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Global research landscape of Peutz-Jeghers syndrome and successful endoscopic management of intestinal intussusception in patients with recurrent laparotomies

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2702-2718页

作者： Qi Sun Xiao-Ying Wang Guang-Jin guo Lei Wang Li-Min Meng Yun-fei guo Tao Sun Shou-Bin Ning Department of Gastroenterology Air Force Medical CenterBeijing 100142China College of Life Science Northwest UniversityXi'an 710069Shaanxi ProvinceChina Clinical Medical Laboratory Air Force Medical CenterBeijing 100142China Department of Medical Imaging Air Force Medical CenterBeijing 100142China Department of Pathology Air Force Medical CenterBeijing 100142China

BACKGROUND Peutz-Jeghers syndrome(PJS)has brought significant physical,psychological and economic burdens on the patients and their families due to its early onset,diagnostic and therapeutic challenges and increased recurrence *** To explore the current research status and emerging hotspots of *** Studies on PJS published during 1994-2023 were gathered based on Web of Science Core ***,a case of PJS-induced intestinal intussusception,successfully treated with endoscopic methods despite three laparotomies,was *** bibliometric and visual analysis were conducted with VOSviewer,R and *** Altogether 1760 studies were identified,indicating a steady increase in the publication *** United States had the highest influence,whereas the University of Helsinki emerged as the leading institution,and Aaltonen LA from the University of Helsinki was the most prolific *** Research,Oncogene and Endoscopy were the top three journals based on *** burst direction analysis revealed that"cancer risk","management","surveillance"and"familial pancreatic cancer"were the potential hotspots for ***,"early detection","capsule endoscopy","clinical management","double-balloon endoscopy","familial pancreatic cancer"and"molecular genetic basis"were identified as the key clusters of co-cited *** polypectomy remained effective on resolving intestinal intussusception in patients who underwent three previous *** In the last three decades,global publications related to PJS show a steadily increasing trend in *** management is currently a research hotspot.

关键词： Peutz-Jeghers syndrome Endoscopy Management Cancer Microbiota Bibliometric

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Identification of an H1N1 subtype of swine influenza virus and serological analysis

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Journal of Integrative Agriculture 2019年第7期18卷 1436-1442页

作者： SUN Fa-chao TAN Min ZHANG Yuan-chao WANG Yu-chao CAO Sheng-liang DING guo-fei CONG Fang-yuan guo Li-hong LIU Si-dang XIAO Yi-hong Department of Basic Veterinary Medicine College of Animal Science and Veterinary Medicine/Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention/Shandong Provincial Engineering Technology Research Center of Animal Disease Control and PreventionShandong Agricultural University

To investigate the epizootic of swine influenza virus(SIV),60 nasal swabs were collected from a clinical cases of pig farm in Tai’an City,Shandong Province of China in April *** was isolated by inoculating into 10-day-old Special Pathogen Free embryonated eggs and the whole genome was *** H1N1 subtype SIV was isolated and designated as A/swine/Shandong/TA04/2017(H1N1).Phylogenetic analysis showed that apart from the polymerase A(PA) fragment belonging to the 2009 pandemic H1N1 branch,seven genome segments belonged to avian-like H1N1 influenza virus *** cleavage site sequence of the hemagglutinin(HA) protein was PSIQSR↓G,which is a typical molecular biological *** potential N-glycosylation sites(N14,N26,N277,N484 and N543) were found in the HA *** further investigate the epidemiology of SIV in this farm,the 995 serum samples were assessed with EAH1N1 2009 pandemic H1N1 and H3 N2 *** results showed that the total positive rate was 65.43%.The positive rates of single virus infection detected by EAH1N1,2009 pdmH1N1 and H3 N2 for serum HI(Hemagglutination inhibition) were 48.35,30.85 and 7.47%,*** results showed that SIV in Shandong Province has been reassorted in some segments and the SIV-positive rate was high on the SIV outbreak *** data provide evidence of an epizootic of SIV.

