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Nanoskin®-ACT—The Impact of Natural Membrane & Soft with Chronic and Untreated Wounds

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Journal of Biomaterials and Nanobiotechnology 2024年第3期15卷 39-50页

作者： Saqer Al Mualla Noura Salim Salman Salma Saeed Ns. Nasreen Abdelatif Mohamed Kanjou Gabriel Molina de Olyveira pierre Basmaji Antônio Carlos guastaldi Qassimi Hospital GEM International Sharjah United Arab Emirates Innovatecs-Biotechnology Research and Development So Carlos Brazil UNESp-IQ-physical Chemistry Department Araraquara Brazil

Bacterial cellulose (BC) is a versatile biomaterial with unique properties that make it promising for various biomedical applications, including wound healing. The extracellular matrix (ECM) plays a crucial role in wound healing, providing a structural scaffold and signaling cues for cell migration and proliferation. This study investigates the potential of BC as a scaffold for ECM production and its effect on in vivo wound healing. In this work, the bacterial cellulose fermentation process is modified by the addition of Green propolis and Usnic acid to the culture medium and natural materials before the bacteria are inoculated. In vivo behaviour using natural membranes for regenerative medicine is presented and it is in edit. Overall, our findings demonstrate the potential of BC as a scaffold for ECM production and its beneficial effects on in vivo wound healing. BC-based dressings may offer a novel approach to promoting wound healing and tissue regeneration in clinical settings. Further studies are warranted to optimize BC-based therapies and explore their full potential in regenerative medicine.

关键词： Bacterial Cellulose Biomaterials Nanomedicine Wound Healing Green propolis and Usnic Acid

新疆下三叠统韭菜园组一新小型兽头类（英文）

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古脊椎动物学报(中英文） 2024年

作者：刘俊 fernando ABDALA 中国科学院古脊椎动物与古人类研究所中国科学院大学地球与行星科学学院阿根廷米格尔利洛基金会古生物部南非金山大学进化研究所

主要基于晚二叠世的头部材料，中国近年来报道了多个兽头类物种。记述了新疆韭菜园组的小型包氏兽超科(Baurioidea)新材料，包括一个头骨吻端及咬合的下颌以及两个头后骨架，并命名为迷惑韭菜园颌兽(Jiucaiyuangnathus confusus)。虽然... 详细信息

主要基于晚二叠世的头部材料，中国近年来报道了多个兽头类物种。记述了新疆韭菜园组的小型包氏兽超科(Baurioidea)新材料，包括一个头骨吻端及咬合的下颌以及两个头后骨架，并命名为迷惑韭菜园颌兽(Jiucaiyuangnathus confusus)。虽然标本为幼年个体，新种有以下鉴定特征：上颌骨侧面中部有小圆坑；泪骨与鼻骨接触；前颌骨后端在内鼻孔外侧有容纳下颌齿的窝；犁骨前部侧缘有小型三角形脊向背腹两侧延伸，组成细长的犁骨孔的侧缘；额骨有尖角延伸到鼻骨后侧部；齿骨的联合部收窄并指向前方；5枚前颌骨齿，上下犬齿缺失，前颌骨齿与上颌骨齿间有齿缺，下颌前部无齿缺，10枚上颌骨齿，12枚齿骨齿，后部齿加长，有大的主尖及小的前后副尖；寰椎神经弓与神经棘愈合，枢椎神经棘倒向后方，前乌喙骨孔位于前乌喙骨与肩胛骨间。齿系与小型包氏兽超科成员南非的Ericiolacerta parva及俄罗斯的Silphedosuchus orenburgensis类似。新的头后骨骼材料提供了难得的研究包氏兽超科成员头后骨骼的机会。

关键词：新疆吉木萨尔早三叠世韭菜园组兽头类,包氏兽超科

Enhanced entropy generation and heat transfer characteristics of magnetic nano-encapsulated phase change materials in latent heat thermal energy storage systems

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Applied Mathematics and Mechanics(English Edition) 2024年第6期45卷 1051-1070页

作者： p.S.REDDY p.SREEDEVI Department of Mathematics Rajeev Gandhi Memorial College of Engineering and TechnologyNandyal 518501India

