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World Journal of Cardiovascular Surgery 2011年第2期1卷 18-23页

作者： Jean-Francois Morin Berguez Mistry Yves Langlois felix ma Patrick Chamoun Christina Holcroft Cardiac Surgery SMBD Jewish General HospitalMcGillMontrealCanada Anesthesia SMBD Jewish General HospitalMcGillMontrealCanada Clinical Epidemiology and Public Health Research Center Jewish General HospitalMcGillMontrealCanada

This study is a prospective trial comparing the incidence of post-operative complications to fluid status in patients undergoing coronary artery bypass grafting (CABG) surgery. One hundred and nine subjects undergoing CABG surgery at the Jewish general hospital were recruited over a 5 months period in the year 2006. All of the patients underwent CABG surgery “on pump”. Post operative fluid overload was measured by weight gain. Using logistic regression with complications (major vs. minor only/none) as an outcome and fluid overload as a covariate, the risk of major complications significantly increases for fluid overload ≥5 kg compared to 1 - 5 kg (p major complications significantly (p = 0.012) increases for days with fluid overload ≥5 days in comparison to ≤1 day.

关键词： Fluid Overload Complications Coronary Artery Bypass Grafting

Room Temperature Synthesis of Vertically Aligned Amorphous Ultrathin NiCo-LDH Nanosheets Bifunctional Flexible Supercapacitor Electrodes

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Energy & Environmental materials 2024年第2期7卷 277-286页

作者： Kwadwo Asare Owusu Zhaoyang Wang Ali Saad felix Ofori Boakye Muhammad Asim Mushtaq Muhammad Tahir Ghulam Yasin Dongqing Liu Zhengchun Peng Xingke Cai Institute for Advanced Study Shenzhen UniversityShenzhen 518060China College of Physics and Optoelectronics Shenzhen University3688 Nanhai BoulevardNanshan DistrictShenzhen 518060China School of Chemistry and materials Science Hubei Engineering UniversityNo.272 Traffic AvenueXiaogan 432000China State Key Laboratory of Advanced Technology for materials Synthesis and Processing Wuhan University of TechnologyNo.122 Luoshi RoadWuhan 430070China Key Laboratory of Green Printing CAS Research Centre for Excellence in Molecular ScienceInstitute of Chemistry Chinese Academy of Sciences(ICCAS)Beijing 100190China College of Mechatronics and Control Engineering Shenzhen University3688 Nanhai BoulevardNanshan DistrictShenzhen 518050China

Developing a simple scalable method to fabricate electrodes with high capacity and wide voltage range is desired for the real use of electrochemical ***,we synthesized amorphous NiCo-LDH nanosheets vertically aligned on activated carbon cloth substrate,which was in situ transformed from Co-metal-organic framework materials nano-columns by a simple ion exchange process at room *** to the amorphous and vertically aligned ultrathin structure of NiCo-LDH,the NiCo-LDH/activated carbon cloth composites present high areal capacities of 3770 and 1480 mF cm^(-2)as cathode and anode at 2 ma cm^(-2),and 79.5%and 80%capacity have been preserved at 50 ma cm^(-2).In the meantime,they all showed excellent cycling performance with negligible change after>10000 *** fabricating them into an asymmetric supercapacitor,the device achieves high energy densities(5.61 mWh cm^(-2)and 0.352 mW cm^(-3)).This work provides an innovative strategy for simplifying the design of supercapacitors as well as providing a new understanding of improving the rate capabilities/cycling stability of NiCo-LDH materials.

关键词： amorphous nanosheets aqueous supercapacitor high volumetric/areal energy density NiCo-LDH room temperature synthesis

Effect of surface damage induced by cavitation erosion on pitting and passive behaviors of 304L stainless steel

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International Journal of Minerals,Metallurgy and materials 2023年第7期30卷 1338-1352页

作者： Liang Li Yanxin Qiao Lianmin Zhang Aili ma Enobong felix Daniel Rongyao ma Jian Chen Yugui Zheng School of materials Science and Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China CAS Key Laboratory of Nuclear materials and Safety Assessment Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China Shenyang National Research Center for materials Science Institute of MetalsChinese Academy of SciencesShenyang 110016China

