检索结果-南通市图书馆

Vanadium nitride quantum dots@carbon skeleton anode material synthesized via in situ oxidation initiation strategy

Tungsten 2024年第3期6卷 561-573页

作者： Yi-Han fu Yuan-You Peng Lei Zhao Tian-Qi He Mei-Mei Yuan Hao Dang Rui Liu fen Ran State Key Laboratory of Advanced Processing and Recycling of Non-Ferrous Metals School of Materials Science and Engineering Lanzhou University of Technology

Vanadium nitride（VN） has received significant attention as a potential negative electrode material due to its remarkable theoretical and physical ***,the electrochemical performance needs to be improved due to its low specific surface area and the issue of being easily dissolved in *** have shown that the composite structure of carbon-coated nano sc ale VN particles could significantly increase the specific surface area of VN,and more importantly,and the carbon matrix can effectively restrain the dissolution of VN particles in the electrolyte,thereby improving its chemical and electrochemical performance,including specific capacity and cycling ***,VN quantum dots are synthesized and protected by uniformly coating the carbon skeleton on its surface via an in situ strategy of oxidation initiation,which initiates dopamine polymerization,forming a crystalline complex of polydopamine and *** heat treatment,the product is a composite material with VN quantum dots embedded in the amorphous carbon *** resulting smallsized and crosslinked carbon particles formed a graded pore structure,more reasonable channels provided for electrolyte ions transport *** the composite material was used as the negative electrode material for supercapacitors,it exhibits the specific capacity of 391.9 F·g-1at a current density of 0.5 A·g-1and excellent capacity retention rate of 83.6% after *** synthesis method of this quantum dot could be applied to other metal compounds and has potential applications in catalysis,environmental protection,and other fields.

关键词： In situ initiation Vanadium nitride Quantum dots Anode Supercapacitors

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Development and validation of a novel non-invasive test for diagnosing nonalcoholic fatty liver disease in Chinese children

引用

World Journal of Pediatrics 2024年第4期20卷 413-421页

作者： Zhe-Wen Qin Qian-Nan Ren Hong-Xi Zhang Ya-Ru Liu Ke Huang Wei Wu Guan-Ping Dong Yan Ni Jun-fen.fu Division of Endocrinology National Clinical Research Center for Child HealthNational Children’s Regional Medical CenterThe Children’s HospitalDepartment of EndocrinologyNational Clinical Research Center for Child HealthNational Children’s Regional Medical CenterThe Children’s HospitalZhejiang University School of MedicineHangzhou310052China

With the exploding prevalence of obesity,many children are at risk of developing nonalcoholic fatty liver *** anthropometric and laboratory parameters,our study aimed to develop a model to quantitatively evaluate liver fat content(LFC)in children with *** A well-characterized cohort of 181 children between 5 and 16 years of age were recruited to the study in the Endocrinology Department as the derivation *** external validation cohort comprised 77 *** assessment of liver fat content was performed using proton magnetic resonance *** and laboratory metrics were measured in all subjects.B-ultrasound examination was carried out in the external validation *** Kruskal-Wallis test,Spearman bivariate correlation analyses,univariable linear regressions and multivariable linear regression were used to build the optimal predictive *** The model was based on indicators including alanine aminotransferase,homeostasis model assessment of insulin resistance,triglycerides,waist circumference and Tanner *** adjusted R^(2)of the model was 0.589,which presented high sensitivity and specificity both in internal[sensitivity of 0.824,specificity of 0.900,area under curve(AUC)of 0.900 with a 95%confidence interval:0.783–1.000]and external validation(sensitivity of 0.918 and specificity of 0.821,AUC of 0.901 with a 95%confidence interval:0.818–0.984).Conclusions Our model based on five clinical indicators was simple,non-invasive,and inexpensive;it had high sensitivity and specificity in predicting LFC in ***,it may be useful for identifying children with obesity who are at risk for developing nonalcoholic fatty liver disease.