关键词： SIV H1N1 subtype genetic analysis molecular feature serology

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Effects and mechanism of igneous rock on selenium in the tropical soil-rice system in Hainan Province, South China

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China Geology 2022年第1期5卷 1-11页

作者： Xiu-jin Liu Ke Yang fei guo Shi-qi Tang Ying-han Liu Li Zhang Hang-xin Cheng fei Liu Institute of Geophysical and Geochemical Exploration Chinese Academy of Geological SciencesLangfang 065000China Key Laboratory of Geochemical Cycling of Carbon and Mercury in the Earth’s Critical Zone Chinese Academy of Geological SciencesLangfang 065000China Research Center of Geochemical Survey and Assessment on Land Quality China Geological SurveyLangfang 065000China

To illuminate the migration and transformation of selenium(Se)in the igneous rock-soil-rice system,285 pairs of rhizosphere soil and rice samples were collected from the granitoid and basalt areas in Hainan Province,South *** contents of Se in soils derived from granitoid and basalt are,respectively,0.19±0.12 mg/kg and 0.34±0.39 mg/kg,which are much higher than Se contents in granitoid and *** shows remarkable enrichment from granitoid and basalt to *** mobile fraction of Se in soils derived from granitoid is 0.0100±0.0034 mg/kg,which is significantly higher than that of basalt(0.0058±0.0039 mg/kg).Although soil derived from basalt shows higher Se contents,Se contents in rice samples,mobile fractions of Se in soils,and biological concentration factor(BCF)is similar or even lower than that from *** consist of calcic plagioclase and pyroxene,and are much richer in Fe,Al,and Ca than ***,the basalt-derived soils have higher goethite,hematite,kaolinite,cation exchange capacity(CEC)content,and higher p H than the granitoid-derived soils,which result in higher adsorption capacity for Se and relatively lower Se *** derived from granitoid and basalt in tropical regions are beneficial to produce Se-rich rice.

关键词： Selenium Granitoid Basalt Soil properties Tropical soil Se-rich rice Agricutural geological survey engineering Hainan Province China

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A stretchable and adhesive ionic conductor based on polyacrylic acid and deep eutectic solvents

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npj Flexible Electronics 2021年第1期5卷 175-182页

作者： Gang Li Zhihao Deng Minkun Cai Kaixi Huang Mengxue guo Ping Zhang Xingyu Hou Yuan Zhang Yueji Wang Yan Wang Xiang Wu Chuan fei guo Department of Materials Science and Engineering Southern University of Science and TechnologyShenzhenChina Department of Mechanics and Aerospace Engineering Southern University of Science and TechnologyShenzhenChina School of Materials Science and Engineering Shenyang University of TechnologyShenyangLiaoningChina Guangdong Provincial Key Laboratory of Functional Oxide Materials and Devices Southern University of Science and TechnologyShenzhenGuangdongChina

Hydrogels are a widely used ionic conductor in on-skin electronic and iontronic ***,hydrogels dehydrate in the open air and freeze at low temperatures,limiting their real applications when they are attached on skin or exposed to low ***-ionic liquid gels can overcome these two obstacles,but synthetic ionic liquids are expensive and *** this work,we present an ionic conductor based on polyacrylic acid(PAAc)and deep eutectic solvents(DESs)that well addresses the aforementioned *** polymerize acrylic acid in DESs to get the PAAc–DES gel,which exhibits excellent stretchability(>1000%),high electrical conductivity(1.26 mS cm^(−1)),high adhesion to the skin(~100 Nm^(−1)),as well as good anti-drying and anti-freezing *** also demonstrate that the PAAc-DES gel can be used as an on-skin electrode to record the surface electromyographic signal with high signal quality,or as a transparent stretchable electrode in iontronic devices that can work at–20℃.We believe that the PAAc–DES gels are an ideal candidate as epidermal electrodes or transparent stretchable electrodes.

关键词： properties ionic conductor

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Clinical application of vascular occlusion test based on tissue oxygen saturation monitoring

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Journal of Hainan Medical University 2020年第2期26卷 67-71页

作者： fei guo Lei Du Department of Anesthesia West China HospitalSichuan UniversityChengdu610041P.R.China Department of Anesthesia Zigong Fourth People's HospitalSichuan643000P.R.China

The vascular occlusion test (VOT) is an experiment that simulates the process of distal ischemia-reperfusion of tissue based on the monitoring of tissue oxygen saturation (StO2) to obtain VOT parameters related to StO2 changes to evaluate microcirculation function of the measured muscle tissue. VOT has the advantages of real-time, noninvasive and continuous, and is widely used to evaluate the functional status of peripheral microcirculation and the relationship between microcirculation changes and prognosis of patients. In clinical work, doctors mainly focus on hemodynamics of patients, while microcirculation function is often neglected due to the lack of real-time monitoring methods, which may lead to severe poor prognosis of patients, especially patients with critical illness. This paper focuses on the clinical application of vascular occlusion test based on tissue oxygen saturation monitoring.