The objective of the current study is to investigate the importance of entropy generation and thermal radiation on the patterns of velocity,isentropic lines,and temperature contours within a thermal energy storage device filled with magnetic nanoencapsulated phase change materials(NEpCMs).The versatile finite element method(FEM)is implemented to numerically solve the governing *** effects of various parameters,including the viscosity parameter,ranging from 1 to 3,the thermal conductivity parameter,ranging from 1 to 3,the Rayleigh parameter,ranging from 102 to 3×10^(2),the radiation number,ranging from 0.1 to 0.5,the fusion temperature,ranging from 1.0 to 1.2,the volume fraction of NEpCMs,ranging from 2%to 6%,the Stefan number,ranging from 1 to 5,the magnetic number,ranging from 0.1 to 0.5,and the irreversibility parameter,ranging from 0.1 to 0.5,are examined in detail on the temperature contours,isentropic lines,heat capacity ratio,and velocity ***,the heat transfer rates at both the cold and hot walls are analyzed,and the findings are presented *** results indicate that the time taken by the NEpCMs to transition from solid to liquid is prolonged inside the chamber region as the fusion temperatureθf ***,the contours of the heat capacity ratio Cr decrease with the increase in the Stefan number Ste.

关键词： volume fraction of nano-encapsulated phase change material(NEpCM) radiation Stefan number heat capacity ratio entropy generation

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A prototype for on-site generation of chlorinated disinfectant for use in rural aqueducts

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Water Science and Engineering 2024年第1期17卷 33-40页

作者： Diana Marcela Cuesta parra Felipe Correa Mahecha Andrés Felipe Rubio pinzon Davidcamilo Ramirez Bustos Leonel Alveyro Teran Llorente Miguel fernando Jimenez Jimenez Chemical and Environmental Engineering Department Fundacion Universidad de AmericaBogota 117111Colombia Chemical Engineering Department Fundacion Universidad de AmericaBogota 117111Colombia Mecanical Engineering Department Fundacion Universidad de AmericaBogota 117111Colombia

Sodium hypochlorite has significant potential as a sanitation solution in hard-to-reach *** studies have investigated the optimal electrolysis parameters for its production with volumes greater than 1o *** study evaluated sodium hypochlorite production through electrolysis in a 22-L prototype and identified the optimal operating *** were performed using graphite electrodes with areas of 68.4 cm^(2) at the laboratory scale and 1865.0 cm^(2) at the prototype scale.A design for experiments with different operating times,chloride concentrations,and electric current intensities was *** optimal operating time,sodium chloride concentration,and current intensity at the laboratory scale were 120 min,150 g of chloride per liter,and 3 A,respectively,leading to the production of 5.02 g/L of the disinfectant with an energy efficiency of 12.21 mg of Cl_(2) per *** the prototype scale,the maximum sodium hypochlorite concentration of 3.99 g of chloride per liter was achieved with an operating time of 120 min,a sodium chloride concentration of 100 g of chloride per liter,and a current intensity of 70 A,reaching an energy efficiency of 42.56 mg of Cl_(2) per *** addition,this study evaluated the influences of the chloride concentration,current intensity,and operating time on the production of sodium hypochlorite at the two scales,and formulated the equations showing the trends of sodium hypochlorite production and energy efficiency in the electrochemical *** 22-L prototype model for production of this oxidizing substance is promising for disinfection of large volumes of water in areas that are difficult to access.

关键词： Disinfection Electrolysis Energy efficiency Optimization Sodium hypochlorite

Novel insights into D-pinitol based therapies:a link between tau hyperphosphorylation and insulin resistance

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Neural Regeneration Research 2024年第2期19卷 289-295页

作者： Dina Medina-Vera Antonio Jesús López-Gambero Juan Antonio Navarro Carlos Sanjuan Elena Baixeras Juan Decara fernando Rodríguez de Fonseca Instituto de Investigación Biomédica de Málaga y plataforma en Nanomedicina-IBIMA plataforma BIONAND UGC Salud MentalMálagaSpain Facultad de Ciencias Universidad de MálagaMálagaSpain CIBER Enfermedades Cardiovasculares(CIBERCV) Hospital Universitario Virgen de la VictoriaUGC del CorazónMálagaSpain University of Bordeaux INSERMNeurocentre MagendieBordeauxFrance Euronutra S.L.Calle Johannes Kepler MálagaSpain Departamento de Bioquímica y Biología Molecular Facultad de MedicinaUniversidad de MálagaMálagaSpain

