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Effects of moringa oleifera aqueous extract on the growth performance,blood characteristics,and histological features of gills and livers in Nile tilapia

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Aquaculture and Fisheries 2024年第1期9卷 85-92页

作者： mahamoud A.Emam Ramy m.Shourbela Waleed N.El-Hawarry Seham Y.Abo-Kora fatma Abdel-monem Gad Ashraf m.Abd El-latif mahmoud A.O.Dawood Histology Department Faculty of Veterinary MedicineBenha UniversityBenha13511Egypt Department of Animal Husbandry and Animal Wealth Development Faculty of Veterinary MedicineAlexandria UniversityAlexandria22758Egypt Pharmacology Department Faculty of Veterinary MedicineBenha UniversityBenha13511Egypt Clinical Pathology Department Faculty of Veterinary MedicineBenha UniversityBenha13511Egypt Department of Aquatic Animal Diseases and management Faculty of Veterinary MedicineBenha UniversityBenha13511Egypt Animal Production Department Faculty of AgricultureKafrelsheikh UniversityKafr El-Sheikh33511Egypt The Center for Applied Research on the Environment and Sustainability The American University in CairoCairo11835Egypt

moringa oleifera is well known as a highly nutritious plant and a water purifier in fish *** fish has many impressive qualities making them very suitable for ***,this study aimed to evaluate the effect of supplementation of moringa oleifera aqueous extract(mOAE)at varying concentrations(0,100,200,and 400 mg/kg diet for 90 days)on growth performance,hematological,and some biochemical parameters of Nile ***,histological changes and immunohistochemical expression of caspase 3 in gills and livers were *** enhancements(Pmoglobin,packed cell volume,white blood cells,and total serum protein were observed in fish fed 200 mg mOAE/kg diet compared with other ***,a significant reduction(Pmg mOAE/kg diet revealed disturbance in the corresponding *** histological degenerative changes were detected in the gills and liver of fish fed 400 mg mOAE/kg *** comparison,fish fed 200 mg mOAE/kg diet showed the best histo-architectures of these organs compared with other *** immune expressions of caspase 3 were determined where gills and liver of fish fed 400 mg mOAE/kg diet revealed extensive number of positive caspase 3 cells indicating severe apoptotic ***,a dietary mOAE at 200 mg/kg diet is recommended to improve the growth performance,hematological parameters,liver and kidney functions in Nile ***,caution must be considered when using mOAE at a concentration over 200 mg/kg diet.

关键词： Growth performance Liver Gills moringa oleifera Nile tilapia

Risk factors and mortality rates of carbapenem-resistant Gram-negative bacterial infections in intensive care units

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Journal of Intensive medicine 2024年第3期4卷 347-354页

作者： Tulay Orhan Kuloglu Gamze Kalin Unuvar fatma Cevahir Aysegul Ulu Kilic Emine Alp Infection Control Committee Faculty of MedicineErciyes UniversityKayseriTurkey Department of Infectious Diseases Faculty of MedicineErciyes UniversityKayseriTurkey Programme of First and Emergency Aid Sakarya UniversitySakaryaTurkey Department of Infectious Diseases Faculty of MedicineYıldırım Beyazıt UniversityAnkaraTurkey

