检索结果-南通市图书馆

改进U2-Net的激光条纹中心线高精度提取

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

光电子·激光 2025年第1期36卷 61-68页

作者：陈新禹孙晓雨孙延鹏沈阳航空航天大学人工智能学院沈阳航空航天大学电子信息工程学院

针对复杂环境下激光条纹中心线提取算法稳定性差、精度低等问题，提出一种基于改进U2-Net的中心线提取新方法。首先，在U2-Net网络中加入TSA（transformer-self-attention）、TCA（transformer-cross-attention）模块以提高模型的特征... 详细信息

针对复杂环境下激光条纹中心线提取算法稳定性差、精度低等问题，提出一种基于改进U2-Net的中心线提取新方法。首先，在U2-Net网络中加入TSA（transformer-self-attention）、TCA（transformer-cross-attention）模块以提高模型的特征提取能力，实现精准像素级分割，有效去除图像中的噪声、毛刺，为后续中心线提取提供高质量的图像源；其次，根据使用场景特点，对传统Steger方法进行改进，完成激光条纹中心线高精度提取；最后，采用信度评价机制对光条中心点进行精度分析。实验结果表明，本文提出的改进U2-Net相较其他主流语义分割网络具有更高的提取精度、更好的抗噪声性能，在此基础上提取的像素中心点的信度值更高，达到传统Steger算法的1.9倍，满足高精度工业测量的需求。

关键词：线结构光语义分割光条中心提取信度评价

Nanoparticles for the treatment of spinal cord injury

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第6期20卷 1665-1680页

作者： Qiwei Yang Di Lu Jiuping Wu Fuming Liang Huayi Wang Junjie Yang Ganggang Zhang Chen Wang Yanlian Yang Ling Zhu Xinzhi sun Department of Orthopedic Surgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina CAS Key Laboratory of Standardization and Measurement for Nanotechnology CAS Key Laboratory for Biomedical Effects of Nanomaterials and NanosafetyCAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijingChina University of Chinese Academy of Sciences BeijingChina Department of Neurosurgery The First Affiliated Hospital of Chongqing Medical UniversityChongqingChina

Spinal cord injuries lead to significant loss of motor, sensory, and autonomic functions, presenting major challenges in neural regeneration. Achieving effective therapeutic concentrations at injury sites has been a slow process, partly due to the difficulty of delivering drugs effectively. Nanoparticles, with their targeted delivery capabilities, biocompatibility, and enhanced bioavailability over conventional drugs, are garnering attention for spinal cord injury treatment. This review explores the current mechanisms and shortcomings of existing treatments, highlighting the benefits and progress of nanoparticle-based approaches. We detail nanoparticle delivery methods for spinal cord injury, including local and intravenous injections, oral delivery, and biomaterial-assisted implantation, alongside strategies such as drug loading and surface modification. The discussion extends to how nanoparticles aid in reducing oxidative stress, dampening inflammation, fostering neural regeneration, and promoting angiogenesis. We summarize the use of various types of nanoparticles for treating spinal cord injuries, including metallic, polymeric, protein-based, inorganic non-metallic, and lipid nanoparticles. We also discuss the challenges faced, such as biosafety, effectiveness in humans, precise dosage control, standardization of production and characterization, immune responses, and targeted delivery in vivo. Additionally, we explore future directions, such as improving biosafety, standardizing manufacturing and characterization processes, and advancing human trials. Nanoparticles have shown considerable progress in targeted delivery and enhancing treatment efficacy for spinal cord injuries, presenting significant potential for clinical use and drug development.

关键词： antioxidants axon regeneration biocompatible materials drug carriers nanoparticles nerve regeneration neuroinflammatory diseases neuroprotection spinal cord injury stem cells

在线全文

学校读者我要写书评

暂无评论

岩浆岩中磷灰石的地球化学特征及应用

岩石学报 2025年第1期41卷 321-338页

作者：李子木令狐苗苗孙金凤孙之晗周宝全杨进辉中国科学院大学地球与行星科学学院北京100049 中国科学院大学北京燕山地球关键带国家野外科学观测研究站北京101408 中国科学院地质与地球物理研究所岩石圈演化与环境演变全国重点实验室北京100029

不同类型的岩浆岩可能来源于不同源区,经历复杂的岩浆演化过程,导致岩浆成分、温度和压力等条件发生变化。磷灰石在岩浆岩中广泛发育,可以形成于不同的岩浆环境。作为富含多种地球化学指示元素(如稀土元素、锶、锰及多种挥发分),并且对... 详细信息

