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Science China Earth Sciences 2015年第11期58卷 2015-2025页

作者： chen fengjiao FU YunFei School of Earth and Space Sciences University of Science and Technology of China State Key Laboratory of Severe Weather Chinese Academy of Meteorological Sciences

Based on 10 years precipitation data from Tropical Rainfall Measurement Mission （TRMM） Multi-satellite Precipitation Analysis （TMPA） 3B42 and the best track data from China Meteorological Administration （CMA）, the seasonal, monthly and annual contribution of tropical cyclone （TC） precipitation to the total rainfall are analyzed over the Western North Pacific （WNP） during 1998 to 2007 from May to December. The results show that：（1） TC seasonal rainfall contribution ranges from 4% in inland regions to above 40% in ocean-regions of 15°N-25°N. TCs at higher categories contribute much more to the total precipitation. （2） On monthly scale, TCs contribute 60% to the total rainfall regionally during whole TC season, which is the maximum contribution. The peak contribution of TC rainfall averaged in multi-months of the ten years occurs in August （28%） over the whole ocean impacted by TC and in December （23%） over the whole land impacted by TC, respectively. （3） On annual scale, the maximum contribution of TC precipitation to the total rainfall are in 2004 （-30%） over ocean and in 1998 （-20%） over land, respectively. （4） The contribution of TC precipitation to the total rainfall increases 6% （decreases 6%） in El Nino （La Nifia） years compared with neutral years.

关键词： tropical cyclone precipitation contribution 3B42 WNP ENSO

Major Scientific Achievements of the First China–Japan Cooperative GAME/HUBEX Experiment: A Historical Review

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Journal of Meteorological Research 2020年第4期34卷 659-674页

作者： Yihui DING Wen HU Yong HUANG fengjiao chen National Climate Center China Meteorological AdministrationBeijing 100081 Key Laboratory of Atmospheric Sciences and Satellite Remote Sensing of Anhui Province Anhui Meteorological BureauHefei 230031 Shouxian National Climatology Observatory Huaihe River Basin Typical Agro-Ecosystems Meteorology Field Experiment Station of China Meteorological AdministrationShouxian 232200

In the summers of 1998 and 1999, Chinese and Japanese scientists cooperatively conducted the first large-scale energy and water cycle experiment(WCRP/GEWEX/GAME/HUBEX: World Climate Research Program/Global Energy and Water Cycle Experiment/Asian Monsoon Experiment/Huaihe River Basin Energy and Water Cycle Experiment) in the Huaihe River basin, Anhui Province of China. The main objective of this field experiment(HUBEX)was to investigate the multiple-scale structure characteristics, life cycles, and genesis and development mechanisms of the Meiyu system in East Asia as well as the cause of related flooding disasters. It was a joint China-Japan cooperative meteorological and hydrological observation experiment. On the basis of intensive observations, scientists from the two countries conducted follow-up investigations through collating and compiling data and performing scientific analysis during the following five years. It can be concluded that the HUBEX project has yielded comprehensive and remarkable achievements. This paper introduces the major scientific results derived from this field experiment and the ensuing investigations, and reassesses their merits and shortages for the purpose of providing useful experience and proposing new research targets as well as prospects for the initiation of a new joint scientific Meiyu experiment in the middle and lower Yangtze River basin.

关键词： Meiyu Huaihe River basin energy and water cycle meteorological and hydrological observations Huaihe River Basin Energy and Water Cycle Experiment(HUBEX)/Global Energy and Water Cycle Experiment(GEWEX)/Asian Monsoon Experiment(GAME)

Comprehensive biological function analysis of lncRNAs in hepatocellular carcinoma

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Genes & Diseases 2021年第2期8卷 157-167页

