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Diagnostic value of the combination of TruScreen and Pap smear in screening cervical epithelial lesions: Does it add advantages over the Pap smear alone?

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Open Journal of Obstetrics and Gynecology 2013年第3期3卷 341-346页

作者： Tajossadat Allameh Somayeh Khanjani fereshteh Mohammadizadeh Elaheh Refaei Department of Obstetrics and Gynecology School of Medicine Isfahan University of Medical Science Isfahan Iran Department of Pathology School of Medicine Isfahan University of Medical Science Isfahan Iran School of Medicine Isfahan University of Medical Science Isfahan Iran

Introduction: Pap smear is a well known test in screening of epithelial cell abnormalities of the cervix. However, adding other screening methods to this test may increase the sensitivity and specificity of case finding. Current study has been designed to assess the sensitivity and specificity of the combination of Tru-Screen and Pap tests in comparison to Pap smear alone in women referred for annual screening. Methods: This case-control study was conducted in two groups of 66 and 73 women with epithelial cell abnormality and normal results on Pap smear, respectively. Both groups were subsequently tested with Tru-Screen and colposcopy. Positive finding in any of the three studies made the patient candidate for biopsy as the standard diagnostic test. SPSS software was used to analyze sensitivity, specificity, positive predictive value, and negative predictive value of TruScreen, Pap smear, colposcopy and the combination of TruScreen and Pap tests. Results: 105 out of 139 women underwent biopsy. Of these, 32 (30.5%) had abnormal result in biopsy. Combination of True screen and Pap smear led to a sensitivity of 93.8% and specificity of 79.5% which means an improvement in both parameters. False negative rate decreased to 6.3% but false positive rate increased to 82.2%. Positive and negative predictive values of the combined tests were 33.3% and 86.7%, respectively. Conclusion: Combination of TruScreen and Pap smear is associated with a significant improvement in both sensitivity and specificity for early screening of preneoplastic and neoplastic cervical epithelial lesions.

关键词： TruScreen Pap Smear Colposcopy Biopsy Cervical Epithelial Lesions

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Self Evaluation in Department of Communicable Diseases, Faculty of Medicine, Tehran University of Medical Sciences

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Health 2014年第16期6卷 2197-2203页

作者： fereshteh Farzianpour Mahbobeh Hajabdolbaghi Siross Jafary Hamid Emady Kochak Department of Health Management and Economic School of Public Health Tehran University of Medical Sci-ences Tehran Iran Members of Educational Evaluation Committee of Communicable Diseases Faculty of Medicine Tehran University of Medical Sciences Tehran Iran

Introduction: Self evaluation is a process that defines and collects required data to judge about decision making issues at educational system on whether the educational department is fit to educate students? The objective of this study was determining the quality of the structural elements of the department of Communicable Diseases & determining the strengths, weaknesses, opportunities and threats to improve the quality of activities in the department under research. Materials and Methods: The employed method was Mixed methods (qualitative & quantitative research), on the basis of 10 procedural steps and within 8 sections dealing with evaluated factors;such as 1) organizational and management structure 2) scientific board members 3) students 4) Manpower 5) Space of educational research and health care 6) Equipment 7) curriculum 8) satisfaction of graduates, which were studied using 61 criteria and 172 indicators. Five-point Likert Scale was used for the responses in the questionnaire (1 - 1.75 = undesirable, to 4.2 - 5 completely desirable). Finally the data were analyzed using descriptive statistics indices and the assessment software of the Educational Development Center of TUMS. The instruments used in this method included assessment software, interview, observation and self-prepared questionnaire which consisted of 7 questionnaires and 2 check lists. Finding: The results of the research showed that general average of 8 investigating sections was 56.9% as a rather desirable research work. Conclusions: Therefore, it was concluded that function of the educational management in that group was directly in line with evaluation process, but continuing the process of evaluation seems necessary.