关键词： Vascular occlusion test Regional oxygen saturation Microcirculation dysfunction Clinical application

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A novel onlay urethroplasty for hypospadias with mild chordee after degloving:modified for complete removal of scar tissue underlying the urethral plate and for long-term outcomes

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Asian Journal of Andrology 2022年第6期24卷 639-642页

作者： Li-Qu Huang Zheng Ge Li-Xia Wang Xiao-Yu Li Yong-Ji Deng Yun-fei guo Geng Ma Department of Urology Children's Hospital of Nanjing Medical UniversityJiangsu Provincial Children's Medical CenterNanjing 210008China

Urethral plate(UP)-preserving urethroplasty is simple and has few complications,but it may affect the development of penis in the long term and lead to recurrent *** this study,we used obliquely cut UP to repair hypospadias with mild chordee after degloving(15°-30°)and compared the results with onlay urethroplasty to explore its rationality and *** April 2018 and October 2020,108 hypospadias patients underwent onlay urethroplasty or modified onlay *** data were prospectively collected,and medium-term outcomes were assessed at *** complications were compared between the two ***-four patients underwent the modified onlay procedure(GroupⅠ),with follow-up time(mean±standard deviation[s.d.])of 23.2±4.5(range:17-31)***-four patients underwent a standard onlay procedure(GroupⅡ),with follow-up time(mean±s.d.)of 39.7±3.9(range:32-46)*** was no difference in age at *** urethral defect length and operative time were longer in GroupⅠ.Six cases of fistula and one case each of stricture and diverticulum were reported in GroupⅠ.In GroupⅡ,11 cases of fistula and one case each of stricture and diverticulum were *** complication rates were 18.2%and 20.3%in GroupⅠand GroupⅡ,respectively(P>0.05).These medium-term follow-up results demonstrate that the modified onlay procedure(oblique cut UP urethroplasty)is a safe and feasible technique for hypospadias with mild chordee after *** with standard onlay urethroplasty,this modified procedure is conducive to the complete removal of scar tissue underlying the UP without increasing the risk of surgical complications.

关键词： complications hypospadias penile curvature urethral plate

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Heterostructural NiFeW disulfide and hydroxide dual‐trimetallic core‐shell nanosheets for synergistically effective water oxidatio

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Carbon Energy 2024年第8期6卷 192-204页

作者： Peng‐fei guo Yang Yang Bing Zhu Qian‐Nan Yang Yan Jia Wei‐Tao Wang Zhao‐Tie Liu Shi‐Qiang Zhao Xun Cui Key Laboratory of Chemical Additives for China National Light Industry College of Chemistry and Chemical EngineeringShaanxi University of Science and TechnologyXi'anChina School of Chemistry and Chemical Engineering Shaanxi Normal UniversityXi'anChina Key Laboratory of Carbon Materials of Zhejiang Province Wenzhou Key Lab of Advanced Energy Storage and ConversionZhejiang Province Key Lab of Leather EngineeringCollege of Chemistry and Materials EngineeringWenzhou UniversityWenzhouChina State Key Laboratory of New Textile Materials and Advanced Processing Technologies Wuhan Textile UniversityWuhanChina

A stable and highly active core‐shell heterostructure electrocatalyst is essential for catalyzing oxygen evolution reaction(OER).Here,a dual‐trimetallic core‐shell heterostructure OER electrocatalyst that consists of a NiFeWS_(2) inner core and an amorphous NiFeW(OH)_(z)outer shell is designed and synthesized using in situ electrochemical *** electrochemical measurements of different as‐synthesized catalysts with a similar mass loading suggest that the core‐shell Ni_(0.66)Fe_(0.17)W_(0.17)S_(2)@amorphous NiFeW(OH)_(z) nanosheets exhibit the highest overall performance compared with that of other bimetallic reference catalysts for the ***,the nanosheet arrays were in situ grown on hydrophilic‐treated carbon paper to fabricate an integrated three‐dimensional electrode that affords a current density of 10 mA cm^(−2) at a small overpotential of 182 mV and a low Tafel slope of 35 mV decade^(−1) in basic *** Faradaic efficiency of core‐shell Ni_(0.66)Fe_(0.17)W_(0.17)S_(2)@amorphous NiFeW(OH)_(z) is as high as 99.5% for *** scanning electron microscope,transmission electron microscope,and X‐ray photoelectron spectroscopy analyses confirm that this electrode has excellent stability in morphology and elementary composition after long‐term electrochemical ***,density functional theory calculations further indicate that the core‐shell heterojunction increased the conductivity of the catalyst,optimized the adsorption energy of the OER intermediates,and improved the OER *** study provides a universal strategy for designing more active core‐shell structure electrocatalysts based on the rule of coordinated regulation between electronic transport and active sites.

