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Key knowledge gaps for One Health approach to mitigate nanoplastic risks

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Eco-Environment & Health 2022年第1期1卷 11-22页

作者： fei dang Qingyu Wang Yingnan Huang Yujun Wang Baoshan Xing Key Laboratory of Soil Environment and Pollution Remediation Institute of Soil ScienceChinese Academy of SciencesNanjing 210008China University of Chinese Academy of Sciences Beijing 100049China Stockbridge School of Agriculture University of MassachusettsAmherstMA 01003United States

There are increasing concerns over the threat of nanoplastics to environmental and human ***,multidisciplinary barriers persist between the communities assessing the risks to environmental and human *** a result,the hazards and risks of nanoplastics remain ***,we identify key knowledge gaps by evaluating the exposure of nanoplastics in the environment,assessing their bio-nano interactions,and examining their potential risks to humans and the *** suggest considering nanoplastics a complex and dynamic mixture of polymers,additives,and contaminants,with interconnected risks to environmental and human *** call for comprehensive integration of One Health approach to produce robust multidisciplinary evidence to nanoplastics threats at the planetary *** there are many challenges,this holistic approach incorporates the relevance of environmental exposure and multi-sectoral responses,which provide the opportunity to identify the risk mitigation strategies of nanoplastics to build resilient health systems.

关键词： Nanoplastics Environmental exposure Human health One health Risk mitigation

ZmMYC7转录因子调控玉米抗病相关功能的初步研究

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农业生物技术学报 2024年第1期32卷 1-10页

作者：王永桂李薇崔婷茹张福源杨文皓许荡非邢继红曹宏哲董金皋河北农业大学华北作物改良与调控国家重点实验室/河北省植物生理与分子病理学重点实验室保定市气象局张家口市林业工作总站

玉米(Zea mays)是全球最重要的粮食作物之一，病原菌引起的玉米病害直接影响玉米生产，导致巨大的经济损失。转录因子MYC2在植物抗病领域发挥重要作用。本实验室前期获得拟南芥(Arabidopsis thaliana) AtMYC2在玉米中的同源基因ZmMYC7(Z... 详细信息

玉米(Zea mays)是全球最重要的粮食作物之一，病原菌引起的玉米病害直接影响玉米生产，导致巨大的经济损失。转录因子MYC2在植物抗病领域发挥重要作用。本实验室前期获得拟南芥(Arabidopsis thaliana) AtMYC2在玉米中的同源基因ZmMYC7(Zm00001d030028)。为了探究转录因子ZmMYC7在调控玉米抗病过程中的功能，本研究检测ZmMYC7突变体对4种玉米真菌病害的敏感性，利用qRT-PCR技术检测ZmMYC7突变对病程相关蛋白(pathogenesis-related protein, PR)基因表达的影响。结果显示，ZmMYC7与高粱(Sorghum bicolor) SbMYC2的同源性最高(90%);ZmMYC7在玉米的叶和花药中表达水平较高，紫外照射和禾谷镰刀菌(Fusarium graminearum)侵染会上调ZmMYC7基因表达；ZmMYC7突变后，玉米对叶和茎部病害的敏感性显著增加，病程相关蛋白基因ZmPRs的表达显著下调(P<0.01)。上述结果提示ZmMYC7可能在玉米抗病过程中发挥作用。本研究为深入解析ZmMYC7调控玉米抗病的分子机制提供基础资料。

关键词： ZmMYC7 病程相关蛋白(PR) 病原体禾谷镰刀菌转录因子

Photoinduced generation of alkyl and phthalimide nitrogen radicals from N-hydroxyphthalimide esters for the synthesis of benzophenone-type bioisosteres

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Science China Chemistry 2024年第10期67卷 3389-3396页

作者： fei Li Jianyang Dong Huijuan Liao Jiayi dang Xuechen Zhou Yuying Wang Chenya Wang Qin Jiang Gang Li Dong Xue Key Laboratory of Applied Surface and Colloid Chemistry Ministry of Education and School of Chemistry and Chemical EngineeringShaanxi Normal University

N-Hydroxyphthalimide（NHPI） esters have emerged as powerful sources of alkyl radicals generated by single-electron transfer,but homolysis of NHPI ester to produce an alkyl radical and a phthalimide nitrogen radical is still in its infancy. In this study, we developed a light-induced method for generation of alkyl and phthalimide nitrogen radicals from NHPI esters and subsequent reactions of the radicals with [1.1.1]propellane and aryl aldehydes for rapid generation of bicycle [1.1.1]pentane ketones. This method does not require metals or photosensitizers, features a broad substrate scope（90 examples） and excellent functional group tolerance, and can be used for the functionalization of structurally complex natural products and drugs. Mechanistic investigations indicate that the reaction involves photoinduced homolytic cleavage of the Cs2CO3-NHPI ester complex to produce alkyl and phthalimide nitrogen radicals and subsequent hydrogen atom transfer between the phthalimide nitrogen radical and the aldehyde to generate an acyl radical.