The corrosion behavior of 304L stainless steel(SS)in 3.5wt%NaCl solution after different cavitation erosion(CE)times was mainly evaluated using electrochemical noise and potentiostatic polarization *** was found that the antagonism effect resulting in the passivation and depassivation of 304L SS had significant distinctions at different CE *** passive behavior was predominant during the incubation period of CE where the metastable pitting initiated at the surface of 304L *** the rising period of CE,the 304L SS experienced a transition from passivation to depassivation,leading to the massive growth of metastable pitting and stable *** depassivation of304L SS was found to be dominant at the stable period of CE where serious localized corrosion occurred.

关键词： cavitation erosion pitting stainless steel electrochemical noise

Effects of rare earth modifying inclusions on the pitting corrosion of 13Cr4Ni martensitic stainless steel

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Journal of materials Science & Technology 2021年第34期93卷 232-243页

作者： Changgang Wang Rongyao ma Yangtao Zhou Yang Liu Enobong felix Daniel Xiaofang Li Pei Wang Junhua Dong Wei Ke Shenyang National Laboratory for materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China University of Chinese Academy of Sciences Beijing 100049China Environmental Corrosion Centre of materials Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China

In this study,the pitting corrosion behavior of 13Cr4Ni martensitic stainless steel(BASE)and that modified with rare earth(REM)in 0.1 mol/L Na Cl solution were *** such as automatic secondary electron microscope(ASPEX PSEM detector),scanning electron microscope(SEM),transmission electron microscope(TEM),scanning Kelvin probe force microscope(SKP),potentiodynamic and potentiostatic polarizations were *** results obtained indicate that BASE steel contains Al_(2)O_(3)/Mn S,Al_(2)O_(3) and Mn S inclusions,while REM steels contain(La,Ce,Cr,Fe)-O and(La,Ce,Cr,Fe)-O-S *** with BASE steel,REM steel is more susceptible to induce the metastable pitting nucleation and repassivation,whereas it restrains the transition from metastable pitting to stable *** 0.021%rare earth element to BASE steel can reduce the number and area of inclusions,while that of 0.058%can increase the number and enlarged the size of inclusions,which is also the reason that pitting corrosion resistance of 58 REM steel is slightly lower than that of 21 REM *** the process of pitting corrosion induced by Al_(2)O_(3)/Mn S inclusions,Mn S is preferentially anodic dissolved,and also the matrix contacted with Al_(2)O_(3) is subsequently anodic *** REM steels,anodic dissolution preferentially occurs at the boundary between inclusions and matrix,while(La,Ce,Cr,Fe)-O inclusions chemically dissolve in local acidic environment or are separated from steel *** chemically dissolved substance(La^(3+) and Ce^(3+))of(La,Ce,Cr,Fe)-O inclusions are concentrated in pitting pits,which inhibits its continuous growth.

关键词： 13Cr4Ni martensitic stainless steel Rare earth modifying inclusion Al_(2)O_(3)/MnS inclusion Metastable pitting corrosion Stable pitting corrosion

Corrosion Behaviour of Carbon Steel Fasteners in Neutral Chloride Solution

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Acta Metallurgica Sinica(English Letters) 2022年第4期35卷 563-576页

作者： Enobong felix Daniel Junhua Dong Xiaofang Li Ini-Ibehe Nabuk Etim Inime Ime Udoh Rongyao ma Lei Chen Changgang Wang Shenyang National Laboratory for materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of materials Science and Engineering University of Science and Technology of ChinaShenyang 110016China School of materials Science and Engineering Northeastern UniversityShenyang 110819China School of Environmental and Chemical Engineering Shenyang Ligong UniversityShenyang 110159China Department of marine Biology Akwa Ibom State UniversityP.M.B 1167UyoNigeria

