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A review: Enhanced recovery of natural gas hydrate reservoirs

Chinese Journal of Chemical Engineering 2019年第9期27卷 2062-2073页

作者： Fengguang Li Qing Yuan Tianduo li Zhi li Changyu Sun Guangjin Chen Shandong Provincial Key Laboratory of Molecular Engineering Qilu University of Technology(Shandong Academy of Science)Jinan 250653China School of Chemistry and Chemical Engineering Liaocheng UniversityLiaocheng 252059China State Key Laboratory of Heavy Oil Processing China University of Petroleum Beijing 102249China

Natural gas hydrate(NGH)is a highly efficient and clean energy,with huge reserves and widespread distribution in permafrost and marine areas.Researches all over the world are committed to developing an effective exploring technology for NGH reservoirs.In this paper,four conventional in-situ hydrate production methods,such as depressurization,thermal stimulation,inhibitor injection and CO2 replacement,are briefly introduced.Due to the limitations of each method,there has been no significantly breakthrough in hydrate exploring technology.Inspired by the development of unconventional oil and gas fields,researchers have put forward some new hydrate production methods.We summarize the enhanced hydrate exploiting methods,such as CO2/N2–CH4 replacement,CO2/H2–CH4 replacement,hydraulic fracturing treatment,and solid exploration;and potential hydrate mining techniques,such as self-generating heat fluid injection,geothermal stimulation,the well pattern optimization of hydrate exploring.The importance of reservoir stimulation technology for hydrate exploitation is emphasized,and it is believed that hydrate reservoir modification technology is a key to open hydrate resources exploitation,and the major challenges in the process of hydrate exploitation are pointed out.The combination of multiple hydrate exploring technologies and their complementary advantages will be the development trend in the future so as to promote the process of hydrate industrialization.

关键词： Hydrate Exploration/exploitation Recovery Production Stimulation technology

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Microbial aerosol particles in four seasons of sanitary landfill site:Molecular approaches,traceability and risk assessment

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Journal of Environmental Sciences 2021年第10期33卷 120-133页

作者： lin li Jiawei Ma Kaixiong Yang fengguang Chai Junxin liu Xuesong Guo State Key Laboratory of Environmental Aquatic Chemistry Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China National Engineering Laboratory for VOCs Pollution Control Material&Technology University of Chinese Academy of SciencesBeijing 101408China Pilot National Laboratory for Marine Science and Technology Qingdao 266237China University of Chinese Academy of Sciences Beijing 100049China

Landfill sites are regarded as prominent sources of bioaerosols for the surrounding atmosphere.The present study focused on the emission of airborne bacteria and fungi in four seasons of a sanitary landfill site.The main species found in bioaerosols were assayed using high-throughput sequencing.The Source Tracker method was utilized to identify the sources of the bioaerosols present at the boundary of the landfill site.Furthermore,the health consequences of the exposure to bioaerosols were evaluated based on the average daily dose rates.Results showed that the concentrations of airborne bacteria in the operation area(OPA)and the leakage treatment area(LTA)were in the range of(4684±477)–(10883±1395)CFU/m^(3) and(3179±453)–(9051±738)CFU/m^(3),respectively.The average emission levels of fungal aerosols were 4026 CFU/m^(3) for OPA and 1295 CFU/m^(3) for LTA.The landfill site received the maximum bioaerosol load during summer and the minimum during winter.Approximately 41.39%–86.24%of the airborne bacteria had a particle size of 1.1 to 4.7μm,whereas 48.27%–66.45%of the airborne fungi had a particle size of more than 4.7μm.Bacillus sp.,Brevibacillus sp.,and Paenibacillus sp.were abundant in the bacterial population,whereas Penicillium sp.and Aspergillus sp.dominated the fungal population.Bioaerosols released from the working area and treatment of leachate were the two main sources that emerged in the surrounding air of the landfill site boundary.The exposure risks during summer and autumn were higher than those in spring and winter.

