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Depression mechanism of sulfite ions on sphalerite and Pb^(2+)activated sphalerite in the flotation separation of galena from sphalerite

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 335-345页

作者： feng zhang Chenyang zhang Linlin Wu Wei Sun Hongliang zhang Jianhua Chen Yong Pei Songjiang Li Engineering Research Center of Ministry of Education for Carbon Emission Reduction in Metal Resource Exploitation and Utilization Hunan International Joint Research Center for Efficient and Clean Utilization of Critical Metal Mineral ResourcesSchool of Minerals Processing and BioengineeringCentral South UniversityChangsha 410083China State Key Laboratory of Mineral Processing Beijing General Research Institute of Mining&MetallurgyBeijing 100160China Hunan Provincial Key Laboratory of Micro&Nano Materials Interfaces Science College of Chemistry and Chemical EngineeringCentral South UniversityChangsha 410083China School of Resources Environment and MaterialsGuangxi UniversityNanning 530004China Department of Chemistry Xiangtan UniversityXiangtan 411105China China Railway Resource Group Co.Ltd Beijing 102300China

The depression mechanism of sulfite ions on sphalerite and Pb^(2+)activated sphalerite in the flotation separation of galena from sphalerite still lacked in-depth ***,the depression mechanism of sulfite ions on sphalerite and Pb^(2+)activated sphalerite in the flotation separation of galena from sphalerite was further systematically investigated with experiments and density functional theory(DFT)*** X-ray photoelectric spectroscopy(XPS)results,DFT calculation results,and frontier molecular orbital analysis indicated that sulfite ions were difficult to be adsorbed on sphalerite surface,suggesting that sulfite ions achieved depression effects on sphalerite through other non-adsorption ***,the oxygen content in the surface of sphalerite treated with sulfite ions in creased,which enhanced the hydrophilicity of the sphalerite and further increased the difference in hydrophilicity between sphalerite and ***,sulfite ions were chelated with lead ions to form PbSO_(3)in *** hydrophilic PbSO_(3)was more easily adsorbed on sphalerite than *** interaction between sulfite ions and lead ions could effectively inhibit the activation of *** addition the UV spectrum showed that after adding sulfite ions,the peak of perxanthate in the sphalerite treated xanthate solution was significantly stronger than that in the galena with xanthate solution,indicating that xanthate interacted more readily with sulfite ions and oxygen mo lecules within the sphalerite system,leading to the formation of ***,sulfite ions hardly depressed the flotation of ga lena and could promote the flotation of galena to some *** study deepened the understanding of the depression mechanism o sulfite ions on sphalerite and Pb^(2+)activated sphalerite.

关键词： sphalerite galena sulfite ion density functional theory depression mechanism

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Copper homeostasis and neurodegenerative diseases

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Neural Regeneration Research 2025年第11期20卷 3124-3143页

作者： Yuanyuan Wang Daidi Li Kaifei Xu Guoqing Wang feng zhang International Research Laboratory of Ethnomedicine of Ministry of Education Key Laboratory of Basic Pharmacology of Ministry of EducationLaboratory Animal Center and Key Laboratory of Basic Pharmacology of Guizhou ProvinceZunyi Medical UniversityZunyiGuizhou ProvinceChina

Copper,one of the most prolific transition metals in the body,is required for normal brain physiological activity and allows various functions to work normally through its range of *** homeostasis is meticulously maintained through a complex network of copper-dependent proteins,including copper transporters(CTR1 and CTR2),the two copper ion transporters the Cu-transporting ATPase 1(ATP7A)and Cu-transporting beta(ATP7B),and the three copper chaperones ATOX1,CCS,and *** in copper homeostasis can lead to either the deficiency or accumulation of copper in brain *** evidence suggests that abnormal copper metabolism or copper binding to various proteins,including ceruloplasmin and metallothionein,is involved in the pathogenesis of neurodegenerative ***,the exact mechanisms underlying these processes are not *** is a potent oxidant that increases reactive oxygen species production and promotes oxidative *** reactive oxygen species levels may further compromise mitochondrial integrity and cause mitochondrial *** oxygen species serve as key signaling molecules in copper-induced neuroinflammation,with elevated levels activating several critical inflammatory ***,copper can bind aberrantly to several neuronal proteins,including alphasynuclein,tau,superoxide dismutase 1,and huntingtin,thereby inducing neurotoxicity and ultimately cell *** study focuses on the latest literature evaluating the role of copper in neurodegenerative diseases,with a particular focus on copper-containing metalloenzymes and copper-binding proteins in the regulation of copper homeostasis and their involvement in neurodegenerative disease *** synthesizing the current findings on the functions of copper in oxidative stress,neuroinflammation,mitochondrial dysfunction,and protein misfolding,we aim to elucidate the mechanisms by which copper contributes to a wide range of heredit