关键词： phthalimide nitrogen radicals aryl aldehydes hydrogen atom transfer bicycle[1.1.1]pentane ketones bioisosteres

Microstructure and Mechanical Behavior of Mg-Based Bimetal Plates with High Formability Sleeve by Co-extrusion

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Acta Metallurgica Sinica(English Letters) 2024年第3期37卷 499-512页

作者： Yue-Hui dang Sheng-Lin Liu Xiao-Lei Ai Xiao-Wei Feng Bo Feng Zhuo Tian Ying-fei Lin Huan-Tao Chen Kai-Hong Zheng School of Materials Science and Engineering Chang’an UniversityShaanxi 710064China Guangdong Key Laboratory of Metal Toughening Technology and Application Institute of New MaterialsGuangdong Academy of SciencesGuangzhou 510650China

In this study,microstructure and mechanical behavior of two types of Mg-based bimetal plates with a high formability sleeve were systematically studied,with a great emphasis on the effect of the interface characteristic and the sleeve fraction on the plasticity of composite *** rule of mixtures(ROM)for elongation was also *** results show that when there is no or thin diffusion layer with thickness of about 3μm,Mg-based bimetal plates have a good plasticity with elongation of about 19-24%,and the ROM predicted elongations are very close to the experimental *** contrast,with a diffusion layer about 95-155μm thick,Mg-based bimetal plates exhibit a poor plasticity with elongation of about 11-17%,and the experimental elongations largely deviate from the ROM *** plasticity of Mg-based bimetal plates increases with increasing sleeve *** study provides new insights on the plastic deformation of Mg-based bimetal composites with a high formability sleeve.

关键词： Mg-based composites Co-extrusion Microstructure Mechanical behavior Plastic deformation

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植物介导金属纳米颗粒合成的研究进展

农业资源与环境学报 2022年第4期39卷 664-672页

作者：金季也吴甘霖党菲安庆师范大学化学化工学院安徽安庆246133 安庆师范大学生命科学学院安徽安庆246133 中国科学院南京土壤研究所土壤环境与污染修复重点实验室南京210008

随着纳米科技的快速发展,人工合成的金属纳米颗粒已在农业生产、生物医药、个人消费品等领域广泛应用。同时,越来越多研究表明植物也能介导金属纳米颗粒的合成。这些研究为制备金属纳米颗粒提供了新思路,但是,多数研究只局限于植物合成... 详细信息

随着纳米科技的快速发展,人工合成的金属纳米颗粒已在农业生产、生物医药、个人消费品等领域广泛应用。同时,越来越多研究表明植物也能介导金属纳米颗粒的合成。这些研究为制备金属纳米颗粒提供了新思路,但是,多数研究只局限于植物合成方法的表观描述,缺乏对过程及机理的深入研究。这不仅阻碍了金属纳米颗粒与植物相互作用的理论认知,还限制了植物合成方法的大规模应用。本文总结了近年来植物体内金属纳米颗粒的鉴别与表征方法及植物合成纳米材料的应用,重点对植物合成纳米颗粒的过程进行了梳理,发现有机酸、还原性糖类、蛋白质等生物成分都会参与纳米颗粒的生成过程。今后需研发更多的表征手段,以原位技术全面揭示植物合成金属纳米颗粒的机制。

关键词：金属纳米颗粒植物表征合成过程

A Study on the Changes and Development of Water Resources in Urumqi

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A Study on the Changes and Development of Water Resources in...

2012 China Functional Materials Technology and Industry Forum

作者： Zhi-Jian Wang fei dang College of Economic and Management Xinjiang University

Using Excel software,this paper analyzes the changes of water resources in recent 10 years in the area of Urumqi,and it discovers that water resources per capital in Urumqi is declining;the annual precipitation is ascending in its totality though there is fluctuation;the amount of water usage is rising evidently and there is an increase tendency in the apects of lacking water resources and imbalance between supply and *** main reasons that cause the above situation are the serious waste and low utilization of water resources;extensive use and over-development of water resources in some parts of Urumqi;unreasonable industrial distribution and lack of the comprehensive and unitied diministration of water *** with these problems,the paper tries to put some suggestions from the point view of regional sustainable development.