An experimental model for simulating the corrosion of carbon steel fasteners(bolt and nut) composed of a contact carbon steel electrode(CCSE) and an exposed bare carbon steel plate electrode(BCSE) was designed. The effect of coupling on the corrosion process of the galvanically coupled carbon steel electrode was evaluated and compared with the self-corrosion process observed independently at the exposed and contact regions. Results obtained indicated that at an equal area ratio and uncoupled conditions, the corrosion rate is accelerated in the surface directly exposed to bulk solution compared to the bolt surface in contact with the nut. A coupling current was recorded when the exposed surface(BCSE) was electrically connected with the contact surface(CCSE);with the CCSE acting as the anode thereby suppressing the corrosion process in the exposed surface. By implication, the galvanic coupling between CCSE and BCSE increased the corrosion rate of CCSE. The diff erence in oxygen supply was responsible for the coupling effect observed in the system as there was no decrease in the solution pH. Moreover, varying the cathode-to-anode area( S c/S a) ratio significantly influenced the corrosion current density as increased S c/S a ratio resulted in an accelerated galvanic corrosion process. The corroded surfaces and interfaces were analysed using stereomicroscopy and scanning electron microscopy. X-ray diff ractometry was adopted for corrosion product characterization. The results obtained showed supportive evidence of the corrosion behaviour in carbon steel fasteners.

关键词： Bolt and nut Galvanic current density Zero resistance ammetry(ZRA) Coupling potential Differential aeration cell Carbon steel fasteners

The interplay between (electro)chemical and (chemo)mechanical effects in the cycling performance of thiophosphate-based solid-state batteries

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materials Futures 2022年第1期1卷 122-134页

作者： Jun Hao Teo Florian Strauss felix Walther Yuan ma Seyedhosein Payandeh Torsten Scherer matteo Bianchini Jürgen Janek Torsten Brezesinski Battery and Electrochemistry Laboratory Institute of NanotechnologyKarlsruhe Institute of Technology(KIT)Hermann-von-Helmholtz-Platz 176344 Eggenstein-LeopoldshafenGermany Institute of Physical Chemistry&Center for materials Research Justus-Liebig-University GiessenHeinrich-Buff-Ring 1735392 GiessenGermany KNMF Laboratory for Micro-and Nanostructuring Institute of NanotechnologyKarlsruhe Institute of Technology(KIT)Hermann-von-Helmholtz-Platz 176344 Eggenstein-LeopoldshafenGermany BASF SE Carl-Bosch-Str.3867056 LudwigshafenGermany

Solid-state batteries(SSBs)are a promising next step in electrochemical energy storage but are plagued by a number of *** this study,we demonstrate the recurring issue of mechanical degradation because of volume changes in layered Ni-rich oxide cathode materials in thiophosphate-based ***,we explore superionic solid electrolytes(SEs)of different crystallinity,namely glassy 1.5Li_(2)S-0.5P_(2)S_(5)-LiI and argyrodite Li_(6)PS_(5)Cl,with emphasis on how they affect the cyclability of slurry-cast cathodes with NCM622(60%Ni)or NCM851005(85%Ni).The application of a combination of ex situ and in situ analytical techniques helped to reveal the benefits of using a SE with a low Young’s *** a synergistic interplay of(electro)chemical and(chemo)mechanical effects,the glassy SE employed in this work was able to achieve robust and stable interfaces,enabling intimate contact with the cathode material while at the same time mitigating volume *** results emphasize the importance of considering chemical,electrochemical,and mechanical properties to realize long-term cycling performance in high-loading SSBs.

关键词： solid-state battery slurry casting lithium thiophosphate electrolyte Ni-rich NCM cathode degradation

Temporal gradients limit the accumulation of neutrophils toward sources of chemoattractant

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Microsystems & Nanoengineering 2017年第1期3卷 455-462页

作者： Arvind Chandrasekaran felix Ellett Julianne Jorgensen Daniel Irimia Department of Surgery BioMEMS Resource CenterMassachusetts General HospitalHarvard Medical SchoolShriners Burns HospitalBostonMA 02129USA

