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Chinese Medical Journal 2024年第12期137卷 1507-1509页

作者： feiyue xiao Pengcheng Li Hang Song Mingchang Zhang Youxin Chen Chan Zhao Department of Ophthalmology Peking Union Medical College HospitalChinese Academy of Medical SciencesBeijing 100005China Key Laboratory of Ocular Fundus Diseases Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100005China Department of Ophthalmology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430030China

To the Editor:Anterior chamber(AC)paracentesis is a commonly performed procedure to lower intraocular pressure(IOP),and to sample aqueous humor(AH)for clinical and research *** suggested by an international collaboration team,an immediately performed AC paracentesis before an intravitreal injection can also prevent post-injection IOP spike.[1]While IOP could immediately be reduced by AC paracentesis,the procedure of obtaining an AH sample(liquid biopsy)is more *** methods have been developed to facilitate AH collection and transfer,[2-7]among which a vacuum-based AH collector(SnovoDAHC I-50,Sightnovo Medical Technology Co.,Beijing,China)has better performance than the commonly used insulin syringe in accurate sampling of about 50μL AH in rabbits by one hand.[7]The current clinical trial aimed to evaluate the performance and safety of this product in human subjects.

关键词： vacuum injection clinical

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前房穿刺采集房水方法的现状

中华眼科杂志 2023年第5期59卷 420-422页

作者：肖菲悦陈有信赵潺中国医学科学院、北京协和医学院、北京协和医院眼科北京100730

前房穿刺采集房水是一项广泛应用于临床的眼科常见技术,对眼内感染、玻璃体视网膜淋巴瘤等疾病的诊断具有重要价值。目前临床上常用的前房穿刺采集房水的方法存在着一些问题和隐患,其操作流程、环境及围术期处理等也尚无统一规范。本文... 详细信息

前房穿刺采集房水是一项广泛应用于临床的眼科常见技术,对眼内感染、玻璃体视网膜淋巴瘤等疾病的诊断具有重要价值。目前临床上常用的前房穿刺采集房水的方法存在着一些问题和隐患,其操作流程、环境及围术期处理等也尚无统一规范。本文将系统回顾前房穿刺采集房水的各种方法和装置,并简要对当前临床前房穿刺的操作环境、围手术期处理及安全性作一综述。

关键词：前房眼房水穿刺抽液术围手术期护理

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无张力疝修补术在腹股沟疝治疗中的效果观察

中国现代医生 2012年第2期50卷 135-136页

作者：肖飞跃陕西省延长县人民医院陕西延长717100

目的探讨无张力疝修补术治疗腹股沟疝的临床效果。方法将我院收治的60例腹股沟疝患者随机分为对照组和观察组:对照组采用传统疝修补术治疗,观察组采用无张力疝修补术治疗;比较两组治疗效果及不良反应发生情况。结果观察组手术时间、术... 详细信息

目的探讨无张力疝修补术治疗腹股沟疝的临床效果。方法将我院收治的60例腹股沟疝患者随机分为对照组和观察组:对照组采用传统疝修补术治疗,观察组采用无张力疝修补术治疗;比较两组治疗效果及不良反应发生情况。结果观察组手术时间、术后恢复时间明显短于对照组,差异有统计学意义(P0.05)。结论无张力疝修补术与传统疝修补术相比,手术时间短,术后患者恢复快,操作方便简单,无明显不良反应发生,值得临床推广应用。

关键词：无张力疝修补术腹股沟疝治疗

Construction of dual heterogeneous interface between zigzag-like Mo–MXene nanofibers and small CoNi@NC nanoparticles for electromagnetic wave absorption

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先进陶瓷(英文) 2023年第8期12卷 1562-1576页

作者： xiaojun Zeng xiao Jiang Ya Ning feiyue Hu Bingbing Fan School of Materials Science and Engineering Jingdezhen Ceramic UniversityJingdezhen 333403China School of Materials Science&Engineering Zhengzhou UniversityZhengzhou 450001China Jiangsu Key Laboratory of Advanced Metallic Materials School of Materials Science and EngineeringSoutheast UniversityNanjing 211189China

