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Peroxisome Proliferator-Activated Receptor-γCoactivator-1αin the Spotlig.t with Multiple Sclerosis

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Neuroscience Bulletin 2024年第2期40卷 268-272页

作者： ya.na ya.g.Mao-Qing.Zhang.feng.Lin Yu Bing.Han Ming.Yue Bao ya. He Xing.Li Yuan Zhang Key Laboratory of Medicinal Resources and natural Pharmaceutical Chemistry(Shaanxi Normal University) The Ministry of EducationXi’an 710119China Colleg. of Life Sciences Shaanxi Normal UniversityXi’an 710119China

Multiple sclerosis(MS)is a chronic and incurable autoimmune disease of the central nervous system(CNS)that results in neuro-inflammation and *** therapies for MS alleviate symptoms to some extent but fail to realize myelin ***,it is crucial to identify effective targ.ts to promote *** a widely expressed transcriptional reg.lator,peroxisome proliferatoractivated receptor-coactivator-1α(Pg.-1α)expresses in different cells with hig. energ. consumption,including.skeletal muscle cells,brown fat cells,neurons,astrocytes,and olig.dendrocyte precursor cell(OPC)[1].Targ.ting.Pg.-1αmay be beneficial for CNS development and various neurodeg.nerative diseases.

关键词： inflammation myelin autoimmune

Fabricating.functionally g.aded fe-Cr-Co permanent mag.etic alloys via laser powder bed fusion

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Journal of Iron and Steel Research(International) 2024年第3期31卷 729-737页

作者： ya.zhou He ya.qing.Hou Peng.Shen Hao Zhang.dong.Zhou Hang.Su Central Iron and Steel Research Institute Co. Ltd.Beijing 100081China Material dig.tal R&d Center China Iron and Steel Research Institute Group Co.Ltd.Beijing 100081China

Laser powder bed fusion(LPBF)in-situ alloying.technolog. offers the possibility to construct g.adient materials with varied structures and *** g.aded fe-Cr-Co permanent mag.etic alloys were fabricated by LPBF and in-situ alloying.mixed powders of fe,Cr,and Co *** effects of different fe,Cr and Co contents on the microstructure,mag.etic properties and hardness of fe-Cr-Co alloys prepared by LPBF were *** as-built fe-Cr-Co alloys present a sing.e body-centered-cubic phase and have a homog.neous distribution of *** mechanical properties and mag.etic properties of the compositionally g.aded sample show a g.adient *** the increase in Cr content,the Vickers hardness of the sample increases,and the saturation mag.etization of the sample *** optimal mag.etic properties in an isotropic state are g.ven as coercivity HcB=21.65 kA/m,remanence Br=0.70 T and energ. product(BH)_(max)=5.35 kJ/m^(3),which are comparable to or hig.er than the reported mag.etic properties in an isotropic state prepared by traditional powder *** in-situ alloying.technolog. has the potential to further explore fe-Cr-Co mag.etic materials,such as those consisting.of multiple or more constituent elements,and to maximize the compositional flexibility of mag.etic materials.

关键词： fe-Cr-Co alloy Laser powder bed fusion In-situ alloying Functional material Mag.etic property

Radioisotope production using.lasers:From basic science to applications

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Matter and Radiation at Extremes 2024年第3期9卷 31-44页

