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Topography,structural and exhumation history of the Admiralty Mountains region,northern Victoria Land,Antarctica

Geoscience Frontiers 2020年第5期11卷 1841-1858页

作者： Maria Laura Balestrieri Valerio Olivetti federico rossetti Cecile Gautheron Silvia Catto Massimiliano Zattin Istituto di Geoscienze e Georisorse Consiglio Nazionale delle RicercheSede Secondaria Firenzevia G.La Pira 450121FirenzeItaly Dipartimento di Geoscienze Universita di PadovaPadovaItaly Dipartimento di Scienze Universita degli Studi Roma 3RomaItaly GEOPS Univ.Paris SudCNRS Universite Paris-Saclay91405OrsayFrance

The Admiralty Mountains region forms the northern termination of the northern Victoria Land,*** quantitative data are available to reconstruct the Cenozoic morpho-tectonic evolution of this sector of the Antarctic plate,where the Admiralty Mountains region forms the northern termination of the western shoulder of the Mesozoic-Cenozoic West Antarctica Rift *** this study we combine new low-temperature thermochronological data(apatite fission-track and(U-Th-Sm)/He analyses)with structural and topography *** regional pattern of the fission-track ages shows a general tendency to older ages(80-60 Ma)associated with shortened mean track-lengths in the interior,and younger fission-track ages clustering at 38-26 Ma with long mean track-lengths in the coastal *** from other regions of Victoria Land,the younger ages are found as far as 50-70 km *** grain apatite(U-Th-Sm)/He ages cluster at 50-30 Ma with younger ages in the coastal *** analysis reveals that the Admiralty Mountains has high local relief,with an area close to the coast,180 km long and 70 km large,having the highest local relief of>2500 *** coincides with the location of the youngest fission-track *** shape of the area with highest local relief matches the shape of a recently detected low velocity zone beneath the northern TAM,indicating that high topography of the Admiralty Mountains region is likely sustained by a mantle thermal *** used the obtained constraints on the amount of removed crustal section to reconstruct back-eroded profiles and calculate the erosional load in order to test flexural uplift *** found that our back-eroded profiles are better reproduced by a constant elastic thickness of intermediate values(Te=20-30 km).This suggests that,beneath the Admiralty Mountains,the elastic properties of the lithosphere are different with respect to other TAM sectors,likely due to a stationary Cenozoic upper mantle thermal an

关键词： Antarctica Thermochronology Transantarctic mountains Rift margin uplift

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Coupling of bioelectrochemical toluene oxidation and trichloroethene reductive dechlorination for single-stage treatment of groundwater containing multiple contaminants

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Environmental Science and Ecotechnology 2022年第3期11卷 32-39页

作者： Carolina Cruz Viggi Matteo Tucci Marco Resitano Simona Crognale Maria Letizia Di Franca Simona rossetti federico Aulenta Water Research Institute(IRSA) National Research Council(CNR)Via Salaria Km 2930000015MonterotondoRMItaly

Bioremediation of groundwater contaminated by a mixture of aromatic hydrocarbons and chlorinated solvents is typically challenged because these contaminants are degraded via distinctive oxidative and reductive pathways,thus requiring different amendments and redox ***,we provided the proof-of-concept of a single-stage treatment of synthetic groundwater containing toluene and trichloroethene(TCE)in a tubular bioelectrochemical reactor,known as a“bioelectric well”.Toluene was degraded by a microbial bioanode(up to 150 mmol L^(-1) d^(-1))with a polarized graphite anode(t0.2 V ***)serving as the terminal electron *** electric current deriving from microbially-driven toluene oxidation resulted in(abiotic)hydrogen production(at a stainless-steel cathode),which sustained the reductive dechlorination of TCE to less-chlorinated intermediates(i.e.,cis-DCE,VC,and ETH),at a maximum rate of 500 meq L^(-1) d^(-1),in the bulk of the reactor.A phylogenetic and functional genebased analysis of the“bioelectric well”confirmed the establishment of a microbiome harboring the metabolic potential for anaerobic toluene oxidation and TCE reductive ***,Toluene degradation and current generation were found to be rate-limited by external mass transport phenomena,thus indicating the existing potential for further process optimization.

关键词： Bioelectric well Dehalococcoides mccartyi Electrobioremediation Groundwater remediation Toluene Trichloroethene

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Cytoreductive surgery and HIPEC after neoadjuvant chemotherapy for advanced epithelial ovarian cancer

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World Journal of Obstetrics and Gynecology 2013年第4期2卷 167-175页

作者： Marco Lotti Luisa Maria Busci Luca Campanati Fausto Catena federico Coccolini Naoual Bakrin Pierandrea De Iaco Giorgio Ercolani Giuseppe Grosso Michele Pisano Elia Poiasina Diego rossetti Martina Rossi Claudio Zamagni Paolo Bertoli Antonio Daniele Pinna Luigi Frigerio Luca Ansaloni Unit of General Surgery 1 Papa Giovanni XXIII Hospital 24128 Bergamo Italy Unit of Gynecology and Obstetrics Papa Giovanni XXIII Hospital 24128 Bergamo Italy Unit of General Surgery St.Orsola-Malpighi University Hospital 40138 Bologna Italy Department of Gynecology Lyon Sud Hospital69310 Pierre Benite France Unit of Gynecology and Obstetrics St.Orsola-Malpighi University Hospital V40138 Bologna Italy Medical Oncology St.Orsola-Malpighi University Hospital 40138 Bologna Italy

