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Neuropeptide cholecystokinin:a key neuromodulator for hippocampal functions

Neural Regeneration Research 2025年第7期20卷 1991-1992页

作者： fengwen huang Stephen Temitayo Bello Department of Neuroscience City University of Hong KongKowloon TongHong Kong Special Administrative RegionChina Center for Regenerative Medicine and Health Hong Kong Institute of Science&InnovationChinese Academy of SciencesHong Kong Special Administrative RegionChina

Spatial memory is crucial for survival within external surroundings and wild *** hippocampus,a critical hub for spatial learning and memory formation,has received extensive investigations on how neuromodulators shape its functions(Teixeira et al.,2018;Zhang et al.,2024).However,the landscape of neuromodulations in the hippocampal system remains poorly understood because most studies focus on classical monoamine neuromodulators,such as acetylcholine,serotonin,dopamine,and *** neuropeptides,comprising the most abundant neuromodulators in the central nervous system,play a pivotal role in neural information processing in the hippocampal ***(CCK),one of the most abundant neuropeptides,has been implicated in regulating various physiological and neurobiological statuses(Chen et al.,2019).CCK-A receptor(CCK-AR)and CCK-B receptors(CCK-BR)are two key receptors mediating the biological functions of CCK,both of which belong to class-A sevenfold transmembrane G protein-coupled receptors(Nishimura et al.,2015).CCK-AR preferentially reacts to sulfated CCK,whereas CCK-BR binds both CCK and gastrin with similar affinities(Ding et al.,2022).The expression patterns of CCK-AR and CCK-BR are distinct,implying that CCK has various functions in target *** instance,CCK-AR is widely expressed in the GI and brain subregions and is hence implicated in the control of digestive function and satiety ***,CCK-BR is abundantly and widely distributed in the central nervous system,which majorly regulates anxiety,learning,and memory(Ding et al.,2022).However,the roles of endogenous CCK and CCK receptors in regulating hippocampal function at electrophysiological and behavioral levels have received less attention.

关键词： abundant functions modulator

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Non-linear Analysis in High-frequency Financial Time Series

Non-linear Analysis in High-frequency Financial Time Series

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The Sixth International Conference on Information and Management Sciences

作者： Jiang Aiping~1 huang fengwen~2 (Deparment of Mathematics Tongji University 2.Urban Management College of Shanghai)

＜正＞A new methodology based on state space reconstruction techniques has been developed for financial time series analysis,t+1 temporal trend can be forecasted using 0-t high-frequency data by state space reconstruction and divergence *** this paper,we forecast the t+1 temporal of Shanghai stock market composite index based on 5- minute high-frequency time series and get a satisfied result.

关键词： state space reconstruction divergence calculation without transaction cost forecasting

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臂丛神经阻滞联合肩胛上神经阻滞在肩关节镜手术中的应用

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北京医学 2018年第6期40卷 536-538,542页

作者：廖春英黄凤文北京市怀柔区中医医院麻醉科 101400

目的观察臂丛神经阻滞联合肩胛上神经阻滞在肩关节镜手术中的麻醉效果。方法选择ASAⅠ~Ⅱ级,择期行肩关节镜手术的患者30例,随机分为2组,每组15例。试验组采用臂丛神经阻滞(高位肌间沟入路)联合肩胛上神经阻滞的麻醉方式,对照组采用单... 详细信息

目的观察臂丛神经阻滞联合肩胛上神经阻滞在肩关节镜手术中的麻醉效果。方法选择ASAⅠ~Ⅱ级,择期行肩关节镜手术的患者30例,随机分为2组,每组15例。试验组采用臂丛神经阻滞(高位肌间沟入路)联合肩胛上神经阻滞的麻醉方式,对照组采用单纯臂丛神经阻滞(高位肌间沟入路)的麻醉方式,记录术前(T_0)、切皮(T_1)、关节镜器械进入关节腔(T_2)、缝皮(T_3)时的MAP、HR和VAS评分,比较2组患者的麻醉效果及膈神经、喉返神经阻滞、局麻药中毒、气胸及霍纳综合征等不良反应发生率。结果麻醉效果Ⅰ级试验组13例,对照组2例,试验组麻醉效果Ⅰ级比例明显高于对照组,差异有统计学意义(P0.01);2组患者不良反应发生率差异无统计学意义(P>0.05)。结论臂丛神经阻滞联合肩胛上神经阻滞在肩关节镜手术中安全,麻醉效果好,具有临床应用价值。

关键词：肩胛上神经阻滞臂丛神经阻滞肩关节镜手术临床应用价值手术中不良反应发生率麻醉效果肌间沟入路

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我国开发股指期货风险规避策略研究

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西北农林科技大学学报（社会科学版） 2006年第1期6卷 50-54页

作者：黄凤文吴育华上海城市管理学院城市金融研究中心上海200233 天津大学管理学院天津300072

股指期货是一种新的金融衍生产品,对发展和完善我国证券市场具有重要意义。本文在详细介绍了股指期货的特点和功能的基础上,借鉴发达国家和地区股指期货推出和发展经验,结合我国证券市场实际,对开发股指期货的必要性和可行性进行探讨,... 详细信息

