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Naturally Nitrogen-Doped Biochar Made from End-of-Life Wood Panels for SO_(2) Gas Depollution

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Journal of Renewable Materials 2023年第11期11卷 3807-3829页

作者： Hamdi Hachicha Mamadou dia Hassine Bouafif Ahmed Koubaa Mohamed Khlif Flavia Lega Braghiroli Research Forest Institute(Institut de Recherche sur les Forets IRF)University of Quebec in Abitibi-Temiscamingue(UQAT)Rouyn-NorandaQC J9X 5E4Canada Technology Center for Industrial Waste(Centre Technologique des Residus Industriels CTRI)College of Abitibi-Temiscamingue(Cégep de L’Abitibi-Témiscamingue)Rouyn-NorandaQC J9X 5E5Canada Ecole D’ingenieur de Sfax Universite de SfaxSfax3038Tunisia

Reconstituted wood panels have several advantages in terms of ease of manufacturing,but their shorter life span results in a huge amount of reconstituted wood panels being discarded in sorting centers ***,the most common approach for dealing with this waste is *** this study,reconstituted wood panels were converted into activated biochar through a two-step thermochemical process:(i)biochar production using pilot scale fast pyrolysis at 250 kg/h and 450℃;and(ii)a physical activation at three temperatures(750℃,850℃ and 950℃)using an in-house activation furnace(1 kg/h).Results showed that the first stage removed about 66% of the nitrogen from the wood panels in the form of NO,NH3,and trimethylamine,which were detected in small amounts compared to emitted CO_(2).Compared to other types of thermochemical conversion methods(e.g.,slow pyrolysis),isocyanic acid and hydrogen cyanide were not detected in this *** second stage produced activated biochar with a specific surface area of up to 865 m^(2)/g at 950℃.The volatile gases generated during activation were predominantly composed of toluene and *** two-step process resulted in nitrogen-rich carbon in the form of pyrrolic and pyridinic *** biochars were then evaluated for their SO_(2) retention performance and showed an excellent adsorption capacity of up to 2140 mg/g compared to 65 mg/g for a commercial activated carbon(889 m^(2)/g).End-of-life reconstituted wood panels and SO_(2) gas are problematic issues in Canada where the economy largely revolves around forestry and mining industries.

关键词： End-of-life wood panels pyrolysis activation biochar and activated biochar N-doped carbons SO_(2)removal

Generation of Gata-1 Tissue-specific Knockout Mouse Model Using CRISPR/Cas9 System

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Generation of Gata-1 Tissue-specific Knockout Mouse Model Us...

作者： fatoumata binta MACI BAH 东北师范大学

学位级别：硕士

转录因子Gata1对类红细胞的发育至关重要。因此Gata1突变体胚胎由于严重的贫血而死于子宫中。通常认为除了造血系统外,Gata1只表达于组织的支持细胞中。但是我们实验室最近表述了Gata1在脂肪组织中也有表达。为了研究Gata1在脂肪组织发... 详细信息

转录因子Gata1对类红细胞的发育至关重要。因此Gata1突变体胚胎由于严重的贫血而死于子宫中。通常认为除了造血系统外,Gata1只表达于组织的支持细胞中。但是我们实验室最近表述了Gata1在脂肪组织中也有表达。为了研究Gata1在脂肪组织发育过程中的作用,我们运用CRISPR/Cas9系统构建了脂肪组织特异的Gata1敲除的小鼠模型。CRISPR/Cas9系统是一种有效的基因打靶技术并能够实现多种基因的编辑。在我们的研究中,我们分别针对人及小鼠的GATA-1基因设计了四种sg RNAs(Sg2,Sg3,Sg4,Sg5)和3种sg RNAs(Sg1,Sg2,Sg3)。我们经过细胞水平验证有效的Sg RNAs,在ap2启动子介导下形成脂肪组织特异的基因敲除小鼠。转基因小鼠之间相互交配来维持繁殖。这个仍在研究。我们发现依赖于CRISPR的基因编辑是序列特异的并且可以同时引入多个g RNAs,并实现靶位点有效的多种编辑。我们分别在小鼠和人的GATA-1基因中得到606bp和多于1kb的缺失片段。我们建立了一种容易并且多样的RNA-指导的基因编辑工具。

关键词： GATA-1转录因子 VEGF-A CRISPR/Cas9 脂肪组织肥胖

Epidemioclinical Aspects of Childhood Domestic Accidents in the Emergency Department of Boffa Hospital

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Open Journal of Pediatrics 2023年第6期13卷 947-954页

作者： Bangoura Mmah Aminata Kolié Ouo Ouo Bangoura Kaba Camara Salématou Hassimiou Diop Mamadou Moustapha Touré Oumar Deen Camara Emmanuel dia.lo fatoumata binta Bémy Pé Néabey Touré Mariame Oumar Institut de Nutrition et de Santé de l’Enfant Conakry Guinée Service de pédiatrie Hô pital national Donka Conakry Guinée Service de chirurgie pédiatrique Hô pital national Donka Conakry Guinée Hô pital préfectoral de Boffa Boffa Guinée

