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马善祥:“老马”带“小马” 带出调解大队伍

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社会与公益 2024年第2期 63-65页

作者：姜峰不详

“老马”是哪个哟?2023年11月下旬,一封来自中央党校(国家行政学院)的邀请函发到了重庆市江北区观音桥街道办事处,请退休多年的马善祥到校为全体学员和教职工作报告——扎根基层30余年,先后获评“时代楷模”“全国优秀共产党员”“基层... 详细信息

“老马”是哪个哟?2023年11月下旬,一封来自中央党校(国家行政学院)的邀请函发到了重庆市江北区观音桥街道办事处,请退休多年的马善祥到校为全体学员和教职工作报告——扎根基层30余年,先后获评“时代楷模”“全国优秀共产党员”“基层社会治理创新的优秀人民调解员”等荣誉称号,顶大的“面子”,老马配得上。

关键词：国家行政学院人民调解员街道办事处荣誉称号中央党校基层社会治理创新重庆市江北区观音桥

能量场辅助激光诱导等离子体加工透明硬脆材料的研究现状及发展趋势

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机械工程学报 2024年第9期60卷 254-272页

作者：江安娜言兰王宁昌姜峰李卓温秋玲卢希钊黄辉华侨大学机电及自动化学院厦门361021 脆性材料产品智能制造技术国家地方联合工程研究中心厦门361021 高性能工具全国重点实验室(郑州磨料磨具磨削研究所有限公司) 郑州450000 华侨大学制造工程研究院厦门361021 高性能工具全国重点实验室(华侨大学) 厦门361021

能量场辅助激光诱导等离子体加工技术是一种新兴的制造技术。基于传统的激光加工技术,通过引入热场、电场、磁场、化学场等能场进行创新,提高激光加工过程的可控性,不仅实现了透明硬脆材料纳米级甚至亚纳米级高精度制造,也有利于满足超... 详细信息

能量场辅助激光诱导等离子体加工技术是一种新兴的制造技术。基于传统的激光加工技术,通过引入热场、电场、磁场、化学场等能场进行创新,提高激光加工过程的可控性,不仅实现了透明硬脆材料纳米级甚至亚纳米级高精度制造,也有利于满足超精密制造的高质量、低损伤要求。从热场、磁场、电场、化学场分别具体阐述了不同的能量场辅助对激光加工技术的影响,通过分析激光机理和能量场辅助机理总结热场、电场、磁场和化学场对激光加工中的热能、光能、动能和表面能的影响原理,并介绍了能量场辅助激光加工的设备及工艺方法,最后总结能量场辅助激光加工技术目前存在的不足及未来面临的挑战,为进一步发展多能场复合辅助激光诱导等离子体加工技术奠定基础。

关键词：透明硬脆材料电场辅助激光加工磁场辅助激光加工热场辅助激光加工化学场辅助激光加工

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玉屏风散联合西药治疗慢性荨麻疹临床观察

中国中医药现代远程教育 2024年第8期22卷 146-148页

作者：江锋江西省安福县人民医院皮肤科江西安福343200

目的探究玉屏风散在慢性荨麻疹中的治疗效果。方法选取2019年3月—2021年3月于安福县人民医院治疗的70例慢性荨麻疹患者,随机分为两组,各35例。对照组采用西药治疗,研究组采用西药联合玉屏风散治疗。对比两组临床疗效、中医证候积分... 详细信息

目的探究玉屏风散在慢性荨麻疹中的治疗效果。方法选取2019年3月—2021年3月于安福县人民医院治疗的70例慢性荨麻疹患者,随机分为两组,各35例。对照组采用西药治疗,研究组采用西药联合玉屏风散治疗。对比两组临床疗效、中医证候积分、皮肤病生活质量指数(DLQI)、炎性因子水平及不良反应。结果治疗后,研究组的中医证候积分、DLQI评分、白细胞介素-4(IL-4)及白细胞介素-10(IL-10)水平均低于对照组,干扰素-γ(IFN-γ)水平高于对照组(P0.05)。结论慢性荨麻疹患者加用玉屏风散治疗,能够有效缓解临床症状、抑制炎性因子水平、提升生活质量,且不良反应较少。

关键词：瘾疹慢性荨麻疹玉屏风散中西医结合疗法

Beneficial Effects of Celastrol on Immune Balance by Modulating Gut Microbiota in Experimental Ulcerative Colitis Mice

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Genomics, Proteomics & Bioinformatics 2022年第2期20卷 288-303页

作者： Mingyue Li Weina Guo Yalan Dong Wenzhu Wang Chunxia Tian Zili Zhang Ting Yu Haifeng Zhou Yang Gui Kaming Xue Junyi Li feng jiang Alexey Sarapultsev Huafang Wang Ge Zhang Shanshan Luo Heng Fan Desheng Hu Department of Integrated Traditional Chinese and Western Medicine Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Gastroenterology Zhongda HospitalSoutheast UniversityNanjing 210009China Institute of International Education Tianjin University of Traditional Chinese MedicineTianjin 301617China Institute of Immunology and Physiology Ural Branch of the Russian Academy of SciencesEkaterinburg 620049Russia Institute of Hematology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Institute of Integrated Bioinfomedicine and Translational Science School of Chinese MedicineHong Kong Baptist UniversityHong Kong Special Administrative Region 999077China