关键词： Microbial aerosols Particle size distribution Factors Exposure risk Landfill site

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Effect of process parameters on the recrystallization and size control of puerarin using the supercritical fluid antisolvent process

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Asian Journal of Pharmaceutical Sciences 2016年第2期11卷 281-291页

作者： Ying li Yibin Yu Hanbing Wang fengguang Zhao Department of Pharmacy School of MedicineShenzhen UniversityShenzhenChina Division of life Science&Health Graduate School at ShenzhenTsinghua UniversityShenzhenChina School of Pharmacy Shenyang Pharmaceutical UniversityShenyangChina Research Institute of Joincare Pharmaceutical Group Industry Co.Ltd ShenzhenChina

The purpose of this study was to investigate the influence of the supercritical CO2 processing on the particle size and morphology of puerarin crystals. The process parameters included solvents, temperature, pressures, antisolvent times, addition volumes, antisolvent addition rates and solute concentrations. After being processed, the dramatic reduction of the dimensions and the change of the crystal shape were noticed. Decreasing the antisolvent addition rate, increasing the temperature and the addition volume below 50 ml led to a decrease in size. The new crystal of puerarin generated at the optimal conditions was 30.34 μm.The solvent of methanol and the concentration of 60 mg/ml were found to determine the type and degree of crystallinity of particles. These results showed that this process has the potential to produce a drug recrystallization product with newly generated crystal forms and the size of drug particles could be controlled through the tuning of various experimental conditions.

关键词： Puerarin Microparticles Supercritical fluid GAS Crystallization Particle size

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Tuned Morphological Electrospun Hydroxyapatite Nanofibers via pH

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Journal of Bionic Engineering 2012年第4期9卷 478-483页

作者： Xiaofeng Song Fengguang Ling Haotian li Zhantuan Gao Xuesi Chen School of Chemical Engineering Changchun University of Technology Changchun 130012 P. R. China Key Laboratory of Polymer Ecomaterials Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 P. R. China

The concept of biocompatible, osteoconductive and noninflammatory material mimicking the structure of natural bone has generated a considerable interest in recent decades. Hydroxyapatite （HA） is an important bionic material that is used for bone grafting in osseous defects and drug carriers. HA with various morphologies and surface properties have been widely investi- gated. In this paper, HA nanofibers are produced through a combination of electrospinning and sol-gel technique. The mor- phologies, composition and structure are investigated by Scanning Electron Microscopy （SEM）, Thermogravimetic Analysis （TGA）, Fourier Transform Infrared （FTIR）, X-ray Diffraction （XRD） patterns, Transmission Electron Microscopy （TEM）. The results show that HA nanofibers are even and well-crystallized, and pH is crucial for producing HA nanofibers. With the change of pH from 4 to 9, nanofibers grow densely along （210） plane and become compact while surface area, pore volume and pore size decrease correspondingly. The synthesized HA nanofibers are nontoxic and safe. Zn can be also incorporated into HA nanofibers, which will endow them with more perfect function.

关键词： electrospinning sol hydroxyapatite pH

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基于认知象似及语用取效的汉语网络空间女性指示语研究

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西安外国语大学学报 2023年第1期31卷 9-14页

作者：张黎刘风光大连外国语大学公共外语教研部国家语委中国东北亚语言研究中心(大连外国语大学) 大连外国语大学英语学院大连外国语大学中国东北亚语言研究中心

本研究在梳理女性指示语研究的基础上,采用认知语用学理论,以汉语网络空间话语为语料,探讨象似性和取效行为对女性指示语分析的阐释力,旨在拓宽女性指示语解读的维度。研究发现:汉语网络空间女性指示语具有话题象似性、标记象似性、距... 详细信息

本研究在梳理女性指示语研究的基础上,采用认知语用学理论,以汉语网络空间话语为语料,探讨象似性和取效行为对女性指示语分析的阐释力,旨在拓宽女性指示语解读的维度。研究发现:汉语网络空间女性指示语具有话题象似性、标记象似性、距离象似性和隐喻象似性特征,以此通过网络语境信息、不同个体认知、社会传统观念等产生形义契合效果、交际反应效果和社会认知效果,使多元话语接收者对中国女性形象、社会身份等产生正向和负向的多元认知。本研究为揭示汉语网络空间女性指示语的认知语用功能提供有益参考。

