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Distribution of α-, β-, and γ-Phases in a Multi-flow Injection-molded Hierarchical Structure

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Chinese Journal of Polymer Science 2018年第6期36卷 765-775页

作者： Da-Shan Mi feng-yi hou Man Zhou Jie Zhang College of Polymer Science and Engineering State Key Laboratory of Polymer Materials EngineeringSichuan University

In the current work, a custom-made vibration injection molding device that can provide oscillatory pressure was utilized to create an injection-molded hierarchical structure. Growth competition among α, β, and γ phases in the injection-molded structure can be studied because of the presence of this hierarchical structure, wherein shish-kebab and spherulite layers were arranged alternately along the thickness direction. The γ crystals only existed in layers subjected to high pressure and shear stress, whereas β crystals formed between the shear layers. The change in trend of the γ fraction was similar to that of parent-to-daughter ratio. In addition, this hierarchical and alternating crystal structure can sharply increase the mechanical properties.

关键词： Shish-kebab Growth competition α Phase γ Phase β Phase

Droplet Bridging Effect in Polymer/Polymer/Filler Ternary Composites

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Chinese Journal of Polymer Science 2024年第12期42卷 1966-1975,I0010页

作者： feng-yi hou Li Peng Fei Yu Xian-Bo Huang Wei Yu Advanced Rheology Institute Department of Polymer Science and EngineeringShanghai Jiao Tong UniversityShanghai200240China National Certified Enterprise Technology Center Kingfa Science and Technology Co.Ltd.Guangzhou510663China DPI P.O.Box 9025600 AXEindhovenThe Netherlands

In particle-filled polymer composites with selective distributions of fillers in one phase,much attention has been focused on the“volume exclusion effect”in reducing the percolation threshold of filler,while the role of dispersed polymer phase acting as bridges of fillers in the particle network has largely been ***,we studied industrially important ternary composites,polypropylene(PP)/ethylene-octene copolymer(a polyolefin elastomer,POE)/talc systems,and adopted rheology to reveal the bridging behavior of POE droplets in the network of talc *** is found that talc fillers concentrate in the PP phase using the“blend first”protocol,while more talc particles are located at the interface of PP and POE phases using the“filler first”*** the POE viscosity and talc size can affect the migration of talc from the POE phase to the PP phase in the“filler first”*** linear rheology behavior indicates that besides the“volume exclusion effect”,the talc-POE hybrid network can further contribute to the reinforcement ***,the POE droplet bridging structure can facilitate the rebuilding of the hybrid network after large amplitude oscillatory shear,in contrast to the un-recoverable structures in the PP/talc binary *** correlation between rheology and selective distribution of fillers in ternary composites may provide practical guidance for processing and designing advanced polymer composites with controlled selective location of fillers.

关键词： Polypropylene Filler selective localization Rheology Bridging

Microinjection of muscimol into tuberomammillary nucleus promoting sleepδpower and suppressing wakefulnessβ2 power-induced by histamine in rats

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Microinjection of muscimol into tuberomammillary nucleus pro...

Microplastic and nanoplastic exposure and risk of diabetes mellitus

中国神经科学学会第四次会员代表大会暨第八届全国学术会议

作者： Peng XIE,Kun FAN,Min ZHANG,Yan-feng SONG,yi-Ping hou~* Department of Neuroscience and Anatomy,Histology and Embryology,School of Basic Medical Sciences,Lanzhou University,Lanzhou 730000

Objective o investigate the effect of muscimol,a potent agonist of GABA-receptor,microinjected into tubermammillary nucleus(TMn) on the sleep-wakefulness cycle,EEG power spectrum and the wake-promoting of histamine in freely *** Male SD rats were randomly divided into control group(n=7),saline group(n=7),muscimol 0.5μgroup(n=6),muscimol 0.25μgroup(n=4),HA group(n=7) and HA plus muscimol group(n=5).Animals were implanted with 4 EEG electrodes,3 EMG electrodes and a pair of stainless steel guide cannular to the adjacent of TMn for subsequent drug *** one week recovery,a 24 h basal sleep-wakefulness cycle was recorded and analyzed by Spike 2.(1) Saline and muscimol(0.25 or 0.5μg/side) were respectively microinjected into bilateral TMn at 22:00 during dark period recording from 20:00 to 8:00.(2) Saline and HA(0.125μg/side) were respectively administered into TMn at 10:00 during light period recording from 8:00 to 20:00.(3) Muscimol(0.5μg/side) was injected at 12:00 following HA administration at 10:*** EEG power spectrum was analyzed for the frequency range of 1-60 Hz includingδ(1-4 Hz),θ(4.2-8 Hz),α(8.2-12 Hz),β1(12.2-20 Hz),β2(20.2-30 Hz) andγ(30.2-60 Hz) using aFFT ***(1) Muscimol given at 0.25 and 0.5(ig/side for 12 h induced a dose-dependent decrease in wake(W,P 240 s,but that decreased in <120 *** addition,the stage transition number during 4 h from W to SWS,SWS to W,SWS to PS and PS to W were not affected respectively by muscimol.(2) HA in

