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Uncertainties of landslide susceptibility prediction considering different landslide types

Journal of Rock Mechanics and Geotechnical Engineering 2023年第11期15卷 2954-2972页

作者： Faming Huang Haowen Xiong Chi Yao filippo Catani Chuangbing Zhou Jinsong Huang School of Infrastructure Engineering Nanchang UniversityNanchang330031China Jiangxi Provincial Key Laboratory of Interdisciplinary Science Nanchang UniversityNanchang330031China Department of Geosciences University of PadovaPadovaItaly Discipline of Civil Surveying and Environmental EngineeringPriority Research Centre for Geotechnical Science and EngineeringUniversity of NewcastleNSW2287Australia

Most literature related to landslide susceptibility prediction only considers a single type of landslide,such as colluvial landslide,rock fall or debris flow,rather than different landslide types,which greatly affects susceptibility prediction *** construct efficient susceptibility prediction considering different landslide types,Huichang County in China is taken as ***,105 rock falls,350 colluvial landslides and 11 related environmental factors are *** four machine learning models,namely logistic regression,multi-layer perception,support vector machine and C5.0 decision tree are applied for susceptibility modeling of rock fall and colluvial ***,three different landslide susceptibility prediction(LSP)models considering landslide types based on C5.0 decision tree with excellent performance are constructed to generate final landslide susceptibility:(i)united method,which combines all landslide types directly;(ii)probability statistical method,which couples analyses of susceptibility indices under different landslide types based on probability formula;and(iii)maximum comparison method,which selects the maximum susceptibility index through comparing the predicted susceptibility indices under different types of ***,uncertainties of landslide susceptibility are assessed by prediction accuracy,mean value and standard *** is concluded that LSP results of the three coupled models considering landslide types basically conform to the spatial occurrence patterns of landslides in Huichang *** united method has the best susceptibility prediction performance,followed by the probability method and maximum susceptibility *** cases are needed to verify this result *** considering different landslide types is superior to that taking only a single type of landslide into account.

关键词： Landslide susceptibility Landslide type Rock fall Colluvial landslides Machine learning models

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Cytokines,synaptic plasticity and network dynamics:a matter of balance

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Neural Regeneration Research 2023年第12期18卷 2569-2572页

作者： Laura Bellingacci Jacopo Canonichesi Andrea Mancini Lucilla Parnetti Massimiliano Di filippo Section of Neurology Department of Medicine and SurgeryUniversity of PerugiaPerugiaItaly

The modern view of the immune system as a sensitizing and modulating machinery of the central nervous system is now well ***,the specific mechanisms underlying this fine crosstalk have yet to be fully *** control cognitive function and behavior,the two systems are engaged in a subtle interacting *** this scenario,a dual action of pro-inflammatory cytokines in the modulation of brain network connections is ***-inflammatory cytokines are indeed required to express physiological plasticity in the hippocampal network while being detrimental when over-expressed during uncontrolled inflammatory *** this dynamic equilibrium,synaptic functioning and the performance of neural networks are ensured by maintaining an appropriate balance between pro-and anti-inflammatory molecules in the central nervous system microenvironment.

关键词： brain networks cognition cytokines hippocampus memory neuroimmunology neuroinflammation synaptic plasticity

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Acupuncture for the management of dry eye disease

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Frontiers of Medicine 2022年第6期16卷 975-983页

作者： Julia Prinz Nicola Maffulli Matthias Fuest Peter Walter Frank Hildebrand filippo Migliorini Department of Ophthalmology RWTH Aachen UniversityPauwelsstr.3052074AachenGermany Department of Medicine Surgery and DentistryUniversity of SalernoVia S.Allende84081BaronissiSAItaly Queen Mary University of London Barts and the London School of Medicine and DentistryMile End Hospital275 Bancroft RoadLondonEI 4DGEngland School of Pharmacy and Bioengineering Keele University Faculty of MedicineThornburrow DriveStoke on TrentEngland Department of Orthopedics University Clinic AachenRWTH Aachen University Clinic52064AachenGermany

The effectiveness of using acupuncture for dry eye disease(DED)is ***,this systematic review investigated the effectiveness and feasibility of using acupuncture for DED in accordance with the 2020 PRISMA *** outcomes of interests were(1)to evaluate the efficacy of acupuncture in improving the ocular surface disease index(OSDI),Schirmer I test score,and tear breakup time from baseline to the last follow-up;(2)to determine possible complications of using acupuncture;and(3)to investigate the superiority of acupuncture over other commonly used treatments for *** from 394 patients were *** showed that acupuncture significantly prolonged the tear breakup time(P<0.0001),significantly increased the Schirmer I test score(P<0.0001),and significantly reduced the OSDI(P<0.0001)from baseline to the last *** with the control group,the acupuncture group had significantly greater Schirmer I test score(P<0.0001),significantly longer tear breakup time(P=0.0004),and significantly lower OSDI(P=0.002).These results suggest that acupuncture is effective and feasible in improving symptoms and signs of *** severe adverse effects of acupuncture were observed.

