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Effect of acupressure on procedural pain before heel lancing in neonates

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Journal of Traditional Chinese Medicine 2021年第2期41卷 331-337页

作者： Tanju Oğul fatma Yilmaz Kurt Research Assistant RNMSNFaculty of Health SciencesPediatric Nursing DepartmentCanakkale Onsekiz Mart UniversityCanakkale 17020Turkey

OBJECTIVE:To investigate the effect of acupressure applied to UB60 and K3 acupuncture points in order to relieve the procedural pain caused by heel lancing blood sampling process in the term ***:The data were collected by using the Information Form and the Neonatal Infant Pain *** applied for 3 min before heel lancing blood sampling in the newborns in the experimental group(n=31).No intervention was applied to newborns in the control group(n=32).RESULTS:A significant difference was found between mean scores of the newborns in the control and acupressure group in favor of the acupressure group in terms of heart rate during and after the procedure,oxygen saturation before,during and after the procedure,duration of crying during and after the procedure(P<0.05).It was found that there was a significant difference between groups in terms of Neonatal Infant Pain Scale mean scores during(P=0.001)and after the procedure(P<0.05),and the difference was found to be in favor of the acupressure ***:As a result,acupressure was found to be an effective method in relieving pain caused by heel lancing blood sampling in newborns.

关键词： Acupressure Pain,procedural Infant,newborn Heel lancing blood sampling

Toxicity, inheritance and biochemistry of clofentezine resistance in Tetranychus urticae

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Insect Science 2011年第5期18卷 503-511页

作者： Recep Ay fatma Ebru Kara Suleyman Demirel University Faculty of Agriculture Department of Plant Protection Cunur Isparta Turkey

This study evaluates the toxicological and biochemical response of two-spotted spider mites to clofentezine selection pressure. The mortality rate of Tetranychus urticae in adult females depends on increased clofentezine concentration and clofentezine was found to be effective against females. The resistance rate of the CUM strain selected 12 times once per generation with clofentezine was increased from 1.28- to 105.27-fold. The interaction of some synergists with clofentezine was analyzed in the clofentezine-resistant CLOF 12 strain. Synergists had no effect on clofentezine toxicity. The clofentezine-resistant CLOF 12 strain showed resistance against chlorpyrifos, abamectin, propargite, fenpyroximate and amitraz. The modes of inheritance of resistance to clofentezine were found to be incompletely dominant and not sex-linked. Esterase enzyme activity was detected both by gel electrophoresis and microplate reader methods, while glutathione S-transferase （GST） and monooxygenase （P450） activity were detected only by the microplate reader method. During the selection period the esterase, the GST and the P450 enzymes activities were raised from 7.69, 7.09 and 0.003 3 to 18.40, 13.11 and 0.003 7 milli-optical density/rain/rag proteins, respectively. An increase was observed in the band intensity of esterases and esterase enzymes may play a role in clofentezine resistance in T. urticae.

关键词： acaricide resistance clofentezine esterase glutathione S-transferase monooxygenase Tetranychus urticae

Mechanical properties of vanadium-alloyed austempered ductile iron for crankshaft applications

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Frontiers of Mechanical Engineering 2023年第3期18卷 251-263页

作者： fatma BAYATA Süleyman Batuhan VATAN Department of Mechanical Engineering Istanbul Bilgi University34060 IstanbulTurkey

This study focused on the development of austempered ductile iron(ADI)with desirable combination of mechanical properties for crankshaft applications by the combined effect of vanadium(V)alloying and an optimized heat treatment *** produced unalloyed GGG60,0.15%V-alloyed GGG60(V-15),and 0.30%V-alloyed GGG60 samples were subjected to austenitizing at 900℃for 1 h and subsequent austempering processes at 250,300,and 350℃for 15,30,60,90,and 180 *** a result of these austempering processes,different bainitic structures were obtained,which led to the formation of diverse combinations of mechanical *** mechanical properties of the austempered samples were tested comprehensively,and the results were correlated with their microstructures and the stability of the retained austenite *** the microstructural observations,the V-alloyed samples exhibited a finer microstructure and a more acicular ferrite phase than unalloyed *** V addition delayed the coarsening of the acicular ferrite structures and considerably contributed to the improvement of the mechanical properties of ***,the X-ray diffraction results revealed that the retained austenite volume and the carbon enrichment of austenite phases in ADI samples were remarkably affected by the addition of *** increase in volume fraction of retained austenite and its carbon content provided favorable ductility and toughness to V-15,as confirmed by the elongation and impact test ***,the dual-phase ausferrite microstructure of V-15 that was austempered at 300℃for 60 min exhibited high strength with substantial ductility and toughness for crankshaft applications.