Alzheimer’s disease is a neurodegenerative disorder characterized by the amyloid accumulation in the brains of patients with Alzheimer’s *** pathogenesis of Alzheimer’s disease is mainly mediated by the phosphorylation and aggregation of tau *** the multiple causes of tau hyperphosphorylation,brain insulin resistance has generated much attention,and inositols as insulin sensitizers,are currently considered candidates for drug *** present narrative review revises the interactions between these three elements:Alzheimer’s disease-tau-inositols,which can eventually identify targets for new disease modifiers capable of bringing hope to the millions of people affected by this devastating disease.

关键词： Alzheimer’s disease cyclin-dependent kinase 5 diabetes D-pinitol inositols insulin resistance kinases phosphorylation pI3K/Akt tau

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A Hybrid Optimization Approach of Single point Incremental Sheet Forming of AISI 316L Stainless Steel Using Grey Relation Analysis Coupled with principal Component Analysiss

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Journal of Wuhan University of Technology(Materials Science) 2024年第1期39卷 160-166页

作者： A Visagan p Ganesh Department of production Technology Madras Institute of TechnologyChennai-600044India

We investigated the parametric optimization on incremental sheet forming of stainless steel using Grey Relational Analysis(GRA) coupled with principal Component Analysis(pCA). AISI 316L stainless steel sheets were used to develop double wall angle pyramid with aid of tungsten carbide tool. GRA coupled with pCA was used to plan the experiment conditions. Control factors such as Tool Diameter(TD), Step Depth(SD), Bottom Wall Angle(BWA), Feed Rate(FR) and Spindle Speed(SS) on Top Wall Angle(TWA) and Top Wall Angle Surface Roughness(TWASR) have been studied. Wall angle increases with increasing tool diameter due to large contact area between tool and workpiece. As the step depth, feed rate and spindle speed increase,TWASR decreases with increasing tool diameter. As the step depth increasing, the hydrostatic stress is raised causing severe cracks in the deformed surface. Hence it was concluded that the proposed hybrid method was suitable for optimizing the factors and response.

关键词： single point incremental forming AISI 316L taguchi grey relation analysis principal component analysis surface roughness scanning electron microscopy

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Research evolution of metal organic frameworks: A scientometric approach with human-in-the-loop

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Journal of Data and Information Science 2024年第3期9卷 44-64页

作者： Xintong Zhao Kyle Langlois Jacob Furst Yuan An Xiaohua Hu Diego Gomez Gualdron fernando Uribe-Romo Jane Greenberg Drexel University 3141 Chestnut StPhiladelphiaPAUSA University of Central Florida 4000 Central Florida BlvdOrlandoFLUSA Colorado School of Mines 1500 Illinois StGoldenCOUSA

purpose:This paper reports on a scientometric analysis bolstered by human-in-the-loop,domain experts,to examine the field of metal-organic frameworks(MOFs)*** analyses reveal the intellectual landscape of a *** study engaged MOF scientists in the design and review of our research *** materials are an essential component in next-generation renewable energy storage and biomedical *** research approach demonstrates how engaging experts,via human-in-the-loop processes,can help develop a comprehensive view of a field’s research trends,influential works,and specialized ***/methodology/approach:Ascientometric analysis was conducted,integrating natural language processing(NLp),topic modeling,and network analysis *** analytical approach was enhanced through a human-in-the-loop iterative process involving MOF research scientists at selected *** researcher feedback was incorporated into our *** data sample included 65,209 MOF research ***3 and software tool VOSviewer were used to perform the ***:The findings demonstrate the value of including domain experts in research workflows,refinement,and interpretation of *** each stage of the analysis,the MOF researchers contributed to interpreting the results and method refinements targeting our focus Research evolution of metal organic frameworks:A scientometric approach with human-in-the-loop on MOF *** study identified influential works and their *** findings also underscore four main MOF research directions and *** limitations:This study is limited by the sample(articles identified and referenced by the Cambridge Structural Database)that informed our *** implications:Our findings contribute to addressing the current gap in fully mapping out the comprehensive landscape of MOF ***,the results will help domain scientists target future research directions.