Neutrophil trafficking during inflammation is a highly orchestrated process,coordinating neutrophil recruitment,sterilization of the wound,and inflammation *** the chemotactic signals guiding neutrophil recruitment to sites of inflammation are relatively well understood,our knowledge of mechanisms controlling cessation of neutrophil recruitment and return to normal tissue physiology remains *** gain insights into these processes,we designed a microfluidic device with an array of chemoattractant reservoirs,which mimics the microenvironment in infected tissues,when multiple clusters of microbes are *** monitored the temporal dynamics of neutrophil recruitment toward the chemoattractant reservoirs at single cell resolution,for 3 *** observed robust neutrophil recruitment that reached a plateau after 1.5 h,despite the continuous presence of strong chemoattractant gradients around the *** timing of the plateau was dependent on the geometry of the devices and was independent from the number of *** the basis of these observations,we ruled out sub-population sensitivity,chemoattractant scavenging,and production of a self-limiting stop signal as potential mechanisms underpinning the plateau in neutrophil *** found a strong correlation between the temporal stabilization of concentration changes and the plateau in neutrophils *** results suggest that dynamic aspects of chemoattractant gradients are key for maximizing recruitment during the acute phase of infections and limiting the accumulation of neutrophils as soon as the infection is contained.

关键词： chemotaxis leukocyte microfluidic relay signaling scavenging

RhizoVision Crown:An Integrated Hardware and Software Platform for Root Crown Phenotyping

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Plant Phenomics 2020年第1期2卷 25-39页

作者： Anand Seethepalli Haichao Guo Xiuwei Liu marcus Griffiths Hussien Almtarfi Zenglu Li Shuyu Liu Alina Zare felix B.Fritschi Elison B.Blancaflor Xue-Feng ma Larry M.York Noble Research Institute LLC2510 Sam Noble ParkwayArdmoreOK 73401USA Division of Plant Sciences University of MissouriColumbiaMO 65201USA Crop and Soil Sciences University of GeorgiaAthensGA 30602USA Texas A&M AgriLife Research Texas A&M University SystemAmarilloTX 79106USA Department of Electrical and Computer Engineering University of FloridaGainesvilleFL 32601USA

Root crown phenotyping measures the top portion of crop root systems and can be used for marker-assisted breeding,genetic mapping,and understanding how roots influence soil resource *** imaging protocols and image analysis programs exist,but they are not optimized for high-throughput,repeatable,and robust root crown *** RhizoVision Crown platform integrates an imaging unit,image capture software,and image analysis software that are optimized for reliable extraction of measurements from large numbers of root *** hardware platform utilizes a backlight and a monochrome machine vision camera to capture root crown *** RhizoVision Imager and RhizoVision Analyzer are free,open-source software that streamline image capture and image analysis with intuitive graphical user *** RhizoVision Analyzer was physically validated using copper wire,and features were extensively validated using 10,464 groundtruth simulated images of dicot and monocot root *** platform was then used to phenotype soybean and wheat root crowns.A total of 2,799 soybean(Glycine max)root crowns of 187 lines and 1,753 wheat(Triticum aestivum)root crowns of 186 lines were *** component analysis indicated similar correlations among features in both *** maximum heritability was 0.74 in soybean and 0.22 in wheat,indicating that differences in species and populations need to be *** integrated RhizoVision Crown platform facilitates high-throughput phenotyping of crop root crowns and sets a standard by which open plant phenotyping platforms can be benchmarked.

关键词： crown utilize intuitive

Argon preconditioning protects neuronal cells with a Toll-like receptor-mediated effect

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Neural Regeneration Research 2023年第6期18卷 1371-1377页

作者： Stefanie Scheid Adrien Lejarre Jakob Wollborn Hartmut Buerkle Ulrich Goebel felix Ulbrich Department of Anesthesiology and Critical Care Medical Center-University of FreiburgFaculty of MedicineFreiburgGermany Department of Anesthesiology Perioperative and Pain MedicineBrigham and Women’s HospitalHarvard Medical SchoolBostonMAUSA Department of Anesthesiology and Critical Care Medicine St.Franziskus-HospitalMuensterGermany

