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Biomass gasification,catalytic technologies and energy integration for production of circular methanol:New horizons for industry decarbonisation

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Journal of Environmental Sciences 2024年第6期140卷 306-318页

作者： Luis F.Bobadilla Lola Azancot Miriam González-Castañ Estela Ruíz-López Laura pastor-Pérez Francisco J.Durán-Olivencia Runping Ye Katie Chong Paula HBlanco-Sánchez Zenthao Wu Tomás R.Reina JoséA.Odriozola Departamento de Química Inorgánica e Instituto de Ciencia de Materiales de Sevilla Centro Mixto CSIC-Universidad de SevillaAvda.Américo Vespucio 49Sevilla 41092Spain Departamento de Ingeniería Universidad Loyola AndalucíaAvda.de Las Universidades s/nSevilla 41704Spain Key Laboratory of Jiangxi Province for Environment and Energy Catalysis School of Chemistry and Chemical EngineeringNanchang UniversityNanchang330031China Energy and Bioproducts Research Institute(EBRI) Aston UniversityBirminghamB47ETUnited Kingdom Department of Chemical and Process Engineering University of SurreyGuildfordGU27XHUnited Kingdom

The Intergovernmental Panel on Climate Change(IPCC)recognises the pivotal role of renewable energies in the future energy system and the achievement of the zero-emission *** implementation of renewables should provide major opportunities and enable a more secure and decentralised energy supply *** fuels provide long-term solutions for the transport sector,particularly for applications where fuels with high energy density are *** addition,it helps reducing the carbon footprint of these sectors in the *** on biomass characteristics feedstock is essential for scaling-up gasification from the laboratory to *** review deals with the transformation biogenic residues into a valuable bioenergy carrier like biomethanol as the liquid sunshine based on the combination of modified mature technologies such as gasification with other innovative solutions such as membranes and microchannel *** abatement is a critical process in product gas upgrading since tars compromise downstream processes and equipment,for this,membrane technology for upgrading syngas quality is discussed in this *** reactor technology with the design of state-of-the-art multifunctional catalysts provides a path to develop decentralised biomethanol synthesis from biogenic ***,the development of a process chain for the production of(i)methanol as an intermediate energy carrier,(ii)electricity and(iii)heat for decentralised applications based on biomass feedstock flexible gasification,gas upgrading and methanol synthesis is analysed.

关键词： Biogenic residues Gasification Biomethanol Circular Economy Microreactors

Stay in touch with the endoplasmic reticulum

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Science China(Life Sciences) 2024年第2期67卷 230-257页

作者： Sha Sun Gan Zhao Mingkang Jia Qing Jiang Shulin Li Haibin Wang Wenjing Li Yunyun Wang Xin Bian Yan G.Zhao Xun Huang Ge Yang Huaqing Cai Jose C.pastor-Pareja Liang Ge Chuanmao Zhang Junjie Hu National Laboratory of Biomacromolecules Institute of BiophysicsUniversity of Chinese Academy of SciencesChinese Academy of SciencesBeijing 100101China The Ministry of Education Key Laboratory of Cell Proliferation and Differentiation College of Life SciencesPeking UniversityBeijing 100871China State Key Laboratory of Membrane Biology Tsinghua-Peking Center for Life SciencesSchool of Life SciencesTsinghua UniversityBeijing 100084China Laboratory of Computational Biology&Machine Intelligence School of Artificial IntelligenceUniversity of Chinese Academy of SciencesBeijing 100049China State Key Laboratory of Medicinal Chemical Biology College of Life SciencesNankai UniversityTianjin 300071China Brain Research Center Department of BiologySchool of Life SciencesSouthern University of Science and TechnologyShenzhen 518055China State Key Laboratory of Molecular Developmental Biology Institute of Genetics and Developmental BiologyInnovation Academy for Seed DesignChinese Academy of SciencesBeijing 100101China Institute of Neurosciences Consejo Superior de Investigaciones Científicas-Universidad Miguel HernándezSan Juan de Alicante 03550Spain

The endoplasmic reticulum(ER),which is composed of a continuous network of tubules and sheets,forms the most widely distributed membrane system in eukaryotic *** a result,it engages a variety of organelles by establishing membrane contact sites(MCSs).These contacts regulate organelle positioning and remodeling,including fusion and fission,facilitate precise lipid exchange,and couple vital signaling ***,we systematically review recent advances and converging themes on ER-involved organellar *** molecular basis,cellular influence,and potential physiological functions for ER/nuclear envelope contacts with mitochondria,Golgi,endosomes,lysosomes,lipid droplets,autophagosomes,and plasma membrane are summarized.