不同类型的岩浆岩可能来源于不同源区,经历复杂的岩浆演化过程,导致岩浆成分、温度和压力等条件发生变化。磷灰石在岩浆岩中广泛发育,可以形成于不同的岩浆环境。作为富含多种地球化学指示元素(如稀土元素、锶、锰及多种挥发分),并且对寄主岩浆环境的变化十分敏感的副矿物,近年来被广泛应用于岩浆岩和矿床成因等研究中。了解不同类型岩石中磷灰石的矿物学和地球化学特征,是深入开展相关研究的基础。本文对GEOROC数据库及其他文献报道的岩浆岩中磷灰石稀土元素数据进行了汇总整理和归纳分析,获得了不同类型岩石中磷灰石的矿物学和稀土元素组成特征。结合多元统计分析方法,深入分析不同类型岩浆岩和花岗岩中磷灰石的稀土元素变化规律。计算结果显示,不同类型岩石中磷灰石的La元素、Eu/Eu*和Yb含量之间存在明显差异,推断综合利用La含量与(Eu/Eu^(*))/Yb值特征可以有效区分形成于不同岩浆岩的磷灰石。本文的研究表明,磷灰石在示踪岩浆源区和岩石成因方面具有独特优势,综合运用磷灰石产状、共生矿物组合、微量元素及同位素组成等分析可以为岩浆岩成因研究提供全面信息。

关键词：岩浆岩花岗岩磷灰石地球化学稀土元素岩石成因

Recent Advances in Fibrous Materials for Hydroelectricity Generation

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第2期17卷 109-133页

作者： Can Ge Duo Xu Xiao Feng Xing Yang Zheheng Song Yuhang Song Jingyu Chen Yingcun Liu Chong Gao Yong Du Zhe sun Weilin Xu Jian Fang College of Textile and Clothing Engineering Soochow UniversitySuzhou 215123People’s Republic of China National Engineering Laboratory for Modern Silk Soochow UniversitySuzhou 215123People’s Republic of China State Key Laboratory of New Textile Materials and Advanced Processing Technologies Wuhan Textile UniversityWuhan 430200People’s Republic of China Institute of Functional Nano&Soft Materials(FUNSOM) Soochow UniversitySuzhou 215123People’s Republic of China Department of Electrical and Computer Engineering University of MassachusettsAmherstMA 01003USA Department of Materials Imperial College LondonSouth Kensington CampusLondon SW72AZUK College of Textile Science and Engineering Zhejiang Sci-Tech UniversityHangzhou 310018People’s Republic of China School of Materials Science and Engineering Shanghai Institute of Technology100 Haiquan RoadShanghai 201418People’s Republic of China

Depleting fossil energy sources and conventional polluting power generation pose a threat to sustainable *** generation from ubiquitous and spontaneous phase transitions between liquid and gaseous water has been considered a promising strategy for mitigating the energy *** materials with unique flexibility,processability,multifunctionality,and practicability have been widely applied for fibrous materials-based hydroelectricity generation(FHG).In this review,the power generation mechanisms,design principles,and electricity enhancement factors of FHG are first ***,the fabrication strategies and characteristics of varied constructions including 1D fiber,1D yarn,2D fabric,2D membrane,3D fibrous framework,and 3D fibrous gel are ***,the advanced functions of FHG during water harvesting,proton dissociation,ion separation,and charge accumulation processes are analyzed in ***,the potential applications including power supply,energy storage,electrical sensor,and information expression are also ***,some existing challenges are considered and prospects for future development are sincerely proposed.

关键词： Hydroelectricity Fibrous material Streaming potential Ion diffusion

在线全文

学校读者我要写书评

暂无评论

大兴安岭森林可燃物燃烧危险性评估

东北林业大学学报 2025年第1期53卷 73-78页

作者：蔡志勇孙龙孙家宝东北林业大学哈尔滨150040 黑龙江省森林保护研究所

评估森林可燃物燃烧危险性,有助于客观认识森林火灾风险水平,从而制定相应防火和灭火措施,为开展森林火灾防治和应急管理工作提供决策依据。以黑龙江省大兴安岭林区为研究区,利用“森林火灾风险普查”3 300块标准样地调查数据,通过森林... 详细信息

