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A Panorama of the Urological Diseases at the Former Military Teaching Hospital of Cotonou

Open Journal of Urology 2023年第5期13卷 143-150页

作者： Jean Sossa Lionelle Fanou Yao Félicien Hounto Dodji Magloire Inès Yevi fred Jean-Martin Hodonou Déjinnin Josué Georges Avakoudjo Clinique Universitaire d’Urologie-Andrologie (CUUA) Centre National Hospitalier et Universitaire Hubert Koutoucou Maga (CNHU-HKM) Cotonou Benin

Background: Urological care has been advancing quickly over the last ten years in Benin. In order to conveniently support that trend towards better urological care standards, decision-makers need sound data on urological diseases in the country. Objective: To determine the prevalence of urological diseases in the former Military Teaching Hospital of Cotonou. Patients and Method: We retrospectively collected the urological diseases that the institution had managed from January 2012 to December 2020. We used Excel© 2010 and SPSS© to analyze the collected data. Results: 4244 patients, i.e. 3717 males (87.58%) and 527 females (12.42%) were managed during the study period. The main diseases diagnosed were benign prostatic hyperplasia (32.61%, n = 1384), erectile dysfunction (10.44%, n = 443), chronic prostatitis (5.94%, n = 252), prostate cancer (4.03%, n = 171), and ejaculatory disorders (3.44%, n = 146). In patients ≤ 15 years, predominant diseases were peritoneal vaginal canal (15.9%, n = 43), circumcision (15.6%, n = 42), testicular dystopia (10.7%, n = 29), hydrocele (7.8%, n = 21), and hypospadias (5.6%, n = 15). Wilms tumor (1.9%, n = 5) was the first cancer, testicular (0.4%, n = 1) and para-testicular (0.4%, n = 1) tumors were the next. In patients > 15 and ≤40 years, the main diseases were infertility (14.1%, n = 189), chronic prostatitis (12.9%, n = 173), erectile dysfunction (10.1%, n = 135), ejaculatory disorders (6.2%, n = 83), genital infections (6.2%, n = 83) and urinary stone (4.9%, n = 66). The first cancer was kidney cancer (0.97%, n = 13) followed by bladder cancer (0.3%, n = 4) and testicular tumor (0.3%, n = 4). In patients >40 years, the most prevalent diseases were BPH (52.0%, n = 1370), erectile dysfunction (11.7%, n = 308), prostate cancer (6.5%, n = 171), inguinal hernia (5.1%, n = 134), and urinary stone (3.9%, n = 102). Prostate cancer is the first cancer;the next were bladder (0.95%, n = 25) and kidney (0.68%, n = 18) c

关键词： Urological Diseases Former Military Teaching Hospital of Cotonou

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α-干扰素在猪流感病毒感染急性期的作用

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中国畜牧兽医 2009年第10期36卷 155-155页

作者： filip Barbé 王广秀

细胞因子,尤其是α-干扰素(IFn-α)在控制流感病毒感染过程中发挥着重要作用。为了研究IFn-α在流感过程中的作用,给感染流感病毒的模型动物猪接种IFn-α中和单克隆抗体(Abs)K9。首先确定了IFn-α中和Abs的最佳接种剂量与接种途径,据此... 详细信息

细胞因子,尤其是α-干扰素(IFn-α)在控制流感病毒感染过程中发挥着重要作用。为了研究IFn-α在流感过程中的作用,给感染流感病毒的模型动物猪接种IFn-α中和单克隆抗体(Abs)K9。首先确定了IFn-α中和Abs的最佳接种剂量与接种途径,据此研究Abs对猪流感病毒感染的效果。给猪气管内接种半数鸡胚感染量为106的H1n1流感病毒,接种18 h后,分别给试验猪气管内和腹膜内注射高剂量的IFn-α中和Abs和对照Abs。试验猪分别于接种后0、24、30、487、2 h安乐死。在接种后24和30 h,接种K9猪的气管-肺泡灌洗液中IFn-α明显减少,并伴随IL-6和IL-12的减少,而对照抗体处理组TnF-α和IL-1的水平未受影响。最重要的是,IFn-α中和单克隆抗体处理组动物出现临床症状推迟了24 h,同时伴随IFn-α的减少,但是并没有对病毒的复制及肺脏的病变产生明显的影响。试验结果表明,IFn-α对IL-6和IL-12有诱导作用,3种细胞因子在抗猪流感中起重要作用。

关键词：抗细胞因子疗法 α-干扰素发病机理猪流感病毒

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α-干扰素在猪流感病毒感染期间的作用

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中国畜牧兽医 2010年第5期37卷 25-25页

作者： filip Barbé 张云霞

细胞因子,尤其是α-干扰素对控制流感病毒感染起重要作用。为了研究α-干扰素对控制流感的作用,用猪α-干扰素中和单克隆抗体K9来建立猪流感病毒感染模型。首先,确定α-干扰素中和单克隆抗体最佳剂量和给药途径,基于上述结果来研究单克... 详细信息