关键词： Self Evaluation Department of Communicable Diseases Faculty of Medicine Tehran University of Medical Sciences Educational Management

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Chiral Recognition of Binaphthyl Derivatives with L-Undecyl Leucine Surfactants in the Presence of Sodium and Lysine Counterions

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American Journal of Analytical Chemistry 2021年第5期12卷 188-201页

作者： Mauro Garcia Amanda Risley fereshteh Billiot Eugene Billiot Kevin Morris Department of Physical and Environmental Sciences Texas A&M University-Corpus Christi Corpus Christi USA Department of Chemistry Carthage College Kenosha USA

This study investigates the effect of counterions on the chiral recognition of 1,1'-Binaphthyl-2,2'-diamine (BNA) and 1,1'-Binaphthyl-2,2'-diyl hydrogenphosphate (BNP) enantiomers when using an amino acid-based surfactant undecanoyl L-leucine (und-Leu) as the chiral pseudostationary phase in capillary electrophoresis. The effects of using two different counterions (sodium and lysine) on the chiral recognition of binaphthyl derivatives were compared at varying pH conditions. The enantiomeric separation of BNA and BNP enantiomers via capillary electrophoresis, using und-Leu as the chiral recognition medium, significantly improved the enantiomeric resolution in capillary electrophoresis at pH 7 when using Lysine counterions as compared to using sodium as the counterion. More specifically, at a surfactant concentration of 45 mM, at pH 7, a significant increase in chiral selectivity was observed when lysine was used as the counterion compared to sodium. The enantiomeric resolution of BNA and BNP increased by 6-fold and 1.1-fold, respectively, in capillary electrophoresis experiments when lysine was utilized as the counterion compared to using sodium. Furthermore, the retention factor of BNA and BNP enantiomers also increased approximately 3.5-fold and 4-fold, respectively, in the presence of lysine counterions as compared to using sodium counterions. When running buffer in capillary electrophoresis was increased to pH 11, the resolution and retention factors were nearly identical when comparing the effects of the sodium and lysine counterions. This signifies the important role of lysine’s positive net charge on chiral recognition. This study provides insight into the potential advantages of using cationic, pH-dependent counterions such as lysine to significantly improve the chiral recognition of binaphthyl derivatives when using chiral anionic surfactants as the pseudostationary phase in capillary electrophoresis.

关键词： Lysine Binaphthyl Counterions Chiral Recognition Amino Acid-Based Sur-factants Micellar Electrokinetic Chromatography

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Assessing Demographic Factors Related to Maternal Mortality in Tehran Province, Iran from 2008 to 2011

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Health 2015年第3期7卷 308-315页

作者： fereshteh Farzianpour Abbas Rahimi Foroushani Nasrin Changizi Khatere Ramezani Department of Health Management and Economics School of Public Health Tehran University of Medical Sciences Tehran Iran Department of Epidemiology and Biostatistics Tehran University of Medical Sciences Tehran Iran Department of Health for Maternal Health Tehran Iran

The rate of maternal mortality due to complications of pregnancy and delivery is one of the most significant indicators showing the development state of countries. The purpose of the present study is to assess important indicators of maternal health and predisposing factors of maternal mortality in Tehran province from 2008 to 2011. The present study is a case-control one. All mothers who had lost their life (n = 113) were selected through census and survived mothers (n = 327) through randomized stratified sampling. Statistical analysis was performed using SPSS V.22, X2 test, Fishers exact test and Logistic regression. The rate of maternal mortality was the highest (29.2%) in 2009 and the lowest (20.4%) in 2011. Variables type of maternity hospital (P-value = 0.036), maternal education (P-value < 0.001), husband’s education (P-value < 0.001) had a significant relation to maternal mortality. Logistic regression analysis showed that there is a relationship between the education level of the husband and maternal mortality. Considering the factors affecting maternal mortality, promoting hospital services, improving skills and knowledge of doctors, midwives and nurses and strengthening educational programs for the illiterate are the most effective measures to reduce maternal mortality.

关键词： Assessing Demographic Factors Maternal Mortality Tehran Province Iran

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The Relationship between Quality of Life with Demographic Variables of Elderly in Golestan Province-Iran

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Health 2015年第5期7卷 507-513页

作者： fereshteh Farzianpour Abbas Rahimi Foroushani Abbas Badakhshan Mahin Gholipour Department of Health Management and Economics School of Public Health Tehran University of Medical Sciences Tehran Iran Department of Epidemiology and Biostatistics School of Public Health Tehran University of Medical Sciences Tehran Iran Golestan Research Center of Gastroenterology and Hematology Golestan University of Medical Sciences Gorgan Iran

Quality of life subscales was influenced by different factors including age, gender, and financial status and more importantly by health, education, financial and marital status. The main goal of this study was relationship between (QOL) with demographic variables of elderly in Golestan province-Iran. This research was an analytical cross study that conducted on 193 individuals going to Jahandidegan geriatric charity institution of Golestan-Iran. The data were collected from questionnaire SF-36 for QOL the elderly indicators through interviews and observation and then analyzed using SPSS V.17 Software. Among QOL dimensions, only general health status showed a significant association with supporting organizations covering status (P = 0.01). The relationship between QOL with current employment status in both genders was observed.

