 而是滞留于地幔结晶成巨晶堆晶岩. 巨晶与寄主岩是非平衡的.

关键词：铁铝榴石巨晶地球化学雷州半岛英峰岭玄武岩母岩浆石榴分离结晶