Two-dimensional(2D)transition metal carbides(MXene)possess attractive conductivity and abundant surface functional groups,providing immense potential in the field of electromagnetic wave(EMW)***,high conductivity and spontaneous aggregation of MXene suffer from limited EMW *** by dielectric–magnetic synergy effect,the strategy of decorating MXene with magnetic elements is expected to solve this *** this work,zigzag-like Mo_(2)TiC_(2)–MXene nanofibers(Mo-based MXene(Mo–MXene)NFs)with cross-linked networks are fabricated by hydrofluoric acid(HF)etching and potassium hydroxide(KOH)shearing ***,Co-metal–organic framework(MOF)and derived CoNi layered double hydroxide(LDH)ultrathin nanosheets are grown inside Mo–MXene NFs,and the N-doped carbon matrix anchored by CoNi alloy nanoparticles formed by pyrolysis is firmly embedded in the Mo–MXene NFs *** from synergistic effect of highly dispersed small CoNi alloy nanoparticles,a three-dimensional(3D)conductive network assembled by zigzag-like Mo–MXene NFs,numerous N-doped hollow carbon vesicles,and abundant dual heterogeneous interface,the designed Mo–MXene/CoNi–NC heterostructure provides robust EMW absorption ability with a reflection loss(RL)value of−68.45 dB at the thickness(d)of 4.38 *** robust EMW absorption performance can be attributed to excellent dielectric loss,magnetic loss,impedance matching(Z),and multiple scattering and reflection triggered by the unique 3D network *** work puts up great potential in developing advanced MXene-based EMW absorption devices.

关键词： zigzag-like Mo-MXene nanofiber(NF)network dual heterogeneous interface CoNi alloy electromagnetic wave(EMW)absorption

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结合VR仿真技术的教育机器人设计方法研究

太原学院学报（自然科学版） 2024年第4期42卷 14-23页

作者：肖旺群朱飞跃张子文安徽工业大学艺术与设计学院安徽马鞍山243002 安徽皖仪科技股份有限公司研发部安徽合肥230011

为了促进智能机器人的发展,提高智能机器人用户感性意向获取地准确性,弥补教育机器人造型设计中情感化需求的缺失,结合VR仿真技术,提出一种教育机器人造型设计方法。首先,筛选样本并确定用户的感性意向,构建用户的感性意向空间;其次,运... 详细信息

为了促进智能机器人的发展,提高智能机器人用户感性意向获取地准确性,弥补教育机器人造型设计中情感化需求的缺失,结合VR仿真技术,提出一种教育机器人造型设计方法。首先,筛选样本并确定用户的感性意向,构建用户的感性意向空间;其次,运用整体视角下的全局解构法(human interface elements,HIEs)分析设计样本,形成多维设计特征空间;再次,通过VR仿真实验,构建感性意象与设计要素之间的映射关系;最后,根据研究数据进行方案创新设计并完成设计评价,验证方案可行性。研究引入六轴教育机器人为设计实例进行验证,经论证得出,将VR技术引入产品造型设计中的设计流程,可以较为准确地把握用户的感性意向需求,满足设计中用户的情感化需求,推进智能机器人的发展与创新,具有一定的参考价值。

关键词： VR仿真技术教育机器人情感化需求

Linguistic Dynamic Systems Based on Type-2 Fuzzy Sets and Their Stabilities

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Linguistic Dynamic Systems Based on Type-2 Fuzzy Sets and Th...

第二十九届中国控制会议

作者： MO Hong 1,WANG feiyue 2,xiao Zhiquan 3,CHEN Qian 2 1.College of Electric and Information,Changsha University of Science and Technology,Changsha 410004,P.R.China2.The Key Laboratory of Complex System and Intelligence Science,Institute of Automation,Chinese Academy of Science,Beijing 100080,P.R.China3.Institute of Mechanical and Electric,Wuhan College of Science and Technology,Wuhan 430073,P.R.China

In this paper,we first present the interval type-2 fuzzy extension principle and convert the conventional mapping into its type-2 fuzzy ***,we give the procedure of computing with words based on type-2 fuzzy extension... 详细信息

