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Healthcare-associated Pneumonia： Clinical Features and Retrospective Analysis Over 10 Years

Chinese Medical Journal 2015年第20期128卷 2707-2713页

作者： fei qi guo-xin zhang dan-yang she zhi-xin liang ren-tao wang zhen yang liang-an chen jun-chang cui Department of Respiratory Medicine Chinese People's Liberation Army General Hospital Beijing 100853 China

Background： Healthcare-associated pneumonia （HCAP） is associated with drug-resistant pathogens and high mortality, and there is no clear evidence that this is due to inappropriate antibiotic therapy. This study was to elucidate the clinical features, pathogens, therapy, and outcomes of HCAP, and to clarify the risk factors for drug-resistant pathogens and prognosis. Methods： Retrospective observational study among hospitalized patients with HCAP over 10 years. The primary outcome was 30-day all-cause hospital mortality after admission. Demographics （age, gender, clinical features, and comorbidities）, dates of admission, discharge and/or death, hospitalization costs, microbiological results, chest imaging studies, and CURB-65 were analyzed. Antibiotics, admission to Intensive Care Unit （ICU）, mechanical ventilation, and pneumonia prognosis were recorded. Patients were dichotomized based on CURB-65 （lowvs. high-risk）. Results： Among 612 patients （mean age of 70.7 years）, 88.4% had at least one comorbidity. Commonly detected pathogens were Acinetobacter baumannii, Pseudomonas aeruginosa, and coagulase-negative staphylococci. Initial monotherapy with 13-1actam antibiotics was the most common initial therapy （50%）. Mean age, length of stay, hospitalization expenses, ICU admission, mechanical ventilation use, malignancies, and detection rate for P. aeruginosa, and Staphylococcus aureus were higher in the high-risk group compared with the low-risk group. CURB-65 ≥3, malignancies, and mechanical ventilation were associated with an increased mortality. Logistic regression analysis showed that cerebrovascular diseases and being bedridden were independent risk factors for HCAR Conclusion： Initial treatment of HCAP with broad-spectrum antibiotics could be an appropriate approach. CURB-65 〉3, malignancies, and mechanical ventilation may result in an increased mortality.

关键词： Acinetobacter Baumannii Antibiotic Resistance Community-acquired Pneumonia CURB-65 Healthcare-associatedPneumonia Pseudomonas Aeruginosa

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Data release of the LAMOST pilot survey

引用

Research in Astronomy and Astrophysics 2012年第9期12卷 1243-1246页

作者： A-Li Luo Hao-Tong zhang Yong-Heng Zhao Gang Zhao Xiang-Qun cui guo-Ping Li Yao-Quan Chu Jian-Rong Shi Gang wang Jian-Nan zhang Zhong-Rui Bai Xiao-Yan chen Feng-fei wang Yan-xin guo Jian-jun chen Bing Du Xiao Kong Ya-Juan Lei Yin-Bi Li Yi-Han Song Yue Wu Yan-Xia zhang xin-Lin Zhou Fang Zuo Peng Du Lin He Wen Hou Yi-qiao Dong Jian Li Guang-Wei Li Shuang Li Jing Song Yuan Tian Meng-xin wang Yong-Hui Hou zhi-Ying Huo Hong-Zhuan Hu Ning-sheng Hu Zhong-Wen Hu Lei Jia Fang-Hua Jiang Xiang Jiang Zi-Bo Jiang Ge Jin Ai-Hua Li qi Li Yin-Dun Mao zheng-Hong Tang qing-sheng tao liang-Ping Tu Da-qing wang dan wang Jian-Ping wang Lei wang Shou-Guan wang Shu-qing wang Ya-Nan wang You wang Yue-fei wang Ming-zhi Wei Xiang-Xiang Xue Xiao-zheng xing Ling-Zhe Xu xin-qi Xu Yan Xu De-Hua yang Shi-Hai yang zheng-qiu Yao Yong Yu Hui Yuan Chao Zhai En-Peng zhang Jing zhang Li-Ping zhang Weizhang Yong zhang zhen-Chao zhang Ming Zhao Fang Zhou Yong-Tian Zhu Jie Zhu Si-cheng Zou National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China lal @ lamost o rg Nanjing Institute of Astronomical Optics and Technology National Astronomical ObservatoriesChinese Academy of Sciences Nanjing 210042 China University of Science and Technologyof China Hefei 230026 China Shanghai Astronomical Observatory Chinese Academy of Sciences Shanghai 200030 China Institute of Architecture Design and Research Chinese Academy of Sciences Beijing 100190China

This paper describes the data release of the LAMOST pilot survey, which includes data reduction, calibration, spectral analysis, data products and data access. The accuracy of the released data and the information about the FITS headers of spectra are also introduced. The released data set includes 319 000 spectra and a catalog of these objects.

关键词： techniques: spectroscopic survey — data reduction — data release

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