关键词：网络空间女性指示语认知象似性取效行为

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选煤厂浮选精煤脱水工艺改造及效果评价

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当代化工研究 2022年第11期 160-162页

作者：李风光山西焦煤西山煤电东曲选煤厂山西030200

在选煤厂的现代化建设和发展中,质量管理作为重要的环节,是保证选煤厂生产质量的关键所在,一直以来,选煤厂的质量管理与控制的难点都是以浮选精煤脱水为主,由于其中含有大量的起泡剂等物质,导致了浮选精煤在压滤脱水和消泡中难度较大,... 详细信息

在选煤厂的现代化建设和发展中,质量管理作为重要的环节,是保证选煤厂生产质量的关键所在,一直以来,选煤厂的质量管理与控制的难点都是以浮选精煤脱水为主,由于其中含有大量的起泡剂等物质,导致了浮选精煤在压滤脱水和消泡中难度较大,这对最终的产品生产质量、生产效率形成了直接的干扰,对于选煤厂的经营成本同样造成了负面的制约。本文对选煤厂浮选精煤脱水工艺技术进行了对比分析,以李村矿井的选煤厂为例,分析了该选煤厂浮选精煤脱水工艺的改造方案,提出了选煤厂浮选精煤脱水工艺的要点,进行了选煤厂浮选精煤脱水工艺改造效果的评价。

关键词：选煤厂浮选精煤脱水工艺改造效果

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工艺参数对H13钢电弧增材制造成形品质的影响

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特种铸造及有色合金 2022年第5期42卷 642-646页

作者：姜淑馨李峰光湖北汽车工业学院材料科学与工程学院

为确定H13钢丝材电弧增材制造单道单层成形的最佳工艺参数,在调质处理后的H13钢基板上,选取沉积电流为80~240 A,沉积速度为2~6mm/s;保护气体分别为(体积分数)5%的O_(2)+95%的Ar、10%的CO_(2)+90%的Ar以及20%的CO_(2)+80%的Ar等3种混合气... 详细信息

为确定H13钢丝材电弧增材制造单道单层成形的最佳工艺参数,在调质处理后的H13钢基板上,选取沉积电流为80~240 A,沉积速度为2~6mm/s;保护气体分别为(体积分数)5%的O_(2)+95%的Ar、10%的CO_(2)+90%的Ar以及20%的CO_(2)+80%的Ar等3种混合气体,通过余高系数和成形系数两个评价指标分析工艺参数对单道单层沉积层成形的影响。结果表明,余高系数和成形系数随着沉积电流的增大而降低,在120A和6mm/s的条件下余高系数最大,为3.79;在240A和6mm/s的条件下余高系数最小,为2.11。在80A和2mm/s的条件下成形系数最大,为8.56;在200A和6mm/s条件下成形系数最小,为3.42。沉积电流为120A、沉积速度为4mm/s、用20%的CO_(2)+80%的Ar混合气体保护时,得到品质优良的成形件。

关键词：电弧增材制造丝材余高系数成形系数

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High level of phosphorylated ataxia-telangiectasia mutated faciliitate F-actin dynamics and metastasis in lung cancer

High level of phosphorylated ataxia-telangiectasia mutated f...

