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Heparin is an effective treatment for preventing liver failure after hepatectomy

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World Journal of Gastroenterology 2024年第22期30卷 2881-2892页

作者： Zhi-Ying Xu Min Peng Ming-Ming Fan Qi-fei zou Yi-Ran Li Dong Jiang Hepatic Surgery IV Shanghai Eastern Hepatobiliary Surgery HospitalThe Third Affiliated Hospital of Naval Medical UniversityShanghai 200433China Ultrasound Diagnosis PLA Naval Medical CenterShanghai 200437China Department of Ultrasound Eastern Hepatobiliary Surgery HospitalThe Third Affiliated Hospital of Naval Medical UniversityShanghai 200433China

BACKGROUND Posthepatectomy liver failure(PHLF)is one of the most important causes of death following liver ***,an established anticoagulant,can protect liver function through a number of mechanisms,and thus,prevent liver *** To look at the safety and efficacy of heparin in preventing hepatic dysfunction after *** The data was extracted from Multiparameter Intelligent Monitoring in Intensive Care III(MIMIC-III)v1.4 pinpointed patients who had undergone hepatectomy for liver cancer,subdividing them into two cohorts:Those who were injected with heparin and those who were *** statistical evaluations used were unpaired ttests,Mann-Whitney U tests,chi-square tests,and Fisher’s exact tests to assess the effect of heparin administration on PHLF,duration of intensive care unit(ICU)stay,need for mechanical ventilation,use of continuous renal replacement therapy(CRRT),incidence of hypoxemia,development of acute kidney injury,and ICU *** regression was utilized to analyze the factors related to PHLF,with propensity score matching(PSM)aiming to balance the preoperative disparities between the two *** In this study,1388 patients who underwent liver cancer hepatectomy were *** yielded 213 matched pairs from the heparin-treated and control *** univariate analyses indicated that heparin potentially reduces the risk of PHLF in both matched and unmatched *** analysis in the matched cohorts confirmed a significant association,with heparin reducing the risk of PHLF(odds ratio:0.518;95%confidence interval:0.295-0.910;P=0.022).Additionally,heparin treatment correlated with improved short-term postoperative outcomes such as reduced ICU stay durations,diminished requirements for respiratory support and CRRT,and lower incidences of hypoxemia and ICU *** Liver failure is an important hazard following hepatic *** ICU care heparin administration has been proved to decr

关键词： Liver resection Posthepatectomy liver failure Prophylactic treatment Heparin Prognosis of hepatectomy

定向凝固条件下Ti_(3)Al合金中梯度纳米结构的形成机制与力学行为——原子尺度研究

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Transactions of Nonferrous Metals Society of China 2024年第5期34卷 1507-1519页

作者：邹鹏飞李昌侯兆阳 Jia-yi SUN 高全华李克凡王真 Ke-jun DONG 长安大学理学院西安710064 Faculty of Natural Mathematics&Engineering SciencesKing’s College LondonLondonWC2R 2LSUnited Kingdom School of Engineering Design and Built EnvironmentWestern Sydney UniversityPenrithNSW 2751Australia

通过分子动力学(MD)模拟方法对Ti_(3)Al合金在定向凝固条件下的生长机理进行系统研究,并通过对比纳米晶(NG)、粗晶(CG)和梯度纳米晶(GNG)合金,研究Ti_(3)Al合金的结构力学性能。结果表明,在凝固过程中Ti_(3)Al相优先生长为等轴晶组织,... 详细信息

通过分子动力学(MD)模拟方法对Ti_(3)Al合金在定向凝固条件下的生长机理进行系统研究,并通过对比纳米晶(NG)、粗晶(CG)和梯度纳米晶(GNG)合金,研究Ti_(3)Al合金的结构力学性能。结果表明,在凝固过程中Ti_(3)Al相优先生长为等轴晶组织,随后逐渐演变为柱状粒,并最终形成梯度纳米晶结构。此时,晶粒在与凝固方向平行的方向优先生长。此外,研究还发现,相较于NG和CG结构,GNG结构定向凝固合金具有更高的抗拉强度和更好的延展性。GNG结构不仅有效抑制了小晶粒区域的应变局域化和晶粒生长,而且促进了较大晶粒区域的位错形成,从而获得更好的力学性能。

关键词：定向凝固 Ti_(3)Al合金分子动力学模拟梯度纳米结构

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窖泥微生物多样性及窖泥评价与养护研究进展

食品科学 2024年第16期45卷 320-328页

作者：邹斐叶力冯亮郑晓卫黄彪夏冰张无疾陈晓园方正国孙玉婷酒鬼酒股份有限公司湖南吉首416000 中粮营养健康研究院有限公司北京102209

全泥窖池固态发酵是浓香型与馥郁香型白酒的典型酿造工艺。窖泥作为窖池的功能载体,其微生物的丰度、多样性、代谢活性及相互间的作用关系直接影响白酒质量。本文从传统培养技术与非培养技术下的窖泥微生物研究方法、基于空间与时间维... 详细信息

