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麻醉与监护论坛 2014年第1期21卷 67-68页

作者： wen-fei Tan Hong Ma Department of Anesthesiology the First Hospital of China Medical University

Deuterium NMR Studies on the Orientational Order Generated in Strained Rubbers

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Chemical Research in Chinese Universities 1992年第2期8卷 110-113页

作者： LI fei, YANG Dai-wen, GAO Ping and QIU Zu-wen (Institute of Theoretical Chemistry, Jilin University, Changchun, 130023)

The present paper deals with the induced orientational order of the probe molecules dissolved in the uniaxially strained rubbers measured by using deuterium NMR. The distinctive dependence of the quadrupolar splitting on the swelling, elongation and crosslinking density was observed. The orientational order arising from the correlation between chain segments decreases with the increase of the numbers of both links between junctions and solvent molecules around segments.

关键词： Orientational order Rubbers Deuterium NMR Crosslinking density,Segment-segment correlation

辽东半岛辽河群变泥质岩变质变形研究:对古元古代造山作用及折返过程的启示

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岩石学报 2021年第2期37卷 619-635页

作者：文飞田忠华中国地质科学院地质研究所北京100037

前寒武纪造山带解析是地球科学研究的重点。胶-辽-吉造山带作为华北克拉通最具代表性的造山带之一,是研究前寒武纪造山过程和物质折返的理想场所。本文以辽东半岛辽河群为研究对象,以变质变形为研究手段,系统解析胶-辽-吉造山带的造山... 详细信息

前寒武纪造山带解析是地球科学研究的重点。胶-辽-吉造山带作为华北克拉通最具代表性的造山带之一,是研究前寒武纪造山过程和物质折返的理想场所。本文以辽东半岛辽河群为研究对象,以变质变形为研究手段,系统解析胶-辽-吉造山带的造山及折返过程。含夕线石榴黑云片麻岩(样品18TZH49)位于造山带核心部分,其岩相学观察和相平衡模拟表明,其峰期和峰后变质阶段矿物组合分别为Sil+Grt+Pl+Bi+Qz+Ilm+Melt和St+Grt+Pl+Bi+Chl+Qz+Ilm,变质温压条件为720~780℃/5.9~6.9kbar和540~565℃/3~4.1kbar,从峰期到峰后记录了一个降温降压的顺时针P-T演化轨迹。锆石UPb年代学研究表明其退变质年龄为1851Ma。结合南、北辽河群其他变泥质岩研究工作,提出造山带北部北辽河群泥质岩经历低角闪岩相变质作用,以典型的巴罗式变质带为特征;造山带南部南辽河群经历角闪岩相至麻粒岩相变质作用,退变质特征明显。从构造角度来说,北辽河群受向北逆冲推覆构造影响,显示向龙岗基底的运动学特征;造山带核心部位的南、北辽河群直立褶皱发育,指示地壳强烈收缩过程;南辽河群受向南逆冲推覆构造影响,显示向南侧狼林陆块的运动学特征。变质变形及年代学共同指示,辽河群经历1.95~1.90Ga造山作用,构造增厚作用使不同类型岩石相互叠置并发生不同程度变质作用。随后,~1.85Ga发生造山后伸展作用,不同变质等级岩片剥露于地表。

关键词：前寒武纪造山带辽河群造山作用折返过程变质变形作用

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多视图立体三维重建中的孔洞修复算法

计算机辅助设计与图形学学报 2012年第12期24卷 1606-1613页

作者：吴晓军文飞温佩芝哈尔滨工业大学深圳研究生院深圳518055 深圳先进运动控制技术与现代自动化装备重点实验室深圳518055 桂林电子科技大学计算机科学与工程学院桂林541004

为了解决多视图立体三维重建算法不能很好地处理弱纹理或无纹理及高光区域的重建问题,提出一种基于可见外壳与多视图三维点云有机融合的多视图立体三维重建孔洞修复算法.该算法以可见外壳及多视图三维点云为输入,首先提取出可见外壳内... 详细信息

为了解决多视图立体三维重建算法不能很好地处理弱纹理或无纹理及高光区域的重建问题,提出一种基于可见外壳与多视图三维点云有机融合的多视图立体三维重建孔洞修复算法.该算法以可见外壳及多视图三维点云为输入,首先提取出可见外壳内满足点云稀疏度约束的叶节点,然后利用可见外壳法向量射线约束去除包裹在三维点云外层的叶节点,最后通过加入三维点云曲面曲率约束来消除点云中凹陷区域的影响.实验结果表明,文中算法有效地解决了物体缺乏纹理区域表面的孔洞修复问题,使得最终生成的三维网格模型完整和平滑,具有参数可调、易于实现的特点,对于不同的模型都具有非常好的鲁棒性.