Background The prevalence of hospital-acquired infections caused by carbapenem-resistant gram-negative bacteria(CRGNB)is increasing *** risk factors have been associated with such *** present study aimed to identify risk factors and determine the mortality rates associated with CRGNB infections in intensive care *** This retrospective case-control study was conducted at Erciyes University Hospital(Kayseri,Turkey)between January 2017 and December *** and laboratory data were obtained from the Infection Control Committee data and record *** who had CRGNB infection 48–72 h after hospitalization were assigned to the case group,while those who were not infected with CRGNB during hospitalization formed the control *** factors,comorbidity,demographic data,and mortality rates were compared between the two *** Approximately 1449 patients(8.97%)were monitored during the active follow-up period;of those,1171 patients were included in this *** infection developed in 14 patients(70.00%)who had CRGNB colonization at admission;in 162(78.26%)were colonized during hospitalization,whereas 515(54.56%)were not *** was no significant difference in age,sex(male/female)or *** total length of hospital stay was statistically significantly longer(P=0.001)in the case group(median:24[interquartile range:3–378]days)than the control group(median:16[interquartile range:3–135]days).The rates of colonization at admission(25.5%;vs.10.6%,P=0.001)and mortality(64.4%vs.45.8%,P=0.001)were also significantly higher in the cases than in the control group,*** the univariate analysis,prolonged hospitalization,the time from intensive care unit admission to the development of infection,presence of CRGNB colonization at admission,transfer from other hospitals,previous antibiotic use,enteral nutrition,transfusion,hemodialysis,mechanical ventilation,tracheostomy,reintubation,central veno

关键词： multidrug resistance Gram-negative bacteria Infection Intensive care units

Epidemiological and histopathological characteristics of thyroid carcinoma in a Tunisian health care center

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第1期10卷 37-42页

作者： maissa Ben Thayer fatma Khanchel Imen Helal Dorra Chiboub Hedhli Raoueh Ehsen Ben Brahim Raja Jouini Aschraf Chadli-Debbiche Faculty of medicine of Tunis Tunis El Manar UniversityTunisTunisia Depatment of Pathology Habib Thameur's HospitalTunisTunisia Department of Otorhinolaryngology-Head and Neck surgery Habib Thameur's HospitalTunisTunisia

Background:Thyroid carcinoma(TC)accounts for almost 0.5%–1%of total *** incidence is increasing rapidly *** studies have drawn up the epidemiological profile of TC and its clinical and pathological ***,to date,no similar studies have been conducted in ***:To establish an epidemiological profile of TC in a Tunisian health care institute and to analyze its clinical and histopathological characteristics in our *** and methods:We present a retrospective study reviewing the cases of TC diagnosed in our institution in a 4-year ***:We collected a sample of 192 cases of *** consisted of 31 males and 161 females(83.8%)with a sex-ratio m/F of *** mean age was 46.4 *** thyroid carcinoma was the most frequent histological *** multifocality rate was 33.8%.The mean size of TC was 2.2±1.9 cm.60.9%of TC were staged pT1 and 20.3%had nodal *** thyroid microcarcinomas were noted in 37.5%of ***:Our results were consistent with those of the literature.A high proportion of pT1 and pN0 tumors were noted in our series,suggesting that TC's diagnosis and management was performed at an early stage of the disease in our *** addition,our study enabled us to notice the impact of the Coronavirus disease 19 crisis on the management of TC in our *** studies are needed to establish the epidemiological profile of TC in Tunisia and to assess its clinical and pathological features.

关键词： coronavirus disease 19 epidemiology papillary thyroid carcinoma papillary thyroid microcarcinoma pathology thyroid carcinoma

A New Reliable System For managing Virtual Cloud Network

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Computers, materials & Continua 2022年第12期73卷 5863-5885页

作者： Samah Alshathri fatma m.tal.at Aida A.Nasr Department of Information Technology College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh 11671Saudi Arabia Faculty of Artificial Intelligence Kafrelsheikh UniversityKafrelsheikhEgypt Faculity of Computers and Informatics Tanta UniversityTantaEgypt

Virtual cloud network(VCN)usage is popular today among large and small organizations due to its safety and ***,it makes all resources in the company work as one *** also facilitates sharing of files and applications without ***,cloud providers face many issues in managing the VCN on cloud computing including these issues:Power consumption,network failures,and data *** issues often occur due to overloaded and unbalanced load *** this paper,we propose a new automatic system to manage VCN for executing the *** new system calledmulti-User Hybrid Scheduling(mUSH)can solve running issues and save power during workflow *** consists of three phases:Initialization,virtual machine allocation,and task scheduling *** mUSH system focuses on the execution of the workflow with deadline ***,it considers the utilization of virtual *** new system can save makespan and increase the throughput of the execution operation.