Introduction: Domestic accidents are defined as accidents that occur in the home or its immediate surroundings. Objective: To describe the epidemioclinical and therapeutic aspects. Patients and Methods: Prospective, descriptive study from July 1, 2019 to June 30, 2020 in the emergency department of Boffa prefectural hospital included all children aged 0 to 15 years admitted for domestic accidents. Results: Of 120 cases of accidental trauma, 56 were domestic accidents. The mean age was 7.08 years. The 0 - 5 and 11 - 15 age groups were the most represented (35.71%). The sex ratio was 1.55 in favor of boys. Domestic accidents were represented by falls (26.78%), thermal burns (21.43%), snakebite wounds (17.86%) and dog bites (10.71%), drowning (5.36%), and electrification by lightning (3.60%), one case or 1.78% of each of the following: esophageal foreign body by palm nut, firearm, wall collapse, stretching of upper limb. Paracetamol was the molecule most frequently used (89.28%). The outcome was favorable in 92.86% of cases. However, four (4) deaths were recorded. Conclusion: Domestic accidents remain a significant pathology at Boffa prefectural hospital.

关键词： Domestic Accidents Children Hospital Prefecture Boffa Guinea Conakry

Personal Experience of Chinese Medical History:On the Occasion of My Inaugural Professorial Lecture,March 2022

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Chinese Medicine and Culture 2023年第3期6卷 301-312页

作者： Vivienne lo History Department University College LondonLondon WC1E6BTthe United Kingdom

1 Introduction The Inaugural Lecture,I imagine,is meant to be a pre-sentation that demonstrates my best work or something summative about my academic career;however,unlike my colleagues who have delivered amazing mid-career lectures on topic,because I started as a very mature stu-dent after at least two previous careers,and am now two years from retirement,this presentation is surely some kind of swan song.

关键词： Medical something career

Prognosis Factors of Urinary Quality of Life in Parkinson Disease

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Open Journal of Therapy and Rehabilitation 2024年第1期12卷 10-17页

作者： Ngor Side diagne Sakhi Othman Ababacar Mamadou Gueye Marie Jeanne Sakho Fatou dialo Mboup Amélie Ndeye Makarame Sy Papa Ndiouga lo Ba Seydina Ousmane Anna Modji Basse Maouly Fall Adjaratou Dieynaba Sow Moustapha Ndiaye Amadou Gallo Diop Physical Médicine and Rehabilitation Department Fann Teaching Hospital Dakar Senegal Neurology Department Pikine Hospital Dakar Senegal Physical Médicine and Rehabilitation Department Ibn Rochd Teaching Hospital Casablanca Morocco Physical Médicine and Rehabilitation Department Military Hospital Dakar Senegal Neurology Department Fann Teaching Hospital Dakar Senegal

Introduction: Quality of life in Parkinson disease is not necessary linked to motor symptoms. It’s correlated of overactive bladders and prostatic symptoms. Prognosis factors of urinary quality of life are unknown. Objectives: Our study aims to find prognosis factors of quality of life associated specifically of urinary disorders in PD. Patients and methods: We conducted a transversal, analytic and descriptive study in Physical Medicine, and Neurology departments, Fann Teaching Hospital, Dakar and included patients followed for treatment of PD. Urinary disorders, quality of life and functional autonomy were assessed respectively by Urinary Symptoms Profile (USP), Qualiven Short Form, Schwab and England Scale. Results: 38 patients presented PD, with a mean age of 60.89 ± 13.6 years and sex-ratio of 2.45. Mean duration of PD was 3.1 ± 2.9 years. Urinary disorders were found in 47.36% and dominated by incontinence (88.88%) and overactive bladders (88.88%) which were minor in more than 55%. Quality of life was impaired in 88.88% of cases. Minor forms (43.75%) were predominant and constraint dimension (50%) was the most severely altered. Prognosis factors for quality of life of urinary disorders were PD stages (0.046) and functional autonomy (0.042). Discussion and conclusion: Urinary disorders in PD are common, impaired quality of life, especially the constraint dimension, depends on stage of evolution of PD and functional autonomy of patients.

