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无限维希尔伯特空间上保密度算子凸组合的一般熵映射

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数学理论与应用 2023年第2期43卷 82-91页

作者：贾凤阳张艳芳贺衎渭南师范学院数学与统计学院渭南714000 太原理工大学数学学院太原030024

令H是无限维复希尔伯特空间,S(H)是H上密度算子的集合,即在H上为正且迹为一的有界线性算子的全体.本文给出在S(H)上保密度算子凸组合的一般熵映射的刻画.

关键词：广义熵密度算子熵保持

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惯性/视觉组合导航在不同应用场景的发展

导航定位学报 2016年第4期4卷 30-35页

作者：李丰阳贾学东董明信息工程大学导航与空天目标工程学院河南郑州450001 地理信息工程国家重点实验室陕西西安710054 卫星导航工程中心北京100094

针对惯性导航难以满足长时高精度的需求问题,提出利用视觉导航对相对导航信息敏感、精度随距离减少而提高的特点,来弥补惯性导航在水下、深空等封闭或复杂环境下的不足:根据地面、空中、水下和深空4种不同的应用场景,归纳惯性/视觉组合... 详细信息

针对惯性导航难以满足长时高精度的需求问题,提出利用视觉导航对相对导航信息敏感、精度随距离减少而提高的特点,来弥补惯性导航在水下、深空等封闭或复杂环境下的不足:根据地面、空中、水下和深空4种不同的应用场景,归纳惯性/视觉组合导航的发展现状;并对不同应用环境对惯性/视觉组合导航系统的需求和指标进行比较;最后展望惯性/视觉组合导航的发展趋势。

关键词：视觉导航惯性导航组合导航联合精确空投系统火星探测器

A Comprehensive Study of the Association between LEPR Gene rs1137101 Variant and Risk of Digestive System Cancers

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Biomedical and Environmental Sciences 2024年第5期37卷 445-456页

作者： HU Wei Qiong ZHOU Wei Guang ZHOU Guang Wei LIAO jia Xi SHI jia Xing XIE fengyang LI Shou Heng WANG Yong FENG Xian Hong GU Xiu Li CHEN Bi Feng Department of Biological Science and Technology School of ChemistryChemical Engineering and Life SciencesWuhan University of TechnologyWuhan 430070HubeiChina Institute of WUT-AMU Wuhan University of TechnologyWuhan 430070HubeiChina Department of Clinical Laboratory Wuhan Xinzhou District People’s HospitalWuhan 430499HubeiChina Department of Reproductive Genetics Wuhan Huake Reproductive HospitalWuhan 430013HubeiChina

Objective The leptin receptor,encoded by the LEPR gene,is involved in tumorigenesis.A potential functional variant of LEPR,rs1137101(Gln223Arg),has been extensively investigated for its contribution to the risk of digestive system(DS)cancers,but results remain conflicting rather than ***,we performed a case–control study and subsequent meta-analysis to examine the association between rs1137101 and DS cancer *** A total of 1,727 patients with cancer(gastric/liver/colorectal:460/480/787)and 800 healthy controls were *** of rs1137101 was conducted using a polymerase chain reactionrestriction fragment length polymorphism(PCR-RFLP)assay and confirmed using Sanger ***-four eligible studies were included in the *** After Bonferroni correction,the case–control study revealed that rs1137101 was significantly associated with the risk of liver cancer in the Hubei Chinese *** meta-analysis suggested that rs1137101 is significantly associated with the risk of overall DS,gastric,and liver cancer in the Chinese *** The LEPR rs1137101 variant may be a genetic biomarker for susceptibility to DS cancers(especially liver and gastric cancer)in the Chinese population.