关键词： endoplasmic reticulum nuclear envelope mitochondria Golgi apparatus endosome lysosome lipid droplets autophagosome plasma membrane membrane contact site

Low-Cost Tiled Display System Architecture with Dynamic Web-Based Management

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China Communications 2022年第10期19卷 143-168页

作者： Daniel Marfil fernando Boronat F.Javier pastor Anna Vidal Communications Department Gandia CampusUniversitat Politecnica de ValenciaCalle Paraninfo146730Grao de GandiaValencia(Spain) Drawing Department Gandia CampusUniversitat Politecnica de ValenciaCalle Paraninfo146730Grao de GandiaValencia(Spain) Applied Mathematics Department Gandia CampusUniversitat Politecnica de ValenciaCalle Paraninfo146730Grao de GandiaValencia(Spain)

In this paper, a scalable hardware and software architecture for tiled display systems (a.k.a. videowalls), which can be implemented by using low-cost devices, together with a dynamic web-based management and configuration service are proposed. It has been designed to support both stored and live broadcast/broadband content, in mosaic or warp distributions. The displays and devices can be dynamically configured via web in different ways: the displays can create a single display of a larger size;or they can be configured in a customized way in order to playout different media contents in different display combinations. As display renderers, low-cost devices are proposed as the main hardware element to obtain affordable videowall systems. As a proof of concept, two prototypes have been implemented, including an accurate synchronization mechanism based on a Master/Slave control scheme and aggressive and smooth playout adjustment techniques. To evidence the good performance of the prototypes and configuration service, both objective and subjective evaluations have been conducted regarding synchronization accuracy and usability. On the one hand, the mean values of the asynchronies between the video playout processes in each display are kept below 25ms (i.e., frame accuracy). On the other hand, the obtained usability score in the System Usability Scale (SUS) test has been 88.65, which is considered as excellent.

关键词： AMP media synchronization multi-screen playout adjustment tiled displays videowall

Clinical profile and outcomes in very elderly patients with atrial fibrillation anticoagulated with rivaroxaban: data from the EMIR study

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Journal of Geriatric Cardiology 2024年第7期21卷 723-732页

作者： Francisco Marín Manuel Anguita Sánchez Iñaki Lekuona Marcelo Sanmartín Fernán-dez Vivencio Barrios Carlos Perez Muñoz Juan Cosín-Sales Alejandro IPérez Cabeza Vanesa Roldán Schilling Carles Rafols Priu Esteban Orenes-Piñero María Asunción Es-teve-pastor Department of Cardiology Hospital Clínico Universitario Virgen de la ArrixacaIMIB-ArrixacaUniversity of MurciaCIBERCVMurciaSpain Department of Cardiology Hospital Reina Sofía CórdobaIMIBICUniversity of CordobaCIBERCVCórdobaSpain Hospital Galdakao-Usansolo BizkaiaSpain Department of Cardiology Hospital Uni-versitario Ramony CajalCIBERCVMadridSpain Department of Cardiology University Hospital Ramóny CajalAl-caláUniversityMadridSpain Medical Center La Capillita Sanlúcar de Barrameda.Private cardiology clinicJerez de la FronteraSpain Department of Cardiology Hospital Arnau de VilanovaValenciaSpain Department of Car-diology Virgen de la Victoria University HospitalCIBERCV.MalagaSpain Department of Haematology Hospital Clínico Universitario Virgen de la ArrixacaUniversity of MurciaMurciaSpain Department of Medical Affairs Bayer HispaniaBarcelonaSpain Department of Biochemistry and Molecular Biology-A University of MurciaMurciaSpain