关键词： Alzheimer's disease amyotrophic lateral sclerosis disease copper homeostasis copper toxicity Huntington's disease Menkes'disease multiple sclerosis neurodegenerative disease Parkinson's disease Wilson's disease

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Unraveling the mechanism of action of Shangxia Liangji formula for treating insomnia:a metabolomics and network pharmacology approach

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Traditional Medicine Research 2025年第2期10卷 16-29页

作者： Xia-Jie Quan Hao Liang Yong-Hong Tang Li Jiang Xiong-Ying Ji feng-Ying zhang Ping zhang Bo Ouyang Department of Information The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China Department of Neurology The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China Department of Gastroscopy The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China Department of Traditional Chinese Medicine The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China

Background:Insomnia is a prevalent clinical condition and Shangxia Liangji formula(SXLJF)is a well-established method of ***,the specific mechanism of action of SXLJF remains ***:The mouse model of insomnia was established by intraperitoneal injection of ***-two mice were randomly divided into a negative control group,model group,SXLJF group(18.72 g/kg/day),and positive control group(diazepam,2 mg/kg)and treated with the corresponding drugs for 7 consecutive *** open field test and pentobarbital-induced sleeping test were ***-MS-based untargeted metabolomics and network pharmacology were applied to explore the potential targets of SXLJF for treating ***,key targets were validated using ***:Behavioral tests demonstrated that SXLJF reduced the total distance,average velocity,central distance,and sleep latency,and prolonged sleep *** and network pharmacology revealed potential targets,signaling pathways,metabolic pathways,and metabolites associated with the anti-insomnia effects of ***,tyrosine hydroxylase(TH)and tyrosine metabolism emerged as crucial metabolic pathways and targets,***-qPCR results supported the role of TH in the mechanism of SXLJF in treating ***:In conclusion,TH and tyrosine metabolism may represent significant targets and pathways for SXLJF in treating insomnia.

关键词： Shangxia Liangji formula insomnia metabolomics network pharmacology tyrosine hydroxylase tyrosine metabolism

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构建聚己内酯/纳米金刚石-磷脂复合材料及性能评价

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中国组织工程研究 2025年第16期29卷 3380-3387页

作者：田家宇李多华张锋冯虎孙伟徐州医科大学江苏省徐州市221000 徐州医科大学附属医院骨科江苏省徐州市221000

背景:聚己内酯因具有良好的加工和降解性能在骨组织工程中得到广泛应用,但其较差的亲水性及机械强度并不能为成骨细胞提供良好的生长环境。目的:制备聚己内酯/纳米金刚石-磷脂复合材料,评估其生物相容性和体外促成骨分化能力。方法:使... 详细信息