关键词： Type-2 fuzzy sets(T2 FSs),Computing with words(CW),Linguistic dynamic systems(LDS)

来源： cnki会议评论

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鸡粪原料堆肥翻抛机选型及能耗对比

农业工程 2024年第6期14卷 5-10页

作者：郭宪峰李辉肖士军梁浩曹哲统郝鹏鲲王飞跃中机华丰(北京)科技有限公司北京100083

结合多年堆肥工程探索实践经验,详细介绍了链板式翻抛机、轮盘式翻抛机和密闭立式堆肥反应器的工作原理、结构特点、技术参数和适用范围,并以处理鸡粪原料为例,从占地面积、工作效率、单位能耗等方面,对3种堆肥方案进行详细对比分析,以... 详细信息

结合多年堆肥工程探索实践经验,详细介绍了链板式翻抛机、轮盘式翻抛机和密闭立式堆肥反应器的工作原理、结构特点、技术参数和适用范围,并以处理鸡粪原料为例,从占地面积、工作效率、单位能耗等方面,对3种堆肥方案进行详细对比分析,以期为实现鸡粪工厂化快速处理和优化有机肥生产过程提供可靠的技术途径和方法。对比结果表明,轮盘式翻抛机效率较高,维护维修成本低;链板式翻抛机堆肥效果好,主辅料保持混合均匀状态,物料不易分层;密闭立式堆肥反应器自动化程度高,臭气处理压力小。

关键词：鸡粪翻抛机堆肥能耗肥料机械

Study of copper-cysteamine based X-ray induced photodynamic therapy and its effects on cancer cell proliferation and migration in a clinical mimic setting

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Bioactive Materials 2022年第1期7卷 504-514页

作者： Xiangyu Chen Jiayi Liu Ya Li Nil Kanatha Pandey Taili Chen Lingyun Wang Eric Horacio Amador Weijun Chen feiyue Liu Enhua xiao Wei Chen Department of Radiology The Second Xiangya Hospital of Central South UniversityChangshaHunanChina Department of Physics The University of Texas at ArlingtonArlingtonTX76019USA Department of Oncology Xiangya HospitalCentral South UniversityChangshaHunan Province410011China Department of Oncology The Second Xiangya Hospital of Central South UniversityChangshaHunanChina

Copper-cysteamine as a new generation of sensitizers can be activated by light,X-rays,microwaves,or ultrasound to produce reactive oxygen species.X-ray induced photodynamic therapy(X-PDT)has been studied extensively;however,most of the studies reported so far were conducted in the laboratory,which is not conducive to the clinical translation *** this contribution,for the first time,we investigated the treatment efficiency of copper-cysteamine(Cu-Cy)based X-PDT by mimicking the clinical conditions with a clinical linear accelerator and building deep-seated tumor models to study not only the effectiveness but also its effects on the cell migration and proliferation in the level of the cell,tissue,and *** results showed that,without X-ray irradiation,Cu-Cy nanoparticles(NPs)had a low toxicity in HepG2,SK-HEP-1,Li-7,and 4T1 cells at a concentration below 100 mg/***,for the first time,it was observed that Cu-Cy mediated X-PDT can inhibit the proliferation and migration of these cell lines in a dose-dependent *** markers of migration and cell proliferation,proliferating cell nuclear antigen(PCNA)and E-cadherin,from tumor tissue in the X-PDT group were remarkably different from that of the control ***,the MRI assessment showed that the Cu-Cy based X-PDT inhibited the growth of deeply located tumors in mice and rabbits(p<0.05)without any obvious toxicities in ***,these new findings demonstrate that Cu-Cy NPs have a safe and promising clinical application prospect in X-PDT to improve the efficiency of radiotherapy(RT)for deep-seated tumors and effectively inhibit tumor cell proliferation and migration.