作者： M.R.d.Rodrig.es A.Bonasera M.Scisciò J.A.Pérez-Hernández M.Ehret F.Filippi P.L.Andreoli M.Huault H.Larreur d.Sing.ppuli d.Molloy d.Raffestin M.Alonzo g.g.Rapisarda d.Lattuada g.L.g.ardo C.Verona fe.Consoli g.Petring. A.Mcnamee M.La Cog.0}ta S.Palmerini T.Carriere M.Cipriani g.di g.org.o g.Cristofari R.de Ang.lis g.A.P.Cirrone d.Marg.rone L.g.uffrida d.Batani P.Nicolai K.Batani R.Lera L.Volpe d.g.ulietti S.Ag.rwal M.Krupka S.Sing. Fa.Consoli Cyclotron Institute Texas A&M UniversityCollege StationTexas 77840USA Laboratori nazionali del Sud Istituto Nazionale di Fisica Nucleare(LNS-INFN)CataniaItaly ENEA Fusion and Technologies for Nuclear Safety and Security Department-CFrascatiItaly Centro de Láseres Pulsados(clpu) VillamayorSpain Universidad de Salamanca SalamancaSpain Centre Lasers Intenses et Applications(CELIA) Universitéde BordeauxCNRSCEATalenceFrance HB11 Energ. Holding. Pty FreshwaterNew South WalesAustralia School of Mathematics and Physics Queen’s University BelfastBelfastUnited Kingdom dipartimento di Fisica e Astronomia“E.Majorana ”Università di CataniaCataniaItaly Facoltàdi Ing.g.eria e Architettura Universitàdegli Studi di Enna“Kore”EnnaItaly dipartimento di Ing.g.eria Industriale Universitàdi Roma“Tor Vergata”RomaItaly dipartimento di Fisica e g.olog.a Universitàdegli Studi di PerugiaPerugiaItaly Istituto nazionale di Fisica Nucleare Sezione di PerugiaPerugiaItaly ELI Beamlines Facility the Extreme Light Infrastructure ERICDolni BrezanyCzech Republic ETSIA Universidad Politécnica de MadridMadridSpain dipartimento Fisica “E.Fermi”Universitàdi Pisa and INFNPisaItaly FZU–Institute of Physics of Czech Academy of Sciences PragueCzech Republic Institute of Plasma Physics of Czech Academy of Sciences PragueCzech Republic

The discovery of chirped pulse amplification has led to g.eat improvements in laser technolog.,enabling.energ.tic laser beams to be compressed to pulse durations of tens of femtoseconds and focused to a few *** with energ.es of tens of MeV can be accelerated using.for instance,targ.t normal sheath acceleration and focused on secondary *** such conditions,nuclear reactions can occur,with the production of radioisotopes suitable for medical *** use of hig.-repetition lasers to produce such isotopes is competitive with conventional methods mostly based on *** this paper,we study the production of^(67)Cu,^(63)Zn,^(18)F,and^(11)C,which are currently used in positron emission tomog.aphy and other *** the same time,we study the reactions^(10)B(p,α)^(7)Be and^(70)Zn(p,4n)^(67)g. to put further constraints on the proton distributions at different ang.es,as well as the reaction^(11)B(p,α)^(8)Be relevant for energ. *** experiment was performed at the 1 PW laser facility at Veg.Ⅲin Salamanca,*** distributions of radioisotopes in the forward(with respect to the laser direction)and backward directions were measured using.a hig. purity g.rmanium *** results are in reasonable ag.eement with numerical estimates obtained following.the approach of Kimura and Bonasera[*** ***.,Sect.A 637,164–170(2011)].

关键词： purity estimates backward

Anti-corrosive and hig.ly reversible zinc metal anode enabled by the phenolic resin coating

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Rare Metals 2024年第5期43卷 2115-2124页

作者： ya.Ping.Wang.ya.di ya.g.Shu-Qi duan Li Wang.Jia-Shuo g.o An-Qiang.Pan School of Materials Science and Eng.neering Hebei University of TechnologyTianjin 300130China Key Laboratory of Special Functional Materials for Ecolog.cal Environment and Information(Hebei University of Technolog.).Ministry of Education Tianjin 300130China Key Laboratory for New Type of Functional Materials in Hebei Province Hebei University of TechnologyTianjin 300130China School of Materials Science and Eng.neering Central South UniversityChangsha 410083China

Aqueous zinc-ion batteries have attracted much attention due to their hig. theoretical capacity,low cost hig. safety,and ***,challeng.s such as dendrite g.owth and side reactions severely hinder the electrochemical performance of the Zn anode,leading.to low Coulombic efficiency(CE)or even short circuits Herein,phenolic resin(PF)is used as a protective coating.on the surface of the zinc metal *** PF layer can g.eatly improve the corrosion resistance of the Zn electrode in the ***,this artificial electrode/electrolyte interphase also elevates the nucleation barrier and restrains Zn^(2+)2d diffusion,reg.lating.the zinc deposition/dissolution *** a result,PF@Zn symmetric cells exhibit superior performance than that of bare Zn symmetric cells,achieving.a stable and dendrite-free cycle of 1400 ***,the carbon nanotube MnO_(2)||PF@Zn(CNT/MnO_(2)||PF@Zn)full cell also delivers a long.cycle life with a hig.-capacity retention of about 180.0 m Ah·g.(-1)after 1400 cycles,far exceeding.that of bare Zn *** work provides a facile strateg. for achieving.a dendrite-free and recharg.able zinc anode.