细胞因子,尤其是α-干扰素对控制流感病毒感染起重要作用。为了研究α-干扰素对控制流感的作用,用猪α-干扰素中和单克隆抗体K9来建立猪流感病毒感染模型。首先,确定α-干扰素中和单克隆抗体最佳剂量和给药途径,基于上述结果来研究单克隆抗体对猪流感病毒感染的作用。猪气管内接种106.0EID50A/Swine/Belgium/1/98(H1n1)病毒,接毒后18h,气管内和腹腔内注射高剂量α-干扰素中和单克隆抗体和对照抗体,分别于接种后0、24、30、48、72h对动物实施安乐死。在24、30h注射单克隆抗体K9的动物支气管肺泡灌洗液中α-干扰素水平被明显抑制,这与IL-6、IL-12水平降低一致。对照单克隆抗体处理组中α-干扰素和IL-1水平未受影响。重要的是α-干扰素中和单克隆抗体处理的动物临床症状出现和高峰要延迟24h,同时伴随α-干扰素的抑制,但对病毒复制和肺部病变无明显的作用。结果表明,在流感病毒症状中,α-干扰素对IL-6、IL-12诱导及3种细胞因子起重要作用。

关键词：抗细胞因子治疗 α-干扰素发病机理猪流感病毒

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α-干扰素在猪流感病毒感染急性期的作用

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中国畜牧兽医 2009年第12期36卷 174-174页

作者： filip Barbé 王广秀

细胞因子,尤其是α-干扰素(IFn-α)在控制流感病毒感染过程中发挥着重要作用。为了研究IFn-α在流感过程中的作用,给感染流感病毒的模型动物猪接种IFn-α中和单克隆抗体(Abs)K9。首先确定了IFn-α中和Abs的最佳接种剂量与接种途径,据此研究Abs对猪流感病毒感染的效果。给猪气管内接种半数鸡胚感染量为106的H1n1流感病毒,接种18 h后,分别给试验猪气管内和腹膜内注射高剂量的IFn-α中和Abs和对照Abs。试验猪分别于接种后0、24、30、487、2 h安乐死。在接种后24和30 h,接种K9猪的气管—肺泡灌洗液中IFn-α明显减少,并伴随IL-6和IL-12的减少,而对照抗体处理组TnF-α和IL-1的水平未受影响。最重要的是,IFn-α中和单克隆抗体处理组动物出现临床症状的时间推迟了24 h,同时伴随IFn-α的减少,但是并没有对病毒的复制及肺脏的病变产生明显的影响。试验结果表明,IFn-α对IL-6和IL-12有诱导作用,3种细胞因子在抗猪流感中起重要作用。

关键词：抗细胞因子疗法 α-干扰素发病机理猪流感病毒

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α-干扰素在猪流感病毒感染急性期的作用

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中国畜牧兽医 2009年第11期36卷 153-153页

作者： filip Barbé 王广秀

关键词：抗细胞因子疗法 α-干扰素发病机理猪流感病毒

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Challenges Faced by Village Health Teams (VHTs) in Amuru, Gulu and Pader Districts in northern Uganda

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Open Journal of Preventive Medicine 2014年第9期4卷 740-750页

作者： Geofrey Kimbugwe Maghanga Mshilla Denis Oluka Olivia nalikka Joseph Kyangwa Stella Zalwango Uthuman Kilizza Munanura Turyasiima Louis ntambazi fred Walugembe Julius Galiwango Faculty of Medicine Gulu University Gulu Uganda Department of Medical Entrepreneurship Faculty of Medicine Gulu University Gulu Uganda Department of Pharmacology Faculty of Medicine Gulu University Gulu Uganda

Primary health care provision through innovative community level interventions such as the Village Health Team (VHT) concept in Uganda can be a rational way of achieving universal access to healthcare. This cross-sectional study interviewed 150 VHT members and 16 key informants in three districts in northern Uganda to establish the roles of VHTs, the service gaps encountered and the measures in place to address these gaps. Quantitative data were analyzed using SPSS 16.0. Direct content analysis of themes of transcribed qualitative data was conducted manually for common codes. The majority of the respondents 64.29% (n = 72) reported to have been VHT volunteers for more than 5 years. Among the roles were community mobilization reported by 99.1% (n = 111) and home visiting of individuals reported by 97.3% (n = 109). Lack of transport, motivation, adequate skills and community appreciation with nearly no measures in place to counteract the challenges was reported by almost all respondents. Although the VHT concept can be a significant means of achieving universal access to primary health care, extensive community involvement and motivation of the volunteers are highly needed for a maximum benefit.