The noble gas argon has the potential to protect neuronal cells from cell *** far,this effect has been studied in treatment after acute *** using argon has not yet been *** this study,human neuroblastoma SH-SY5Y cells were treated with different concentrations of argon(25%,50%,and 74%;21%O_(2),5%CO_(2),balance nitrogen)at different time intervals before inflicting damage with rotenone(20μM,4 hours).Apoptosis was determined by flow cytometry after annexin V and propidium iodide *** expressions of Toll-like receptors 2 and 4 were also *** were also processed for analysis by western blot and qPCR to determine the expression of apoptotic and inflammatory proteins,such as extracellular-signal regulated kinase(ERK1/2),nuclear transcription factor-κB(NF-κB),protein kinase B(Akt),caspase-3,Bax,Bcl-2,interleukin-8,and heat shock *** staining was performed for TLR2 and 4 and *** were also pretreated with OxPAPC,an antagonist of TLR2 and 4 to elucidate the molecular *** showed that argon preconditioning before rotenone application caused a dose-dependent but not a time-dependent reduction in the number of apoptotic *** with 74%argon for 2 hours was used for further experiments showing the most promising *** decreased the surface expression of TLR2 and 4,whereas OxPAPC treatment partially abolished the protective effect of *** increased phosphorylation of ERK1/2 but decreased NF-κB and *** inhibited mitochondrial apoptosis and the heat shock *** also suppressed the expression of the pro-inflammatory cytokine *** confirmed the alteration of TLRs and *** reversed the argon effect on ERK1/2,Bax,Bcl-2,caspase-3,and interleukin-8 expression,but not on NF-κB and the heat shock *** together,argon preconditioning protects against apoptosis of neuronal c

关键词： apoptosis inflammation interleukin-8 neuroprotection rotenone SH-SY5Y Toll-like receptor 2 Toll-like receptor 4

miRNA sequencing analysis of healthy and atretic follicles of chickens revealed that miR-30a-5p inhibits granulosa cell death via targeting Beclin1

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Journal of Animal Science and Biotechnology 2022年第5期13卷 1351-1372页

作者： Haorong He Dongmei Li Yongtong Tian Qinyao Wei felix Kwame Amevor Congjiao Sun Chunlin Yu Chaowu Yang Huarui Du Xiaosong Jiang Menggen ma Can Cui Zhichao Zhang Kai Tian Yao Zhang Qing Zhu Huadong Yin Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province Sichuan Agricultural UniversityChengdu 611130SichuanChina National Engineering Laboratory for Animal Breeding and Key Laboratory of Animal Genetics Breeding and ReproductionMinistry of Agriculture and Rural AffairsCollege of Animal Science and TechnologyChina Agricultural UniversityBeijing 100193China Animal Breeding and Genetics key Laboratory of Sichuan Province Sichuan Animal Science AcademyChengdu 610066China College of Resources Sichuan Agricultural UniversityChengdu 611130China

Background:The egg production performance of chickens is affected by many factors,including genetics,nutrition and environmental *** factors all play a role in egg production by affecting the development of ***(miRNAs)are important non-coding RNAs that regulate biological processes by targeting genes or other non-coding RNAs after *** the animal reproduction process,miRNA is known to affect the development and atresia of follicles by regulating apoptosis and autophagy of granulosa cells(GCs).Results:In this study,we identified potential miRNAs in the atretic follicles of broody chickens and unatretic follicles of healthy *** identified gga-miR-30a-5p in 50 differentially expressed miRNAs and found that gga-miR-30a-5p played a regulatory role in the development of chicken *** function of miR-30a-5p was explored through the transfection test of miR-30a-5p inhibitor and miR-30a-5p *** the study,we used qPCR,western blot and flow cytometry to detect granulosa cell apoptosis,autophagy and steroid hormone *** microscopy and transmission electron microscopy are used for the observation of *** levels of estradiol(E2),progesterone(P4),malondialdehyde(MDA)and superoxide dismutase(SOD)were detected by *** results showed that miR-30a-5p showed a negative effect on autophagy and apoptosis of granulosa cells,and also contributed in steroid hormones and reactive oxygen species(ROS)*** addition,the results obtained from the biosynthesis and dual luciferase experiments showed that Beclin1 was the target gene of *** rescue experiment conducted further confirmed that Beclin1 belongs to the miR-30a-5p regulatory ***:In summary,after deep miRNA sequencing on healthy and atretic follicles,the results indicated that miR-30a-5p inhibits granulosa cell death by inhibiting Beclin1.

关键词： Apoptosis Autophagy Beclin1 Chicken granulosa cells MiR-30a-5p Oxidative stress RNA-seq Steroid hormone