股指期货是一种新的金融衍生产品,对发展和完善我国证券市场具有重要意义。本文在详细介绍了股指期货的特点和功能的基础上,借鉴发达国家和地区股指期货推出和发展经验,结合我国证券市场实际,对开发股指期货的必要性和可行性进行探讨,并针对开发股指期货实施步骤、政策准备和风险规避策略等方面提出了相关建议:实施步骤及政策准备应包括法律、管理规则修改与准备、科学编制股指、渐进式开放和借鉴国外经验等几个方面;风险规避策略包括建立严密的法规与监管体系、科学合理地设计股指期货合约、完善市场运行机制、加强期货市场与股票市场的合作和壮大与完善股指期货的投资主体等七个方面。

关键词：股指期货实施步骤风险防范

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Effect Comparison on Forecasting of High-Frequency Time Series by Non-Linear Analysis

Effect Comparison on Forecasting of High-Frequency Time Seri...

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第十五届工业工程与工程管理国际会议

作者： huang fengwen~1 Zhang Bao~2 yin 1 Research Center of Finance Urban Management College of Shanghai Shanghai P.R.China 200233 2 Management School Tianjin University Tianjin P.R.China 300072

＜正＞In order to obtain the predictability of high-frequency time series,this paper develops state space reconstruction and divergence calculation techniques have been for t+1 temporal trend of stock index,state space reconstruction technique preserve certain information on original time series which describes the asymptotic behavior of *** describing the asymptotic behavior,the properties of the system will be shown better when the time t is large enough. Divergence calculation of dynamical system is used to describe the characterization of system and analyze the temporal *** divergence is locally equivalent to the trace of the Jacobian and measures the rate of the change of an infinitesimal state space volume V（t） following an orbit x（t）.In this paper,we forecast the t+1 temporal of Shanghai stock market composite index based on 5-minute high-frequency time series and get a satisfying result.

关键词： Non-linear Analysis State Space Reconstruction Divergence Calculation Transaction Cost Forecasting

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基于振动的变压器绕组松动缺陷诊断方法

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中国电力 2018年第6期51卷 83-88页

作者：周宇马宏忠黄凤文顾金平陈涛涛弓杰伟朱诗朕国网宿迁供电公司江苏宿迁223800 河海大学能源与电气学院江苏南京211100 国网泰州供电公司江苏泰州225000 宿迁阳光送变电工程有限公司江苏宿迁223800

将理论与实验相结合,对变压器绕组松动缺陷诊断方法进行研究。理论上定义了基于预紧力的变压器绕组松动缺陷特征值,该特征值与变压器绕组预紧力之间存在规律的单调区间,提出利用该关系进行缺陷诊断,该方法不受电流影响,因而适用于负荷... 详细信息

将理论与实验相结合,对变压器绕组松动缺陷诊断方法进行研究。理论上定义了基于预紧力的变压器绕组松动缺陷特征值,该特征值与变压器绕组预紧力之间存在规律的单调区间,提出利用该关系进行缺陷诊断,该方法不受电流影响,因而适用于负荷波动下的在线监测。在实验中采用应变片桥式电路测量预紧力,施加不同的预紧力进行绕组松动缺陷设置。利用锤击法测算油箱固有频率,考虑预紧力变化对油箱固有频率的影响,以不受共振影响的测点为有效测点。分析不同预紧力大小、不同电流情况下变压器有效测点信号的特征值,确定故障阈值与预警阈值,实现绕组松动缺陷诊断以及缺陷相定位。

关键词：变压器绕组松动缺陷共振特征值诊断方法

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β-Ga2O3 MOSFETs on the Si substrate fabricated by the ion-cutting process

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Science China(Physics,Mechanics & Astronomy) 2020年第7期63卷 93-96页

作者： YiBo Wang WenHui Xu TianGui You fengwen Mu HaoDong Hu Yan Liu Hao huang Tadatomo Suga GenQuan Han Xin Ou Yue Hao The State Key Discipline Laboratory of Wide Band Gap Semiconductor Technology School of MicroelectronicsXidian UniversityXi'an 710071China The State Key Laboratory of Functional Materials for Informatics Shanghai Institute of Microsystem and Information TechnologyChinese Academy of SciencesShanghai 200050China The Collaborative Research Center Meisei UniversityHino shiTokyo 191-8506Japan

β-Ga2O3 MOSFETs are demonstrated on heterogeneous Ga2O3-Al2O3-Si(GaOISi)substrate fabricated by ion-cutting ***(E)-and depletion(D)-modeβ-Ga2O3 transistors are realized on by varying the channel thickness(Tch).E-mode GaOISi transistor with a Tchof 15 nm achieves a high threshold voltage VTHof^8 *** the same T increase,GaOISi transistors demonstrate more stable ON-current IONand OFF-current IOFFperformance compared to the reported devices on bulk Ga2O3 *** on GaOISi achieve the breakdown voltage of 522 and 391 V at 25°C and 200°C,respectively.