Ulcerative colitis(UC)is a chronic inflammatory bowel disease caused by many factors including colonic inflammation and microbiota dysbiosis.Previous studies have indicated that celastrol(CSR)has strong anti-inflammatory and immune-inhibitory effects.Here,we investigated the effects of CSR on colonic inflammation and mucosal immunity in an experimental colitis model,and addressed the mechanism by which CSR exerts the protective effects.We characterized the therapeutic effects and the potential mechanism of CSR on treating UC using histological staining,intestinal permeability assay,cytokine assay,flow cytometry,fecal microbiota transplantation(FMT),16S rRNA sequencing,untargeted metabolomics,and cell differentiation.CSR administration significantly ameliorated the dextran sodium sulfate(DSS)-induced colitis in mice,which was evidenced by the recovered body weight and colon length as well as the decreased disease activity index(DAI)score and intestinal permeability.Meanwhile,CSR down-regulated the production of pro-inflammatory cytokines and up-regulated the amount of anti-inflammatory mediators at both mRNA and protein levels,and improved the balances of Treg/Th1 and Treg/Th17 to maintain the colonic immune homeostasis.Notably,all the therapeutic effects were exerted in a gut microbiota-dependent manner.Furthermore,CSR treatment increased the gut microbiota diversity and changed the compositions of the gut microbiota and metabolites,which is probably associated with the gut microbiota-mediated protective effects.In conclusion,this study provides the strong evidence that CSR may be a promising therapeutic drug for UC.

关键词： Ulcerative colitis Celastrol Gut microbiota Treg/Th balance Metabolomics

英国中小学教师《教学领导力框架》的内容、特点及启示

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教学与管理 2024年第10期 72-76页

作者：孔露冯江英新疆师范大学教育科学学院乌鲁木齐830017 川北幼儿师范高等专科学校学前教育学院四川广元628017

领导教学型教师是教师队伍建设中不可忽视的重要群体。为了给所有专注于课堂教学的教师专业发展提供良好的服务和支持,英国政府于2020年10月出台了中小学教师《教学领导力框架》。该框架呈现出显著特征:重视数据运用,彰显教学改革的循... 详细信息

领导教学型教师是教师队伍建设中不可忽视的重要群体。为了给所有专注于课堂教学的教师专业发展提供良好的服务和支持,英国政府于2020年10月出台了中小学教师《教学领导力框架》。该框架呈现出显著特征:重视数据运用,彰显教学改革的循证意识;关注处境不利儿童,突出适应性教学;着力教师专业发展,强调文化环境创设;发挥团队协作效应,聚焦领导教学型教师的引领作用。作为英国国家认证的职业资格,该框架也为我国领导教学型教师队伍建设提供了有益的借鉴和启示。

关键词：英国中小学教师教学领导力框架领导教学型教师

Significant enhancement of crystallization kinetics of polylactide in its immiscible blends through an interfacial effect from comb-like grafted side chains

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Science China Chemistry 2016年第5期59卷 609-618页

作者： Yin Chen Yaqiong Zhang feng jiang JunyangWang Zhaohua Xu Zhigang Wang CAS Key Laboratory of Soft Matter Chemistry Hefei National Laboratory for Physical Sciences at the MicroscaleDepartment of Polymer Science and EngineeringUniversity of Science and Technology of ChinaHefei 230026China Department of Material Technology Jiangmen PolytechnicJiangmen 529090China

A significant enhancement in isothermal crystallization kinetics of biodegradable polylactide(PLA) in its immiscible blends can be accomplished through blending it with a comb-like copolymer. PLA was blended with poly(ethylene glycol) methyl ether acrylate(PEGA) and poly[poly(ethylene glycol) methyl ether acrylate](PPEGA, a comb-like copolymer), respectively. The results measured from phase contrast optical microscopy(PCOM) and differential scanning calorimetry(DSC) indicate that PLA and PEGA components are miscible, whereas PLA and PPEGA components are immiscible. The study of crystallization kinetics for PLA/PEGA and PLA/PPEGA blends by means of polarized optical microscopy(POM) and DSC indicates that both PEGA and PPEGA significantly increase the PLA spherulitic growth rates, G, although PLA/PPEGA blends are immiscible and the glass transition temperatures of PLA only have slight decreases. PPEGA component enhances nucleation for PLA crystallization as compared with PEGA component owing to the heterogeneous nucleation effect of PPEGA at the low composition of 20 wt%, while PLA crystallization-induced phase separation for PLA/PEGA blend might cause further nucleation at the high composition of 50 wt%. DSC measurement further demonstrates that isothermal crystallization kinetics can be relatively more enhanced for PLA/PPEGA blends than for PLA/PEGA blends. The "abnormal" enhancement in G for PLA in its immiscible blends can be explained by local interfacial interactions through the densely grafted PEGA side chains in the comb-like PPEGA, even though the whole blend system(PLA/PPEGA blends) represents an immiscible one.