背景:聚己内酯因具有良好的加工和降解性能在骨组织工程中得到广泛应用,但其较差的亲水性及机械强度并不能为成骨细胞提供良好的生长环境。目的:制备聚己内酯/纳米金刚石-磷脂复合材料,评估其生物相容性和体外促成骨分化能力。方法:使用磷脂对纳米金刚石进行改性,以聚己内酯为原材料,采用溶液浇铸法制备含不同质量比例(0%,2.5%,7.5%,10%)纳米金刚石-磷脂的聚己内酯/纳米金刚石-磷脂复合膜,使用聚己内酯/纳米金刚石膜进行对比,通过对各组材料表面形貌、元素组成、力学性能及水接触角的观察,选取理化性能较佳的复合膜。将MC3T3-E1细胞分别接种于纯聚己内酯膜、聚己内酯/7.5%纳米金刚石-磷脂膜及聚己内酯/7.5%纳米金刚石膜,检测细胞增殖、黏附及成骨分化能力。结果与结论:①通过扫描电镜及表面元素组成证实聚己内酯/纳米金刚石-磷脂复合膜制备成功,与纯聚己内酯膜相比,聚己内酯/7.5%纳米金刚石-磷脂膜的拉伸强度提高了86.06%,弹性模量提高了54.76%,水接触角降低至70.0°,显示出良好的理化性能;②CCK-8检测结果显示,相较于纯聚己内酯膜、聚己内酯/7.5%纳米金刚石膜,聚己内酯/7.5%纳米金刚石-磷脂膜可促进MC3T3-E1细胞的增殖;鬼笔环肽染色显示,相较于聚己内酯/7.5%纳米金刚石膜,纯聚己内酯膜、聚己内酯/7.5%纳米金刚石-磷脂膜上的MC3T3-E1细胞多为菱形或纺锤形纤维状,细胞连接更紧密;碱性磷酸酶染色显示,相较于纯聚己内酯膜、聚己内酯/7.5%纳米金刚石膜,聚己内酯/7.5%纳米金刚石-磷脂膜上的MC3T3-E1细胞展现了更强的成骨分化能力;③结果表明,聚己内酯/纳米金刚石-磷脂复合材料具有良好的力学性能、亲水性、生物相容性及体外促成骨分化能力。

关键词：纳米金刚石聚己内酯磷脂溶液浇铸法 MC3T3-E1细胞成骨分化骨组织工程

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自主D1规格与API CK-4规格对比分析及自主复合剂技术开发

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石油炼制与化工 2025年第1期56卷 160-166页

作者：孙文斌张倩黄作鑫张峰中石化石油化工科学研究院有限公司北京100083

综合对比了柴油机油我国自主D1规格和API CK-4规格在理化性能指标、发动机台架试验性能指标等方面的差异;进而,结合中国石化自主开发的符合API CK-4规格的柴油机油复合剂技术(RIPP C0010)在两种规格发动机台架试验中的评价结果,系统分... 详细信息

综合对比了柴油机油我国自主D1规格和API CK-4规格在理化性能指标、发动机台架试验性能指标等方面的差异;进而,结合中国石化自主开发的符合API CK-4规格的柴油机油复合剂技术(RIPP C0010)在两种规格发动机台架试验中的评价结果,系统分析D1规格与API CK-4规格的相关性,以及RIPP C0010柴油机油技术对国产发动机的适用性。结果表明:除柴油喷嘴剪切后高温高剪切黏度存在差异外,D1规格与API CK-4规格的其他理化性能指标,包括高低温运动黏度、蒸发损失率、高温抗腐蚀性、抗泡性能、元素含量等均基本相同;D1规格的4种台架试验均可以评价多项油品性能,如抗氧化性能、清净性能、分散性能、抗磨性能等,实现了API CK-4规格10种台架试验的评价效果,但仍需进一步完善其基础油互换规则和黏度级别延伸规则;行车试验结果表明,自主研发RIPP C0010柴油机油可满足重载柴油发动机60000 km换油周期使用要求。

关键词：柴油机油 D1规格 API CK-4规格发动机台架试验

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STOCHASTIC MAXIMUM PRINCIPLE FOR MIXED REGULAR-SINGULAR CONTROL PROBLEMS OF FORWARD-BACKWARD SYSTEMS

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Journal of Systems Science & Complexity 2013年第6期26卷 886-901页

作者： zhang feng School of Mathematics and Quantitative Economics Shandong University of Finance and Economics

This paper considers a stochastic optimal control problem of a forward-backward system with regular-singular controls where the set of regular controls is not necessarily convex and the regular control enters the diffusion *** control problem is difficult to solve with the classical method of spike *** authors use the approach of relaxed controls to establish maximum principle for this stochastic optimal control *** optimality conditions are also investigated.

关键词： Forward-backward system maximum principle relaxed control singular control.

