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BHJO: A Novel Hybrid Metaheuristic Algorithm Combining the Beluga Whale, Honey Badger, and Jellyfish Search Optimizers for Solving Engineering Design Problems

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Computer Modeling in Engineering & Sciences 2024年第10期141卷 219-265页

作者： Farouq Zitouni Saad Harous Abdulaziz S.Almazyad Ali Wagdy mohamed Guojiang Xiong fatima Zohra Khechiba Khadidja Â Kherchouche Department of Computer Science and Information Technology Kasdi Merbah UniversityP.O.Box 30000OuarglaAlgeria Department of Computer Science College of Computing and InformaticsUniversity of SharjahP.O.Box 27272SharjahUnited Arab Emirates Department of Computer Engineering College of Computer and Information SciencesKing Saud UniversityP.O.Box 51178Riyadh11543Saudi Arabia Operations Research Department Faculty of Graduate Studies for Statistical ResearchCairo UniversityGiza12613Egypt Applied Science Research Center Applied Science Private UniversityAmman11937Jordan Guizhou Key Laboratory of Intelligent Technology in Power System College of Electrical EngineeringGuizhou UniversityGuiyang550025China

Hybridizing metaheuristic algorithms involves synergistically combining different optimization techniques to effectively address complex and challenging optimization *** approach aims to leverage the strengths of multiple algorithms,enhancing solution quality,convergence speed,and robustness,thereby offering a more versatile and efficient means of solving intricate real-world optimization *** this paper,we introduce a hybrid algorithm that amalgamates three distinct metaheuristics:the Beluga Whale Optimization(BWO),the Honey Badger Algorithm(HBA),and the Jellyfish Search(JS)*** proposed hybrid algorithm will be referred to as *** this fusion,the BHJO algorithm aims to leverage the strengths of each *** this hybridization,we thoroughly examined the exploration and exploitation capabilities of the BWO,HBA,and JS metaheuristics,as well as their ability to strike a balance between exploration and *** meticulous analysis allowed us to identify the pros and cons of each algorithm,enabling us to combine them in a novel hybrid approach that capitalizes on their respective strengths for enhanced optimization *** addition,the BHJO algorithm incorporates Opposition-Based Learning(OBL)to harness the advantages offered by this technique,leveraging its diverse exploration,accelerated convergence,and improved solution quality to enhance the overall performance and effectiveness of the hybrid ***,the performance of the BHJO algorithm was evaluated across a range of both unconstrained and constrained optimization problems,providing a comprehensive assessment of its efficacy and applicability in diverse problem ***,the BHJO algorithm was subjected to a comparative analysis with several renowned algorithms,where mean and standard deviation values were utilized as evaluation *** rigorous comparison aimed to assess the performance of the BHJOalgorithmabout its counterparts,shedd

关键词： Global optimization hybridization of metaheuristics beluga whale optimization honey badger algorithm jellyfish search optimizer chaotic maps opposition-based learning

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Hospitalizations for Osteoporosis-Related Fractures: Analysis from Eastern Saudi Arabia

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Open Journal of Orthopedics 2020年第6期10卷 117-123页

作者： Mir Sadat-Ali AbdulAziz H. Al-Shams Zainab R. Al Ghanim Khaleel I. Al Batran Yousef M. Al Jamaan Abrar S. Hashishi Faisal M. Al Anaz Abdul Raheem A. Al Talib fatima abdulmohsen mohamed The Department of Orthopaedic Surgery King Fahd Hospital of the University Imam Abdul Rahman Bin Faisal University Al Khobar KSA

Background and Objectives: Osteoporosis causes fragility fractures which increase the morbidity and mortality in the elderly. Our objective was to look at the hospital admissions due to fragility fractures and site of fractures. Methods: This is a retrospective study of a 2-year period (2017-2018), in which we evaluated all the admissions of fragility fractures at King Fahd Hospital of the University, Al Khobar, Saudi Arabia. A Fragility Fracture is a fracture which occurs in patients with low bone mass due to a fall from a standing height. The data were gathered from the Quadru Med patient care system for patients over the age of 50 years: sex, site of fracture, previous fractures, and treatment meted out. The hospitalization rate for fragility fractures was calculated by taking into consideration of all the adult admissions to the orthopaedic department. Ethical approval was obtained from the Institutional Review Board of the Hospital and the Imam Abdul Rahman Bin Faisal University, Dammam. Results: During the study period 187 patients with fragility fractures were admitted. The mean age was 68.55 ± 12.43 years;fracture femur was the most common with 136 (72.7%), tibia 15 (8%) and spine 14 (7.5%). At the time of discharge based on the T score of spine 50 were osteopenic and 45 were osteoporotic. Overall adult admission for the study period was 1410 patients and 13.26% were patients with fragility fractures. There were 3 (1.6%) deaths within the first 30 days in the hospital. Conclusions: Fracture femur was the most common fragility fracture seen in our study. Orthopaedic surgeons should be ready to treat all fragility fractures and treat osteoporosis appropriately so that a second fracture is prevented.

