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The relationship between SPARC expression in primary tumor and metastatic lymph node of resected pancreatic cancer patients and patients' survival

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Hepatobiliary & Pancreatic Diseases International 2017年第1期16卷 104-109页

作者： Xin-zhe Yu Zhong-Yi Guo Yang Di feng Yang Qi Ouyang De-Liang Fu Chen jin Department of Pancreatic Surgery Huashan HospitalFudan UniversityShanghai 200040China Department of Pathology Huashan HospitalFudan UniversityShanghai 200040China Institute of Pancreatic Disease Fudan UniversityShanghai 200040China

BACKGROUND： Previous researches in pancreatic cancer demonstrated a negative correlation between secreted protein acidic and rich in cysteine （SPARC） expression in primary tumor and survival, but not for SPARC expression in lymph node. In the present study, we aimed to evaluate the SPARC expression in various types of tissues and its impact on patients＇ prognosis. METHODS： The expression of SPARC was examined by immunohistochemistry in resected pancreatic cancer specimens. Kaplan-Meier analyses and Cox proportional hazards regres- sion were applied to assess the mortality risk. RESULTS： A total of 222 tissue samples from 73 patients were collected to evaluate the SPARC expression, which included 73 paired primary tumor and adjacent normal tissues, 38 paired metastatic and normal lymph nodes. The proportion of posi tive SPARC expression in metastatic lymph node was high （32/38）, whereas in normal lymph node it was negative （0/38）. Positive SPARC expression in primary tumor cells was associ- ated with a significantly decreased overall survival （P=0.007） and disease-free survival （P=0.003）, whereas in other types of tissues it did not show a predictive role for prognosis. Univariate and multivariate analyses both confirmed this significance. CONCLUSION： SPARC can serve a dual function role as both predictor for prognosis and potentially biomarker for lymph node metastasis in resected pancreatic cancer patients.

关键词： pancreatic cancer SPARC expression immunohistochemistry prognostic marker lymph node metastasis

Tearing Toughness of Ductile Metals

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Acta Metallurgica Sinica(English Letters) 2016年第2期29卷 150-155页

作者： Cui-Hong Li Qi-Qiang Duan zhe-feng Zhang Shenyang National Laboratory for Materials Science Institute of Metal Research Chinese Academy of Sciences

A new parameter, i.e., tearing toughness, was employed to characterize the mechanical properties of some ductile metals （Cu, Cu-2 wt% Be, Cu-Al alloys, and some steels） by using three-leg trousers tearing tests. The experi- mental results demonstrate that their tearing toughness is not a physical constant and shows a close relationship with the materials＇ types and microstructures. It can be inferred that the tearing toughness of different ductile metals has their respective variation range, expectantly, and may be represented by the comprehensive mechanical properties of strength and ductility for various ductile materials.

关键词： Ductile metals Strength Ductility Tearing toughness

Poly(ionic liquid)-Based Energy and Electronic Devices

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Chinese Journal of Chemistry 2022年第9期40卷 1099-1108页

作者： Jiangna Guo zhe Sun Yingjie Zhou feng Yan Jiangsu Engineering Laboratory of Novel Functional Polymeric Materials College of ChemistryChemical Engineering and Materials ScienceSoochow UniversitySuzhouJiangsu 215123China State Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of Materials Science and EngineeringDonghua UniversityShanghai 201620China

Poly(ionic liquid)s(PILs)refer to a polymeric architecture with repeating ionic liquid species in each *** are attracting rapidly increasing interest because of their diverse structures and facial *** group focused on the design and synthesis of PILs for various applications in the past decade,including polyelectrolytes,biomedical materials,and other related *** this review,we briefly summarized our recent studies on the application of PiLs for energy and electronic devices,emphasizing the controllable synthesis and regulation of specific structures and *** unique properties and designable structures of PILs will inspire further investigation in an extensive variety of potential applications.