关键词： dry eye disease xerophthalmus acupuncture

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Uncertainties in landslide susceptibility prediction:Influence rule of different levels of errors in landslide spatial position

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第10期16卷 4177-4191页

作者： Faming Huang Ronghui Li filippo Catani Xiaoting Zhou Ziqiang Zeng Jinsong Huang School of Infrastructure Engineering Nanchang UniversityNanchang330031China Jiangxi Provincial Key Laboratory of Interdisciplinary Science Nanchang UniversityNanchang330031China Department of Geosciences University of PadovaVia Gradenigo 6Padova35131Italy School of Architectural Engineering Jiangxi Science and Technology Normal UniversityNanchang330031China Jiangxi Provincial Science and Technology Affairs Center Nanchang330006China Discipline of Civil Surveying and Conditioning EngineeringPriority Research Centre for Geotechnical Science and EngineeringUniversity of NewcastleNSW2207Australia

The accuracy of landslide susceptibility prediction(LSP)mainly depends on the precision of the landslide spatial ***,the spatial position error of landslide survey is inevitable,resulting in considerable uncertainties in LSP *** overcome this drawback,this study explores the influence of positional errors of landslide spatial position on LSP uncertainties,and then innovatively proposes a semi-supervised machine learning model to reduce the landslide spatial position *** paper collected 16 environmental factors and 337 landslides with accurate spatial positions taking Shangyou County of China as an *** 30e110 m error-based multilayer perceptron(MLP)and random forest(RF)models for LSP are established by randomly offsetting the original landslide by 30,50,70,90 and 110 *** LSP uncertainties are analyzed by the LSP accuracy and distribution ***,a semi-supervised model is proposed to relieve the LSP *** show that:(1)The LSP accuracies of error-based RF/MLP models decrease with the increase of landslide position errors,and are lower than those of original data-based models;(2)70 m error-based models can still reflect the overall distribution characteristics of landslide susceptibility indices,thus original landslides with certain position errors are acceptable for LSP;(3)Semi-supervised machine learning model can efficiently reduce the landslide position errors and thus improve the LSP accuracies.

关键词： Landslide susceptibility prediction Random landslide position errors Uncertainty analysis Multi-layer perceptron Random forest Semi-supervised machine learning

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Linking forest diversity and tree health： preliminary insights from a large-scale survey in Italy

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Forest Ecosystems 2018年第2期5卷 151-161页

作者： filippo Bussotti Matteo Feducci Giovanni Iacopetti Filomena Maggino Martina Pollastrini Federico Selvi Department of Agri-Food Production and Environmental Sciences (DISPAA) University of Firenze Piazzale delle Cascine 18- 50144 Florence Italy Department of Statistical Sciences University La Sapienza P.le Aldo Moro 5 00185 Rome Italy

Forest health is currently assessed in Europe （ICP Forests monitoring program）. Crown defoliation and dieback, tree mortality, and pathogenic damage are the main aspects considered in tree health assessment. The worsening of environmental conditions （i.e., increase of temperature and drought events） may cause large-spatial scale tree mortality and forest decline. However, the role of stand features, including tree species assemblage and diversity as factors that modify environmental impacts, is poorly considered. The present contribution reanalyses the historical dataset of crown conditions in Italian forests from ] 997 to 2014 to identify ecological and structural factors that influence tree crown defoliation, highlighting in a special manner the role of tree diversity. The effects of tree diversity were explored using the entire data set through multivariate cluster analyses and on individual trees, analysing the influence of the neighbouring tree diversity and identity at the local （neighbour） level. Preliminary results suggest that each tree species shows a specific behaviour in relation to crown defoliation, and the distribution of crown defoliation across Italian forests reflects the distribution of the main forest types and their ecological equilibrium with the environment. The potentiality and the problems connected to the possible extension of this analysis at a more general level （European and North American） were discussed.