Objectives To analyze the clinical profile,adequacy of treatment with rivaroxaban and outcomes in octogenarians with atrial(AF),taking rivaroxaban in clinical *** Out of 1433 patients,453(31.6%)were octogenarians at *** to younger patients,octogenarians had more comorbidities,higher CHA2DS2-VASc(4.5±1.3vs.3.0±1.4;P<0.001)and HAS-BLED scores(2.0±1.0vs.1.4±1.0;P<0.001).Overall,the dose of rivaroxaban was adequately prescribed in 83.4%of patients,but more frequently in the younger population(71.1%vs.89.1%;P=0.039).After a mean follow-up of 2.2±0.6 years,annual rates of stroke+systemic embolism+transient ische-mic attack,MACE,cardiovascular death and major bleeding were 1.03%,1.24%,1.03%and 1.75%,respectively,in octogenarian *** for progressive heart failure death and major bleeding,rates of outcomes in octogenarians were similar com-pared to younger *** octogenarians,the concomitant use of antiplatelet agents and non-severe dementia were independ-ently associated with the development of ischemic stroke,whereas previous coronary revascularization and heart failure with and higher HAS-BLED score with major ***,Conclusions In clinical practice,around one third of patients taking rivaroxaban are *** patients have many comorbidities and a high thromboembolic *** that,rates of adverse events remain *** is adequately pre-scribed in the majority of octogenarians.

关键词： patients atrial bleeding

Idiotype vaccines for lymphoma:Potential factors predicting the induction of immune responses

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World Journal of Clinical Oncology 2011年第6期2卷 237-244页

作者： Susana Inoges Ascension Lopez-Diaz de Cerio Helena Villanueva fernando pastor Elena Soria Maurizio Bendandi Lab of Immunotherapy-Oncology Division Center for Applied Medical ResearchAvda Pio XII5531008 Pamplona(Navarra)Spain Immunotherapy Program Cell Therapy AreaUniversity of Navarra HospitalAvda.Pio XII3631008 Pamplona(Navarra)Spain

Over the last two decades,lymphoma idiotype vaccines have been the first human cancer vaccines to show striking evidence of biological and clinical efficacy on the one hand,as well as clinical benefit on the *** recently,however,three large-scale,independent,randomized clinical trials on idiotypic vaccination have failed to achieve their main clinical endpoints for reasons likely to depend more on flaws in each clinical trial’s study design than on each vaccination strategy per *** of these considerations,a major hurdle for the development of this substantially innocuous and yet potentially very effective type of treatment has been the fact that,even to date,no factors ascertainable before vaccination have been prospectively singled out as predictors of subsequently vaccine-induced,idiotypespecific immune as well as clinical *** aim of this review article is precisely to analyze what has been and what could be done in this respect in order to give a greater chance of success to future trials aimed at regulatory approval of idiotype vaccines.

关键词： Clinical outcome Clinical trial Idiotype Immune response Lymphoma Vaccine

Evaluating human behaviour during a disaster evacuation process:A literature review

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Journal of Traffic and Transportation Engineering(English Edition) 2023年第4期10卷 485-507页

作者： Elnaz Bakhshian Beatriz Martinez-pastor School of Civil Engineering University College DublinIreland

The frequency of natural and man-made disasters has increased over the past few decades,which has doubled the significance of evacuation planning because it directly affects people’s lives and *** evacuees behave during a disaster and the methodologies to assess their behaviour are vital factors in managing any emergency *** example,during the evacuation of a transportation network,users’amount of information and how they react are imperative to achieve a resilient response to a *** though there are numerous approaches for assessing evacuee behaviour,further research is needed to determine how and when each methodology should be *** paper intends to evaluate and classify the methodologies that have been presented up to date to create a more consistent approach to interpreting human behaviour during an evacuation *** majority of studies focus on how people behave during an evacuation of a building,with less attention paid to how they behave during a transport *** the proposed methodologies in this paper,the virtual reality approach,in individual behaviour,and agent-based models,in crowd behaviour,have more advantages than other ***,a comparison between the proposed approaches is made in the discussion *** output of this study provides the classifications and suggestions for researchers to pick an appropriate approach based on the types of problems,and some direction for future studies are *** reach the research goal,177 papers have been reviewed between 1954 and 2022.

关键词： Evacuation planning Human behaviour Transportation network Route choice behaviour Simulation Pedestrians

Conversion of CO_(2)to added value products via rWGS using Fe-promoted catalysts:Carbide,metallic Fe or a mixture?