关键词：孔洞修复多视图立体三维重建可见外壳点云稀疏度

Association of baseline hemoglobin A1c levels with bleeding in patients with non-ST-segment elevation acute coronary syndrome underwent percutaneous coronary intervention:insights of a multicenter cohort study from China

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Journal of Geriatric Cardiology 2022年第7期19卷 487-497页

作者： Hua-Lin FAN Li-Huan ZENG Peng-Yuan CHEN Yuan-Hui LIU Chong-Yang DUAN wen-fei HE Ning TAN Ji-Yan CHEN Peng-Cheng HE Department of Cardiology School of MedicineSouth China University of TechnologyGuangzhouChina Department of Cardiology Guangdong Cardiovascular InstituteGuangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhouChina Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhouChina The Second School of Clinical Medicine Southern Medical UniversityGuangzhouChina Department of Cardiology the Second People’s Hospital of Nanhai DistrictGuangdong Provincial People’s Hospital’s Nanhai HospitalFoshanChina De-partment of Biostatistics School of Public HealthSouthern Medical UniversityGuangzhouChina Department of Cardiology Heyuan People’s HospitalHeyuanChina

OBJECTIVE To investigate the association between baseline hemoglobin A1c(HbA1c)levels and bleeding in patients with non-ST-segment elevation acute coronary syndrome(NSTE-ACS)who underwent percutaneous coronary intervention(PCI).METHODS This observational cohort study enrolled 6283 consecutive NSTE-ACS patients undergoing PCI from January 1,2010 to December 31,*** on baseline HbA1c levels,the patients were divided into the group with HbA1c<7%(n=4740)and the group with HbA1c≥7%(n=1543).The primary outcomes are major bleeding(BARC grades 3-5)and all-cause death during *** Of patients enrolled,4705(74.9%)were male,and 2143(34.1%)had a history of diabetes mellitus,with a mean(SD)age of 64.13(10.32)*** median follow-up duration was 3.21 *** with the patients with HbA1c<7%,the risk of major bleeding events during follow-up was higher in patients with HbA1c≥7%(adjusted hazard ratio[HR]=1.57;95%con-fidence interval[CI]:1.01-2.44;P=0.044),while the risk of all-cause death during follow-up was not associated with the higher HbA1c levels(adjusted HR=0.88;95%CI:0.66-1.18;P=0.398).CONCLUSIONS Compared with the lower baseline HbA1c levels,the higher baseline HbA1c levels were associated with an increase in long-term bleeding risk in NSTE-ACS patients undergoing PCI,though higher baseline HbA1c levels were not associ-ated with the higher risk in all-cause death.

关键词： patients bleeding coronary

Impacts of angiotensin II on retinal artery changes in apolipoprotein E deficient mice

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International Journal of Ophthalmology(English edition) 2024年第1期17卷 16-24页

作者： Li-Hui Meng Shi-Yu Cheng He Chen Yue-Lin Wang wen-fei Zhang Huan Chen Xin-Yu Zhao You-Xin Chen Department of Ophthalmology Peking Union Medical College HospitalChinese Academy of Medical SciencesBeijing 100730China Key Lab of Ocular Fundus Diseases Chinese Academy of Medical SciencesBeijing 100730China

AIM:To investigate the impacts of angiotensin II(Ang II)on retinal artery changes in apolipoprotein E deficient(apoE^(-/-))***:ApoE^(-/-)male mice were infused by minipumps with Ang II at 1000 ng/kg·min(Ang II group)or saline(control group)for *** were underwent ophthalmic fundus examination on day 0,14,and 28 of *** examination,ribonucleic acid(RNA)sequencing and local Ang II measurement of retinas were ***:Ophthalmic fundus examination showed Ang II infusion promoted the formation of retinal arterial aneurysm-like lesions on day *** coherence tomography revealed the ganglion cell and inner plexiform layer(GCIPL)thickness in the control group was significantly thinner than that in Ang II group(P<0.001).Hematoxylin-eosin staining demonstrated diffused swelling of GCIPL layer and its disordered structure in Ang II *** electron microscopy showed Ang II infusion caused aggravation of atherosclerotic lesions,including increased swelling,roughness,disorganization of the retinal vasculature,and vacuoles ***-sequencing and gene ontology enrichment analysis demonstrated that the structure and function of cellular membrane might be disturbed and visual function might be compromised by Ang *** local level of Ang II was higher in Ang II infusion group but did not show significant differences compared to the control group(P=0.086).CONCLUSION:Ang II infusion promotes the formation of retinal arterial aneurysm-like lesions in apoE^(-/-)mice,causing aggravation of atherosclerotic lesions,more severe disorganization of the retinal vasculature and disturbance of the cellular membrane.