关键词： Cluster analysis Crown defoliation Forest structure ICP Forests Neighbouring trees Tree diversity Tree identity

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Endoscopic ultrasound-guided biliary drainage after failed endoscopic retrograde cholangiopancreatography: The road is open for almighty biliopancreatic endoscopists!

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World Journal of Gastrointestinal Surgery 2024年第9期16卷 2765-2768页

作者： filippo Antonini Ilenia Merlini Salomone Di Saverio Gastroenterology and Interventional Endoscopy UnitMazzoni Hospital AST Ascoli Piceno Ascoli Piceno 63100Italy Department of Surgery Madonna del Soccorso Hospital AST Ascoli PicenoSan Benedetto del Tronto 63074Italy

Commentary on the article written and published by Peng et al,investigating the role of endoscopic ultrasound(EUS)-guided biliary drainage for palliation of malignant biliary obstruction after failed endoscopic retrograde cholangiopan-creatography(ERCP).For 40 years endoscopic biliary drainage was synonymous with ERCP,and EUS was used mainly for diagnostic *** advent of therapeutic EUS has revolutionized the field,especially with the development of a novel device such as electrocautery-enhanced lumen-apposing metal *** biliopancreatic endoscopists with both skills in ERCP and in interven-tional EUS,would be ideally suited to ensure patients the best drainage technique according to each individual situation.

关键词： Cholestasis Drainage Electrocautery-enhanced lumen-apposing metal stents Endoscopic ultrasound Endosonography Endoscopic retrograde cholangiopancreatogra-phy Interventional procedures Jaundice Malignant Biliary obstruction

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Hepatitis C virus in the new era:Perspectives in epidemiology,prevention,diagnostics and predictors of response to therapy

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World Journal of Gastroenterology 2014年第29期20卷 9633-9652页

作者： filippo Ansaldi Andrea Orsi Laura Sticchi Bianca Bruzzone Giancarlo Icardi Department of Health Sciences University of Genoa Hygiene Unit I.R.C.C.S."A.O.U.San Martino-IST"16132 GenoaItaly

Despite the great successes achieved in the fields of virology and diagnostics,several difficulties affect improvements in hepatitis C virus(HCV)infection control and eradication in the new *** HCV infections still occur,especially in some of the poorest regions of the world,where HCV is endemic and long-term sequelae have a growing economic and health *** HCV vaccine is still no available,despite years of researches and discoveries about the natural history of infection and host-virus interactions:several HCV vaccine candidates have been developed in the last years,targeting different HCV antigens or using alternative delivery systems,but viral variability and adaption ability constitute major challenges for vaccine *** new antiviral drugs for HCV therapy are in preclinical or early clinical development,but different limitations affect treatment *** predictors are important tools,as they provide some guidance for the management of therapy in patients with chronic HCV infection:in particular,the role of host genomics in HCV infection outcomes in the new era of direct-acting antivirals may evolve for new therapeutic targets,representing a chance for modulated and personalized treatment management,when also very potent therapies will be *** the present review we discuss the most recent data about HCV epidemiology,the new perspectives for the prevention of HCV infection and the most recent evidence regarding HCV diagnosis,therapy and predictors of response to it.

关键词： Hepatitis C virus epidemiology Hepatitis C virus diagnosis Hepatitis C virus vaccine Direct-acting antivirals Predictors of response to hepatitis C virus therapy

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Climate Change over China in the 21st Century as Simulated by BCC_CSM1.1-RegCM4.0

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Atmospheric and Oceanic Science Letters 2013年第5期6卷 381-386页

作者： GAO Xue-Jie WANG Mei-Li filippo GIORGI The Laboratory of Climate Study National Climate Center China Meteorological Administration Chinese Academy of Meteorological Science Abdus Salam International Centre for Theoretical Physics

Driven by the global model,Beijing Climate Center Climate System Model version 1.1(BCC_CSM1.1),climate change over China in the 21st century is simulated by a regional climate model(RegCM4.0)under the new emission scenarios of the Representative Concentration Pathways—RCP4.5 and *** is based on a period of transient simulations from 1950 to2099,with a grid spacing of 50 *** present paper focuses on the annual mean temperature and precipitation in China over this period,with emphasis on their future *** of model performance reveals marked improvement of the RegCM4.0 model in reproducing present day temperature and precipitation relative to the driving BCC_CSM1.1 *** warming is simulated by both BCC_CSM1.1 and RegCM4.0,however,spatial distribution and magnitude differ between the *** high emission scenario RCP8.5 results in greater warming compared to *** two models project different precipitation changes,characterized by a general increase in the BCC_CSM1.1,and broader areas with decrease in the RegCM4.0 simulations.