关键词： Scientometric Metal-Organic Frameworks(MOFs) Network analysis Topic modeling Human-in-the-loop

From BIM model to 3D construction printing:A framework proposal

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Frontiers of Architectural Research 2024年第4期13卷 912-927页

作者： Rodrigo García-Alvarado pedro Soza Ginnia Moroni fernando pedreros Martín Avendaño pablo Banda Cristian Berríos Depto.Diseño y Teoría de La Arquitectura Universidad Del Bío-BíoConcepciónChile Depto.Arquitectura Universidad de ChileSantiagoChile Facultad de Ingeniería Arquitectura y DiseñoUniversidad San SebastiánConcepciónChile Facultad de Arquitectura Arte y DiseñoUniversidad Diego PortalesSantiagoChile

The growth of 3D construction printing needs appropriate integration into the planning and execution phases of building *** this aim,the Architecture,Engineering,and Construction sector(AEC)has been increasingly adopting building information modeling(BIM)systems to synchronize design and construction *** study proposes a technical workflow to manage 3D construction printing into BIM models,evaluating various procedures according to construction element *** on mature software platforms,the research details the data transfer process using a case study of a single-story *** case delves into design procedures for constructing walls of varied shapes,adjustments in width,joints,openings,textures,fillings,and the insertion of reinforcements and services while also discussing requirements of other building *** steps for managing design information and controlling printing machines are *** study’s outcome presents a comprehensive information flow,encompassing model segmentation,geometric data transfer,adjustments of details,and the generation of printing ***,it is offered a discussion that underlines the importance of a synergistic digital information flow that merges both design and execution phases,promoting construction efficiency and the embrace of innovative *** contribution of the paper focuses on technical design strategies for 3D construction printing,but also on suggesting an integrated process.

关键词： 3D construction printing Additive manufacturing Architectural design BIM

Feeding ecology and interactions with mammal hosts in a symbiotic genus of birds(Buphagus spp.)in Namibia

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Avian Research 2024年第3期15卷 336-344页

作者： Michael S.Lukubwe Daniel Velarde-Garcéz fernando Sequeira Susana Lopes Adrian J.F.K.Craig Vanessa A.Mata Department of Zoology and Entomology Rhodes UniversityMakhandaSouth Africa Department of Wildlife Management and Tourism Studies University of NamibiaKatima Mulilo CampusNamibia Departamento de Biologia Faculdade de CiênciasUniversidade do PortoPortoPortugal CIBIO Centro de Investigação em Biodiversidade e Recursos GenéticosInBIO Laboratório AssociadoCampus de VairãoVairãoPortugal BIOpOLIS program in Genomics Biodiversity and Land PlanningCIBIOCampus de VairãoVairãoPortugal

As the sole obligate symbiotic birds in Africa,oxpeckers offer a unique model for studying symbiotic *** to the multitrophic level they occupy and the context dependent foraging behavior they exhibit,the type of symbiotic relationship can be *** addition to providing a cleaning service to the host by removing ticks,oxpeckers frequently feed on blood,mucus,and saliva,inflicting potential damage on the ***,we used DNA metabarcoding on faecal samples to analyze the taxonomic composition of the trophic interactions of the Yellow-billed Oxpecker(Buphagus africanus)and Red-billed Oxpecker(***)in northeastern *** contrast to conventional methods,DNA metabarcoding allows for a detailed identification of dietary resources encompassing both mammal hosts and consumed arthropods within the same *** this information,we examined differences in the diet composition between oxpecker species and localities,as well as the co-occurrence between host and arthropod *** findings revealed that oxpeckers predominantly source their diet from mammals,ticks,and flies;however,ticks and flies rarely co-occur in the diet of an *** observed variability among individuals in their feeding ecology,which is strongly correlated with locality and,to a lesser extent,with the mammal *** noted a high degree of mobility between hosts within relatively short periods,with 32%of the samples showing traces of at least two mammal *** study illustrates the dynamic foraging behavior of these specialized symbiotic birds,shedding light on their potential role in pest control services and disease transmission.

关键词： Commensalism Diet DNA metabarcoding Oxpeckers parasitism Trophic ecology