作者： Dan Wang fengjiao chen Tao Zeng Qingxia Tang Bing chen Ling chen Yan Dong Xiaosong Li Department of Clinical Laboratory People’s Hospital of Rongchang DistrictChongqingRongchang 402460PR China Key Laboratory of Molecular Biology of Infectious Diseases Ministry of EducationChongqing Medical UniversityChongqing400016PR China chengdu Women’s and Children’s Central Hospital School of MedicineUniversity of Electronic Science and Technology of ChinaSichuan ProvinceChengdu611731PR China Clinical Molecular Medicine Testing Center The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016PR China

Thousands of long non-coding RNAs(lncRNAs)have been discovered in human genomes by gene chip,next-generation sequencing,and/or other methods in recent years,which represent a significant subset of the universal genes involved in a wide range of biological *** abnormal expression of lncRNAs is associated with the growth,invasion,and metastasis of various types of human cancers,including hepatocellular carcinoma(HCC),which is an aggressive,highly malignant,and invasive tumor,and a poor prognosis in *** a more in-depth understanding of lncRNA research for HCC and the emergence of new moleculartargeted therapies,the diagnosis,treatment,and prognosis of HCC will be considerably ***,this review is expected to provide recommendations and directions for future lncRNA research for HCC.

关键词： ceRNAs HCC lncRNAs miRNAs ncRNAs snoRNAs

Stabilizing nickel sulfide nanoparticles with an ultrathin carbon layer for improved cycling performance in sodium ion batteries

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Nano Research 2016年第10期9卷 3162-3170页

作者： Feipeng Zhao Qiufang Gong Brian Traynor Duo Zhang Jiaojiao Li Hualin Ye fengjiao chen Na Han Yeyun Wang Xuhui Sun Yanguang Li Institute of Functional Nano & Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices Soochow University Suzhou 215123 China Departments of Physics and Chemistry Trinity College University of Dublin Dublin 2 Ireland

Nanostructured metal sulfides are potential electrode materials for sodium-ion batteries; however, they typically suffer from very poor cycling stability due to large volume changes and dissolution of discharge products. Herein we propose a rational material design strategy for sulfide-based materials to address these problems. Taking nickel sulfide （NiSx） as an example, we demonstrated that its electrochemical performance can be dramatically improved by confining the NiSx nanoparticles in a percolating conductive carbon nanotube network, and stabilizing them with an ultrathin carbon coating layer. The carbon layer serves as a physical barrier to alleviate the effects of both the volume change and dissolution of active materials. The hybrid material exhibited a large reversible specific capacity of 〉500 mAh/g and excellent cycling stability over 200 cycles. Given the traditionally problematic nature of NiSx as a battery anode material, we believe that the observed high performance reported here reflects the effectiveness of our material design strategy.

关键词： metal sulfides sodium-ion batteries composite carbon coating layer cycling stability

Relationship between Extreme Precipitation and Temperature in Two Different Regions:The Tibetan Plateau and Middle–East China

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Journal of Meteorological Research 2019年第5期33卷 870-884页

作者： Rui WANG Tao XIAN Mengxiao WANG fengjiao chen Yuanjian YANG Xiangdong ZHANG Rui LI Lei ZHONG Chun ZHAO Yunfei FU School of Earth and Space Sciences University of Science and Technology of ChinaHefei 230026China Anhui Meteorological Information Center Anhui Institute of Meteorological SciencesHefei230061China School of Atmospheric physics Nanjing University of Information Science&TechnologyNanjing 210044China International Arctic Research Center and Department of Atmospheric Sciences University of Alaska FairbanksAK 99775USA

The change of extreme precipitation with temperature has regional characteristics in the context of global *** this study, radiosonde data, co-located rain gauge(RG) observations, and Tropical Rainfall Measuring Mission(TRMM) precipitation radar(PR) products are used to explore the relationship between extreme precipitation intensity and near-surface temperature in Middle–East China(MEC) and the eastern Tibetan Plateau(TP) during1998–2012. The results show that extreme precipitation intensity increases with increasing temperature at an approximate Clausius–Clapeyron(C–C) rate(i.e., water vapor increases by 7% as temperature increases by 1°C based on the C–C equation) in MEC and TP, but the rate of increase is larger in TP than in MEC. This is probably because TP(MEC) is featured with deep convective(stratiform) precipitation, which releases more(less) latent heat and strengthens the convection intensity on a shorter(longer) timescale. It is also found that when temperature is higher than 25°C(15°C) in MEC(TP), the extreme precipitation intensity decreases with rise of temperature, suggesting that the precipitation intensity does not always increase with warming. In this case, the limited atmospheric humidity and precipitable water could be the primary factors for the decrease in extreme precipitation intensity at higher temperatures.