关键词： Fragility Fractures Saudi Arabia Osteopenia Osteoporosis

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Correlations between serum kidney injury molecule-1,cystatin C and immunosuppressants:A cross-sectional study of renal transplant patients in Bahrain

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Journal of Biomedical Research 2024年第3期38卷 269-277页

作者： Kannan Sridharan Shamik Shah Mona Al Hammad fatima Ali Mohammed Sindhan Veeramuthu Mona Abdulla Taher Mustafa mohamed Hammad Lamees Jawad Eman Farid Department of Pharmacology and Therapeutics College of Medicine and Medical SciencesArabian Gulf UniversityManamaKingdom of Bahrain Department of Nephrology Salmaniya Medical ComplexManamaKingdom of Bahrain Department of Internal Medicine College of Medicine and Medical SciencesArabian Gulf UniversityManamaKingdom of Bahrain Salmaniya Medical Complex ManamaKingdom of Bahrain Department of Laboratory Medicine Salmaniya Medical ComplexManamaKingdom of Bahrain Department of Microbiology Immunologyand Infectious DiseasesCollege of Medicine and Medical SciencesArabian Gulf UniversityManamaKingdom of Bahrain

Renal transplant patients receive several immunosuppressive drug regimens that are potentially nephrotoxic for *** creatinine is the standard for monitoring kidney function;however,cystatin C(Cys C)and kidney injury molecule-1(KIM-1)have been found to indicate kidney injury earlier than serum creatinine and provide a better reflection of kidney ***,we assessed Cys C and KIM-1 serum levels in renal transplant patients receiving mycophenolate mofetil,tacrolimus,sirolimus,everolimus,or cyclosporine to evaluate kidney *** used both the Chronic Kidney Disease Epidemiology Collaboration(CKD-EPI)2021 equation,which is based on creatinine and combined creatinine with Cys C,and the CKD-EPI 2012 equation,which is based on Cys C alone,to estimate glomerular filtration rate(GFR).Then,we assessed the association between serum KIM-1 and GFR<90 mL per minute per 1.73 *** observed significantly higher serum Cys C levels in patients with the elevated serum creatinine,compared with those with normal serum *** estimated GFRs based on creatinine were significantly higher than those based on the other equations,while a significant positive correlation was observed among all *** KIM-1 levels were negatively correlated with the estimated GFRs by the CKD-EPI Cys C and the combined creatinine with Cys C equations.A serum KIM-1 level above 0.71 ng/mL is likely to indicate GFR<90 mL per minute per 1.73 *** observed a significant correlation between serum creatinine and Cys C in our renal transplant ***,serum KIM-1 may be used to monitor renal function when using potentially nephrotoxic drugs in renal transplants.

关键词： KIM-1 cystatin C mycophenolate mofetil tacrolimus everolimus sirolimus cyclosporine

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Kostmann’s Neutropenia: A Case Report

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Open Journal of Pediatrics 2024年第5期14卷 869-872页

作者： Khaoula Achir Ilham Tadmori Mounia Lakhdar Idrissi fatima Zahra Souilmi mohamed Hbibi Moustapha Hida Pediatric Department of CHU Hassan II in Fez Fez Morocco

Kostmann syndrome, or severe congenital neutropenia, is a rare condition in children marked by a neutrophil count of less than 500/mm3. This congenital agranulocytosis, an autosomal recessive genetic disorder, is often first identified by a neonatal infectious syndrome. The deficiency in neutrophils increases susceptibility to bacterial and fungal infections. Prior to the availability of hematopoietic growth factors, the disease was associated with significant morbidity and early mortality. We present the case of a 17-month-old boy who was admitted to the pediatric emergency department at Hassan II University Hospital in Fes with skin abscesses.

关键词： Kostmann Syndrome Severe Congenital Neutropenia Skin Abscesses

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Sausage Finger Revealed a Bone Sarcoidosis

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International Journal of Dermatology and Venereology 2024年第3期7卷 176-177页

作者： fatima-Zahra Agharbi Abderrahmane Albouzidi Soumiya Chiheb Department of Dermatology Sheikh Khalifa HospitalFaculty of MedicineMohamed VI University of Health SciencesCasablanca 82403Morocco.

