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Diagnosis of pancreatic tumors by endoscopic ultrasound-guided fine-needle aspiration

World Journal of Gastroenterology 2007年第22期13卷 3112-3116页

作者： José Celso Ardengh César Vivian Lopes Luiz Felipe Pereira de Lima Juliano Rodrigues de oliveira filadélfi o venco Giulio Cesare Santo José Luiz Pimenta Módena Echoendoscopy and Pathology Units from 9 de Julho Hospital and Ribeiro Preto Medical School-USP So Paulo Brazil

AIM: To evaluate the diagnostic accuracy of endoscopic ultrasound-guided fi ne-needle aspiration (EUS-FNA) for pancreatic solid tumors larger or smaller than 3 cm, and cystic lesions. METHoDS: From January/1997 to December/2006, 611 patients with pancreatic tumors were subjected to EUS-FNA. The fi nal diagnosis was obtained either by surgery (356 cases) or after a mean clinical follow-up of 11.8 mo in the remaining patients. RESULTS: There were 405 solid tumors, 189 cystic lesions and 17 mixed. Pancreatic specimens for cytological assessment were successfully obtained by EUS-FNA in 595 (97.4/) cases. There were 352 (57.6/) malignancies and 259 (42.4/) benign tumors. Among the malignancies, pancreatic adenocarcinomas accounted for 67/ of the lesions. overall, the sensitivity, specifi city, positive and negative predictive values, and accuracy of EUS-FNA were, respectively, 78.4/, 99.2/, 99.3/, 77.2/ and 87.2/. Specif ically for solid tumors, the same parameters for neoplasms larger and smaller than 3 cm were, respectively, 78.8/ vs 82.4/, 100/ vs 98.4/, 100/ vs 99/, 54.8/ vs 74.1/ and 83.1/ vs 87.8/. For cystic lesions, the values were, respectively, 72.2/, 99.3/, 97.5/, 91/ and 92.2/. CoNCLUSIoN: EUS-FNA can be used to sample pancreatic tumors in most patients. Even though the negative predictive value is inadequate for large solid tumors, the results are rather good for small solid tumors, especially concerning the sensitivity, negative predictive value and diagnostic accuracy. Among all pancreatic lesions, EUS-FNA for cystic lesions canreveal the best negative predictive value and diagnostic accuracy, both higher than 90/.

关键词：内窥镜超声波胰腺癌取样诊断组织活检

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Intestinal Protothecosis in a Young Bengal Cat

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open Journal of Veterinary Medicine 2021年第5期11卷 157-164页

作者： Sara Manfredini Luca Formaggini Michele Marino Luigi venco Clinica Veterinaria Lago Maggiore Dormelletto (NO) Italy Laboratorio Analisi Veterinarie La Vallonea Passirana di Rho (MI) Italy

Background: Intestinal protothecosis is an uncommon and insidious mycotic disease. only one human case and a few rare cases in dogs have been reported. To the authors’ knowledge, intestinal protothecosis has never be... 详细信息

Background: Intestinal protothecosis is an uncommon and insidious mycotic disease. Only one human case and a few rare cases in dogs have been reported. To the authors’ knowledge, intestinal protothecosis has never been reported in cats. Case description: This paper describes a case of intestinal protothecosis in a nine-month-old male, Bengal cat. The cat presented because of onset of haemorrhagic diarrhoea. Investigations allowed diagnosis of intestinal protothecosis, confirmed by PCR test on faeces. Treatment with itraconazole did not improve the clinical signs. Treatment with nystatin was prescribed and caused improvement in the clinical signs and decreased number of pathogens seen on faecal cytology. PCR on faecal samples was negative two months after treatment, with complete resolution of symptoms. Conclusion: Infection with Prototheca should be part of the list of differential diagnoses for diarrhoea in cats. nystatin was effective in treating the infection in this case;this drug should be considered as a first-line treatment in cats as well as in dogs, in which ont-family:"">protothecosis appears to have a poor prognosis. Although protothecosis is not considered a zoonotic disease, cases of algal infections in companion animals might be considered indicators of environmental risks for humans.

关键词： Chronic Diarrhoea Haemorrhagic Colitis Feline Medicine Intestinal Protothecosis Prototheca Infection

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