关键词： Urinary Quality of Life Parkinson Disease Dakar

Lycium barbarum polysaccharides and ferroptosis:jumping into the era of novel regulated cell death

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Neural Regeneration Research 2022年第7期17卷 1473-1474页

作者： Amy Cheuk Yin lo Ming Yang Department of Ophthalmology Li Ka Shing Faculty of MedicineThe University of Hong KongHong Kong Special Administrative RegionChina

Lycium barbarum polysaccharides(LBP)are the key bioactive components of Lycium barbarum(also named Gouqizi or Goji berry or wolfberry),a widely used Traditional Chinese herb for more than 2000 *** to balance"yin"and"y... 详细信息

关键词： benefits consumed balance

Role of Intrahepatic Regional Immunity in Post-Transplant Cancer Recurrence

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Engineering 2022年第3期8卷 57-64页

作者： Jiang Liu Chung Mau lo Kwan Man Hepatopancreatobiliary Center Beijing Tsinghua Changgung HospitalTsinghua UniversityBeijing 102218China Department of Surgery HKU-Shenzhen Hospital&LKS Faculty of MedicineThe University of Hong KongHong Kong 999077China

Hepatic malignancy is a major indication for liver transplantation;however,post-tra ns plant cancer recurrence is an emerging clinical challenge affecting long-term ***-tra ns plant tumor biology,staging,and post-transplant immunosuppression regimens have been elucidated as risk factors for recurrent liver ***,increasing evidence indicates that hepatic ischemia and reperfusion(IR)injury to allografts are crucial to providing a favorable immunologic microenvironment for cancer cell invasiveness and metastasis after liver *** association of severe graft injury in marginal grafts,such as small-for-size or fatty grafts,with lower recurrence-free survival rates in living donor liver transplantations,substantiates the correlation between hepatic IR injury and cancer *** has been demonstrated to trigger intrahepatic immunological microenvironment remodeling,including pro-inflammatory responses exacerbating graft injury and anti-inflammatory responses promoting tissue ***,the role of regional immunity in post-transplant cancer recurrence is not comprehensively *** review describes the up-to-date evidence of the intrahepatic humoral microenvironment and regional regulatory immunological microenvironment induced by IR injury,as well as their roles in cancer recurrence after liver transplantation.A comprehensive understanding of regional immunity will provide novel precise diagnostic,therapeutic,and prognostic strategies for post-transplant cancer recurrence.

关键词： Liver transplantation Liver cancer Recurrence Immunology

Endothelial DLC1 is dispensable for liver and kidney function in mice

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Genes & Diseases 2022年第3期9卷 814-819页

作者： Ying Tan Su Hao lo Department of Biochemistry and Molecular Medicine University of California-DavisSacramentoCA 95817USA

DLC1 is a focal adhesion molecule that regulates cell polarity,proliferation,migration,and ***1 functions as a tumor suppressor and its expression is often down-regulated *** malignant neoplasms of epithelial *** studies have suggested that lack of DLC1 in endothelial cells may contribute to the development of angiosarcoma,and that DLC1 mutations have been identified in patients with nephrotic syndrome,a disease mainly due to leaky glomerular filtration *** demonstrate whether lack of endothelial DLC1 induces angiosarcoma and/or damages glomerular capillaries leading to nephrotic syndrome,we have extended our analyses on endothelial cell-specific DLC1 knockout mice with focuses on their liver and kidney *** were monitored up to 24 months of ***,no histological or clinical difference was found between DLC1 knockout and wild type mice,indicating that lack of endothelial DLC1 alone does not compromise kidney and liver function in mice.

关键词： Angiosarcoma DLC1 Focal adhesion Nephrotic syndrome Tumor suppressor

Soldiers’ Hypertension Prevalence in Military Garrisons in the City of Conakry

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Open Journal of Nephrology 2016年第4期6卷 132-137页

作者： Alpha Oumar Bah Mamadou Foinké Bah fatoumata binta Fofana Mariama Beavogui Departement of Nephrology Donka National Hospital Conakry Guinea Departement of Armies’ Health Conakry Guinea Departement of Cardiology Ignace Deen National Hospital Conakry Guinea

High blood pressure (HBP) is a public health problem worldwide. The objective of this study is to determine the prevalence of hypertension in military garrisons in Conakry, the capital. Material and Methods: The study was done in military garrisons. The data concern 1025 soldiers. This prospective and cross-sectional study took place from 13 November 2014 to 13 February 2015. Only the military who had agreed to participate in the study were included. Sociodemographic, clinical data and urine dipsticks were collected. Results: Among 1025 soldiers, 222 cases of HPB were observed, that was 21.66%. They were 193 men (86.94%) and 29 women (13.06%). The mean age was 46.05 years (range: 18 - 77 years). HPB cases were discovered in 155 soldiers (69.82%) in random observations. Following the grade of hypertension: 124 were of grade I, 62 of grade II, 35 of grade III and 1 case of isolated systolic hypertension was identified. Urinary dipstick tests showed that, 3 patients had proteinuria, 26 patients suffered from leucocyturia, 11 patients suffered from glycosuria and 1 case of hematuria was also identified. More than half of the soldiers (41%) were in the army. Officers were strongly affected (80.18%), followed by non-commissioned officers (17.12%) and finally enlisted men (2.70%). Risk factors were multiple: 78.82% ate very salty food;emotional stress;physical inactivity was observed in over half of the cases. Conclusion: This study gives an overall picture of the prevalence of hypertension in the military in Guinea. The discovery of the symptom lies on the systematic measurement of blood pressure.

关键词： High Blood Pressure Military Prevalence Conakry