关键词： Biochemical markers Children Magnetic resonance spectroscopy Nonalcoholic fatty liver disease Pediatric obesity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Therapeutic Effectiveness of Leukocyte-and Platelet-rich Fibrin for Diabetic Foot Ulcers:A Retrospective Study

引用

Current Medical Science 2024年第3期44卷 568-577页

作者： fen WANG Xiao-ling ZHANG Jing ZHANG Song GONG Jing TAO Hui XIANG Xiao-qing fu Xu-na BIAN Xue-feng YU An-hui XU Cheng-la YI Shi-ying SHAO Department of Endocrinology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China Branch of National Clinical Research Center for Metabolic Diseases Wuhan430030China Department of Radiology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China Department of Trauma Surgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China

Objective Diabetic foot ulcer(Dfu)is one of the most serious complications of ***-and platelet-rich fibrin(L-PRF)is a second-generation autologous platelet-rich *** study aims to investigate the clinical effects of L-PRF in patients with diabetes in real clinical *** Patients with Dfu who received L-PRF treatment and standard of care(SOC)from 2018 to 2019 in Tongji Hospital were *** clinical information including patient characteristics,wound evaluation(area,severity,infection,blood supply),SOC of Dfu,and images of ulcers was retrospectively extracted and analyzed.L-PRF treatment was performed every 7±2 days until the ulcer exhibited complete epithelialization or an overall percent volume reduction(PVR)greater than 80%.Therapeutic effectiveness,including overall PVR and the overall and weekly healing rates,was *** Totally,26 patients with Dfu were enrolled,and they had an ulcer duration of 47.0(35.0,72.3)*** severity and infection of ulcers varied,as indicated by the Site,Ischemia,Neuropathy,Bacterial Infection,and Depth(SINBAD)scores of 2–6,Wagner grades of 1–4,and the Perfusion,Extent,Depth,Infection and Sensation(PEDIS)scores of 2–*** initial ulcer volume before L-PRF treatment was 4.94(1.50,13.83)cm3,and the final ulcer volume was 0.35(0.03,1.76)*** median number of L-PRF doses was 3(2,5).A total of 11 patients achieved complete epithelialization after the fifth week of treatment,and 19 patients achieved at least an 80%volume reduction after the seventh *** overall wound-healing rate was 1.47(0.63,3.29)cm3/week,and the healing rate was faster in the first 2 weeks than in the remaining *** treatment did not change the percentage of complete epithelialization or healing *** Adding L-PRF to SOC significantly improved wound healing in patients with Dfu independent of the ankle brachial index,SINBAD score,or Wagner grade,indicating that this method is appropriate for D

关键词： diabetic foot ulcer autologous platelet-rich plasma leukocyte-and platelet-rich fibrin standard of care percentage volume reduction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

恶性胸膜间皮瘤靶向治疗的研究进展

引用

中国肺癌杂志 2024年第5期27卷 391-398页

作者：傅芬张扬沈红南京医科大学第二附属医院呼吸与危重症医学科南京210011

恶性胸膜间皮瘤(malignant pleural mesothelioma, MPM)是侵袭性极强的罕见胸膜表面恶性肿瘤,危险因素包括吸入石棉、遗传因素、基因突变等。现有的化疗、抗血管生成治疗、免疫治疗的效果均不佳,患者的生存期极短。亟需寻找治疗MPM的潜... 详细信息

恶性胸膜间皮瘤(malignant pleural mesothelioma, MPM)是侵袭性极强的罕见胸膜表面恶性肿瘤,危险因素包括吸入石棉、遗传因素、基因突变等。现有的化疗、抗血管生成治疗、免疫治疗的效果均不佳,患者的生存期极短。亟需寻找治疗MPM的潜在靶点,目前发现有基因突变靶点如BRCA1相关蛋白1(BRCA associated protein1, BAP1)和细胞周期蛋白依赖性激酶抑制剂2A(cyclin-dependent kinase 2A, CDKN2A)等;表观遗传靶点如组蛋白赖氨酸去甲基酶4A[lysine (K)-specific demethylase 4A, KDM4A]和赖氨酸特异性去甲基酶1(lysine-specific demethylase1, LSD1)等;信号蛋白靶点如葡萄糖调节蛋白78(glucose-regulated protein 78, GRP78)及信号转导和转录激活因子3(signal transducer and activator of transcription 3, STAT3)等。迄今为止,可查询的临床试验有组蛋白甲基转移酶抑制剂Tazemetostat、多聚ADP-核糖聚合酶[poly (ADP-ribose) polymerase, PARP]抑制剂Rucaparib和细胞周期蛋白依赖性激酶4/6(cyclin-dependent kinases 4 and 6, CDK4/6)抑制剂Abemaciclib的II期临床试验,以及靶向间皮素的嵌合抗原受体T细胞免疫疗法(chimeric antigen receptor T-cell immunotherapy, CAR-T)细胞胸腔注射、TEA结构域家族成员(TEA domain family member, TEAD)抑制剂VT3989和IK-930的I期临床试验,显示出一定的临床疗效。