关键词： angiotensin II retinal artery aneurysm apoE^(-/-)mice

Locoregional extension patterns of nasopharyngeal carcinoma and suggestions for clinical target volume delineation

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Chinese Journal of Cancer 2012年第12期31卷 579-587页

作者： wen-fei Li Ying Sun Mo Chen Ling-Long Tang Li-Zhi Liu Yan-Ping Mao Lei Chen Guan-Qun Zhou Li Li Jun Ma State Key Laboratory of Oncology in South China Department of Radiation Oncology Sun Yat-sen University Cancer Center Imaging Diagnosis and Interventional Center Sun Yat-sen University Cancer Center

Clinical target volume (CTV) delineation is crucial for tumor control and normal tissue protection. This study aimed to define the locoregional extension patterns of nasopharyngeal carcinoma (NPC) and to improve CTV delineation. Magnetic resonance imaging scans of 2366 newly diagnosed NPC patients were reviewed. According to incidence rates of tumor invasion, the anatomic sites surrounding the nasopharynx were classified into high-risk (>30%), medium-risk (5%-30%), and low-risk (<5%) groups. The lymph node (LN) level was determined according to the Radiation Therapy Oncology Group guidelines, which were further categorized into the upper neck (retropharyngeal region and level Ⅱ), middle neck (levels Ⅲ and Va), and lower neck (levels Ⅳ and Vb and the supraclavicular fossa). The high-risk anatomic sites were adjacent to the nasopharynx, whereas those at medium- or low-risk were separated from the nasopharynx. If the high-risk anatomic sites were involved, the rates of tumor invasion into the adjacent medium-risk sites increased; if not, the rates were significantly lower (P < 0.01). Among the 1920 (81.1%) patients with positive LN, the incidence rates of LN metastasis in the upper, middle, and lower neck were 99.6% , 30.2%, and 7.2%, respectively, and skip metastasis happened in only 1.2% of patients. In the 929 patients who had unilateral upper neck involvement, the rates of contralateral middle neck and lower neck involvement were 1.8% and 0.4%, respectively. Thus, local disease spreads stepwise from proximal sites to distal sites, and LN metastasis spreads from the upper neck to the lower neck. Individualized CTV delineation for NPC may be feasible.

关键词：鼻咽癌局部区域靶区临床圈定解剖部位磁共振成像肿瘤学

Advanced oxidation protein products induce monocyte chemoattractant protein-1 expression via p38 mitogen-activated protein kinase activation in rat vascular smooth muscle cells

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Chinese Medical Journal 2006年第13期119卷 1088-1093页

作者： PENG Kan-fu WU Xiong-fei ZHAO Hong-wen SUN Yan Department of Nephrology Southwest Hospital Third Military Medical University Chongqing 400038 China

Background Advanced oxidation protein products （AOPPs） are new uremic toxins reported by Witko-Sarsat in 1996, which are associated with the pathogenesis of atherosclerosis. However, the mechanisms by which AOPPs enhance atherosclerosis have not been fully understood. Monocyte chemoattractant protein-1 （MCP-1） is a chemokine which stimulates migration of monocytes and plays a critical role in the development of atherosclerosis. In this study, we investigated the effect of AOPPs on MCP-1 expression in cultured vascular smooth muscle cells （VSMCs）.

关键词： atherosclerosis advanced oxidation protein products monocyte chemoattractant protein-1 mitogen-activated protein kinase myocytes, smooth muscle

Laparoscopic liver resection under hemihepatic vascular inflow occlusion using the lowering of hilar plate approach

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Hepatobiliary & Pancreatic Diseases International 2014年第5期13卷 508-512页

作者： Ying-Jun Chen Zuo-Jun Zhen Huan-Wei Chen Eric CH Lai fei-wen Deng Qing-Han Li Wan Yee Lau Department of Liver Surgery The First People's Hospital of Foshan Faculty of Medicine The Chinese University of Hong Kong

BACKGROUND： With advances in technology, laparoscopic liver resection is widely accepted. Laparoscopic liver resection under hemihepatic vascular inflow occlusion has advantages over the conventional total hepatic inflow occlusion using the Pringle＇s maneuver, especially in patients with ***： From November 2011 to August 2012, eight consecutive patients underwent laparoscopic liver resection under hemihepatic vascular inflow occlusion using the lowering of hilar plate approach with biliary bougie ***： The types of liver resection included right hepatectomy（n1）, right posterior sectionectomy（n1）, left hepatectomy and common bile duct exploration（n1）, segment 4b resection（n1）, left lateral sectionectomy（n2）, and wedge resection（n2）. Four patients underwent right and 4 left hemihepatic vascular inflow occlusion. Four patients had cirrhosis. The mean operation time was 176.3 minutes. The mean time taken to achieve hemihepatic vascular inflow occlusion was 24.3minutes. The mean duration of vascular inflow occlusion was54.5 minutes. The mean intraoperative blood loss was 361 *** patient required blood transfusion. Postoperatively, one patient developed bile leak which healed with conservative treatment. No postoperative liver failure and mortality occurred. The mean hospital stay of the patients was 7 ***： Our technique of hemihepatic vascular inflow vascular occlusion using the lowering of hilar plate approachwas safe, and it improved laparoscopic liver resection by minimizing blood loss during liver parenchymal transection.

关键词： laparoscopic liver resection hepatectomy vascular control liver neoplasm hilar plate

Effects of Vitisin B on Osteoblastogenesis

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Effects of Vitisin B on Osteoblastogenesis