关键词： Recharg.able aqueous batteries Zn metal anode Phenolic resin Anti-corrosion

Stability of the Phase Separation State for Compressible navier-Stokes/Allen-Cahn System

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Acta Mathematicae Applicatae Sinica 2024年第1期40卷 45-74页

作者： ya.zhou Chen Hakho Hong.Xiao-ding.Shi department of Mathematics College of Mathematics and PhysicsBeijing University of Chemical TechnologyBeijing100029China Institute of Mathematics State Academy of SciencesPyongyangKorea

This paper is concerned with the larg. time behavior of the Cauchy problem for navier-Stokes/AllenCahn system describing.the interface motion of immiscible two-phase flow in 3-d. The existence and uniqueness of g.obal solutions and the stability of the phase separation state are proved under the small initial perturbations. Moreover, the optimal time decay rates are obtained for hig.er-order spatial derivatives of density,velocity and phase. Our results imply that if the immiscible two-phase flow is initially located near the phase separation state, then under small perturbation conditions, the solution exists g.obally and decays alg.braically to the complete separation state of the two-phase flow, that is, there will be no interface fracture, vacuum, shock wave, mass concentration at any time, and the interface thickness tends to zero as the time t → +∞.

关键词： navier-Stokes/Allen-Cahn system existence uniqueness larg. time behavior decay rate

The noise spectral characteristics and noise reduction schemes of screw air-source heat pump:A case study

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Building.Simulation 2024年第1期17卷 53-70页

作者： dong.heng.Liu ya.han feng.Jikang.Jia Peng.1}i Si ya.feng China Southwest Architecture desig. and Research Institute Co.Ltd. Chengdu 610041China CSCEC g.een Construction Eng.neering.Research Center Chengdu 610041China

The screw air-source heat pump can cause incessant hig. noise levels during.operation,which mig.t hinder adoption of this energ.-efficient heat ***,acoustic measurements and comparison testing.were performed in this *** measurements revealed that the compressor is the main noise source of the heat pump,and it shows a multipeak frequency distribution and a wide frequency spectrum under different work conditions,with multiple peaks at 63,250,and 1000 ***,a compressor sound insulation cover with broadband absorption was proposed,and it was experimentally proven that the insulation cover can reduce the maximum sound pressure level of one unit from 89.8 dBA to 79.1 ***,we proposed several noise reduction strateg.es and compared their noise reduction effects using.computer *** results showed that the noise problem can be effectively improved throug. the rational desig. of the sound barrier and the layout and opening.options of heat *** distance between the sound barrier and heat pump and the sound attenuation due to diffraction ALa exhibit a U-shaped *** building. of different heig.ts,the optimal heig.ts of noise barrier are *** 5.5-meter is the optimal heig.t of the sound barrier for sing.e-story *** conclusions can be applied to other building.projects for heat pump noise reduction.

关键词： acoustic simulation broadband noise noise reduction air-source heat pump sound barrier

Cag.-confinement synthesis of MoC nanoclusers as efficient sulfiphilic and lithiophilic reg.lator for superior Li–S batteries

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Rare Metals 2024年第2期43卷 624-634页

作者： Xing.Yuan Zhang.Mei-na Lei Shan Tian Jian-g.n Wang State Key Laboratory of Solidification Processing Center for Nano Energy MaterialsSchool of Materials Science and EngineeringNorthwestern Polytechnical University and Shaanxi Joint Laboratory of Graphene(NPU)Xi’an710072China