关键词：恶性胸膜间皮瘤基因突变表观遗传信号蛋白靶向治疗

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

基于W几何形的恒星光谱分子带检测

引用

光谱学与光谱分析 2024年第8期44卷 2279-2283页

作者：陈奋王颖刘福窑上海工程技术大学数理与统计学院上海201620 上海工程技术大学计算物理与应用研究中心上海201620

研究关注由分子内部能级变化引起的光谱分子带的识别和检测,有助于研究恒星光谱类型和参数估计。首先从分子带的曲线趋势出发,运用曲线分析对分子带进行识别,并剔除具备W形但下降趋势明显的伪分子带。借鉴多类型多分类准则的识别思路,... 详细信息

研究关注由分子内部能级变化引起的光谱分子带的识别和检测,有助于研究恒星光谱类型和参数估计。首先从分子带的曲线趋势出发,运用曲线分析对分子带进行识别,并剔除具备W形但下降趋势明显的伪分子带。借鉴多类型多分类准则的识别思路,将检测出的分子带尖峰深度、W形宽度、曲线趋势和回升趋势四个参数作为训练特征。这四个参数综合考虑了始点变化速率、曲线变化趋势、极值点分布和曲线形状因素。其次,为了验证该方法的可行性与可靠性,利用LightGBM(light gradient boosting machine)模型分别对F型恒星光谱和分子带特征参数进行识别,准确率分别为97.62%和99.16%,进一步验证了所提取分子带的准确性。本工作不仅能挖掘出晚期恒星,提高数据标签的准确性,还能在准确识别的基础上,利用LightGBM机器学习模型检测未知型光谱自动识别晚期恒星,提高了识别效率并且减少了内存占用。

关键词： W几何形特征分子带检测曲线趋势分类识别恒星光谱

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Safety and efficacy of peroral endoscopic myotomy for treating achalasia in pediatric and geriatric patients:A

引用

World Journal of Gastrointestinal Endoscopy 2024年第10期16卷 566-580页

作者： Xin-Xin Pu Shu Huang Chun-Yu Zhong Xia Wang Su-fen.fu Ying-Qin Lv Kang Zou Mu-Han Lü Yan Peng Xiao-Wei Tang Department of Gastroenterology Dechang People’s Hospital of Sichuan ProvinceLiangshan 615500Sichuan ProvinceChina Department of Gastroenterology The Affiliated Hospital of Southwest Medical UniversityLuzhou 646000Sichuan ProvinceChina Department of Gastroenterology Lianshui People’s Hospital of Kangda College Affiliated to Nanjing Medical UniversityHuaian 223499Jiangsu ProvinceChina Department of Ultrasound The Affiliated Hospital of Southwest Medical UniversityLuzhou 646000Sichuan ProvinceChina

BACKGROUND As a less invasive technique,peroral endoscopic myotomy(POEM)has recently been widely accepted for treating achalasia with an excellent safety profile,durability,and efficacy in *** pediatric and geriatric patients,the treatment is more *** To discuss the clinical outcomes of POEM in pediatric and geriatric patients with *** We conducted a comprehensive search of PubMed,Embase and Cochrane Library databases from inception to July *** primary outcomes were technical and clinical *** outcomes of interest included adverse events and gastroesophageal reflux disease(GERD).The pooled event rates were calculated by comprehensive meta-analysis *** A total of 32 studies with 547 pediatric patients and 810 geriatric patients were included in this *** pooled event rates of technical success,clinical success,GERD and adverse events of POEM for treating achalasia in pediatric patients were 97.1%[95%confidence interval(CI):95.0%-98.3%;I²=0%;P<0.000],93.2%(95%CI:90.5%-95.2%;I²=0%;P<0.000),22.3%(95%CI:18.4%-26.7%;I²=43.874%;P<0.000)and 20.4%(95%CI:16.6%-24.8%;I²=67.217%;P<0.000),***,in geriatric patients,the pooled event rates were 97.7%(95%CI:95.8%-98.7%;I²=15.200%;P<0.000),93.2%(95%CI:90.3%-95.2%;I²=0%;P<0.000),23.9%(95%CI:19.4%-29.1%;I²=75.697%;P<0.000)and 10.8%(95%CI:8.3%-14.0%;I²=62.938%;P<0.000],*** Our findings demonstrated that POEM was an effective and safe technique for pediatric and geriatric patients with achalasia.