关键词： LEPR gene rs1137101 Digestive system cancers Genetic susceptibility Meta-analysis

Inhibition of β-ionone on SGC-7901 cell proliferation and upregulation of metalloproteinases-1 and -2 expression

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World Journal of Gastroenterology 2004年第2期10卷 167-171页

作者： jia-RenLiu Bao-fengyang Bing-QingChen Yan-MeiYang Hong-WeiDong You-QiangSong PublicHealthCollege HarbinMedicalUniversityHarbin150001HeilongjiangProvinceChina DepartmentofPharmacology HarbinMedicalUniversityHarbin150086HeilongjiangProvinceChina DepartmentofBiochemistryandtheGenomeResearchCentre TheUniversityofHongKongHongKongChina

AIM:To observe the effect of β-ionone on the proliferation of human gastric adenocarcinoma cell line SGC-7901 and the inhibition of ***:Using growth inhibition, Zymograms assays and reverse transcription-polymerase-chain reaction (RT-PCR),we examined cell growth rates,activities of matrix metalloproteinases-2 (MMP-2) and-9 (MMP-9),and expression of metalloproteinases-1 (TIMP-1) and-2 (TIMP-2) in SGC-7901 cells after the treatment with β-ionone for 24 h and 48h, ***:β-ionone had an inhibitory effect on the growth of SGC-7901 *** days after the treatment with β-ionone at concentrations of 25, 50, 100 and 200μmol/L,the inhibition rates were 25.9%, 28.2%, 74.4% and 90.1%,respectively. The IC50 value of β-ionone for SGC-7901 cells was estimated to be 89μmol/*** effects of β-ionone on MMP-2 and MMP-9 activities in SGC-7901 cells were not observed. However,the levels of TIMP-1 and TIMP-2 transcripts were elevated in cells treated with β-ionone in a dose-dependent ***:β-ionone can inhibit the proliferation of SGC-7901 cells,upregulate the expression of TIMP-1 and TIMP-2 expression, and may influence metastasis of cancer.

关键词： β-紫罗酮 SGC-7901细胞细胞增殖基质金属蛋白酶逆转录聚合酶链反应肿瘤细胞

Apoptosis of human gastric adenocarcinoma cells induced by β-ionone

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World Journal of Gastroenterology 2004年第3期10卷 348-351页

作者： jia-RenLiu 3ing-QingChen Bao-fengyang Hong-WeiDong Chang-HaoSun Qiwang GuoSong You-Qiangsong PublicHealthCollege HarbinMedicalUniversityHarbin150001HeilongjiangProvinceChina DepartmentofPharmacology HarbinMedicalUniversityHarbin150086HeilongjiangProvinceChina DepartmentofBiochemistryandTheGenomeResearchCenter TheUniversityofHongKongHongKongChina

AIM:To investigate the effect of β-ionone on the growth and apoptosis of gastric adenocarcinoma cell line ***: Using M-IT, fluorescence dye (Hoechst-33258),transmission electron microscopy and the TUNEL assay,we examined growth and apoptosis of SGC-7901 cells treated with β-ionone at various concentrations (i.e. 25, 50, 100 and 200μmol/L) for 24h,***:The growth of SGC-7901 cells was inhibited by β-ionone. Seven days after treatment with β-ionone at four concentrations, the inhibition rates were 12.04%, 30.59%,78.25% and 94.15%, respectively. The IC50 value of β-ionone for SGC-7901 cells was estimated to be 89μmol/*** apoptotic morphology was demonstrated in SGC-7901 cells treated with β-ionone by Hoechst-33258 staining and electron microscopy. Apoptosis was also shown in β-iononetreated SGC-7901 cells by the TUNEL ***:β-ionone can inhibit cell proliferation and induce apoptosis of SGC-7901 ***, the mechanism needs to be further investigated.

关键词： β-紫罗酮胃腺癌肿瘤细胞细胞凋亡 TUNEL法发射电子显微镜肿瘤抑制

Theoretical Investigation on the Mechanisms and Dynamics of the Reaction CHF2OCF2CHFCl + Cl

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Theoretical Investigation on the Mechanisms and Dynamics of ...