关键词： VHT Gaps Measures Roles Volunteer

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主密钥问题

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信息安全与通信保密 1984年第1期 45-50页

作者： Dorothg.E,Denning fred.B.Schneider 林子

本文介绍了四种在密码系统中用于产生和分配共用组的加密密钥的方法。这四种方法均可用来在计算机网的许多用户组中实现保密同播。其中有两种方法使用n种密钥来构成2~n-1种密钥的主密钥。

关键词：密钥小组 AS 多项式

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Ventilation practices in burn patients—an international prospective observational cohort study

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Burns & Trauma 2021年第1期9卷 47-57页

作者： Gerie J.Glas Janneke Horn Markus W.Hollmann Benedikt Preckel Kirsten Colpaert Manu Malbrain Ary Serpa neto Karim Asehnoune Marcello Gamma de Abreu Ignacio Martin-Loeches Paolo Pelosi Folke Sjoerg Jan M.Binnekade Berry Cleffken nicole P.Juffermans Paul Knape Bert G.Loef David P.Mackie Perenlei Enkhbaatar nadia Depetris Anders Perner Eva Herrero Lucia Cachafeiro Marc Jeschke Jeffrey Lipman Matthieu Legrand Johannes Horter Athina Lavrentieva Alex Kazemi Anne Berit Guttormsen frederik Huss Mark Kol Helen Wong Therese Starr Luc De Crop Wilson de Oliveira Filho Joa Manoel Silva Junior Cintia M.C.Grion Marjorie Burnett frederik Mondrup Francois Ravat Mathieu Fontaine Renan Le Floch Mathieu Jeanne Morgane Bacus Maite Chaussard Marcus Lehnhardt Bassem Daniel Mikhail Jochen Gille Aidan Sharkey nicole Trommel Auke C.Reidinga nadine Vieleers Anna Tilsley Henning Onarheim Maria Teresa Bouza Alexander Agrifoglio filip fred.n Tina Palmieri Lynda E.Painting Marcus J.Schultz LAMinAR investigators Academic Medical Center University of AmsterdamAmsterdamAZ 1105The Netherlands Department of Anaesthesia and Intensive Therapy Medical University of Lublin Aleje Racklawickie 1–20-059 Lublin–Poland AZ JAn PALFIJn GEnT Watersportlaan 5–9000 Gent–Belgium ABC Medical School SaPauloBangúSP 5001Brazil Service d’Anesthésie Réanimation Chirurgicale Nantes 44093France University Hospital Carl Gustav Carus Dresden 01307Germany St James University Hospital Dublin D08 NHY1Ireland University of Genoa GenoaGE 16128Italy Linkoing University Hospital Linkoing 58185Sweden Maasstad Hospital RotterdamDZ 3079The Netherlands Red Cross Hospital BeverwijkLE 1942The Netherlands Martini Hospital GroningenNT 9728The Netherlands University of Texas Medical Branch GalvestonTX 77555USA Turin CTO Burn Center TurinTO 10126Italy Rigshospitalet Copenhagen 2100Denmark La Paz University Hospital Madrid 28046Spain Ross Tilley Burn Centre Sunnybrook Health Sciences CentreToronto M4N 3M5Canada Royal Brisbane and Women’s Hospital Queensland UniversityHerstonQLD 4029Australia Australian and new Zealand Intensive Care Research Centre.Monash University MelbourneVIC 3004Australia GH St-Louis-Lariboisière APHPParis 75010France BG Klinik Ludwigshafen Ludwigshafen 67071Germany Papanikoalou Hospital Thessaloniki 54621Greece Middlemore Hospital OtahuhuAuckland 2025New Zealand Haukeland University Hospital Bergen 5021Norway Uppsala University Hospital Uppsala 75185Sweden Concord Repatriation General Hospital nSW University of SydneyConcord 2139Australia Ziekenhuis netwerk Antwerpen-Stuivenberg Antwerpen 2060Belgium Universidade de Sao Paulo Sao Paulo 01246-903Brazil Universidade Estadual de Londrina Londrina 86057-970Brazil Sunnybrook Health Sciences Centre Toronto M4N 3M5Canada CHU Lyon St Luc Lyon 69007France CHU nantes Service dánesthesie reanimation chirugicale Nantes 44093France Hopital Roger Salengro CHRU LilleLille 59037France Saint-Louis Hospital Paris 75010France BG University Hospital Bergmannsheil Bo

