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Surgical Treatment and Prognosis of Synchronous Double Primary Lung Cancer： a Report of 31 Cases

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Chinese Journal of Clinical Oncology 2005年第5期2卷 824-828页

作者： feiyue Feng Dechao zhang Xiangyang Liu Yonggang Wang Yousheng Mao Department of Thoracic Surgery Cancer Hospital/Institute Chinese Academy of Medical Sciences＆Peking Union Medical College Beijing 100021 China.

OBJECTIVE The concept of double primary lung cancer （DPLC） has been generally accepted. Recently, an increasing incidence of synchronous DPLC has been reported, while the diagnostic standard and treatment strategies remain to be improved. This study was conducted to investigate effective surgical treatment and prognosis of synchronous DPLC. METHODS From January 1983 to April 2004, 31 patients with synchronous DPLC were operated in our department. Clinical data, such as surgical pattern, postoperative complications, and survival status, of all these patients were reviewed retrospectively. RESULTS The 31 patients with synchronous DPLC accounted for 0.67% of all the 4,649 patients operated for primary lung cancer in our department during the same period. Both tumors of the synchronous DPLC were resected with Iobectomy or pneumonectomy in 12 patients, while among the other 19 patients at least 1 tumor was treated with partial pulmonary resection. The postoperative morbidity was 29%（9/31）, including 1 case of respiratory insufficiency, 3 cases of atelectasis, 2 cases of atrial fibrillation, 1 case of haemoptysis, 1 case of pleural effusion, and 1 case of wound fat necrosis. No deaths occurred during the operations or within 30 days postoperatively. The postoperative 1 -, 3-, and 5-year survival rates were 52%, 29%, and 20%, respectively. CONCLUSION The incidence of synchronous DPLC is low. An aggressive and reasonable surgical approach can achieve a satisfactory outcome in patients with synchronous DPLC. The postoperative morbidity is low. Some patients might achieve long-term survival.

关键词： synchronous double primary lung cancer surgery prognosis.

Prevalence of Congenital Heart Disease at Extremely High Altitudes in Tibet and the Establishment of a New Free Treatment Model

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Congenital Heart Disease 2022年第6期17卷 709-716页

作者： Shuting Chang Guanzhao zhang Nengjun Sun Xinpeng Yuan Qingting Wang Lin Zhu feiyue zhang Yu Xiu Yang Dong Yonghong Chen Zhanpeng Zhao Xiao Liu Qiang Shao Xiaofeng Xu Anshun Wang Mengjiao Li Bo Li Weifang Medical University WeifangChina Department of Cardiology Shandong University Zibo Central HospitalZiboChina Binzhou Medical University YantaiChina Department of Ultrasound Shandong University Zibo Central HospitalZiboChina Department of Anesthesiology Shandong University Zibo Central HospitalZiboChina Department of Anorectal Surgery Shandong University Zibo Central HospitalZiboChina Department of Obstetrics Shandong University Zibo Central HospitalZiboChina Department of Ultrasonography Qilu Hospital Huantai BranchZiboChina Department of Cardiology Zichuan District HospitalZiboChina Department of Cardiology Zhoucun District HospitalZiboChina Department of Cardiology Zhangdian District HospitalZiboChina Department of Cardiology Boshan District HospitalZiboChina Department of Ultrasound Zibo Municipal HospitalZiboChina Department of Ultrasound Zibo First HospitalZiboChina

Background: This study aimed to illustrate the prevalence of CHD by screening children in extremely high-altitudeareas (over 4000 m to even 5000 m above sea level) and explore an aid model for early diagnosis and treatmentfor the Tibetan population. Methods: A total of 2242 students from different schools in Ngamring County,Xigaze City, Tibet from September 2019 to September 2020 were selected for screening. The students were examinedthrough the inquiry of their current medical history and family history, cardiac auscultation and a physicalexamination, in order to screen out the suspected cases of CHD, and then the suspected cases were confirmed bycardiac color ultrasound examinations. After that, positive patients were be transferred to Shandong Province forfree treatment. Results: The prevalence of CHD among children in Ngamring County was 3.70% (83 cases),which is the highest incidence rate ever reported. The most common type of CHD was patent ductus arteriosus(PDA), accounting for 55.42% of the total number of cases screened, followed by atrial septal defect (ASD) andventricular septal defect (VSD), accounting for 28.92% and 12.05%, respectively. The prevalence of CHD in childrenat high altitude was significantly higher than that in children at low altitude. The children with CHD weretransferred to Shandong Province for surgery, the operations were successful and their recoveries went ***: The results show that high altitude is closely related to the prevalence of CHD, and the incidencein Ngamring County is much higher than that in previous reports.