关键词： Poly(ionic liquid)s Energy device Sensors Polymers Materials science

Almost Periodic Solutions by the Harmonic Balance Method

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Acta Mathematicae Applicatae Sinica 2022年第4期38卷 943-954页

作者： Ji-feng CHU Zuo-huan zheNG zhe ZHOU Department of Mathematics Shanghai Normal UniversityShanghai 200234China Academy of Mathematics and Systems Science Chinese Academy of SciencesBeijing 100190China School of Mathematical Sciences University of Chinese Academy of SciencesBeijing 100049China College of Mathematics and Statistics Hainan Normal UniversityHaikou 571158China

We consider non-autonomous ordinary differential equations in two *** is the one-dimensional case that admits a condition of hyperbolicity,and the other one is the higher-dimensional case that admits an exponential *** differential equations of this kind,we give a rigorous treatment of the Harmonic Balance Method to look for almost periodic solutions.

关键词： almost periodic solution Harmonic balance method exponential dichotomy

Data mining algorithm and framework for identifying HVAC control strategies in large commercial buildings

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Building Simulation 2021年第1期14卷 63-74页

作者： zhe Chen Peng Xu Fan feng Yifan Qiao Wei Luo Department of Mechanical and Energy Engineering Tongji UniversityShanghai201804China Department of Mechanical Engineering The University of AlabamaTuscaloosaAL35487USA

Heating,Ventilation,and Air-Conditioning(HVAC)control strategies are set arbitrarily in many commercial buildings by operators,who sometimes lack relevant skills and professional *** is acknowledged that improving the control strategy of HVAC is feasible and valid,which as a consequence can improve the overall HVAC performance of existing ***,it is quite difficult for an outsiders or a commissioning agent to tell what the HVAC control strategies are and whether they are implemented appropriately in existing *** paper is intended to carry out analysis on the data about Building Automation System(BAS),as well as the data about building energy,for the purpose of identifying the control strategies of HVAC in a given building by using data mining *** the results can be adopted by us to determine whether the building is under faulty operation or is running under suboptimal *** this paper,what are proposed are algorithms of data mining identification for some specific HVAC control strategies,including DR on/off strategy,DR reset strategy and temperature reset strategy of chilled *** the basis of data mining algorithms,a framework is then developed so as to identify these strategies,and the main scenario of this identification framework is known as analyzing many commercial buildings on an energy monitoring platform of a public *** framework takes the sensor data obtained from HVAC,including temperature,flowrate,and electricity usage,as input,which is followed by the application of Image Segmentation and PCA algorithm for ***,based on these input variables,XGBoost algorithm is employed to determine whether these strategies have been implemented in buildings or *** order to get the data for training and testing the framework,EnergyPlus Runtime Language is adopted for the application of different strategies.t is finally shown by the result that the identification algorithm can achieve the a

关键词： HVAC control strategy identification data mining

Failure analysis of crevice corrosion on 304 stainless steel tube heat exchanger

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Journal of Iron and Steel Research International 2023年第8期30卷 1490-1498页

作者： Chen Dong Shen Qu Chang-ming Fu zhe-feng Zhang Failure Analysis Center for Materials Institute of Metal ResearchChinese Academy of SciencesShenyang 110016LiaoningChina

The cause of the premature failure of 304 stainless steel tube heat exchanger was *** unique skeleton structure inside the leakage point reveals that this is a new damage mechanism caused by a δ+γ two-phase structure and crevice *** three-dimensional structure of the leakage point was demonstrated using X-ray diffraction *** results of scanning electron microscope examination show the microstructure of the weld to be columnar and *** is found by electron probe microscope analysis and transmission electron microscopy that columnar dendrites consisted of γ-dendrite and an amount of δ-ferrite phases at the dendrite *** corrosion test results confirmed that the corrosion medium was the chloride *** corrosion of chloride ions occurred at weld defects on the inner wall thus forming a concentration *** of columnar dendrites were then corroded by chloride ions and δ-ferrite phases on the grain boundaries were retained,which formed the particular skeleton corrosion *** a result,it led to leakage when the corrosion of weld occurred from the inner wall to the outer wall.