关键词：等温结晶动力学聚乳酸共混物不混溶界面作用侧链接枝 DSC测量

MicroRNA-dependent development revealed by RNA interference-mediated gene silencing of LmDicerl in the migratory locust

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Insect Science 2013年第1期20卷 53-60页

作者： Yan-Li Wang Mei-Ling Yang feng jiang Jian-Zhen Zhang Le Kang Research Institute of Applied Biology Shanxi University Taiyuan State Key Laboratory of Integrated Management of Pest Insects and Rodents Institute of Zoology Chinese Academy of Sciences Beijing China

MicroRNAs （miRNAs） are small noncoding RNAs, which participate in many biological processes. The small RNA transcriptome in the migratory locust has been characterized and 50 conserved miRNA families and 185 potential locust-specific miRNA family candidates have been identified using high-throughput sequencing. However, it is unclear whether miRNAs influence a wide variety of locusts＇ biological processes, such as growth or development. In insects, Dicerl ribonuclease transforms miRNA precursors into mature miRNAs. Thus, using systemic RNA interference （RNAi） to silence the expression of Dicer1 in the migratory locust, Locusta migratoria, we reduced miRNA contents in the locust and disrupted two types of molt （nymph-nymph, and nymph-adult）. The RNAi of LmDicerl also resulted in a high mortality in L. migratora. Our study revealed that LmDicerl was essential for miRNA regulation and development ofL. migratoria. These results further support our notion that LmDicerl could serve as an excellent target for developing novel strategies for controlling this important insect pest.

关键词： development dicerl Locusta migratoria microRNA

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指数剪切流作用下海洋立管振动特性研究

海洋工程 2024年第3期42卷 32-43页

作者：周欣丹陈正寿姜峰浙江海洋大学石油化工与环境学院浙江舟山316022 太平洋海洋工程(舟山)有限公司浙江舟山316057

细长海洋立管在复杂来流作用下的涡激振动(VIV)是海洋工程领域备受关注的热点问题。采用双向流—固耦合方法,对立管在指数剪切来流作用下的涡激振动实施了数值仿真研究。基于均方根振幅包络图的显性模态分析发现,与线性剪切流工况相比,... 详细信息

细长海洋立管在复杂来流作用下的涡激振动(VIV)是海洋工程领域备受关注的热点问题。采用双向流—固耦合方法,对立管在指数剪切来流作用下的涡激振动实施了数值仿真研究。基于均方根振幅包络图的显性模态分析发现,与线性剪切流工况相比,当流速较小时,立管模型在指数剪切流作用下振幅最大值相对较小;流速较大时,指数剪切流的非线性分布致使立管的振动响应增强。通过对立管模型均方根振幅包络峰、谷处的振动响应频率分析发现,在波峰位置处振动频率单一且较为稳定,而在相邻波谷位置处多频共存现象显著,两者有显著差异。沿管的轴向波形主要表现为驻波主导和驻波—行波混合模式,行波一般间歇发生,流速越大发生频次愈高,其在横流向的传播方向通常由高流速区段传递至低流速区段。指数剪切流作用下,沿管体轴向各截面位置处的旋涡脱落模式差异显著,高流速段尾流区的旋涡发放具有较强的周期性,涡管完整且与管轴存在一定偏离角度,低流速段蜂窝状离散涡旋较多。

关键词：海洋立管指数剪切流涡激振动流—固耦合多模态响应

Partially stabilized tetragonal ZrO_(2) whiskers with preferred [001] direction derived from CaF_(2)

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Journal of Materiomics 2021年第4期7卷 879-885页

作者： Xuefeng Liu Quan Zhang Jianmin Liu Tao Wang Yanqiao Xu Jian Liang feng jiang Guo feng Weihui jiang School of Materials Science and Engineering Jingdezhen Ceramic InstituteJingdezhen333403China National Engineering Research Center for Domestic&Building Ceramics Jingdezhen333001China

The simultaneous control of crystal phase stability and one-dimensional growth has always been the major challenge for the preparation of tetragonal zirconia whiskers.In this study,we report a facile molten salt processing that utilizes CaF_(2) as a stabilizer and adsorbent to meet the phase and morphology requirements.The processes of stabilization,phase transition,ion adsorption and formation of special morphology involved in zirconia growth were investigated by XRD,IR,SEM,DTA-TG and TEM.By controlling the amount of CaF_(2)(15 wt%)added in the reaction precursor,tetragonal zirconia whiskers with a desired aspect ratio(>16)can be synthesized,which show single crystalline nature and[001]preferred direction.Ca ions doped at low temperature inhibit the occurrence of phase transition,which allows the tetragonal structure to be retained to room temperature.The inducement and pattern of whisker growth are supposed to be F-adsorption and screw dislocation elongation,respectively.The specific selectivity of surface adsorbed ions to certain zirconia crystal planes reduces or even inhibits the epitaxial growth rate in this direction,offering a viable avenue for the morphology modulation of inorganic nanomaterials.

关键词： Tetragonal zirconia whisker Molten salt processing CaF_(2) Phase stability Ion adsorption