评估森林可燃物燃烧危险性,有助于客观认识森林火灾风险水平,从而制定相应防火和灭火措施,为开展森林火灾防治和应急管理工作提供决策依据。以黑龙江省大兴安岭林区为研究区,利用“森林火灾风险普查”3 300块标准样地调查数据,通过森林可燃物燃烧试验,对潜在初始火强度、灌木层连续性和易燃树种密度等指标进行等级划分,量化森林可燃物的燃烧性和空间分布的连续性,判断潜在林火强度大小和易发林火种类,评估森林可燃物燃烧危险性等级。结果表明:(1)黑龙江省大兴安岭林区森林可燃物燃烧危险性等级分为4个等级,即高危险性等级、中高危险性等级、中低危险性等级、低危险性等级;(2)大兴安岭林区从北纬50°~53°30′,从低纬度到高纬度标准地森林火灾高危险性等级比例依次为0.02、0.02、0.02、0.05、0.07、0.10、0.08,低危险性等级比例依次为0.50、0.48、0.41、0.36、0.34、0.30、0.29。

关键词：森林火灾风险评估林火强度林火蔓延速度林火种类

在线全文

学校读者我要写书评

暂无评论

儿童药物难治性癫痫的遗传学及临床特征分析

中国全科医学 2025年第6期28卷 756-762页

作者：左然然孙素真河北省儿童医院神经内科河北省小儿癫痫与神经疾病重点实验室河北省石家庄市050000

背景目前儿童药物难治性癫痫(DRE)在儿童癫痫中的占比维持在30%左右,且常合并精神发育迟滞,影响患儿生活质量,因此DRE的诊疗仍然是神经病学的重大挑战。目的分析儿童DRE的遗传学特点及临床特征,为临床进行基因检测提供理论依据。方法回... 详细信息

背景目前儿童药物难治性癫痫(DRE)在儿童癫痫中的占比维持在30%左右,且常合并精神发育迟滞,影响患儿生活质量,因此DRE的诊疗仍然是神经病学的重大挑战。目的分析儿童DRE的遗传学特点及临床特征,为临床进行基因检测提供理论依据。方法回顾性选取2020—2022年于河北省儿童医院住院治疗且完善基因检测的95例DRE患儿为研究对象,根据基因检测结果分为基因突变阳性组(44例)和基因突变阴性组(51例)。收集患儿的一般资料(包括性别、发病年龄、用药情况、发热惊厥史、癫痫家族史等)、临床特征(发作类型、癫痫综合征、发育情况)、辅助检查[基因检测、视频脑电图(VEEG)检查、神经影像学检查],分析DRE的遗传病因及临床特征。结果95例DRE患儿中,男55例(57.9%)、女40例(42.1%),中位发病年龄为1.00(0.50,4.00)岁,用药数量为3(2,4)种;基因突变阳性组患儿发病年龄小于基因突变阴性组(Z=-5.322,P=0.001);两组患儿性别、发热惊厥史、癫痫家族史、用药数量比较,差异均无统计学意义(P>0.05)。38例(40.0%)的患儿确诊为癫痫综合征,其中76.3%(29/38)在新生儿或婴儿期发病;基因突变阳性组患儿癫痫综合征占比高于基因突变阴性组(χ^(2)=12.065,P=0.001)。临床发作类型多样,最常见的为2种及以上发作类型,占52.6%(50/95),其次为单一局灶性发作,占33.7%(32/95);两组DRE患儿发作类型比较,差异无统计学意义(χ^(2)=2.920,P=0.404)。57例患儿完善了发育筛查,其中43例(75.4%)在发病后出现不同程度的发育迟缓,33例(76.7%)表现为全面性发育迟缓;基因突变阳性组患儿发育迟缓占比高于基因突变阴性组(χ^(2)=5.728,P=0.017)。44例患儿检出变异基因,阳性检出率为46.3%,其中以离子通道类变异为主,SCN1A为最常见的单基因突变。90例(94.7%)患儿VEEG检查异常,以局灶性癫痫放电为主;基因突变阳性组患儿高峰失律占比高于基因突变阴性组(χ^(2)=7.425,P=0.006)。25例(26.3%)患儿存在结构性病因,其中基因突变阳性组12例,基因突变阴性组13例;两组DRE患儿结构性病因比较,差异无统计学意义(χ^(2)=0.039,P=0.844)。结论遗传因素为儿童DRE的重要病因,提示发病年龄小、发育迟缓与遗传性病因有关,应积极早期完善基因检测,有助于早期诊断DRE并精准治疗。