关键词： austempered ductile iron(ADI) vanadium alloying mechanical properties crankshafts retained austenite

Event-Based Semantics of UML 2.X Concurrent Sequence Diagrams for Formal Verification

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Journal of Computer Science & Technology 2022年第1期37卷 4-28页

作者： Inès Mouakher fatma Dhaou J.Christian Attiogbé Faculty of Sciences of Tunis University of Tunis El Manar1068TunisTunisia Institute of Technology University of Nantes44322NantesFrance

UML 2.X sequence diagrams(SD)are among privileged scenarios-based approaches dealing with the complexity of modeling the behaviors of some current ***,there are several issues related to the standard semantics of UML 2.X SD proposed by the Object Management Group(OMG).They mainly concern ambiguities of the interpretation of SDs,and the computation of causal relations between events which is not specifically laid ***,SD is a semi-formal language,and it does not support the verification of the modeled *** justifies the considerable number of research studies intending to define formal semantics of UML *** proposed in our previous work semantics covering the most popular combined fragments(CF)of control-flow ALT,OPT,LOOP and SEQ,allowing to model alternative,optional,iterative and sequential behaviors *** proposed semantics is based on partial order theory relations that permit the computation of the precedence relations between the events of an SD with nested *** also addressed the issue of the evaluation of the interaction constraint(guard)for guarded CFs,and the related synchronization *** this paper,we first extend our semantics,proposed in our previous work;indeed,we propose new rules for the computation of causal relations for SD with PAR and STRICT CFs(dedicated to modeling concurrent and strict behaviors respectively)as well as their ***,we propose a transformational semantics in *** modeling approach emphasizes computation of causal relations,guard handling and transformational semantics into *** transformation of UML 2.X SD into the formal method Event-B allows us to perform several kinds of verification including simulation,trace acceptance,verification of properties,and verification of refinement relation between SDs.

关键词： UML 2.X sequence diagram formal semantics nested combined fragment partial order theory Event-B

Qualitative Analysis of a Fractional Pandemic Spread Model of the Novel Coronavirus (COVID-19)

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Computers, Materials & Continua 2021年第1期66卷 843-869页

作者： Ali Yousef fatma Bozkurt Thabet Abdeljawad Department of Mathematics Kuwait College of Science and Technology27235Kuwait Department of Mathematics Erciyes UniversityKayseri38039Turkey Department of Mathematics and General Sciences Prince Sultan UniversityRiyadh11586Saudi Arabia Department of Medical Research China Medical UniversityTaichung40402Taiwan Department of Computer Science and Information Engineering Asia UniversityTaichungTaiwan

In this study,we classify the genera of COVID-19 and provide brief information about the root of the spread and the transmission from animal(natural host)to *** establish a model of fractional-order differential equations to discuss the spread of the infection from the natural host to the intermediate one,and from the intermediate one to the human *** the same time,we focus on the potential spillover of bat-borne *** consider the local stability of the co-existing critical point of the model by using the Routh–Hurwitz ***,we analyze the existence and uniqueness of the constructed initial value *** focus on the control parameters to decrease the outbreak from pandemic form to the epidemic by using both strong and weak Allee Effect at time ***,the discretization process shows that the system undergoes Neimark–Sacker Bifurcation under specific ***,we conduct a series of numerical simulations to enhance the theoretical findings.

关键词： Allee Effect coronavirus fractional-order differential equations local stability Neimark–Sacker bifurcation

Castle architecture in Anatolia： Fortifications of Diyarbakir

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Frontiers of Architectural Research 2013年第2期2卷 209-221页

作者： fatma Meral Halifeosiu Department of Architecture Dicle University Diyarbakir 21280 Turkey

The ancient wails of Diyarbakir are the city＇s most important urban etement, exhibiting an artistic grace through the arrangement of the towers, architectural values, dimensions, materiats, and decorations. Diyarbakir is located at the crossroads of important trade routes, one connecting the Western World to the Far East and the other connecting North to South. Architecturally, its defensive waits and towers make it one of the most important surviving casttes. In this study, the history, location, architectural and building properties of fortifications of Diyarbakir were explained and technical dimensioning typology studies on towers and city watts were submitted.

关键词： Diyarbakir Fortifications ofDiyarbakir Castte Citadel Tower ptans Typotosy

Differences in physiological and biochemical responses to summer drought of Pinus nigra *** and Pinus brutia in a natural mixed stand

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Journal of Forestry Research 2020年第5期31卷 1479-1487页

作者： Ayse Deligoz fatma Gokce Cankara Faculty of Forestry Isparta University of Applied Sciences32260 IspartaTurkey

Understanding how tree species respond to drought in their natural environment is needed to predict forest adaptation and management practices under global environmental *** study was carried out to determine and compare physiological and biochemical responses to variations in environmental conditions during summer drought of mixed natural stands of Pinus nigra ***(Lamb.)Holmboe and Pinus brutia *** xylem water potential(ψmd),water relations,photosynthetic pigments,total soluble sugar and proline contents were investigated during the growing season.ψmd followed a similar seasonal trend in both species but *** *** had higher ψmd than *** ψmd gradually decreased from June,reached its lowest value in August,and then increased *** decreases in the osmotic potential at turgor loss point(ψnTLP)were observed during the ***,ψnTLP was lower in *** soluble sugars decreased from April to June for ***,then increased and stayed relatively constant August to *** changes were found at lower values in *** *** accumulation and photosynthetic pigments were higher in *** results indicate that physiological and biochemical responses of both species against changing environmental conditions were in different degrees but followed similar *** *** is more sensitive to summer drought than *** in their natural environment.