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Journal of Energy Chemistry 2022年第3期31卷 635-646,I0017页

作者： Q iZhang Laura pastor-Pérez Qiang Wang Tomas Ramirez Reina Department of Chemical and Process Engineering University of SurreyGuildford GU27XHUnited Kingdom College of Environmental Science and Engineering Beijing Forestry UniversityBeijing 100083China

Fe-based catalysts are efficient systems for CO_(2)conversion via reverse water-gas shift(rWGS)***,the nature of the active phase,namely metallic iron,iron oxide or iron carbide remains a subject of debate which our paper is meant to ***0 is a much better catalyst for the rWGS than Fe_(3)*** activity of Fe0 can be promoted by the addition of Cs and Cu whose presence hinders iron carburisation while favouring both higher conversion and enhanced *** the samples are aged in the rWGS reaction mixture during stability test a new phase appear:Fe_(5)C_(2),resulting in a more active but less selective catalysts than Fe0 for the rWGS *** our results indicate that we could potentially achieve an optimal activity/selective balance upon finely tuning the proportion Fe/Fe_(5)C_(2).Beyond the fundamental information concerning active phase we have observed the presence of advanced Fischer-Tropsch-like products at ambient pressure opening new opportunities for the design of hybrid rWGS/Fischer-Tropsch systems.

关键词： CO_(2)conversion rWGS Fe carbide Fe catalysts Hybrid catalysts

On the performance of shared autonomous bicycles:A simulation study

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Communications in Transportation Research 2022年第1期2卷 116-151页

作者： Naroa Coretti Sanchez Inigo Martinez Luis Alonso pastor Kent Larson MIT Media Lab CambridgeMAUSA University of Navarra San SebastianSpain

As society faces global challenges such as population growth and climate change,rethinking cities is now more imperative than *** design of cities can not be abstracted from the design of their mobility ***,efficient solutions must be found to transport people and goods throughout the city efficiently and *** autonomous bicycle-sharing system would combine the most relevant benefits of vehicle-sharing,autonomy,and micro-mobility,increasing the efficiency and convenience of bicycle-sharing systems and incentivizing more people to bike and enjoy their cities in an environmentally friendly *** to the novelty of introducing autonomous driving technology into bicycle-sharing systems and their inherent complexity,there is a need to quantify the potential impact of autonomy on fleet performance and user *** paper presents the results of an agent-based simulation that provides an in-depth understanding of the fleet behavior of autonomous bicycle-sharing systems in realistic scenarios,including a rebalancing system based on demand *** addition,this work describes the impact of different parameters on system efficiency and service ***,it quantifies the extent to which an autonomous system would outperform current station-based and dockless bicycle-sharing *** obtained results show that with a fleet size three and a half times smaller than a station-based system and eight times smaller than a dockless system,an autonomous system can improve overall performance and user experience even with no rebalancing.

关键词： Future mobility Bicycle-sharing systems Autonomous vehicles Micro-mobility Agent-based simulation Multi-agent systems

On the simulation of shared autonomous micro-mobility

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Communications in Transportation Research 2022年第1期2卷 104-115页

作者： Naroa Coretti Sanchez Inigo Martinez Luis Alonso pastor Kent Larson MIT Media Lab CambridgeMAUSA University of Navarra San SebastianSpain

Fast urbanization and climate change require innovative systems for an efficient movement of people and goods in *** trends towards vehicle-sharing,autonomous vehicles,and the use of micro-mobility systems gain strength,the intersection of these fields appears as an area of great *** could potentially bring the convenience of on-demand mobility into already prevalent shared micro-mobility systems(SMMS),increasing their efficiency and incentivizing more people to use active mobility *** novelty of introducing autonomous driving technology into SMMS and their inherent complexity requires tools to assess and quantify the potential impact of autonomy on fleet performance and user *** paper presents an ad-hoc agentbased simulator for the assessment of the fleet behavior of autonomous SMMS in realistic scenarios,including a rebalancing system based on demand *** also allows comparing its performance to station-based and dockless *** proposed simulation framework is highly configurable and flexible and works with high resolution and precision geospatial *** results of studies carried out with this simulation tool could provide valuable insights for many stakeholders,including vehicle design engineers,fleet operators,city planners,and governments.

关键词： Future mobility Autonomous vehicles Micro-mobility Agent-basedsimulation Multi-agentsystems