关键词： Ga203,1MOSFET thermal conductivity heterogeneous Ga2O3-Al2O3-Si

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Randomized controlled study of a diagnosis and treatment plan for moderate coronavirus disease 2019 that integrates Traditional Chinese and Western Medicine

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Journal of Traditional Chinese Medicine 2022年第2期42卷 234-241页

作者： XIA Wenguang ZHENG Chanjuan ZHANG Jixian huang Min LI Qinglin DUAN Can LI Zhengliang FAN Cunyu ZOU Yilong XU Bo YANG fengwen LIU Qingquan Rehabilitation Department Hubei Provincial Hospital of Integrated Traditional Chinese and Western MedicineWuhan 430000China Respiratory Department Hubei Provincial Hospital of Integrated Traditional Chinese and Western MedicineWuhan 430000China Endocrinology Department Hubei P rovincial Hospital of Integrated Traditional Chinese and Western MedicineWuhan 430000China Traditional Chinese Medicine Department Tianjin University of Traditional Chinese MedicineTianjin 300000China Emergency Department Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical UniversityBeijing 100000China

OBJECTIVE:To investigate the clinical efficacy and safety of a diagnosis and treatment plan for moderate coronavirus disease 2019(COVID-19)that integrates traditional Chinese(TCM)and western ***:One hundred twenty patients with moderate COVID-19 were randomized 1∶2 to the control group(n=40)and experimental group(n=80).Both groups received conventional western medicine treatment,and the experimental group also received TCM *** a 2-week period from diagnosis,we observed the time to clinical recovery(TTCR),rate of improvement on lung computed tomography(CT)imaging,time to defervescence,cough remission time,hospital discharge rate,average hospitalization stay,modified Medical Research Council(m MRC)scale score,clinical cure rate,laboratory findings,incidence of progression to severe or critical disease,and adverse ***:Among 120 enrolled patients,108 completed the *** baseline data did not differ between the experimental and control groups(all P>0.05).After treatment,the TTCR,rate of lung CT imaging improvement,time to defervescence,cough remission time,hospital discharge rate,average hospitalization stay(among discharged patients),m MRC scale score,clinical cure rate,and rates of normal values for laboratory findings were better in the experimental group than in the control group(P0.05).CONCLUSION:The diagnosis and treatment plan integrating Chinese and western medicine showed improved clinical efficacy compared with western medicine alone for patients with moderate COVID-19 and is worthy of clinical promotion and application.

关键词： COVID-19 SARS-CoV-2 integrative medicine diagnosis and treatment plan

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New problems and countermeasures in the prevention and control of COVID-19

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Emergency and Critical Care Medicine 2021年第1期1卷 12-13页

作者： fengwen Yang Junhua Zhang Wenke Zheng Ming huang Lei Zhang Boli Zhang Evidence-Based Medicine Center Tianjin University of Traditional Chinese MedicineTianjinChina State Key Laboratory of Component-Based Chinese Medicine TianjinChina Tianjin Hospital TianjinChina

COVID-19 *** the strong leadership of the Chinese government,with timely decisions and plans,and through the concerted efforts of the entire nation,major successes were achieved in the fight against COVID-19 in less than 3 months(between January and April 2020).Although some sporadic cases and even small-scale local outbreaks occurred in some areas thereafter,they were effectively controlled in an even shorter period of time.

关键词： prevention COV leadership

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Defect evolution in GaN thin film heterogeneously integrated with CMOS-compatible Si(100) substrate by ion-cutting technology

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Science China(Information Sciences) 2023年第11期66卷 313-314页

作者： Hangning SHI Ailun YI Jiaxin DING Xudong LIU Qingcheng QIN Juemin YI Junjie HU Miao WANG Demin CAI Jianfeng WANG Ke XU fengwen MU Tadatomo SUGA René HELLER Mao WANG Shengqiang ZHOU Wenhui XU Kai huang Tiangui YOU Xin OU State Key Laboratory of Functional Materials for Informatics Shanghai Institute of Microsystem and Information Technology Chinese Academy of Sciences University of Chinese Academy of Sciences School of Materials and Chemistry University of Shanghai for Science and Technology Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences Suzhou Nanowin Science and Technology Co. Ltd. SABers Co. Ltd. Collaborative Research Center Meisei University Helmholtz-Zentrum Dresden-Rossendorf Institute of Ion Beam Physics and Materials Research College of Physics and Electronic Engineering Sichuan Normal University

Ion-cutting technology is an ingenious solution to the highquality heterogeneous integration of Ga N thin films with CMOS-compatible Si(100) substrate, which provides a platform to combine Ga N-based optoelectronics, high-frequency and high-power electronics with digital signal processing,logic computation, and control of Si(100) CMOS [1].

关键词： Gallium nitride

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