关键词： water resources changes development Urumqi

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老旧小区消防安全管理现状及防火措施

今日消防 2023年第7期8卷 47-49页

作者：党飞宝鸡市消防救援支队陕西宝鸡721000

近年来,我国城市中存在的老旧小区消防安全问题依然较为突出,老旧小区中生活着较大数量的中老年群体,这部分人群行动较为迟缓,对于突发事件的应对能力不足,再加上老旧小区配置的消防设施不够完善,很有可能在发生火灾事故时造成较为严重... 详细信息

近年来,我国城市中存在的老旧小区消防安全问题依然较为突出,老旧小区中生活着较大数量的中老年群体,这部分人群行动较为迟缓,对于突发事件的应对能力不足,再加上老旧小区配置的消防设施不够完善,很有可能在发生火灾事故时造成较为严重的后果。因此,对老旧小区的基本特点进行了分析,针对老旧小区消防安全管理的现状做了简要论述,并针对性提出了老旧小区的防火措施,旨在为相关行业从业人员提供经验借鉴和帮助,助力老旧小区消防管理工作有序展开。

关键词：老旧小区消防安全消防设施防火策略安全管理

超声检查在产褥期下肢深静脉血栓形成的诊断价值

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血栓与止血学 2022年第3期28卷 479-481页

作者：党飞飞曹莉延安市中医医院超声医学科延安716000

目的评估超声检查在产褥期下肢深静脉血栓(DVT)形成的诊断价值。方法回顾性选取2018年3月至2021年3月于本院就诊的160例疑似下肢DVT产褥期患者的临床资料。均接受彩色多普勒超声,以下肢深静脉造影检查结果为金标准,用Kappa检验超声诊断... 详细信息

目的评估超声检查在产褥期下肢深静脉血栓(DVT)形成的诊断价值。方法回顾性选取2018年3月至2021年3月于本院就诊的160例疑似下肢DVT产褥期患者的临床资料。均接受彩色多普勒超声,以下肢深静脉造影检查结果为金标准,用Kappa检验超声诊断与造影检查结果的一致性。结果造影结果显示,160例疑似下肢DVT患者中,93例诊断为阳性。彩色多普勒超声结果显示,160例疑似下肢DVT患者中,95例诊断为阳性,65例诊断为阴性。彩色多普勒超声鉴别下肢DVT的灵敏度、特异度、阳性预测值、阴性预测值和准确率分别为96.77%(90/93)、92.54%(62/67)、94.74%(90/95)、95.38%(92/95)、95.00%(152/160);Logistic回归性分析结果显示,分娩方式和长期卧床史均为影响产褥期下肢DVT形成独立危险因素(P<0.05)。结论彩色多普勒超声可准确诊断患者产褥期下肢DVT,可为产褥期下肢DVT患者提高重要临床指导,体质量指数、剖宫产和长期卧床史均为产褥期下肢DVT形成的危险因素。

关键词：超声检查产褥期下肢深静脉血栓

超声检测在小儿川崎病冠状动脉血栓的应用及临床特性

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血栓与止血学 2022年第2期28卷 233-234页

作者：曹莉党飞飞延安市中医医院超声医学科延安716000

目的探讨超声检测在小儿川崎病(KD)冠状动脉血栓的应用。方法以120例KD患儿为对象,均接受超声心动图检查并进行为期12个月的随访。结果 120例KD患儿中第1次检查结果显示32例(26.67%)患儿存在冠状动脉病变。32例患儿中30例(93.75%)为冠... 详细信息

目的探讨超声检测在小儿川崎病(KD)冠状动脉血栓的应用。方法以120例KD患儿为对象,均接受超声心动图检查并进行为期12个月的随访。结果 120例KD患儿中第1次检查结果显示32例(26.67%)患儿存在冠状动脉病变。32例患儿中30例(93.75%)为冠状动脉异常脉扩张(CAD),CA/AO比值0.15~0.30,双侧冠状动脉起始处均受累10例(33.33%),左侧冠状动脉扩张15例(50.00%),右侧冠状动脉扩张5例(16.67%),超声检查显示扩张的冠脉管壁存在增厚情况,内部回声不均。2例(6.25%)患儿为右侧冠状动脉起始段动脉瘤形成冠状动脉呈现球囊样扩张。第二次超声检查结果显示22例(18.33%)存在冠状动脉病变。其中17例(77.27%)为CAD,5例(22.73%)为冠状动脉瘤(CAA)。对患儿进行随访发现,发病后3、6、12个月冠状动脉CAD及CAA两种类型病变逐渐减少,2例CAA患儿随访12个月后转变为CAD,其余30例患儿冠脉病变症状消失。结论超声心动图检测KD患儿冠脉病变的敏感性较高,并可用于KD患儿冠脉病变的随访观察。

关键词：超声小儿川崎病冠状动脉血栓