关键词： Virtual network scheduling reliability Vm allocation cloud computing

Ultrafast laser dynamics of metal organic frameworks/TiO_2 nano-arrays hybrid composites for energy conversion applications

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Journal of Energy Chemistry 2019年第2期28卷 88-94页

作者： fatma m.Ismail Daniel O'Neil Tareq Youssef Souad A.Elfeky The National Institute of Laser Enhanced Sciences Cairo University Zewail City of Science and Technology Georgia Institute of Technology

Herein,we report the victorious synthesis of metal-organic frameworks(mOFs) on TiO_2 nanotubes(NTs)using a layer-by-layer(LbL) *** crystalline and homogenous thin films of mOFs were grown and characterized using XRD,SEm,FT-IR and UV/Vis ***,the utilization of the mOF films as sensitizers was probed in bespoke Graetzel type liquid junction solar *** constructed cell performance revealed an I_(sc) of 1.16 mA cm^(–2),Vocof 0.63 V,FF of 0.33,and E_(ff) of 0.42%.Further,pumpprobe transient laser spectroscopy was performed to investigate the energy and charge transfer dynamics of the mOFs/TiO_2 NTs *** results indicated 86% injection *** ultrafast pump-probe spectroscopy allows the investigation of this process and the differences between *** also showed that the relaxation of the mOF chromophores is in competition with electron injection in the Ti O2 *** this study provides a new insight into electron transfer from photoexcited metal-organic frameworks(mOFs) into titanium dioxide.

关键词： Ultrafast laser dynamics metal-organic frameworks TiO2 nano-arrays Energy conversion Thin film

microalbuminuria in hepatitis C-genotype 4:Effect of pegylated interferon and ribavirin

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World Journal of Gastroenterology 2010年第10期16卷 1226-1231页

作者： moutaz Derbala fatma m Shebl Awad Rashid Aliaa Amer Abdulbari Bener Department of Gastroenterology and Hepa-tology Hamad Medical Corporation Department of medicine Weill Cornell Medical College in Qatar Infections & Immunoepidemiology Branch Division of Cancer Epidemiology and GeneticsNational Cancer Institute Epidemiology Branch National Liver Institute Department of Nephrology Hamad Medical Corporation Department of Laboratory medicine and Histo-pathology Hematology SectionHamad Medical Corporation Department of medical Statistics and Epidemiology Hamad Medical Corporation

AIm:To study the relation between hepatitis C virus (HCV) genotype 4 and microalbuminuria and renal impairment in relation to hepatic histology, and viremia in the absence of cryoglobulinemia, and to examine the effect of treatment on ***: Three hundred subjects, including 233 HCV genotype-4 infected patients, were tested for cryoglobulinemia, microalbuminuria, albumin creatinine ratio (ACR), urea, creatinine, and estimated glomerular filtration rate (eGFR). The parameters were measured again in the HCV patients after 48 wk of treatment with pegylated interferon and ***: Significantly higher levels of microalbumin- uria were detected in HCV-positive patients compared to HCV-negative controls (median 9.5 vs 5.9, respectively, Kruskal-Wallis P=0.017). Log microalbuminuria was significantly correlated with hepatic inflammation (r=0.13, P=0.036) and f ibrosis (r=0.12, P=0.061), but not with viral load (r=-0.03, P=0.610), or alanine transaminase (r=-0.03, P=0.617). Diabetes mellitus neither significantly moderated (χ2=0.13, P=0.720), nor mediated (Sobel test P=0.49) the HCV effect. HCV status was signifi cantly associated with log microalbu-minuria (χ2=4.97, P=0.026), adjusting for age, gender, diabetes, cryoglobulinemia, urea and creatinine. A positive HCV status was not significantly associated with low eGFR (mL/min every 1.73 m2) [odds ratio (OR): 0.5, 95% confidence interval (CI):0.2-1.4], nor with high ACR (OR: 1.7, 95% CI:0.7-4.1). End-of-treatment response (ETR) was achieved in 51.9% of patients. Individuals with ETR had significantly lower microalbuminuria post-treatment (χ2=8.19, P=0.004).CONCLUSION: HCV affected the development of microalbuminuria independent of diabetes or cryoglobulinemia. Combination therapy of pegylated interferon-ribavirin had a positive effect in reducing microalbuminuria.