关键词： Pinus nigra subsp.pallasiana Pinus brutia Osmotic potential Photosynthetic pigments Soluble sugars Proline Summer drought

Interactions of zinc and cadmium toxicity in their effects on growth and in antioxidative systems in tomato plants (Solanum lycopersicum)

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Journal of Environmental Sciences 2011年第5期23卷 837-844页

作者： Jaouhra Cherif Chamseddine Mediouni Wided Ben Ammar fatma Jemal Unit of Research "Nitrogenized Nutrition and Metabolism and Stress Proteins" UR 99/09-20 Department of BiologyFaculty of Science University of Tunis Tunis 2092 Tunisia Unit of Research "Nitrogenized Nutrition and Metabolism and Stress Proteins" UR 99/09-20 Department of BiologyFaculty of ScienceUniversity of Tunis Tunis 2092 Tunisia

The interaction between zinc and cadmium was investigated in tomato plants （Solanum lycopersicum）. Ten-day-old seedlings were treated with 10 μmol/L CdC12 associated to different concentrations of ZnC12 （10, 50, 100, and 150 μmol/L）. Zn supply clearly reduced Cd accumulation in leaves and simultaneously increased Zn concentration. Cd induced oxidative stress in leaves as indicated by an increase in thiobarbituric acid-reactive substances （TBARS） level and chlorophyll breakdown. Furthermore, compared with control, Cd- treated plants had significantly higher activities of superoxide dismutase （SOD, EC 1.***.1.1）, whereas, catalase （CAT, EC 1.***.1.6）, ascorbate peroxidase （APX, EC 1.***.1.11）, and glutathione reductase （GR, EC 1.***.4.2） activities were significantly suppressed by Cd addition. Zn supplementation, at low level, restored and enhanced the functional activity of these enzymes （SOD, CAT, APX and GR） as compared to Cd-alone-treated plants. The beneficial effect of adequate Zn level on Cd toxicity was confirmed by a significant decrease in TBARS level and restoration of chlorophyll content. However, when Zn was added at high level in combination with Cd there was an accumulation of oxidative stress, which was higher than that for Cd or excess Zn alone treatments. These results suggested that higher Zn concentrations and Cd are synergistic in their effect on plant growth parameters and oxidative stress.

关键词： Solanum lycopersicum cadmium zinc oxidative stress antagonism synergism.

Investigation of Extracts from Tunisian Ethnomedicinal Plants as Antioxidants,Cytotoxins,and Antimicrobials

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Biomedical and Environmental Sciences 2017年第11期30卷 811-824页

作者： Guesmi fatma Ben Hadj Ahmed Sami Landoulsi Ahmed Laboratory of Biochemistry and Molecular Biology Faculty of Sciences of BizerteUniversity of CarthageZarzouna 7021Tunisia Laboratory of Protein Engineering and Bioactive Molecules(LIP-MB) National Institute of Applied Sciences and Technology(INSA T)BP 6761080 Tunis CedexTunisia

Objective To determine the medicinal potential of various plants and their parts extracted with different solvents. Methods The total phenolic content of acetonitrile/water（60%-40%）（ACN/W） and aqueous（W） extract fractions was determined by high-performance liquid chromatography（HPLC）, and terpenic compounds were detected by gas chromatography/mass spectrometry（GC/MS）. Antioxidant activity of the samples was evaluated using 2,2-diphenyl-1-picrylhydrazyl（DPPH） assay and β-carotene bleaching method. Cell viability was investigated by thiazolyl blue tetrazolium bromide [3-（4,5-dimethylthiazol）-2-yl 2,5-diphenyltetrazolium bromide]（MTT） assay. The mechanisms involved in cytotoxic activity were investigated in a murine macrophage cell line（RAW 264.7） and cancer lines. Results Our findings show that 11 plant species exhibited biological activity. In addition, moderate antibacterial activity was reported against one or more of the tested bacterial strains at two concentrations： 300 μg and 3 mg/disc. Furthermore, our data reveal that among all plants investigated, some extract and hydrophobic fractions were potent scavengers of the DPPH radical（6.78 μg/m L 〈 EC50 〈 8.55 μg/mL）. Taken together, our results show that Nerium oleander（NOACN/W） and Pituranthos tortuosus（PTACN/W） were highly cytotoxic against RAW 264.7 cells with IC80 values of 0.36, and 1.55 μg/mL, respectively. In contrast, murine macrophage cell lines had low growth and were significantly sensitive to water extracts of Thymus hirtus sp. algeriensis（THW）, Lavandula multifida（LMW）, and ACN/W extract of Erica multiflora（EMACN/W） at doses 〉 400, 47.20, and 116.74 μg/m L, respectively. The current work demonstrates that RAW 264.7 cell proliferation was inhibited by samples in a dose-dependent manner. Conclusion Our findings, validated through free radical scavenging activity, agar diffusion assay, and cytotoxicity of essential oils towards cancer cells, show that ethnomedicinal plants used in this work have a novel

关键词： Phenolic compounds Cytotoxicity Antioxidant Antibacterial