关键词： Achalasia Peroral endoscopic myotomy Pediatric Geriatric Meta-analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Perspectives of genetic management strategy for inherited cardiovascular diseases in China

引用

Chinese Medical Journal 2024年第8期137卷 959-961页

作者： Yaoyao Zhang Yanjiang Zheng Mengyuan Dai Kaiyu Zhou Lijun fu Yuxuan Guo Yihua He fen Li Rui Gao Donghui Zhang Xujie Liu Jie Tian Yimin Hua Yifei Li Lang Qin Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE West China Second University HospitalSichuan UniversityChengduSichuan 610041China Department of Department of Obstetrics and Gynecology West China Second University HospitalSichuan UniversityChengduSichuan 610041China Department of Pediatrics West China Second University HospitalSichuan UniversityChengduSichuan 610041China Department of Cardiology Shanghai Children’s Medical CenterSchool of MedicineShanghai Jiao Tong UniversityShanghai 200025China Peking University Health Science Center School of Basic Medical SciencesThe Institute of Cardiovascular SciencesKey Laboratory of Molecular Cardiovascular Science of Ministry of EducationBeijing 100191China Department of Ultrasound Beijing Anzhen Hospital affiliated to Capital Medical UniversityBeijing 100029China State Key Laboratory of Biocatalysis and Enzyme Engineering School of Life ScienceHubei UniversityWuhanHubei 430062China Shenzhen Key Laboratory of Cardiovascular Disease Fuwai Hospital Chinese Academy of Medical SciencesShenzhenGuangdong 518052China Department of Cardiology Ministry of Education Key Laboratory of Child Development and DisordersNational Clinical Research Center for Child Health and Disorders(Chongqing)China International Science and Technology Cooperation Base of Child Development and Critical DisordersChildren’s Hospital of Chongqing Medical UniversityChongqing 400014China

Inherited cardiovascular diseases(CVDs)threaten human health and pose an enormous economic burden *** alteration is a major risk factor for many *** disorders are usually controlled by a pair of alleles,affecting offspring according to the Mendelian principle,regardless of isolated primary damage or secondary injury from other syndromes or *** date,there are hundreds of inherited *** advances in nextgeneration sequencing(NGS)technologies,rapid and accurate molecular diagnosis of patients with inherited CVDs is clinically ***,great improvements have been made in recent years,and targeted therapy and assist devices have been used in clinical *** there is still no totally efficient strategy for dealing with inherited ***.

关键词： diagnosis hundreds dealing

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

不同海域野生海参体壁营养成分的比较分析

引用

食品工业科技 2024年第5期45卷 341-348页

作者：王长伟冯晓梅刘楚怡付雪媛杜芬青岛海洋生物医药研究院山东青岛266071 三奇生物医药(山东)有限公司山东日照276800 中国海洋大学医药学院山东青岛266003

探究不同海域野生海参的营养功能成分,为野生海参的综合开发利用提供参考,本文对糙刺参、黄玉参、土耳其米刺参以及冰岛红参等四种海参体壁中基本营养成分、氨基酸组成、脂肪酸组成、矿物质含量等进行检测、分析和评价。结果表明,四种... 详细信息

探究不同海域野生海参的营养功能成分,为野生海参的综合开发利用提供参考,本文对糙刺参、黄玉参、土耳其米刺参以及冰岛红参等四种海参体壁中基本营养成分、氨基酸组成、脂肪酸组成、矿物质含量等进行检测、分析和评价。结果表明,四种海参的共同点为高蛋白、低脂肪。其中,土耳其米刺参蛋白含量最高,脂肪含量最低;黄玉参的海参多糖和灰分含量均最高;冰岛红参的海参皂苷含量最高。四种海参均含有17种氨基酸,且鲜味氨基酸与药效氨基酸含量丰富;必需氨基酸含量占比13.78%~20.27%,其中冰岛红参的必需氨基酸含量最高。根据氨基酸评分(AAS)和化学评分(CS),四种海参的第一限制性氨基酸均为赖氨酸。四种海参的SFA占总脂肪酸的质量分数在23.84%~36.24%之间,均以棕榈酸(C16:0)和硬脂酸(C18:0)为主;不饱和脂肪酸占比在56.39%~72.93%之间,其中冰岛红参含量最高。在四种海参的常量元素中,除土耳其米刺参以外,其余三种海参均以钙元素含量最高,微量元素中,含量最高的均是铁元素。通过比较分析表明:不同海域野生海参富含人体需要的多种营养,具有不同的食用价值和开发利用前景。