关键词： Hepatitis C virus Genotype Kidney diseases Albuminuria Proteinuria Peginterferon α-2a Ribavirin

Persea americana attenuates inflammatory response associated with hyperlipidemia in ovariectomized and irradiated rats by regulating mmP-3/TImP-1 levels

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Asian Pacific Journal of Tropical Biomedicine 2022年第9期12卷 374-382页

作者： Dina F.Elmaghraby fatma A.m.Salem Esraa S.A.Ahmed Department of Health Radiation Research National Center for Radiation Research and TechnologyEgyptian Atomic Energy AuthorityCairoEgypt Department of Chemistry Faculty of ScienceHelwan UniversityCairoEgypt Radiation Biology Research National Center for Radiation Research and TechnologyEgyptian Atomic Energy AuthorityCairoEgypt

Objective:To explore the effect of Persea americana supplementation on inflammation,oxidative stress,and lipid profiles in ovariectomized rats fed with a high-fat diet and exposed to ***:The control group was sham operated,while groups 2-5 were ovariectomized and fed a high-fat *** 4 and 5 were exposed toγ-radiation(1 Gy/week for 5 weeks)after *** 3 and 5 were treated with 1 mL/250 g/day of Persea americana for one *** levels of estrogen,alanine aminotransferase,aspartate aminotransferase,cholesterol,triglycerides and lipoproteins were ***,hepatic oxidative stress,inflammatory and fibrogenic markers were ***:Persea americana treatment reduced the oxidative stress markers as well as the levels of triglyceride,total cholesterol,and low-density lipoprotein cholesterol,which in turn lowered hepatic fat ***,it suppressed hepatic inflammatory mediators(interleukin-6,tumor necrosis factor-α,and C-reactive protein)and downregulated pro-fibrogenic markers(transforming growth factor-βand tissue inhibitor of metalloproteinase-1).Conclusions:Persea americana provides protection against ovariectomy,and gamma radiation-mediated hepatic inflammation not only through its antioxidant,anti-inflammatory,lipid-lowering effect but also by modulating the fibrogenic markers.

关键词： Persea americana γ-Radiation Postmenopausal Oxidative stress Lipid Ovariectomy Hepatic inflammation Fibrogenic Rat

Ginseng ameliorates pulmonary toxicity induced by silicon dioxide nanoparticles in rats

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Asian Pacific Journal of Tropical Biomedicine 2021年第6期11卷 254-262页

作者： Raghda A.El-Sayed fatma m.El-Demerdash mohammed A.El-magd Department of Environmental Studies Institute of Graduate Studies and ResearchAlexandria UniversityEgypt Department of Anatomy Faculty of Veterinary MedicineKafrelsheikh UniversityEgypt

Objective:To investigate the protective and therapeutic role of ginseng against silicon dioxide nanoparticles(SiO2NPs)-induced toxicity in the ***:Sixty male rats were divided into five groups(n=12/group);group 1 was used as a control,group 2 received ginseng,group 3 was treated with SiO2NPs,and group 4 was pretreated with ginseng one week before SiO2NPs,while group 5 was given SiO2NPs one week before supplementation with *** were treated with both ginseng and SiO2NPs orally for five ***-time PCR was used to measure gene ***,DNA damage and cell cycle changes were determined by comet assay and flow cytometry,*** study was also done to assess the effect of ginseng on SiO2NPs-induced ***:SiO2NPs increased lipid peroxidation and decreased the activities of antioxidant ***2NPs induced apoptosis in lung tissues as revealed by upregulation of Bax and caspase 3 and downregulation of Bcl-2 as well as the induction of DNA ***2NPs also caused inflammation as indicated by upregulation of the inflammation-related genes[interleukin 1 beta(IL-1β),tumor necrosis factor-alpha(TNF-α),nuclear factor kappa B(NF-κB),cyclooxygenase 2(COX2),and transforming growth factor-beta 1(TGFβ1)]as well as cell cycle arrest in the G0/G1 phase of lung ***,histopathological examination proved the biochemical and molecular perturbations that occurred due to SiO2NPs ***,ginseng alleviated SiO2NPs-induced toxicity in rat ***:Ginseng has a potent preventive and therapeutic effect and could be used in the treatment of SiO2NPs-induced pulmonary toxicity.