关键词： Copper-cysteamine Nanoparticle Photodynamic therapy X-ray Cell migration Proliferation

Garlic-derived compound S-allylmercaptocysteine inhibits hepatocarcinogenesis through targeting LRP6/Wnt pathway

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Acta Pharmaceutica Sinica B 2018年第4期8卷 575-586页

作者： Jia xiao feiyue Xing Yingxia Liu Yi Lv xiaogang Wang Ming-Tat Ling Hao Gao Songying Ouyang Min Yang Jiang Zhu Yu Xia Kwok-Fai So George L.Tipoe State Key Discipline of Infectious Diseases Shenzhen Third People's Hospital Department of Immunobiology Institute of Tissue Transplantation and ImmunologyJinan University School of Biomedical Sciences The University of Hong Kong Department of Cell Biology & Institute of Biomedicine Jinan University Australian Prostate Cancer Research Centre-Queensland and Institute of Health and Biomedical Innovation Queensland University of Technology Institute of Traditional Chinese Medicine and Natural Products College of PharmacyJinan University Biomedical Research Center of South China College of Life SciencesFujian Normal University JM Medical (Shenzhen) LLC GMH Institute of Central Nervous System Regeneration Jinan University

Whether and how garlic-derived S-allylmercaptocysteine(SAMC) inhibits hepatocellular carcinoma(HCC) is largely unknown. In the current study, the role of low-density lipoprotein receptor(LDLR)-related protein 6(LRP6) in HCC progression and the anti-HCC mechanism of SAMC was examined in clinical sample, cell model and xenograft/orthotopic mouse models. We demonstrated that SAMC inhibited cell proliferation and tumorigenesis, while induced apoptosis of human HCC cells without influencing normal hepatocytes. SAMC directly interacted with Wnt-pathway co-receptor LRP6 on the cell membrane. LRP6 was frequently over-expressed in the tumor tissue of human HCC patients(66.7% of 48 patients) and its overexpression only correlated with the over-expression of β-catenin, but not with age, gender, tumor size, stage and metastasis. Deficiency or over-expression of LRP6 in hepatoma cells could partly mimic or counteract the anti-tumor properties of SAMC, respectively. In vivo administration of SAMC significantly suppressed the growth of Huh-7 xenograft/orthotopic HCC tumor without causing undesirable side effects. In addition, stable down-regulation of LRP6 in Huh-7 facilitated the anti-HCC effects of SAMC. In conclusion, LRP6 can be a potential therapeutic target of HCC. SAMC is a promising specific anti-tumor agent for treating HCC subtypes with Wnt activation at the hepatoma cell surface.

关键词： S-allylmercaptocysteine HCC Wnt LRP6 Human Nude mice

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国家植物园创建下的上海植物园科研体系构建

园林 2024年第S1期41卷 18-25页

作者：李燕肖月娥严巍张健楚秀丽王翠梅徐菲悦张婷陆海燕上海植物园上海200231 上海城市植物资源开发应用工程技术研究中心上海200231

作为国家植物园创建中重要的联合创建单位,上海植物园是国内建设较早的植物园之一,担负着服务城市和满足国家战略需求的重要使命。主要介绍上海植物园在科研平台建设以及迁地保育、特色观赏植物资源种质创新与利用、生物多样性保护与树... 详细信息

作为国家植物园创建中重要的联合创建单位,上海植物园是国内建设较早的植物园之一,担负着服务城市和满足国家战略需求的重要使命。主要介绍上海植物园在科研平台建设以及迁地保育、特色观赏植物资源种质创新与利用、生物多样性保护与树木生态方面取得的科研成果,在此基础上,重点阐述上海植物园积极响应国家植物园体系建设目标,立足华东区域,服务国家战略需求,面向国内领先、国际一流植物园发展要求,打造上海植物园特色科研体系三大版块:华东野生植物保护中心和重要类群全球种质资源库、华东城市特色观赏植物资源创新研究中心、城市生物多样性保护;首次提出“创新工作机制,加强科研管理”“加大资金投入,提升发展环境”“重视人才培养,打造人才高地”“推动成果转化,加大科研宣传”“深入合作交流,促进高速发展”的“四位一机制”保障措施,落实上海植物园发展战略,融入国家植物园建设新格局。

关键词：科研体系上海植物园国家植物园