关键词： Tibet high altitude CHD free treatment model

Cu-Ce/HZSM-5催化剂上的乙醇芳构化反应

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石油学报（石油加工） 2012年第3期28卷 418-425页

作者：张少龙李斌张飞跃黄静李小龙广西大学化学化工学院广西南宁530004

以浸渍法制备了Ce/HZSM-5、Cu/HZSM-5、Cu-Ce/HZSM-5系列催化剂,采用XRD、氮气物理吸附和氨气程序升温脱附方法对其进行了表征,并考察了其催化乙醇芳构化性能。结果表明,Ce和Cu的负载降低了HZSM-5分子筛的比表面积,但分子筛保持原有的... 详细信息

以浸渍法制备了Ce/HZSM-5、Cu/HZSM-5、Cu-Ce/HZSM-5系列催化剂,采用XRD、氮气物理吸附和氨气程序升温脱附方法对其进行了表征,并考察了其催化乙醇芳构化性能。结果表明,Ce和Cu的负载降低了HZSM-5分子筛的比表面积,但分子筛保持原有的骨架结构,且强酸量减少、中强酸量和弱酸量增多;先浸渍Ce再浸渍Cu,Ce和Cu的负载量分别为1.2%和5%的HZSM-5催化剂具有最佳的乙醇芳构化催化性能,在反应温度350℃、质量空速1.0h-1条件下,芳烃收率可达67.6%。

关键词：乙醇芳构化 HZSM-5分子筛

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CAR-T免疫疗法与非小细胞肺癌:瓶颈与曙光

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中国肺癌杂志 2020年第10期23卷 916-920页

作者：张立李恒张飞越王书廷李高峰云南省肿瘤医院胸外科昆明650118

伴随人们对威胁人类健康的非小细胞肺癌(non-small cell lung cancer, NSCLC)更深入的病理生理和发病机制的全新理解,NSCLC治疗已进入一个新时代。从传统以手术、放化疗为基础的治疗过渡到以个体化精准化的靶向治疗和安全性及效能更高... 详细信息

伴随人们对威胁人类健康的非小细胞肺癌(non-small cell lung cancer, NSCLC)更深入的病理生理和发病机制的全新理解,NSCLC治疗已进入一个新时代。从传统以手术、放化疗为基础的治疗过渡到以个体化精准化的靶向治疗和安全性及效能更高的免疫治疗。免疫检查点抑制剂疗法已经被批准为晚期NSCLC一线或者二线的治疗方案,并且取得非同凡响的临床效果。然而,其他类型的免疫治疗在NSCLC中鲜有探索。嵌合抗原受体修饰T细胞(chimeric antigen receptor modified T cells, CAR-T cells)在治疗几种血液系统恶性肿瘤方面表现不俗。然而,其在治疗包括NSCLC在内的实体瘤患者方面却不甚理想。本综述旨在系统阐释CAR-T在NSCLC治疗中的最新进展,主要包括:CAR分子靶标选择、CAR-T功能增强及相关毒性的管理以及CAR-T治疗NSCLC的困境及展望,旨在为NSCLC的免疫治疗开拓新的视角和独特的思路,为肿瘤免疫治疗大厦添砖加瓦。

关键词：肺肿瘤嵌合抗原受体修饰T细胞靶标毒性

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现代服饰:运河非遗手工技艺数字化传承的重要媒介

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纺织报告 2023年第1期42卷 55-57页

作者：张飞越扬州市职业大学艺术学院江苏扬州225009

运河沿岸的非物质文化遗产(以下简称“运河非遗”)既是大运河沿岸人民智慧的结晶,也是中华文明得以延续的重要文化命脉之一。当下,如何运用有效的传播媒介推动运河非遗文化的传播与发展是社会研究的热点。文章提出了以现代服饰作为媒介... 详细信息

运河沿岸的非物质文化遗产(以下简称“运河非遗”)既是大运河沿岸人民智慧的结晶,也是中华文明得以延续的重要文化命脉之一。当下,如何运用有效的传播媒介推动运河非遗文化的传播与发展是社会研究的热点。文章提出了以现代服饰作为媒介能有效传播运河非遗文化的研究命题,在运河非遗和现代服饰相关理论的基础上,从传播学的角度出发,通过界定现代服饰的媒介属性,厘清现代服饰与运河非遗之间的内在关联,分析现代服饰作为运河非遗文化数字化传承传播媒介的传播特征及优势所在。

关键词：运河非遗文化现代服饰传播媒介

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空间机器人预定义任意时间最优轨迹规划

电光与控制 2024年第2期31卷 58-64页

作者：刘宜成张飞越严文四川大学电气工程学院成都610000

针对双臂自由漂浮空间机器人(FFSR)在太空抓取任务中的轨迹规划问题,设计了一种FFSR系统的可实现误差预定义时间收敛的新型轨迹规划算法,用布谷鸟搜索算法进行参数优化,以实现末端执行器误差的快速收敛并获得平滑轨迹。首先,导出FFSR的... 详细信息

针对双臂自由漂浮空间机器人(FFSR)在太空抓取任务中的轨迹规划问题,设计了一种FFSR系统的可实现误差预定义时间收敛的新型轨迹规划算法,用布谷鸟搜索算法进行参数优化,以实现末端执行器误差的快速收敛并获得平滑轨迹。首先,导出FFSR的基于姿态误差的运动学模型;然后,将累积危险场避碰算法应用于预定义任意时间轨迹规划,实现高跟踪精度的快速避碰轨迹;最后,利用布谷鸟搜索算法对预定义任意时间参数进行优化,得到机械臂低关节角速度的运动轨迹。仿真结果表明所提算法能够在预定义的时间内实现末端执行器误差快速收敛,而且能够得到更平滑的运动轨迹。

关键词：空间机器人预定义时间快速避碰布谷鸟搜索算法轨迹规划

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