全泥窖池固态发酵是浓香型与馥郁香型白酒的典型酿造工艺。窖泥作为窖池的功能载体,其微生物的丰度、多样性、代谢活性及相互间的作用关系直接影响白酒质量。本文从传统培养技术与非培养技术下的窖泥微生物研究方法、基于空间与时间维度下的窖泥微生物群落结构差异、窖泥功能菌株及其相互作用、窖泥质量评价方法构建与完善,以及以功能菌株为核心的窖泥养护与老熟等方面进行综述,总结不同技术方法在白酒微生物研究领域的发展沿革与应用现状,窖泥老熟过程中原核与真核微生物消长变化规律及窖池不同空间位置下原核与真核微生物分布的差异情况,己酸菌、丁酸菌、乳酸菌、醋酸菌和甲烷菌等窖泥核心功能微生物的作用与相互依存关系,窖泥老化原因,窖泥质量评价标准从传统感官和理化分析等单一维度向综合评判体系方法和评价机制构建与应用的转变,以及基于核心菌株的功能化属性所开展的养护与老熟研究,旨在为后续学者针对窖泥微生物多样性评估、菌群代谢功能研究及窖泥养护改良工艺研究等提供参考。

关键词：白酒窖泥微生物多样性功能菌株养护评价

“桥”式保留中鼻甲EESS在EOS型慢性鼻窦炎伴鼻息肉中的疗效观察

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中国医学创新 2024年第13期21卷 11-14页

作者：杨明鲍希安朱皓华邹飞邹文苗春雨南昌市第一医院耳鼻喉科江西南昌330008

目的:探究“桥”式保留中鼻甲扩展式内镜鼻窦手术(extended endoscopic sinus surgery,EESS)在嗜酸性粒细胞(eosinophil,EOS)型慢性鼻窦炎伴鼻息肉(chronic rhinosinusitis with nasal polyps,CRSwNP)中的临床效果。方法:选取2021年7月—2023年5月于南昌市第一医院就诊的EOS型CRSwNP患者60例,随机分为对照组和观察组,各30例。对照组采用功能性内镜鼻窦手术(functional endoscopic sinus surgery,FESS)治疗,观察组采用“桥”式保留中鼻甲EESS治疗。观察两组临床疗效、鼻腔功能及嗅觉功能、术中出血量及术后并发症发生情况。结果:观察组术中出血量明显少于对照组,临床总有效率明显高于对照组(P<0.05);观察组术后鼻腔容积、鼻腔最小横截面积均明显大于对照组,鼻气道阻力、嗅觉功能评分及并发症发生率明显均低于对照组(P<0.05)。结论:“桥”式保留中鼻甲EESS应用于EOS型CRSwNP中的临床效果显著,可明显减少术中出血量,改善患者的鼻腔功能及嗅觉功能,并降低术后并发症发生率。

关键词：慢性鼻窦炎鼻息肉鼻窦手术嗅觉功能

Time-Coordinated Path Following for Multiple Agile Fixed-Wing UAVs with End-Roll Expectations

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Guidance, Navigation and Control 2023年第4期3卷 58-84页

作者： fei zou Jie Li Yifeng Niu College of Intelligence Science and Technology National University of Defense Technology Changsha 410078 P.R.China

This paper presents a control strategy for multiple unmanned aerial vehicle systems(multi-UAVs)time-coordinated path following with desired endpoint roll *** utilizes the strong maneuvering capabilities of agile fixed-wing UAVs and incorporates an end-roll *** strategy consists of four steps:time-coordinated control,position control,roll angle planning and attitude *** position and attitude controllers exhibit Lyapunov exponential *** time-coordinated controller addresses the synchronization problem by adjusting the speed based on the coordinated state to achieve progress *** position controller operates based on the cross-track error and altitude error in the Gravity-Referenced Moving *** employing an optimization approach and designing a penalty function,the roll angle sequence is *** attitude inner-loop control operates in the SO(3)space and allows for control of large ***-fidelity simulation validates the effectiveness of the proposed method,with normalized coordination error and following error controlled within 2%and 1.2m.