关键词： extreme precipitation Clausius–Clapeyron(C–C) rate temperature humidity precipitable water

Climatological Characteristics of Summer Precipitation over East Asia Measured by TRMM PR:A Review

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Journal of Meteorological Research 2017年第1期31卷 142-159页

作者： Yunfei FU Xiao PAN Yuanjian YANG fengjiao chen Peng LIU School of Earth and Space Sciences University of Science and Technology of China Hefei 230026 Key Laboratory of Atmospheric Sciences and Satellite Remote Sensing of Anhui Province Anhui Institute of Meteorological Sciences Hefei 230031 Anhui Meteorological Information Centre Hefei 230031 Anhui Academy for Environmental Science Research Hefei 230071

Precipitation is an important indicator of climate change and a critical process in the hydrological cycle, on both the global and regional scales. Methods of precipitation observation and associated analyses are of strategic importance in global climate change research. As the first space-based radar, the Tropical Rainfall Measuring Mission （TRMM） Precipitation Radar （PR） has been in operation for almost 17 years and has acquired a huge amount of cloud and pre- cipitation data that provide a distinctive view to help expose the nature of cloud and precipitation in the tropics and subtropics. In this paper we review recent advances in summer East Asian precipitation climatology studies based on long-term TRMM PR measurements in the following three aspects：（1） the three-dimensional structure of precipita- tion, （2） the diurnal variation of precipitation, and （3） the recent precipitation trend. Additionally, some importantprospects regarding satellite remote sensing of precipitation and its application in the near future are discussed.

关键词： East Asia TRMM PR precipitation structure diurnal variation of precipitation precipitation trend

A Study on Precipitation Products with High Resolution in Anhui Province Based on Thin Plate Smoothing Spline

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Meteorological and Environmental Research 2019年第3期10卷 41-47页

作者： Li Jun Wen Huayang chen fengjiao Division of Forecasting and Network China Meteorological AdministrationBeijing 100081China Anhui Meteorological Information Center Hefei 230031China

In order to achieve refined precipitation grid data with high accuracy and high spatial resolution,hourly precipitation grid dataset with 1 km spatial resolution in Anhui Province from May to September (in the rainy season) in 2016 and from August 2017 to July 2018 was established based on thin plate smoothing spline (TPS),which meets the needs of climate change research and meteorological disaster risk *** interpolation errors were then *** grid precipitation product obtained based on thin plate smoothing spline,CLDAS-FAST and CLDAS-FRT were *** results show that the interpolated values of hourly precipitation by thin plate smoothing spline are close to the observed values in the rainy season of *** errors are generally below 0.9 mm/***,the errors of precipitation in the mountainous areas of eastern Huaibei and western Anhui are above 1.2 mm/*** monthly scale,the errors in June and July are the largest,and the proportion of absolute values of the errors ≥2 mm/h is up to 2.0% in June and 2.2% in *** errors in September are the smallest,and the proportion of absolute values of the errors ≥2 mm/h is only 0.6%.The root mean square (RMSE) is only 0.37 mm/h,and the correlation coefficient (COR) is *** interpolation accuracy of CLDAS-FRT is the highest,with the smallest RMSE (0.65 mm/h) and mean error ( ME =0.01 mm/h),and the largest COR (0.81).The accuracy of the precipitation product obtained by thin plate smoothing spline interpolation is close to that of *** RMSE is up to 0.80 mm/h,and its ME is only -0.01 mm/*** COR is 0.73,but its bias (BIAS) is up to 1.06 mm/h.

