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Myocardial Perfusion Abnormalities in Patients with Hereditary Hypertrophic Cardiomyopathy: A Study of Three Cases and Review of the Literature

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World Journal of Cardiovascular Diseases 2023年第6期13卷 289-296页

作者： Ngardjibem Djita Ibrahima Sory Sylla Mamadou Bassirou Bah felix collard Sana Samoura Mamadou Aliou Baldé Souleymane Diakité Ibrahima Sory Barry Alpha Koné Elhadj Yaya Baldé Mariame Béavogui Mamadou Dadhi Baldé Philippe Chevalier Department of Cardiology Alen&ccedilon Hospital Alen&ccedilon France Department of Cardiology CHU Ignace Deen Conakry Guinea Department of Cardiology Sino-Guinean Friendship Hospital Conakry Guinea Department of Cardiology CHU Lyon Lyon France

Introduction: Hypertrophic cardiomyopathy (HCM) belongs to the very heterogeneous group of cardiomyopathies. This study aimed to study myocardial perfusion abnormalities on scintigraphy and assess the risk of sudden death from ventricular arrhythmia in hereditary sarcomeric HCM. Patients and Methods: This is a retrospective and prospective descriptive study over 18 months (January 01, 2021, to July 31, 2022) on the records of patients over 18 with the diagnosis of hypertrophic sarcomeric cardiomyopathy with or without ventricular rhythm disorders and who have undergone myocardial scintigraphy. Results: Three patients were included. The average age of our patients was 66 years old. Dyspnea is the primary symptomatology found in our patients. One patient presented with syncope and unsustained ventricular tachycardia. His risk score for sudden death from ESC at five years is estimated at 6.45%, and the patient received an ICD in primary prevention. The average sudden death risk score of our patients was 3.78%. The mean LV wall thickness was 20 mm. The mean maximum left intraventricular gradient was 39 mmHg. Myocardial fibrosis was present in all our patients. Myocardial scintigraphy was normal in all cases. Conclusion: Hypertrophic cardiomyopathy is a very heterogeneous group of cardiomyopathies. The rhythmic risk is multifactorial and constitutes a significant prognostic factor.

关键词： Hypertrophic Cardiomyopathy Myocardial Scintigraphy Sudden Death Ven-tricular Arrhythmia

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Plastic ingestion and associated additives in Faroe Islands chicks of the Northern Fulmar Fulmarus glacialis

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Water Biology and Security 2022年第4期1卷 68-76页

作者： France collard Simon Leconte Johannis Danielsen Claudia Halsband Dorte Herzke Mikael Harju felix Tulatz Geir W.Gabrielsen Arnaud Tarroux Norwegian Polar Institute Fram Centre for Climate and the EnvironmentFram CentreN-9296TromsøNorway Norwegian Institute for Nature Research Fram Centre for Climate and the EnvironmentFram CentreN-9296TromsøNorway Faroe Marine Research Institute 100TorshavnFaroe Islands Akvaplan-niva Fram Centre for Climate and the EnvironmentFram CentreN-9296TromsøNorway The Norwegian Institute for Air Research Fram Centre for Climate and the EnvironmentN-9296TromsøNorway

Northern Fulmars(Fulmarus glacialis)are a pelagic seabird species distributed at northern and polar *** are often used as an indicator of plastic pollution in the North Sea region,but data are lacking from higher latitudes,especially when it comes to ***,we investigated amounts of ingested plastic and their characteristics in fulmar chicks from the Faroe *** particles(≥1 mm)in chicks of two age classes were searched using a digestion method with *** addition,to evaluate if additive tissue burden reflects plastic ingestion,we measured liver tissue concentrations of two pollutant classes associated with plastic materials:polybrominated diphenyl ethers(PBDEs)and several dechloranes,using gas chromatography with high-resolution mass *** most common shape was hard fragment(81%)and the most common polymer was polyethylene(73%).Plastic contamination did not differ between either age class,and we found no correlation between neither the amount and mass of plastic particles and the concentration of *** comparison with previous studies on adult fulmars,we do not recommend using chicks for biomonitoring adults because chicks seem to ingest more plastics than adults.

关键词： Plastic pollution PBDE Dechlorane Arctic Early life stage Monitoring Seabird

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