关键词：海参营养成分氨基酸脂肪酸矿物质不同海域

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

海上风机支撑结构承载性能试验研究

引用

武汉理工大学学报（交通科学与工程版） 2024年第1期48卷 50-54页

作者：李芬陈嘉辉杨宇付娇娇武汉理工大学船海与能源动力工程学院武汉430063 中交武汉港湾工程设计研究院有限公司武汉430040

基于波流水槽开展的模型试验,设计了风机支撑结构受到水流、循环荷载、无水和静水环境条件等工况,获得了单向流作用、循环荷载作用以及单向流与循环荷载共同作用等不同荷载组合下风机支撑结构的承载性能.结果表明:循环荷载作用下风机支... 详细信息

基于波流水槽开展的模型试验,设计了风机支撑结构受到水流、循环荷载、无水和静水环境条件等工况,获得了单向流作用、循环荷载作用以及单向流与循环荷载共同作用等不同荷载组合下风机支撑结构的承载性能.结果表明:循环荷载作用下风机支撑结构在无水条件下的产生的累积位移是静水条件下的46.12%,单向流和循环荷载共同作用时,支撑结构累积位移较单独荷载作用效果叠加时增加了60.84%.在有水的环境和多种荷载共同作用下,风机支撑结构承载性能有明显降低,因此,在海上风机结构设计和安全评估时应考虑多种荷载共同作用的影响.

关键词：海上风机支撑结构模型试验循环荷载承载性能

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

泥炭质土非线性固结理论研究

引用

公路交通科技 2024年第2期41卷 69-78页

作者：阮永芬张福禄乔文件吴龙谈燕昆明理工大学建筑工程学院云南昆明650500 中铁二十局集团第五工程有限公司云南昆明650000 中铁十一局集团城市轨道工程有限公司湖北武汉430074 云南省科仑工程质量检测有限公司云南昆明650228

在泥炭质土软基固结过程中,孔隙比和渗透系数会随固结时间增加逐渐变小,导致按Terzaghi一维固结理论计算的软基固结值与实测值存在较大误差,故以滇池湖相沉积泥炭质土为研究对象,进行固结-渗透联合试验,研究泥炭质土e-σ′,k-σ′之间规... 详细信息

在泥炭质土软基固结过程中,孔隙比和渗透系数会随固结时间增加逐渐变小,导致按Terzaghi一维固结理论计算的软基固结值与实测值存在较大误差,故以滇池湖相沉积泥炭质土为研究对象,进行固结-渗透联合试验,研究泥炭质土e-σ′,k-σ′之间规律,从而得到e-lgσ′,lgk-lgσ′模型,然后引入这两个模型推导出适用于泥炭质土的一维非线性固结理论,并求解出渗压指数C_(k)=1,C_(k)=2两种不同条件下的解析解。根据所取泥炭质土的C_(k)不同,当C_(k)=1时,一维非线性固结微分方程的解析解与Terzaghi一维固结方程解析解比较,仅竖向固结系数存在差异;当C_(k)=2时,一维非线性固结微分方程难以直接得到解析解,可引入激活函数得到非线性固结微分方程的一个特解。研究发现,C_(k)=1时,泥炭质土固结过程中Terzaghi一维固结理论预测沉降速率比实测快,固结完成所需时间短;推导的一维非线性固结理论预测的各时间段固结沉降值和实测值接近,预测固结完成所需的时间误差小,且上覆荷载越大St-t关系曲线与实测值越接近,推导的一维非线性固结理论预测结果越精确。研究结果可为泥炭质土类软基提供一种更为精确的固结计算方法。

关键词：道路工程非线性固结理论固结-渗透联合试验泥炭质土土力学渗透系数

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：