关键词： sleep-wakefulness stages power spectrum tuberomammillary nucleus histamine GABAA-receptor agonist

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World Journal of Clinical Cases 2025年第3期13卷 24-29页

作者： Hui-yi Hsiao Chung-yi Nien Ruei-feng Shiu Wei-Chun Chin Tzung-Hai Yen Department of Biomedical Sciences College of MedicineChang Gung UniversityTaoyuan 33302TaiwanChina Center for Tissue Engineering Chang Gung Memorial HospitalLinkouTaoyuan 33305TaiwanChina Department of Life Sciences National Central UniversityZhongli 320317TaoyuanTaiwanChina Center of Excellence for The Oceans Taiwan Ocean UniversityKeelung 20224TaiwanChina Institute of Marine Environment and Ecology Taiwan Ocean UniversityKeelung 20224TaiwanChina Department of Chemical and Materials Engineering University of California MercedMercedCA 95343United States Department of Nephrology Clinical Poison CenterChang Gung Memorial HospitalLinkou 33305TaoyuanTaiwanChina School of Traditional Chinese Medicine College of MedicineChang Gung UniversityTaoyuan 33302TaiwanChina

The issue of plastic pollutants has become a growing *** microplastics(MPs)(particle size<5 mm)and nanoplastics(NPs)(particle size<1μm)can cause DNA damage,cytotoxicity,and oxidative stress in various *** primary known impacts of microplastic/nanoplastic are observed in the liver and respiratory system,leading to hepatotoxicity and chronic obstructive pulmonary *** research on the effects of MPs and NPs on diabetes is still in its early stages,there are potential *** editorial highlights the risk to diabetics from co-exposure to contaminants and MPs/NPs,supported by evidence from animal studies and the various chemical compositions of MPs/NPs.

关键词： Microplastics Nanoplastics Plastic pollution,Diabetes mellitus Insulin resistance

Effects of Bifidobacterium lactis BLa80 on fecal and mucosal flora and stem cell factor/c-kit signaling pathway in simulated microgravity rats

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World Journal of Gastroenterology 2025年第1期31卷 93-109页

作者： Ping Zhang ying Zhu Pu Chen Tong Zhou Zhe-yi Han Jun Xiao Jian-feng Ma Wen Ma Peng Zang ying Chen Graduate School Hebei North UniversityZhangjiakou 075000Hebei ProvinceChina Key Laboratory of Aerospace Nutrition and Food Engineering China Astronaut Research and Training CenterBeijing 100094China Department of Gastroenterology The Air Force Medical CenterBeijing 100142China Department of Blood Transfusion Air Force Medical CenterBeijing 100142China

BACKGROUND Simulated microgravity environment can lead to gastrointestinal motility *** pathogenesis of gastrointestinal motility disorders is closely related to the stem cell factor(SCF)/c-kit signaling pathway associated with intestinal flora and Cajal stromal ***,intestinal flora can also affect the regulation of SCF/c-kit signaling pathway,thus affecting the expression of Cajal stromal *** cells are the pacemakers of gastrointestinal *** To investigate the effects of Bifidobacterium lactis(***)BLa80 on the intestinal flora of rats in simulated microgravity and on the gastrointestinal motility-related SCF/c-kit *** The internationally recognized tail suspension animal model was used to simulate the microgravity environment,and 30 rats were randomly divided into control group,tail suspension group and drug administration tail suspension group with 10 rats in each group for a total of 28 *** tail group was given *** BLa80 by intragastric administration,and the other two groups were given water intragastric administration,the concentration of intragastric administration was 0.1 g/mL,and each rat was 1 mL/***&eosin staining was used to observe the histopathological changes in each segment of the intestine of each group,and the expression levels of SCF,c-kit,extracellular signal-regulated kinase(ERK)and p-ERK in the gastric antrum of each group were detected by Western blotting and *** fecal flora and mucosal flora of rats in each group were detected by 16S *** Simulated microgravity resulted in severe exfoliation of villi of duodenum,jejunum and ileum in rats,marked damage,increased space between villi,loose arrangement,shortened columnar epithelium of colon,less folds,narrower mucosal thickness,reduced goblet cell number and crypts,and significant improvement after probiotic *** microgravity reduced the expressions of SCF and c-kit,and increased the express

关键词： Simulated microgravity Rat Intestinal flora Gastrointestinal motility Stem cell factor/c-kit signaling pathway

Kangfuxin solution alleviates esophageal stenosis after endoscopic submucosal dissection:A natural ingredient strategy

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World Journal of Gastroenterology 2025年第1期31卷 110-125页

作者： Xin Zhou Dan Ma yi-Xiang He Jing Jin Hong-Lian Wang Yun-feng Wang Fan Yang Jian-Qin Liu Jie Chen Zhi Li Department of Spleen and Stomach Diseases the Affiliated Traditional Chinese Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina The Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Digestive System Diseases of Luzhou City The Affiliated Traditional Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina Department of Gastroenterology Changhai HospitalNaval Medical UniversityShanghai 20082China Research Center of Integrated Chinese and Western Medicine The Affiliated Traditional Chinese Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina School of Integrated Traditional Chinese and Western Clinical Medicine North Sichuan Medical CollegeNanchong637100Sichuan ProvinceChina

BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after *** To examine the effectiveness and underlying mechanism of Kangfuxin solution(KFX)in mitigating excessive fibrotic repair of the esophagus *** Pigs received KFX at 0.74 mL/kg/d for 21 days after esophageal full circumferential *** examinations occurred on days 7 and 21 *** vitro,recombinant transforming growth factor(TGF)-β1(5 ng/mL)induced a fibrotic microenvironment in primary esophageal fibroblasts(pEsF).After 24 hours of KFX treatment(at 1.5%,1%,and 0.5%),expression ofα-smooth muscle actin-2(ACTA2),fibronectin(FN),and type collagen I was *** signaling was analyzed,including TGF-β1,Smad2/3,and phosphor-smad2/3(p-Smad2/3).RESULTS Compared to the Control group,the groups treated with KFX and prednisolone exhibited reduced esophageal stenosis,lower weight loss rates,and improved food tolerance 21 d after *** treatment,Masson staining revealed thinner and less dense collagen fibers in the submucosal ***,the expression of fibrotic effector molecules was notably ***,KFX downregulated the transduction levels of fibrotic functional molecules such as TGF-β1,Smad2/3,and p-Smad2/*** vitro,pEsF exposed to TGF-β1-induced fibrotic microenvironment displayed increased fibrotic activity,which was reversed by KFX treatment,leading to reduced activation of ACTA2,FN,and collagen *** 1.5%KFX treatment group showed decreased expression of p-Smad 2/3 in TGF-β1-activated *** KFX showed promise as a therapeutic option for post-full circumferential esophageal ESD strictures,potentially by suppressing fibroblast fibrotic activity through modulation of the TGF-β1/Smads signaling pathway.

关键词： Kangfuxin solution Natural component Endoscopic submucosal dissection Esophagus stricture Fibrosis

The spike layer solution to singular perturbation Robin boundary value problem for higher order elliptic equation

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Applied Mathematics(A Journal of Chinese Universities) 2020年第4期35卷 410-416页

作者： feng yi-hu hou Lei Department of Mathematics Shanghai UniversityShanghai 200444China

The singularly perturbed Robin boundary value problem for the higher order elliptic equation is *** suitable conditions,the existence and asymptotic behavior of solution to the boundary value problems are *** uniform ... 详细信息

关键词： nonlinear Robin problem spike layer

黑磷/黑砷异质结纳米器件热电性质应力调控研究

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原子与分子物理学报 2025年第1期42卷 69-74页

作者：戎杙邱乙峰张蓓新疆大学物理科学与技术学院乌鲁木齐830046

探索新型高性能低维热电纳米材料已成为国家重大发展策略.论文采用密度泛函理论结合非平衡态格林函数方法研究了由黑磷、黑砷纳米带构建异质结构在2%、4%、6%和8%四种拉伸应变作用下热电性能调控机理.研究结果表明,6%拉伸应变较其他情形... 详细信息

探索新型高性能低维热电纳米材料已成为国家重大发展策略.论文采用密度泛函理论结合非平衡态格林函数方法研究了由黑磷、黑砷纳米带构建异质结构在2%、4%、6%和8%四种拉伸应变作用下热电性能调控机理.研究结果表明,6%拉伸应变较其他情形,能够更有效抑制声子输运行为;与此同时,拉伸应变对于器件的电子输运的调控效果并不明显.在费米能附近,黑磷/黑砷异质结纳米器件在6%拉伸应变调控下热电优值达到最大值2.31.

关键词：黑磷黑砷异质结应力热电性质

Price Competition in the Random Coefficient Attraction Choice Models with Linear Cost

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Journal of the Operations Research Society of China 2022年第3期10卷 623-658页

作者： Xiao-yi feng Yang-Yang Xie hou-Min Yan Department of Model Risk Management The Hongkong and Shanghai Banking Corporation LimitedHong KongChina International Institute of Finance School of ManagementUniversity of Science and Technology of ChinaHefei230026AnhuiChina Department of Management Sciences College of BusinessCity University of Hong KongHong KongChina

We study the pricing game between competing retailers under various random coefficient attraction choice *** characterize existence conditions and structure properties of the ***,we explore how the randomness and cost parameters affect the equilibrium prices and profits under multinomial logit(MNL),multiplicative competitive interaction(MCI)and linear attraction choice ***,with bounded randomness,for the MCI and linear attraction models,the randomness always reduces the retailer’s ***,for the MNL model,the effect of randomness depends on the product’s value *** high-end products(i.e.,whose value gap is higher than a threshold),the randomness reduces the equilibrium profit,and vice *** results suggest high-end retailers in MNL markets exert more effort in disclosing their exact product performance to *** also reveal the effects of randomness on retailers’pricing *** results help retailers in making product performance disclosure and pricing decisions.

关键词： Pricing game Random coefficient choice models Equilibrium existence Effects of randomness