关键词： Precipitation High resolution Thin plate smoothing spline

A Study on Spatial Interpolation of Temperature in Anhui Province Based on ANUSPLIN

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Meteorological and Environmental Research 2019年第2期10卷 51-55,60页

作者： Wen Huayang chen fengjiao Li Jun Qiu Kangjun Wang Gen Anhui Meteorological Information Center Division of Forecasting and Network China Meteorological Administration

To achieve refined temperature grid data with high accuracy and high spatial resolution,hourly temperature grid dataset with spatial resolution of 1 km in Anhui Province from January to December in 2016 was established using the ANUSPLIN thin plate spline algorithm,which meets the needs of climate change research and meteorological disaster risk assessment. And the interpolation error was analyzed. The results show that the interpolated values of hourly temperature by ANUSPLIN are close to the observed values in 2016. The error is generally below 1. 5 ℃,and the root mean square error is 0. 937 6 ℃. On monthly scale,the interpolated values of hourly temperature by ANUSPLIN are also close to the observed *** October,November,June and May,the interpolation accuracy is the highest,and the proportion of absolute error of hourly temperature lower than 2 ℃ is up to 99%,97. 4%,98. 1% and 97. 4% respectively. In February,March,August and December,the interpolation accuracy is the lowest,and the proportion of absolute error higher than 2 ℃ is 8. 1%,5. 3%,4. 1% and 4. 2% respectively. Due to the effect of complex topography in Anhui,the interpolation accuracy is the lowest in the mountainous areas of southern and western Anhui,and the interpolation error in these regions even exceeds 1. 5 ℃ annually and 1. 8 ℃ monthly.

关键词： Temperature Interpolation ANUSPLIN Thin plate smoothing spline

Generation of B Cell-Deficient Pigs by Highly Efficient CRISPR/Cas9-Mediated Gene Targeting

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Journal of Genetics and Genomics 2015年第8期42卷 437-444页

作者： fengjiao chen Ying Wang Yilin Yuan Wei Zhang Zijian Ren Yong Jin Xiaorui Liu Qiang Xiong Qin chen Manling Zhang Xiaokang Li Lihua Zhao Ze Li Zhaoqiang Wu Yanfei Zhang Feifei Hu Juan Huang Rongfeng Li Yifan Dai State Key Laboratory of Reproductive Medicine and Jiangsu Key Laboratory of Xenotransplantation Nanjing Medical University

Generating B cell-deficient mutant is the first step to produce human antibody repertoires in large animal models. In this study, we applied the clustered regularly interspaced short palindromic repeat （CRISPR）/CRISPR-associated （Cas） system to target the JH region of the pig IgM heavy chain gene which is crucial for B cell development and differentiation. Transfection of IgM-targeting Cas9 plasmid in primary porcine fetal fibroblasts （PFFs） enabled inducing gene knock out （KO） in up to 53.3% of colonies analyzed, a quarter of which harbored biallelic modification, which was much higher than that of the traditional homologous recombination （HR）. With the aid of somatic cell nuclear transfer （SCNT） technology, three piglets with the biallelic lgM heavy chain gene mutation were produced. The piglets showed no antibody-producing B cells which indicated that the biallelic mutation of the lgM heavy chain gene effectively knocked out the function of the IgM and resulted in a B cell-deficient phenotype. Our study suggests that the CRISPR/Cas9 system combined with SCNT technology is an efficient genome-editing approach in pigs.

关键词： CRISPR/Cas9 system lgM heavy chain Pig genome editing B cell-deficiency Somatic cell nuclear transfer

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杨村煤矿4S安全文化模式

中国煤炭 2005年第6期31卷 69-70页

作者：陈峰教兖矿集团杨村煤矿山东省兖州市272118

介绍了杨村煤矿4S安全文化的内涵及全力打造4S安全文化模式,建设“本安型”矿井的实践经验。

关键词：文化模式杨村煤矿安全文化实践经验本安型