关键词： amorphous NiFeW hydroxide core‐shell heterojunction in situ electrochemical tuning NiFeW disulfide oxygen evolution reaction

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Multiple pulmonary ground-glass nodules: Challenges and advances

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Journal of Nutritional Oncology 2023年第2期8卷 85-93页

作者： fei-fei guo Jue Huang fei Chen Jiu-Wei Cui Cancer Center The First Hospital of Jilin UniversityChangchunChina

Multiple pulmonary ground-glass nodules(GGNs),a typical clinical manifestation of multiple primary lung cancers(MPLCs),are of great significance for the early screening,diagnosis,and accurate treatment of lung ***,the recent increase in the detection rate of multiple pulmonary GGNs has attracted much ***,compared with the more widely studied single GGNs,evaluating GGNs is more challenging because of the uncertainty of the etiology,difficult differential diagnosis,and lack of optimal management standards and *** current solutions for multiple GGNs are based on the management experiences and principles of a single ***,it is necessary to obtain better understanding of multiple GGNs and to optimize the diagnostic methods and *** the existing challenges and potential of new methods for diagnosing and treating multiple pulmonary GGNs are reviewed and discussed in this article,with the aim of providing a reference for the clinical management of this highly prevalent condition.

关键词： Multiple pulmonary GGNs MPLC Treatment of lung cancer Guidelines

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Effect of thermophysical property and coating thickness on microstructure and characteristics of a casting

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China Foundry 2017年第1期14卷 46-54页

作者： Ai-chao Cheng Bo-lin Jia Ren-fei guo Xiu-ping Ren Hui-bin Xuan Tie-tao Zhou School of Materials Science and Engineering Beihang UniversityBeijing 100191China Yuneheng Guanlv Equipment Material Co. LtdShanxi 444501China State Key Laboratory of Nonlinear Mechanics Institute of MechanicsChinese Academy of SciencesBeijing 100190China

A new improved investment casting technology （IC） has been presented and compared with the existing IC technology such as lost foam casting （LFC）. The effect of thermophysical property and coating thickness on casting solidification temperature field, microstructure and hardness has been investigated. The results show that the solidification rate decreases inversely with the coating thickness when the coating contains silica sol, zircon powder, mullite powder and defoaming agent. In contrast, the solid cooling rate increases as the coating thickness increases. However, the solidification rate and solid cooling rate of the casting produced by the existing IC and the improved IC are very similar when the coating thickness is 5 mm, so the microstructure and hardness of a container corner fitting produced by the improved IC and the existing IC are similar. The linear regression equation for the grain size （d） and cooling rate （v） of the castings is d= -0.41v＋206.1. The linear regression equation for the content of pearlite （w） and solid cooling rate （t） is w=1.79t ＋ 6.71. The new improved IC can greatly simplify the process and decrease the cost of production compared with the existing IC. Contrasting with LI=C, container corner fittings produced by the new improved IC have fewer defects and better properties. It was also found that the desired microstructure and properties can be obtained by changing the thermophysical property and thickness of the coating.

关键词： improved investment casting thermophysical property coating thickness microstructure property

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梦的奇幻与真实

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科学通报 2018年第1期63卷 22-31页

作者：郭菲陈祉妍中国科学院心理健康重点实验室(中国科学院心理研究所) 北京100101

梦是人们最为普遍的经验之一,由于其栩栩如生和离奇的特点,人类很早就对这种现象充满了好奇.为什么会做梦这个谜题在科学技术不断发展的同时也得到了更为广泛的研究.作为一种古老的生理心理现象,梦是否具有适应性的功能引发了丰富的理... 详细信息

梦是人们最为普遍的经验之一,由于其栩栩如生和离奇的特点,人类很早就对这种现象充满了好奇.为什么会做梦这个谜题在科学技术不断发展的同时也得到了更为广泛的研究.作为一种古老的生理心理现象,梦是否具有适应性的功能引发了丰富的理论思考,而对于其功能性在于做梦这种形式还是梦境的内容还需要更多的研究予以解答.对于梦的科学研究已从聚焦于非快速眼动睡眠扩展到了整个睡眠阶段.而梦作为一种特殊的意识状态,其与清醒状态在现象学和大脑活动上的异同,将为了解人类意识提供重要的信息,特别是清醒梦这种兼具清醒和睡眠特点的状态,为揭示意识的神经机制提供了独特的机会.此外梦的研究对于临床心理和精神问题也有实践意义.梦的研究面临着很多方法上的挑战,解开梦的奥秘需要整合现象学、神经科学、临床研究等多个领域的设计和方法.

关键词：梦做梦睡眠意识神经科学

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