关键词： Agile fixed-wing time-coordinated control path following roll angle planning

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花生壳基硬碳孔结构调控及储钠性能研究

现代化工 2024年第8期44卷 110-114,120页

作者：左宇程吉闫张京涛邹飞杨葛志清陈召勇长沙理工大学材料科学与工程学院湖南长沙410114

以花生壳为原料,采用固相熔融扩散碳化法调控花生壳基衍生硬碳的孔结构制得改性的花生壳衍生硬碳负极材料;通过扫描电镜(SEM)、X射线衍射(XRD)、全自动比表面及孔隙度分析仪对其进行表征分析,并对组装的钠离子半电池进行恒电流电化学充... 详细信息

以花生壳为原料,采用固相熔融扩散碳化法调控花生壳基衍生硬碳的孔结构制得改性的花生壳衍生硬碳负极材料;通过扫描电镜(SEM)、X射线衍射(XRD)、全自动比表面及孔隙度分析仪对其进行表征分析,并对组装的钠离子半电池进行恒电流电化学充放电测试、循环伏安测试(CV)以及电化学阻抗测试。结果表明,在30 mA/g的电流密度下,材料的可逆容量达到350 mAh/g,在300 mA/g的电流密度下仍能稳定保持335 mAh/g的可逆容量,并且能在高倍率充放电下具有优异的倍率性能。

关键词：硬碳钠离子电池负极材料电化学性能孔结构

2-Pyridinylmethyl borrowing:base-promoted C-alkylation of(pyridin-2-yl)-methyl alcohols with ketones via cleavage of unstrained C(sp^(3))-C(sp^(3))bonds

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Organic Chemistry Frontiers 2022年第2期9卷 299-304页

作者： Chuan-Ming Hong fei-fei zou Xin Zhuang Zhen Luo Zheng-Qiang Liu Li-Qing Ren Qing-Hua Li Tang-Lin Liu School of Chemistry and Chemical Engineering Southwest UniversityChongqing 400715China

A transition metal-free synthesis of β-(pyridin-2-yl)-methyl ketones,using(pyridin-2-yl)methyl alcohols and ketones through the 2-pyridinylmethyl borrowing strategy,has been *** approach provides an efficient,available and environmentally benign access,leading to alkylation products with broad functional group tolerance and excellent ***,the selective cleavage of unactivated C(sp^(3))-C(sp^(3))bonds of common secondary alcohols was achieved with high atom economy.

关键词： alcohols bonds cleavage

Does City Shape Affect China's Economic Development?

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China & World Economy 2024年第1期32卷 21-56页

作者： Wei zou fei Yang Economics and Management School Wuhan UniversityChina

This paper constructs a general equilibrium spatial urban model and measures city geometric compactness using the patch-shape index based on evidence from satellite imagery and basic vector maps of *** adopts the ordinary least squares and instrumental variable approaches to examine the effect of city shape on the urban development of 279 Chinese cities at or above the prefecture *** empirical results show that there was a significant negative correlation between city shape and economic ***,every 1 percentage point increase in the patch-shape index led to a decrease in city-scale GDP by 0.009 percent,housing prices by 0.044 percent,and wages by 0.024 *** compact urban layouts attracted an inflow of households and firms,stimulated city economic growth,and were associated with increased housing prices and wage *** paper considers the cities'initial conditions,trends in population changes(expanding,shrinking,and stagnant cities),and geographic factors,and finds that the results are *** array of policy implications can be drawn from the research.

关键词： city footprint compactness economic development urban spatial shape

Numerical manifold method for thermo-mechanical coupling simulation of fractured rock mass

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第6期16卷 1977-1992页

作者： Jiawei Liang Defu Tong fei Tan Xiongwei Yi Junpeng zou Jiahe Lv Faculty of Engineering China University of GeosciencesWuhan430074China Department of Civil Engineering Monash UniversityClaytonVIC3800Australia Badong National Observation and Research Station of Geohazards China University of GeoscienceWuhan430074China

As a calculation method based on the Galerkin variation,the numerical manifold method(NMM)adopts a double covering system,which can easily deal with discontinuous deformation problems and has a high calculation *** at the thermo-mechanical(TM)coupling problem of fractured rock masses,this study uses the NMM to simulate the processes of crack initiation and propagation in a rock mass under the influence of temperature field,deduces related system equations,and proposes a penalty function method to deal with boundary *** examples are employed to confirm the effectiveness and high accuracy of this *** the thermal stress analysis of a thick-walled cylinder(TWC),the simulation of cracking in the TWC under heating and cooling conditions,and the simulation of thermal cracking of the SwedishÄspöPillar Stability Experiment(APSE)rock column,the thermal stress,and TM coupling are *** numerical simulation results are in good agreement with the test data and other numerical results,thus verifying the effectiveness of the NMM in dealing with thermal stress and crack propagation problems of fractured rock masses.

关键词： Heat conduction Fractured rock mass Crack propagation Galerkin variation Numerical manifold method(NMM)