关键词： Silicon dioxide nanoparticles Ginseng Oxidative stress Inflammation Pulmonary toxicity

Controlled drainage in the Nile River delta of Egypt:a promising approach for decreasing drainage off-site effects and enhancing yield and water use efficiency of wheat

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Journal of Arid Land 2023年第4期15卷 460-476页

作者： mohamed K EL-GHANNAm fatma WASSAR Sabah mORSY mohamed HAFEZ Chiter m PARIHAR Kent O BURKEY Ahmed m ABDALLAH Soil Water and Environment Research InstituteAgricultural Research CenterGiza 12112Egypt Higher Institute of Water Sciences and Techniques of Gabès University of GabèsGabès 6072Tunisia Institute of Arid Regions Medenine 4119Tunisia Crop Science Department Faculty of AgricultureDamanhour UniversityDamanhour 22516Egypt Land and Water Technologies Department Arid Lands Cultivation Research InstituteCity of Scientific Research and Technological ApplicationsNew Borg El-Arab 21934Egypt Indian Council of Agricultural Research(ICAR)-Indian Agricultural Research Institute(IARI) New Delhi 110012India United States Department of Agriculture(USDA)-Agricultural Research Services(ARS) Plant Science Research UnitNorth Carolina 27607USA Natural Resources and Agricultural Engineering Department Faculty of AgricultureDamanhour UniversityDamanhour 22516Egypt

North Africa is one of the most regions impacted by water *** implementation of controlled drainage(CD)in the northern Nile River delta of Egypt is one strategy to decrease irrigation,thus alleviating the negative impact of water *** study investigated the impacts of CD at different levels on drainage outflow,water table level,nitrate loss,grain yield,and water use efficiency(WUE)of various wheat *** levels of CD,i.e.,0.4 m below the soil surface(CD-0.4)and 0.8 m below the soil surface(CD-0.8),were compared with subsurface free drainage(SFD)at 1.2 m below the soil surface(SFD-1.2).Under each drainage treatment,four wheat cultivars were grown for two growing seasons(November 2018–April 2019 and November 2019–April 2020).Compared with SFD-1.2,CD-0.4 and CD-0.8 decreased irrigation water by 42.0%and 19.9%,drainage outflow by 40.3%and 27.3%,and nitrate loss by 35.3%and 20.8%,*** CD treatments,plants absorbed a significant portion of their evapotranspiration from shallow groundwater(22.0%and 8.0%for CD-0.4 and CD-0.8,respectively).All wheat cultivars positively responded to CD treatments,and the highest grain yield and straw yield were obtained under CD-0.4 *** the initial soil salinity as a reference,the soil salinity under CD-0.4 treatment increased two-fold by the end of the second growing season without negative impacts on wheat *** the drainage system by raising the outlet elevation and considering shallow groundwater contribution to crop evapotranspiration promoted water-saving and *** responses could be obtained based on the different plant tolerance to salinity and water stress,crop characteristics,and growth ***-specific soil salinity management practices will be required to avoid soil salinization due to the adoption of long-term shallow groundwater in Egypt and other similar agroecosystems.

关键词： drainage ratio nitrate loss water use efficiency yield soil salinity Nile River delta