关键词： Quality of Life Elderly Questionnaire (SF36) Variables Demographic

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Sulfuric Acid Immobilized on Silica Gel as Highly Efficient and Heterogeneous Catalyst for the One-Pot Synthesis of 2,4,5-Triaryl-1H-imidazoles

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International Journal of Organic Chemistry 2012年第1期2卷 93-99页

作者： Behrooz Maleki Hossein Keshvari Shirvan fereshteh Taimazi Elahe Akbarzadeh Department of Chemistry Sabzevar Tarbiat Moallem University Sabzevar Iran Department of Chemistry Tarbiat Moallem University Tehran Iran

Application of sulfuric acid immobilized on silica gel as an efficient and benign catalyst has been explored in the syn-thesis of 2,4,5-Triaryl-1H-imidazoles via condensation reaction of benzil or benzoin, aldehyde and ammonium acetate. The key advantages of this process are high yields, cost effectiveness of catalyst, easy work-up, purification of products by non-chromatographic method and the reusability of the ***2 catalyst.

关键词： 2 4 5-Trisubstituted Imidazoles Solvent-Free Synthesis Multicomponent Reaction Silica-Supported Sulfuric Acid Heterogeneous Catalyst

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Evaluation of Comparative Management of Expanded Program Immunization for Children in Iran and in the World

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Health 2014年第19期6卷 2697-2704页

作者： fereshteh Farzianpour Kobra Bamdad Mehrabani Nayeb Fadaei Dehcheshmeh Mohammad Azmal Department of Health Management and Economics School of Public Health Tehran University of Medical Sciences Tehran Iran Department of Immunology School of Medicine Tehran University of Medical Sciences Tehran Iran

Background: EPI is one of the most cost-effective public health interventions that have already been identified. Mass vaccination is one of the most effective public health strategies that lead to a dramatic reduction in the incidence of many infectious diseases. This is a descriptive study (eco-logical exploratory) where data about the status of routine immunization of children under 6 years in 6 selected countries in terms of the routine immunization programs in each country, the coverage and reported cases of vaccine-preventable diseases from 2006 to 2008 were collected assuming that each country is a representative of a Continent;data about the status of Iran were also collected and a comparative study was performed in the next step. It is worth mentioning that selecting these countries was according to health experts to consolidate the data. Collection tools are data of international (WHO and UNICEF) and national organizations of the above countries. In all countries surveyed, triple vaccine, vaccines of polio, hepatitis B, measles, rubella and mumps are part of the routine immunization program for children under the age of 6 years, with the explanation that in South Africa only measles vaccine is injected instead of measles, rubella and mumps vaccines. The coverage rate of the vaccine and other vaccines in Iran was the best compared to other countries. This represents the widespread activity of health care systems of the country in the field of vaccination and tireless efforts of healthcare workers and health centers.

关键词： Evaluation Comparative Management Program Immunization Children Iran World

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Prevalence and characteristic of Campylobacter species isolated from raw duck and goose meat in Iran

Prevalence and characteristic of Campylobacter species isola...

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International Conference on Food Engineering and Biotechnology（ICFEB 2011）

作者： Ebrahim Rahimi Foroogh Alian fereshteh Alian Membership of Young Researches Club Shahrekord BranchIslamic Azad University-Shahrekord-Iran Department of Food Hygien Shahrekord BranchIslamic Azad University-Shahrekord-Iran

Poultry meat is frequently contaminated with Campylobacter strains and is thought to be the major source of organisms causing human Campylobacter *** study was conducted to determine the prevalence and antimicrobial resistance of Campylobacter *** from retail duck and goose raw meats in *** August 2009 to August 2010,a total of 169 raw duck and goose meat samples were purchased from randomly selected retail outlets in Gilan province,Iran and were evaluated for the presence of *** conventional bacteriological methods,39 of 110 duck meat samples（35.5%） and 13 of 49 goose meat samples（26.5%） were contaminated with Campylobacter,*** most prevalence Campylobacter species isolated from samples was Campylobacter jejuni（88.5%）;the remaining isolates were Campylobacter coli（11.5%）.All of Campylobacter identified as Campylobacter jejuni and Campylobacter coli by using conventional bacteriological method were also positive Using the PCR *** of 52 Campylobacter isolates were determined for ten antimicrobial drugs using the disk diffusion *** to ciprofloxacin was the most common finding（40.4%）,followed by resistance to tetracycline（32.7%） and nalidixic acid（30.8%）.Significantly higher prevalence rates of Campylobacter spp.（P＜0.05） were found in samples taken in spring and *** our knowledge,the present study is the first report of the isolation of Campylobacter *** raw duck and goose meat in Iran.