关键词： climate change regional climate model RCP scenarios China

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Managements of recurrent hepatocellular carcinoma after liver transplantation: A systematic review

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World Journal of Gastroenterology 2015年第39期21卷 11185-11198页

作者： Nicola de'Angelis filippo Landi Maria Clotilde Carra Daniel Azoulay Unit of Digestive Hepato-Pancreato-Biliary Surgery and Liver Transplantation Henri-Mondor Hospital Inserm Unité 4394-MACBEth 94010 Créteil France Department of Advanced Biomedical Sciences University Federico Ⅱ of Naples University Paris 7 Denis Diderot Rothschild Hospital Inserm Unité 955-IMRB 94010 Créteil France

AIM: To investigate the efficacy(survival) and safety of treatments for recurrent hepatocellular carcinoma(HCC) in liver transplantation(LT) ***: Literature search was performed on available online databases without a time limit until January 2015. Clinical studies describing survival after HCC recurrence in LT patients were retrieved for a fulltext evaluation. A total of 61 studies were selected: 13 case reports, 41 retrospective case series, and 7 retrospective comparative ***: Based on all included studies, the mean HCC recurrence rate was 16% of all LTs for HCC. A total of 1021 LT patients experienced HCC recurrence. The median time from LT to HCC recurrence was 13 mo(range 2-132 mo). The majority of patients(67%) presented with HCC extra-hepatic recurrences, involving lung, bone, adrenal gland, peritoneal lymph nodes, and rarely the brain. Overall survival after HCC recurrence was 12.97 mo. Surgical resection of localized HCC recurrence and Sorafenib for controlling systemic spread of HCC recurrence were associated with the higher survival rates(42 and 18 mo, res-pectively). However, Sorafenib, especially when combined with m TOR, was frequently associated with severe side effects that required dose reduction or discontinuation CONCLUSION: Management of recurrent HCC in LT patients is challenging and associated with poor prognosis independently of the type of treatment.

关键词： Recurrent hepatocellular carcinoma Liver transplan

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Interference screws *** anchors for isolated medial patellofemoral ligament femoral fixation:A systematic review

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Journal of Sport and Health Science 2022年第1期11卷 123-129页

作者： filippo Migliorini Alice Baroncini Jörg Eschweiler Markus Tingart Nicola Maffulli Department of Orthopaedics University Clinic AachenRheinisch-Westfälische Technische Hochschule(RWTH)Aachen University ClinicAachen 52074Germany Department of Medicine Surgery and DentistryUniversity of SalernoBaronissi 84081Italy School of Pharmacy and Bioengineering School of MedicineKeele UniversityStoke on Trent ST47QBUK Centre for Sports and Exercise Medicine Barts and the London School of Medicine and DentistryMile End HospitalQueen Mary University of LondonLondon E14DGUK

Purpose:The present study aimed to systematically review and compare 2 femoral autograft fixation techniques,namely,interference screws and suture anchors,for isolated medial patellofemoral ligament reconstruction in patients with recurrent patellofemoral instability at mid-to long-term ***:A literature search was performed in September *** studies reporting the outcomes of primary isolated medial patellofemoral ligament reconstruction for recurrent patellofemoral instability were considered for *** studies reporting the type of femoral autograft fixation under examination were *** reporting data from patients with elevated tibial tuberosity-tibial groove,patella alta,and/or Dejour’s trochlear dysplasia types C and D,were not *** articles reporting data with a minimum follow-up period of 18 months were ***:Data from 19 studies(615 patients)were *** overall age was 24.4±6.7 years(mean±SD).The mean follow-up was 46.5±20.9 *** were 76 patients in the anchor group and 539 in the screw *** was found with regard to age and follow-up duration between the 2 study *** was comparability between the Kujala,Lysholm,and Tegner scores at *** the last follow-up,no worthy differences were found in terms of mean Kujala(+2.1%;p=0.04),Lysholm(+1.7%;p=0.05),and Tegner(+15.8%;p=0.05)*** complications occurred almost exclusively in the screw cohort,no statistically significant difference was ***:Femoral autograft fixation through interference screws or suture anchors report similar clinical scores and rate of apprehension test,persistent joint instability,re-dislocations,and *** results must be interpreted within the limitations of the present study.

关键词： Femoral fixation Medial patellofemoral ligament reconstruction Patellofemoral instability

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