Theoretical Investigation of Homogeneous Gaseous Reaction of 2NO2（g）+nH2O（g） +nNH3（g）→Products（n=1,2）

中国化学会第十二届全国量子化学会议

作者： fengyang Bai Xu Wang Yanqiu Sun Ziman jia Rongshun Wang Xiumei Pan Faculty of Chemistry Institute of Functional Material ChemistryNortheast Normal University

The theoretical investigation on the mechanisms and dynamics of the reaction CHF2OCF2CHFCl+Cl have been studied at the B3LYP/6-311G（d,p）,BHand LYP/6-311G（d,p）,M06-2X/6-311G（d,p）and further refined by CCSD（T）,QCISD（T）methods at the three low levels,*** theoretical reaction Gibbs free energies（△Grθ,298）and reaction Enthalpies（△Hrθ,298）are also calculated at the same *** results show that the barrier energy of the reaction CHF2OCF2CHFCl+Cl→CHF2OCF2CFCl+HCl is6.8kcal/mol,lower than the 10.6 kcal/mol of the CHF2OCF2CHFCl+Cl→CF2OCF2CHFCl+*** total rate constant k=2.90×10-15cm3 molecule-1 s-1 at 296K by means of canonical variational transition state at QCISD（T）//B3LYP/6-311G（d,p）level is in good agreement with the available data（3.2×10-15cm3 molecule-1s-1）.In the range of temperature（220-2000 K）,the variational effect is almost negligible,and the total rate constant is an positive temperature *** results show that the H-abstraction from-CHFCl group is the major product in the medium and low *** three-parameter expressions（in units of cm3molecule-1s-1）for the title reaction within 220-2000 K is k（T）=1.38×10-19 T 2.57exp（-2622.95/T）.

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Theoretical Investigation of Homogeneous Gaseous Reaction of...

玉米赤霉烯酮对青年母猪子宫发育、生长激素分泌及其受体分布与表达的影响

中国化学会第十二届全国量子化学会议

作者： Xu Wang fengyang Bai Yanqiu Sun Ziman jia Rongshun Wang Xiumei Pan Faculty of Chemistry Institute of Functional Material ChemistryNortheast Normal University

The CCSD（T）//MP2/6-311G（d,p）level of theory was employed to investigate the formation mechanism of the homogeneous gaseous reaction of 2NO2（g）+n H2O（g）+n NH3（g）→Products（n=1,2）around room *** initio study indicates that the reaction may proceed through the formation of NH3·H2O（g）,NO2·NH3（g）,and NO2·H2O（g）*** complexes,HNO3·NH4ONO,HNO3·NH4NO2,and c-HONO·NH4NO3-2 can be formed by adding gaseous reactants to the NH3·H2O（g）,NO2·NH3（g）,and NO2·H2O（g）complexes,*** HNO3·NH4ONO,HNO3·NH4NO2,and c-HONO·NH4NO3-2 complexes can then be rearranged to produce c-HONO·NH4NO3,t-HONO·NH4NO3,and HNO3·t-NH4ONO complexes via a transition state,and the NH3 molecule acts as a medium,accepting and donating hydrogen atoms in the rearrangement *** results show that NH4NO2·NH4NO3 is formed as aerosol particulate matter when addition of a NO2 molecule to the（NH3）2·H2O·NO2 complex,our computational results also reveal that the presence of an addition water molecule can not only reduce the activation energy of the rearrangement process,but also stabilizing the complexes and products.