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Challenges and opportunities facing game theory and control: an interview with Tamer Ba?ar

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National Science Review 2020年第7期7卷 1142-1146页

作者： Ji-feng zhang the Academy of Mathematics and Systems Science of the Chinese Academy of Sciences

The Control community has recently witnessed an almost exponentially growing interest in the application of game-theoretic concepts and tools in research on control, multi-agent systems, and networks. In an interview with NSR, Professor Tamer Ba?ar, a member of the US National Academy of Engineering, Swanlund Endowed Chair and CAS Professor of Electrical and Computer Engineering, and Director of the Center for Advanced Study at the University of Illinois at Urbana-Champaign in the USA, former president of both the IEEE Control

关键词： Game theory

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Stochastic maximum principle for optimal control problems involving delayed systems

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Science China(Information Sciences) 2021年第1期64卷 269-271页

作者： feng zhang School of Mathematics and Quantitative Economics Shandong University of Finance and Economics

Dear editor,The main objective of this study is to investigate one type of stochastic optimal control problem for a delayed system using the maximum principle *** existing research can be categorized into two *** the first category,the adjoint equation comprises two backward stochastic differential equations (BSDEs) and one backward ordinary differential equation (BODE),which is assumed to have a zero solution;see e.g.,[1-3].However,there is still scope for improvement in this research ***,a special setting is considered for the system parameters;see e.g.,(3.9)and (3.12) in *** BODE is assumed to result in a zero solution when the necessary maximum principle is strictly applied;see e.g.,Theorem 5.1 in *** the second category,a typee of anticipated/time-advanced BSDE is introduced as the adjoint equation;see e.g.,[1,4-7].

关键词： Information Systems and Communication Service

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Coupled Dynamics and Integrated Control for Position and Attitude Motions of Spacecraft:A Survey

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IEEE/CAA Journal of Automatica Sinica 2023年第12期10卷 2187-2208页

作者： feng zhang Guangren Duan the Research and Development Center China Academy of Launch Vehicle TechnologyBeijing 100076China IEEE the Center for Control Science and Technology Southern University of Science and TechnologyShenzhen 518055 the Center for Control Theory and Guidance Technology Harbin Institute of TechnologyHarbin 150001China

Inspired by the integrated guidance and control design for endo-atmospheric aircraft,the integrated position and attitude control of spacecraft has attracted increasing attention and gradually induced a wide variety of study results in last over two decades,fully incorporating control requirements and actuator characteristics of space *** paper presents a novel and comprehensive survey to the coupled position and attitude motions of spacecraft from the perspective of dynamics and *** this end,a systematic analysis is firstly conducted in details to show the position and attitude mutual couplings of ***,in terms of the time discrepancy between spacecraft position and attitude motions,space missions can be categorized into two types:space proximity operation and space orbital *** on this classification,the studies on the coupled dynamic modeling and the integrated control design for position and attitude motions of spacecraft are sequentially summarized and *** the one hand,various coupled position and dynamic formulations of spacecraft based on various mathematical tools are reviewed and compared from five aspects,including mission applicability,modeling simplicity,physical clearance,information matching and *** the other hand,the development of the integrated position and attitude control of spacecraft is analyzed for two space missions,and especially,five distinctive development trends are captured for space operation ***,insightful prospects on future development of the integrated position and attitude control technology of spacecraft are proposed,pointing out current primary technical issues and possible feasible solutions.

关键词： Coupled position and attitude dynamic modeling integrated position and attitude control position and attitude coupling analysis spacecraft space missions

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Existence of Optical Vortex Solitons in Pair Plasmas

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Acta Mathematicae Applicatae Sinica 2023年第3期39卷 571-582页

作者： Rui-feng zhang School of Mathematics and Statistics Henan UniversityKaifeng 475004China

Optical vortices arise as phase dislocations of light fields and they are of importance in modern optical *** this study,we employ the calculus of variations method to develop an existence theory for the steady state vortex solutions of a nonlinear Schr?dinger type equation to model light waves that propagate in a medium with a new focusing-defocusing ***,we demonstrate the existence of positive radially symmetric solutions by constrained minimization,where we give some interesting explicit estimates related to vortex winding numbers and the wave propagation ***,we establish the existence of saddle-point solutions through a mountain-pass argument.

关键词： Calculus of variations mountain-pass theorem pair plasmas nonlinear Schr?dinger type equation optical vortices

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