AIM: To reduce postoperative complications and to make possible an optimal cytoreduction, neoadjuvant chemotherapy(NACT) followed by interval debulking surgery has been applied with encouraging results. METHODS: Between December 2009 and February 2012, patients with stage ⅢC-Ⅳ epithelial ovarian cancer(EOC) underwent diagnostic laparoscopy, to assess the feasibility of optimal debulking surgery. The modifi ed Fagotti score was applied to assess the feasibility of resection with zero residual tumor. Patients who were not candidate for upfront debulking surgery were submitted to NACT, then reassessed according to the RECIST 1.1 criteria and submitted to cytoreductive surgery(CRS) and hyperthermic intraperitoneal chemotherapy(HIPEC) if they showed clinical response or stable disease. The remaining cycles of adjuvant systemic chemotherapy(ASCT) were administered postoperatively, to complete 6 cycles of systemic ***: Nine patients were included. Clinical response to NACT was complete in 3 patients and partial in 5 patients; one patient had stable disease. All patients underwent CRS resulting in CC0 disease prior to HIPEC. Average operative time was 510 min. Average intensive care unit stay was 2 d. Average postoperative hospital stay was 25 d. No postoperative mortality was observed. One patient experienced pelvic abscess. One patient refused ASCT. The remaining 8 patients started ASCT. Average time to chemotherapy was 36 d. All patients are alive, with an average follow up of 11 mo. Eight patients are disease-free at follow ***: HIPEC after CRS for advanced EOC is feasible with acceptable morbidity and mortality. NACT may increase the chance for achieving complete cytoreduction. Phase 3 studies are needed to determine the effects of HIPEC on survival.

关键词： Peritoneal carcinomatosis Ovarian cancer Cytoreductive surgery Intraperitoneal chemotherapy Hyperthermic intraperitoneal chemotherapy Hyperthermia

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Unilateral post-chemotherapy robot-assisted retroperitoneal lymph node dissection in Stage II non-seminomatous germ cell tumor:A tertiary care experience

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Asian Journal of Urology 2023年第4期10卷 440-445页

作者： Dario Franzese Antonio Tufano Alessandro Izzo Raffaele Muscariello Giovanni Grimaldi Giuseppe Quarto Luigi Castaldo Sabrina rossetti Savio Domenico Pandolfo Sonia Desicato Paola Del Prete Matteo Ferro Sandro Pignata Sisto Perdonà Department of Urology National Cancer InstitutePascale FoundationNaplesItaly Urology Unit Department of Maternal-Child and Urological Sciences“Sapienza”UniversityRomeItaly Department of Neurosciences Science of Reproduction and OdontostomatologyUniversity of Naples Federico IINaplesItaly Scientific Directorate Istituto Nazionale Tumori di NapoliIRCCS“G.Pascale”NaplesItaly Division of Urology European Institute of Oncology(IEO)IRCCSMilanItaly Division of Medical Oncology Department of Uro-Gynaecological OncologyIstituto Nazionale per lo Studio e la Cura dei Tumori“Fondazione G.Pascale”IRCCSNaplesItaly

Objective Post-chemotherapy retroperitoneal lymph node dissection(PC-RPLND)represents an integral component of the management of patients with non-seminomatous germ cell tumor(NSGCT).Modified templates have been proposed to minimize the surgical morbidity of the ***,the implementation of robotic surgery in this setting has been *** report our experience with unilateral post-chemotherapy robot-assisted retroperitoneal lymph node dissection(PC-rRPLND)for clinical Stages IIA and IIB *** A retrospective single institution review was performed including 33 patients undergoing PC-rRPLND for Stages IIA and IIB NSGCTs between January 2015 and February *** orchiectomy,patients were scheduled for chemotherapy with three cycles of *** with a residual tumor of<5 cm and an ipsilateral metastatic disease on pre-and post-chemotherapy CT scans were eligible for a unilateral template in absence of rising tumor *** statistics were provided for demographics,clinical characteristics,intraoperative and postoperative ***,oncological,and functional outcomes were *** Overall,7(21.2%)patients exhibited necrosis or fibrosis;14(42.4%)had mature teratoma;and 12(36.4%)had viable tumor at final *** median lymph node size at surgery was 25(interquartile range[IQR]21-36)*** operative time was 180(IQR 165-215)min and no major postoperative complications were *** ejaculation was preserved in 75.8%of *** follow-up was 26(IQR 19-30)months and a total of three recurrences were *** PC-rRPLND is a reliable and technically reproducible procedure with safe oncological outcomes and acceptable postoperative ejaculatory function in well selected patients with NSGCTs.

关键词： Testis tumor Robot-assisted retroperitoneal lymph node dissection Retroperitoneal lymph node dissection Non-seminomatous germ cell tumor Unilateral dissection Modified template Post-chemotherapy

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