关键词： Crevice corrosion Weld defect Chloride ions δ-ferrite Skeleton structure 304 stainless steel

Sulfonated Polyimides Containing 1,2,4-Triazole Groups for Proton Exchange Membranes

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Chinese Journal of Polymer Science 2014年第7期32卷 941-952页

作者： Rui Lei 高连勋 Ri-zhe jin Xue-peng Qiu Shaanxi Coal and Chemical Technology Institute Co. Ltd. State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied ChemistryChinese Academy of Sciences

A series of sulfonated polyimide copolymers as novel proton exchange materials were synthesized by the polycondensation of 1,4,5,8-naphthalene-tetracarboxylic dianhydride （NTDA）, sulfonated diamine based on pyridine group and diamine containing N-phenyl-1,2,4-triazole moiety. Flexible, transparent and tough membranes with high thermal stability and good mechanical properties were obtained. They exhibited good stability in boiling water and Fenton＇s reagent at 80 ℃. More interestingly, a nonlinear relationship between proton conductivities of the resulting membranes and the degree of sulfonation （DS） was observed. The membrane with 50% DS exhibited the maximum proton conductivity, which was due to the combinational contributions of sulfonic acid and N-pheny-1,2,4-triazole groups. Thus, the N-phenyl-l,2,4- triazole moiety in this study not only can depress water absorption but also increase proton conductivity, especially at low DS.

关键词： Triazole Acid-base interaction Sulfonated polyimide Proton exchange membrane.

Straightforward Guess and Determine Analysis Based on Genetic Algorithm

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Journal of Systems Science & Complexity 2022年第5期35卷 1988-2003页

作者： CAO Chunping CEN zhe feng Xiutao WANG Zhangyi ZHU Yamin Department of Computer Science and Technology University of Shanghai for Science and TechnologyShang-hai 200093China Key Laboratory of Mathematics Mechanization Academy of Mathematics and Systems ScienceChinese Academy of SciencesBeijing 100190China School of Cyber Science and Engineering Wuhan UniversityWuhan 430072China School of Science Xi'an Technological UniversityXi'an 710021China

With the development of artificial intelligence,the genetic algorithm has been widely used in many *** cryptography,the authors find it is natural to code an individual and design its fitness in a genetic algorithm for a straightforward guess and determine analysis(SGDA,in short).Based on this observation,the authors propose an SGDA based on genetic *** it with the other three SGDAs based on exhaustive search,MILP method and CPP method respectively,the authors illustrate its effectiveness by three stream ciphers:Small scale SNOW 2.0,medium scale Enocoro-128v2 and large scale *** results show our method is significantly superior to them,especially for Trivium,the method can find a solution of 165 variables in less than one hour,while the other three methods are not applicable due to its enormous search space of size 2^(619.37).As far as we know,it is a best solution in an SGDA for Trivium so far.

关键词： Enocoro-128v2 genetic algorithm guess and determine analysis SNOW 2.0 trivium

The effect of single-horn glaze ice on the vortex structures in the wake of a horizontal axis wind turbine

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Acta Mechanica Sinica 2015年第1期31卷 62-72页

作者： zhe-Yan jin Qiao-Tian Dong Zhi-Gang Yang School of Aerospace Engineering and Applied Mechanics Tongji University School of Automotive Studies Tongji University Shanghai Automotive Wind Tunnel Center

The present study experimentally investigated the effect of a simulated single-horn glaze ice accreted on ro- tor blades on the vortex structures in the wake of a hori- zontal axis wind turbine by using the stereoscopic particle image velocimetry （Stereo-PIV） technique. During the ex- periments, four horizontal axis wind turbine models were tested, and both ＂free-run＂ and ＂phase-locked＂ Stereo-PIV measurements were carried out. Based on the ＂free-run＂ measurements, it was found that because of the simulated single-horn glaze ice, the shape, vorticity, and trajectory of tip vortices were changed significantly, and less kinetic en- ergy of the airflow could be harvested by the wind turbine. In addition, the ＂phase-locked＂ results indicated that the pres- ence of simulated single-horn glaze ice resulted in a dramatic reduction of the vorticity peak of the tip vortices. Moreover, as the length of the glaze ice increased, both root and tip vortex gaps were found to increase accordingly.

关键词： Stereo-PIV Single-horn glaze ice. Tip vorticesRoot vortices Wind turbine icing