关键词： Campylobacter,raw poultry meat,duck goose,antimicrobial resistance

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A Study on the Feasibility of Total Quality Management Model and the Awareness and Attitude of the Managers of Health Care

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Health 2015年第2期7卷 231-237页

作者： fereshteh Farzianpour Kazem Mohammad Abbas Rahimi Foroushani Samira Alirezaei Fatemeh Manafi Department of Health Management and Economics School of Public Health Tehran University of Medical Sciences Tehran Iran Department of Epidemiology and Biostatistics School of Public Health Tehran University of Medical Sciences Tehran Iran School of Health Management and Information Sciences Iran University of Medical Sciences Tehran Iran

Total Quality Management is not just an admirable phenomenon but it is any client’s right and can be done through contribution of the staff and the managers as well as the client’s of an organization. The purpose of the present study is to investigate the feasibility of TQM model and the attitude of the managers of health field of Yazd medical sciences university towards it. The present study was a descriptive and analytical one which was cross-section ally conducted from 2010 to 2011. The population under study consisted of the managers of the unit of staff vice-chancellor for health and treatment, the managers of health system and centers of cities and also the managers of Yazd’s public hospitals. 64 people were chosen using the formula for calculating the number of samples. A questionnaire with 48 questions was used. The questionnaire’s validity was approved by the faculty members whose major is management and its reliability by using α-cronbach 87%. To analyze the data, the software SPSS V.17 was used. Scoring method was based on likert. The findings of the study show that, considering feasibility of TQM, there is a significant relation between the awareness and attitude of the managers of health and treatment field on one side and the variables, age and University degree, on the other side p = 0.001. Considering binary logistic regression and the results obtained in the form of inter and backward stepwise, the most important factors affecting the feasibility of TQM among the managers of health and treatment field are the level of awareness and attitude with the predicted accuracy 79.3% and 87.9% respectively.

关键词： Feasibility Total Quality Management Model Awareness Attitude Managers of Health Field

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Evaluating the average access to care and continuity of care patients in Tehran teaching hospitals

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Health 2013年第12期5卷 2110-2115页

作者： fereshteh Farzianpour Searajadein Gray Abbas Rahimi Foroushani Mohammad Arab Shadi Hosseini Department of Epidemiology and Biostatistics School of Public Health Tehran University of Medical Sciences Tehran Iran Department of Health Management and Economic School of Public Health Tehran University of Medical Sciences Tehran Iran Department of Management Management Faculty Tehran University Tehran Iran

Background: Standards of Joint Commission International emphasize on the organizational performance level in basic functional domains including patient right, patient care, medical safety and infection control. These standards are focused on two principles: expectations of the actual organizational performance and assessment of organizational capabilities to provide high quality and safe health care services. The aim of this study is to evaluate the possibility of improvement in Access to Care and Continuity of Care for patients (ACC) in teaching hospitals of Tehran University of Medical Sciences. Methods: This cross-sectional study was conducted in hospitals affiliated to Tehran University of Medical Sciences during 2012. Data collection was performed using author-designed questionnaire of “Access to Care and Continuity of Care patients” based on JCI standards (2013). A total of 171 questionnaires were sent to 26 hospitals and 154 (90%) questionnaires were successfully completed and used for data analysis. The questionnaire was reviewed by experts and the Cronbach’s alpha was calculated to be 0.967. The effects of the two variables of hospital type (general, specialty) and the number of beds on mean scores of ACC standards and each of its domains were analyzed using T-test or Mann-Whitney test depending on the distribution due to Kolmogorov-Smirnov test result. Results: In general, the mean of ACC standards was found comprehendible and applicable by 82.3 (SD = 11) of the respondents. The highest and lowest mean scores of ACC questions belonged to hospitals H21 (90 ± 6) and H14 (67 ± 12), respectively. There were not any significant effects of hospital type and the number of beds on the ACC scores. Conclusion: There was not any important effect of hospital type and bed numbers on ACC, although there was a 9%-15% possibility of improvement in accreditation scores of ACC standards in hospitals of Tehran University of Medical Sciences. A complete accreditation score in

关键词： Accreditation Access to Care and Continuity of Care Patients Joint Commission International Hospitals of Tehran University of Medical Sciences

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