关键词：药物难治性癫痫儿童遗传学基因检测癫痫综合征临床特征全面性发育迟缓

在线全文

学校读者我要写书评

暂无评论

猪繁殖性能障碍的主要因素及其防治对策

动物科学与动物医学 2001年第5期18卷 39-41页

作者：刘国恒孙风波王明俊祁金栋刘基信葛俊宏王金萍刘桂春康国强天津市津南区畜牧兽医站 300270

引起猪繁殖性能障碍的主要因素有先天性的遗传因素 (染色体的畸变 ,而导致生殖系统某一器官形态缺陷 ,生理机能失常或生化紊乱 )和后天性环境因素 (疾病、营养缺乏、热应激等改变猪妊娠期间的正常胚胎发育 )。采取的主要对策是淘汰由遗... 详细信息

引起猪繁殖性能障碍的主要因素有先天性的遗传因素 (染色体的畸变 ,而导致生殖系统某一器官形态缺陷 ,生理机能失常或生化紊乱 )和后天性环境因素 (疾病、营养缺乏、热应激等改变猪妊娠期间的正常胚胎发育 )。采取的主要对策是淘汰由遗传因素造成永久性不育的个体猪只 ,控制由环境因素导致暂时性不育或低繁殖力的疫病等。

关键词：猪繁殖障碍防治

A survey of weak stability boundaries in the sun-Mars system

在线全文

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2015年第3期15卷 376-392页

作者： Jian Li Yi-Sui sun School of Astronomy and Space Science & Key Laboratory of Modern Astronomy and Astrophysics in Ministry of Education Nanjing University

We investigate the weak stability boundary （WSB） for a new primary, Mars, in the framework of the planar circular restricted 3-body problem, and also in the pla- nar bicircular restricted 4-body problem by including a perturbation due to Jupiter. For the sake of a simple stability/instability criterion, our computations have been done us- ing the equations of motion in polar coordinates. It is found that the relative size of the weakly stable sets around Mars is much larger than that of the Earth-Moon and the sun-Jupiter systems, as the mass ratio of the sun-Mars system is significantly smaller. We propose that this difference could be scaled by the Hill radius. In an enlarged view of the domain close to Mars, the geometry of the WSB has been presented for various parameters and compared to previous works. Our results also show that Jupiter＇s grav- itational force would strongly affect the Martian stable regions and should be taken into account to design a ballistic capture trajectory.

关键词： celestial mechanics

Trends of alkaline phosphatase to prealbumin ratio in patients with hepatitis B linked to hepatocellular carcinoma development

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2025年第2期31卷 42-51页

作者： Wen-Chong Zhen Jing sun Xue-Ting Bai Qian Zhang Zi-Han Li Yi-Xin Zhang Rong-Xuan Xu Wei Wu Zhi-Han Yao Chun-Wen Pu Xiao-Feng Li School of Public Health Dalian Medical UniversityDalian 116044Liaoning ProvinceChina Graduate School Dalian Medical UniversityDalian 116044Liaoning ProvinceChina Dalian Public Health Clinical Center Dalian Municipal Research Institute for Public HealthDalian 116001Liaoning ProvinceChina Department of Epidemiology and Health Statistics Dalian Medical UniversityDalian 116044Liaoning ProvinceChina

BACKGROUND Chronic hepatitis B often progresses silently toward hepatocellular carcinoma(HCC),a leading cause of mortality *** detection of HCC is crucial,yet *** To investigate the role of dynamic changes in alkaline phosphatase to prealbumin ratio(APR)in hepatitis B progression to *** Data from 4843 patients with hepatitis B(January 2015 to January 2024)were *** incidence rates in males and females were compared using the log-rank *** were evaluated using Kaplan–Meier *** Linear Mixed-Effects Model was applied to track the fluctuation of APR levels over ***,Joint Modeling of Longitudinal and Survival data was employed to investigate the temporal relationship between APR and HCC *** The incidence of HCC was higher in *** ensure the model’s normality assumption,this study applied a logarithmic transformation to APR,yielding *** levels were higher in females(t=5.26,P<0.01).A 1-unit increase in ratio correlated with a 2.005-fold higher risk of HCC in males(95%CI:1.653-2.431)and a 2.273-fold higher risk in females(95%CI:1.620-3.190).CONCLUSION Males are more prone to HCC,while females have higher APR *** no baseline APR link,rising APR indicates a higher HCC risk.

关键词： Alkaline phosphatase to prealbumin ratio Chronic hepatitis B patients Hepatocellular carcinoma Retrospective cohort study Linear Mixed-Effect Mode Joint Modelling of Longitudinal and Survival data