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第十二届全国免疫学学术大会

作者： Shi Yuanyuan li Qing Gao fengguang Fujian province Xiamen cityXindian townXiamen university

Background:Previous studies showed that tumor associated pro-inflammatory cytokines shuch as IL-6,TNF-alpha activate the phosphorylation of ataxia-telangiectasis mutated(ATM) and promote lung cancer metastasis.Except for EMT and MMPs activaties,F-actin remodeling is another key factor contributes to metastasis.But,until now,the exact role of F-actin remodeling in inflammation-promoted metastasis is still unclear.Methods:In the present study,the level of phosphorylated ATM was regulated by siRNA silencing or pro-inflammatory cytokines treatment and the dynamics of F-actin,cell migration were determined by flow cytometry,confocal fluorescence microscope and cell migration assay.Results:firstly,the treatment with IL-6 or TNF-alpha obviously increased ATM phosphorylation and F-actin dynamics in lung cancer cells;secondly,the silencing of ATM not only inhibited F-actin remodeling but also decreased the abilities of migration in lung cancer cells;importantly,the activation of CRMP2,which is a important regulator of F-actin remodeling,was down-regulated by the inhibition of ATM activation;interestingly,inflammation-associated ROS contributed to ATM phosphorylation regulating F-actin dynamics and metastasis.Conclusion:Theses findings demonstrate that inflammation promote lung cancer metastasis by ROS associated ATM phosphorylation regulating F-actin dynamic and CRMP2 activation,indicating that ATM and CRMP2 are promising potential therapeutic target molecules for inflammation-associated lung cancer metastasis.

关键词： Ataxia-telangiectasis mutated F-actin inflammation metastasis CRMP2

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母线差动保护电流互感器断线处理逻辑

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电力系统自动化 2023年第14期47卷 167-173页

作者：王风光杜兴伟李力吕航丁杰南京南瑞继保电气有限公司江苏省南京市211102 智能电网保护和运行控制国家重点实验室江苏省南京市211106 国网河南省电力公司河南省郑州市450018

根据电流互感器(CT)断线对于母线差动保护的影响程度,分为支路CT断线和母联CT断线。首先,介绍了当前母线差动保护对于CT断线的处理逻辑,指出了当前逻辑存在的准确性不高、快速性不足的问题。然后,分析了母线接地故障与CT断线特征的差异... 详细信息

根据电流互感器(CT)断线对于母线差动保护的影响程度,分为支路CT断线和母联CT断线。首先,介绍了当前母线差动保护对于CT断线的处理逻辑,指出了当前逻辑存在的准确性不高、快速性不足的问题。然后,分析了母线接地故障与CT断线特征的差异,提出了包含故障识别逻辑、CT断线支路选线逻辑和故障后跳闸逻辑3个部分的支路CT断线改进处理逻辑,并引入母联双CT电流构建母联死区差动元件,提出了综合利用大差差动电流、小差差动电流和母联死区差动电流的母联CT断线的改进处理逻辑。最后,基于实时数字仿真系统试验结果,证明了改进后的逻辑能够快速准确地选择断线CT,避免差动保护在重负荷支路CT断线时误动和母线区内高阻接地故障时拒动,在发生母联CT断线时最大限度地维持了差动保护的速动性。

关键词：差动保护电流互感器(CT)断线死区差动元件高阻接地故障

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高炉铜冷却壁的应用及研究现状

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特种铸造及有色合金 2017年第6期37卷 606-610页

作者：郭睿李峰光湖北汽车工业学院材料科学与工程学院北京科技大学冶金与生态工程学院

针对目前炼铁高炉大型化、长寿化的发展趋势,从铜冷却壁应用历史及优势、铜冷却壁加工制造工艺及其在国内外的应用现状等方面对其进行了阐述。同时,对近年来铜冷却壁失效事故进行了总结分析,并对同材质内微量元素、铜材"氢病"现象、铜... 详细信息

针对目前炼铁高炉大型化、长寿化的发展趋势,从铜冷却壁应用历史及优势、铜冷却壁加工制造工艺及其在国内外的应用现状等方面对其进行了阐述。同时,对近年来铜冷却壁失效事故进行了总结分析,并对同材质内微量元素、铜材"氢病"现象、铜冷却壁挂渣稳定性等影响其寿命的因素进行了讨论,指出了铜冷却壁应用中存在的问题,并提出了发展方向。

关键词：铜冷却壁高炉氢病传热模型

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