Background:It is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from *** study aimed to determine ventilation practices in burn intensive care units(ICUs)and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28(VFD-28).Methods:This is an international prospective observational cohort study including adult burn patients requiring mechanical *** tidal volume(V_(T))was defined as V_(T)≤8 mL/kg predicted body weight(PBW).Levels of positive end-expiratory pressure(PEEP)and maximum airway pressures were *** association between V_(T) and VFD-28 was analyzed using a competing risk *** settings were presented for all patients,focusing on the first day of *** also compared ventilation settings between patients with and without inhalation ***:A total of 160 patients from 28 ICUs in 16 countries were *** V_(T) was used in 74%of patients,median V_(T) size was 7.3[interquartile range(IQR)6.2–8.3]mL/kg PBW and did not differ between patients with and without inhalation trauma(p=0.58).Median VFD-28 was 17(IQR 0–26),without a difference between ventilation with low or high V_(T)(p=0.98).All patients were ventilated with PEEP levels≥5 cmH_(2)O;80%of patients had maximum airway pressuresn this international cohort study we found that lung-protective ventilation is used in the majority of burn patients,irrespective of the presence of inhalation *** of low V_(T) was not associated with a reduction in *** registration:*** *** of registration:9 December 2014.

关键词： Mechanical ventilation Inhalation trauma Lung-protective Critical care

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Differences in rates of pelvic lymph node dissection in national Comprehensive Cancer network favorable,unfavorable intermediate-and high-risk prostate cancer across United States SEER registries

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Current Urology 2022年第4期16卷 191-196页

作者： Rocco Simone Flammia Benedikt Hoeh Francesco Chierigo Lukas Hohenhorst Gabriele Sorce Zhen Tian Costantino Leonardo Markus Graefen Carlo Terrone fred Saad Shahrokh F.Shariat Alberto Briganti Francesco Montorsi Felix K.H.Chun Michele Gallucci Pierre I.Karakiewicz Department of Maternal-Child and Urological Sciences Sapienza University RomePoliclinico Umberto I HospitalRome00161Italy Cancer Prognostics and Health Outcomes Unit Division of UrologyUniversity of Montréal Health CenterMontréalQuebecCanada Department of Urology University Hospital FrankfurtFrankfurt am MainGermany IRCCS Ospedale Policlinico San Martino GenovaItaly Martini-Klinik Prostate Cancer Center University Hospital Hamburg-Eppendorf HamburgGermany Department of Urology University Hospital Hamburg-Eppendorf HamburgGermany Department of Urology and Division of Experimental Oncology URIUrological Research InstituteIRCCS San Raffaele Scientific InstituteMilanItaly Department of Urology Comprehensive Cancer CenterMedical University of ViennaViennaAustria Department of Urology Weill Cornell Medical CollegeNew YorkNYUSA Department of Urology University of Texas SouthwesternDallasTXUSA Hourani Center for Applied Scientific Research Al-Ahliyya Amman UniversityAmmanJordan

Background:The national Comprehensive Cancer network(nCCn)guidelines recommend pelvic lymph node dissection(PLnD)in nCCn high-and intermediate-risk prostate cancer *** tested for PLnD nonadherence(no-PLnD)rates within the Surveillance Epidemiology and End Results(2010-2015).Materials and methods:We identified all radical prostatectomy patients who fulfilled the nCCn PLnD guideline criteria(n=23,495).nonadherence rates to PLnD were tabulated and further stratified according to nCCn risk subgroups,race/ethnicity,geographic distribution,and year of ***:Overall,the no-PLnD rate was 26%;it was 41%,25%,and 11%in the nCCn intermediate favorable,intermediate unfavorable,and high-risk prostate cancer patients,respectively(pno-PLnD rates declined in the overall cohort and within each nCCn risk *** exhibited the highest no-PLnD rate(49%),whereas new Jersey exhibited the lowest(15%).Finally,no-PLnD race/ethnicity differences were recorded only in the nCCn intermediate unfavorable subgroup,where Asians exhibited the lowest no-PLnD rate(20%)versus African Americans(27%)versus Whites(26%)versus Hispanic-Latinos(25%).Conclusions:The lowest no-PLnD rates were recorded in the nCCn high-risk patients followed by nCCn intermediate unfavorable and favorable risk in that *** findings suggest that unexpectedly elevated differences in no-PLnD rates warrant further *** all the nCCn risk subgroups,the no-PLnD rates decreased over time.

关键词： Lymph node excision Pelvic lymph node dissection Prostatectomy Prostatic neoplasms

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本能的冲动与成功 1

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丛书名：大师智慧书系

2004年

作者：（奥）弗洛依德（Sigmund fred）文良文化编译

本书包括：记忆的特性、遗忘的本质、数字和迷信、意识与潜意识、无意识的现象、压抑的状态、悲痛与抑郁、诙谐的作用、梦的神秘、自我和本我等25节。

ISBN: (数字)7507516164

ISBN: (纸本)7507516164

关键词：精神分析

来源：汇雅图书（南通市图书馆... 评论

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