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动物营养学报 2021年第1期33卷 217-226页

作者：吴峰洋崔嘉杨新宇陈宝江河北农业大学动物科技学院保定071000 河北省牛羊胚胎技术创新中心保定071000

本试验旨在研究玉米赤霉烯酮(ZEA)对青年母猪子宫发育、生长激素(GH)分泌及其受体(GHR)分布与表达的影响。选择胎次和体重[(23.20±0.68)kg]相近的长×大二元青年母猪48头,将其随机分为4组,每组12个重复,每个重复1头。对照组(CON组)饲... 详细信息

本试验旨在研究玉米赤霉烯酮(ZEA)对青年母猪子宫发育、生长激素(GH)分泌及其受体(GHR)分布与表达的影响。选择胎次和体重[(23.20±0.68)kg]相近的长×大二元青年母猪48头,将其随机分为4组,每组12个重复,每个重复1头。对照组(CON组)饲喂基础饲粮,试验组(T1、T2、T3组)饲喂在基础饲粮中分别添加200、800、1600μg/kg ZEA的试验饲粮。预试期7 d,正试期40 d。结果表明:1)各组间血清及子宫组织中GH含量均无显著差异(P>0.05)。2)各组间子宫组织中ZEA含量均无显著差异(P>0.05)。3)各组间始重、末重、平均日增重(ADG)、平均日采食量(ADFI)及料重比(F/G)均无显著差异(P>0.05);但与CON组相比,T2组子宫指数显著升高(P0.05)。6)ZEA对GHR在青年母猪子宫中的分布与定位无明显影响,但与CON组相比,试验组GHR免疫阳性物质分布增多,免疫阳性强度增大。7)各组间子宫GHR蛋白表达量没有显著差异(P>0.05);但与CON组相比,T2组灰度值有升高的趋势(P=0.09)。综上所述,ZEA对青年母猪的生长性能以及血液和子宫中GH和ZEA的含量均无显著影响,但可通过升高GHR、JAK2和STAT3的mRNA相对表达量、增强GHR免疫阳性及升高蛋白表达量来增强GH的生物效应,使子宫发育异常,导致子宫指数出现极显著升高,子宫肌层和内膜增厚,子宫腺和毛细血管数量增多。

关键词：玉米赤霉烯酮青年母猪子宫生长发育生长激素生长激素受体

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解剖型和爪形接骨板固定肋骨骨折的疗效比较

中华急诊医学杂志 2019年第2期28卷 232-235页

作者：徐凤阳王楠任佳孟宇陈聚伍郑州大学第一附属医院急诊医学部急诊外科 450052

目的比较爪形接骨板与解剖型接骨板内固定治疗创伤性多发肋骨骨折的效果。方法回顾性分析2016年1月至2017年11月郑州大学第一附属医院急诊医学部急诊外科收治的70例创伤性肋骨骨折内固定手术患者的临床资料。根据内固定不同分为两组:爪... 详细信息

目的比较爪形接骨板与解剖型接骨板内固定治疗创伤性多发肋骨骨折的效果。方法回顾性分析2016年1月至2017年11月郑州大学第一附属医院急诊医学部急诊外科收治的70例创伤性肋骨骨折内固定手术患者的临床资料。根据内固定不同分为两组:爪形接骨板组(33例)和解剖型接骨板组(37例)。记录固定每处骨折所需平均手术时间、术中出血量、术后引流量、接骨板松动脱落、胸部疼痛、胸腔大出血等指标。应用SPSS17.0统计软件,计量资料比较采用t检验和秩和检验,计数资料比较采用χ^2检验;分析两种内固定的利弊。结果从骨折端完全暴露开始记录手术时间、比较固定每处骨折所需的平均手术时间,爪型接骨板组较解剖型接骨板组短[(11.04±1.81)分/处vs(12.30±0.47)分/处](P0.05)。爪型接骨板组术后出现2例胸部疼痛、2例胸腔大出血,均行二次手术。结论两种内固定各有利弊,爪型接骨板较廉价、塑形方便、手术时间较短,对粉碎性骨折特别适用;解剖型接骨板昂贵、但其术中出血量、术后引流量、胸腔大出血、胸部疼痛等并发症发生率低,明显减少二次手术,安全性较高。

关键词：肋骨骨折爪形接骨板解剖型接骨板内固定