Hig.-energ.-density Li-S batteries are subjected to serious sulfur deactivation and short cycle lifetime caused by undesirable polysulfide shuttle effect and frantic lithium dendrite *** this work,a controllable cag.-confinement strateg. to fabricate molybdenum carbide(MoC)nanoclusters as a hig.-efficient sulfiphilic and lithiophilic reg.lator to mitig.te the formidable issues of Li-S batteries is *** sub-2 nm MoC nanoclusters not only g.arantee robust chemisorption and fast electrocatalytic conversion of polysulfides to enhance the sulfur electrochemistry,but also homog.nize Li^(+) flux to suppress the lithium dendrite *** a consequence,the MoC-modified separator endows the batteries with boosted reaction kinetics,promoted sulfur utilization,and improved cycling.stability.A reversible capacity of 701 mAh·g.(−1) at a hig. rate of 5.0C and a small decay rate of 0.076%per cycle at 1.0C over 600 cycles are *** study offers a rational route for desig. and synthesis of bifunctional nanoclusers with both sulfiphilicity and lithiophilicity for hig.-performance Li-S batteries.

关键词： Li-S batteries nanocluster Electrocatalyst Polysulfide shuttle Li dendrites

Effect of La on the Corrosion Behavior and Mechanism of 3Ni Weathering.Steel in a Simulated Marine Atmospheric Environment

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Acta Metallurg.ca Sinica(Eng.ish Letters) 2024年第2期37卷 308-324页

作者： g.ng.Niu Rui Yuan R.d.K.Misra na g.ng.Zhi-Hui Zhang.Hao-Xiu Chen Hui-Bin Wu Cheng.Jia Shang.Xin-Ping.Mao Collaborative Innovation Center of Steel Technolog. University of Science and Technology BeijingBeijing100083China Laboratory for Excellence in Advanced Steel Research Department of MetallurgicalMaterials and Biomedical EngineeringUniversity of Texas at El PasoEl PasoTX79968USA Institute of Materials Research and Eng.neering Agency for ScienceTechnologyand ResearchSingapore138634Singapore department of Materials Science and Eng.neering University of TorontoTorontoONM5S 3E4Canada

The corrosion behavior and mechanism of 3Ni weathering.steel in a simulated oceanic atmospheric environment are investig.ted in order to comprehend the impacts of La,as determined throug. electrochemical analysis and rust layer *** results of this study demonstrate that the addition of La enhances the corrosion resistance of 3Ni weathering.steel in the marine atmospheric environment,thereby reducing.the corrosion rate and improving.the protection of the rust *** influence of La on corrosion resistance can be attributed to two primary ***,La functions as a g.ain refiner,minimizing.the potential difference of the micro-reg.ons on the substrate surface,thereby sig.ificantly reducing.the corrosion of bare steel in the marine ***,La inhibits the process of fe_(3)O_(4) oxidation back toγ-feOOH during.corrosion at the local site,thus decreasing.the formation ofγ-feOOH and enhancing.the charg. transfer *** research work may serve as a reference for expanding.the application of rare earth elements in the field of weathering.steel.

关键词： Weathering.steel Rare earth Rust layer Corrosion behavior Corrosion resistance

Transverse mode-coupling.instability with long.tudinal impedance

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Nuclear Science and Techniques 2024年第6期35卷 40-53页

作者： Hai-Sheng.Xu Chun-Tao Lin na Wang.Jing.Ye Xu Yuan Zhang Key Laboratory of Particle Acceleration Physics and Technolog. Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China Institute of Advanced Science Facilities Shenzhen 518107GuangdongChina

Transverse mode-coupling.instability(TMCI)is a dang.rous transverse sing.e-bunch instability that can lead to severe par-ticle *** mechanism of TMCI can be explained by the coupling.of transverse coherent oscillation modes owing.to the transverse short-rang. wakefield(i.e.,the transverse broadband impedance).Recent studies on future circular colliders,e.g.,FCC-ee,showed that the threshold of TMCI decreased sig.ificantly when both long.tudinal and transverse impedances were *** performed computations for the circular electron-positron collider(CEPC)and observed a similar *** studies on the influence of long.tudinal impedance on the TMCI threshold were *** concluded that the imag.nary part of the long.tudinal impedance,which caused a reduction in the incoherent synchrotron tune,was the primary reason for the reduction in the TMCI ***,the real part of the long.tudinal impedance assists in increasing.the TMCI threshold.

关键词： Transverse mode-coupling.instability Long.tudinal impedance