Dear Editor,Sarcoidosis is a systemic inflammatory disease of unknown etiology that is characterized by the forma-tion of a giganto-cellular epithelioid granuloma with-out caseous necrosis infiltrating the various *** condition most frequently involves the mediastinal and pulmonary regions,while bone involvement is rare and affects only 1.0%to 13.0%of patients with sarcoid-osis.1 We report a case of an isolated bone sarcoidosis presenting as bull’s finger.

关键词： involvement Sarcoidosis etiology

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Prostaglandin E1 administration post liver transplantation and renal outcomes:A retrospective single center experience

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World Journal of Transplantation 2024年第4期14卷 101-109页

作者： Vinay Jahagirdar mohamed Ahmed Ifrah fatima Hassam Ali Laura Alba John H Helzberg Lee S Cummings Matthew Wilkinson Jameson Forster Alisa Likhitsup Department of Internal Medicine Saint Luke’s Health System of Kansas City and the University of Missouri-Kansas CityKansas CityMO 64111United States Department of Gastroenterology and Hepatology East Carolina University Brody School of MedicineGreenvilleNC 27834United States Division of Internal Medicine Department of Gastroenterology and HepatologySaint Luke’s Health System of Kansas City and University of Missouri-Kansas CityKansas CityMO 64111United States Department of Surgery University of Missouri-Kansas City and Transplant SurgerySaint Luke’s Hospital of Kansas CityKansas CityMO 64111United States Department of Gastroenterology and Hepatology University of MichiganAnn ArborMI 48109United States

BACKGROUND Prostaglandin E1(PGE1),or alprostadil,is a potent vasodilator that improves hepatic blood flow and reduces ischemia-reperfusion injury post-liver transplantation(LT).However,the benefits of PGE1 on renal function after LT have not yet been well *** To assess the impact of PGE1 administration on renal function in patients who underwent liver or liver-kidney *** This retrospective study included all patients who underwent liver or liverkidney transplant at our institution from January,2011 to December,*** were classified based on whether they received ***1 was administered post-LT to those with transaminases>1000 U/L in the immediate postoperative ***,post-LT treatments and/or complications,renal function,and survival were *** logistic regression analysis was performed,and a two-tailed P value<0.05 was considered statistically *** A total of 145 patients underwent LT,with 44(30%)receiving *** patient characteristics were comparable,except the PGE1 group had significantly higher aspartate aminotransferase(AST)(1961.9 U/L±1862.3 U/L vs 878 U/L±741.4 U/L,P=0.000),alanine aminotransferase(1070.6 U/L±895 U/L vs 547.7 U/L±410 U/L,P=0.000),international normalized ratio on post-LT day 1(2±0.74 vs 1.8±0.4,P=0.03),a longer intensive care unit stay(8.1 days±11.8 days vs 3.8 days±4.6 days,P=0.003),more vasopressor use(55.53 hours±111 hours vs 16.33 hours±26.3 hours,P=0.002),and higher immediate postoperative complications(18.6%vs 4.9%,P=0.04).The PGE1 group also had a significantly higher 90-day readmission rate(29.6%vs 13.1%,P=0.02)and lower 1-year liver graft survival(87.5%vs 98.9%,P=0.005).However,30-day readmission(31.6%vs 27.4%,P=0.64),LT complications(hepatic artery thrombosis,biliary complications,rejection of liver graft,cardiomyopathy),1-year patient survival(96.9%vs 97.8%,P=0.77),overall liver graft survival,and overall patient survival were similar between t

关键词： Liver transplantation Alprostadil Protective agents Transplant Prostaglandin E1

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Recent advancements in the diagnosis and treatment of acral melanoma

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2024年第2期25卷 106-122页

作者： Ahmad ALHASKAWI Sohaib Hasan Abdullah EZZI Yanzhao DONG Haiying ZHOU Zewei WANG Jingtian LAI Chengjun YAO Vishnu Goutham KOTA mohamed Hasan Abdulla Hasan ABDULLA Hui LU Department of Orthopedics the First Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou310003China Department of Orthopaedics Third Xiangya HospitalCentral South UniversityChangsha410013China Zhejiang University School of Medicine Hangzhou310058China Alibaba-Zhejiang University Joint Research Center of Future Digital Healthcare Zhejiang UniversityHangzhou310058China

Acral melanoma(AM)is the most common histologic subtype of melanoma in dark-skinned patients and is associated with a worse prognosis and a high mortality rate,largely due to the inconspicuous nature of early-stage lesions,which can lead to late *** of the overlapping clinical and histopathological features of AM with other forms of cutaneous melanomas,early detection of AM requires a multidisciplinary approach that integrates various diagnostic modalities,including clinical examination,dermoscopy,histopathology,molecular testing,radiological imaging,and blood *** surgery is the preferred method of treatment for AM,other therapeutic options may be employed based on the stage and underlying etiology of the *** checkpoint inhibitors,molecular targeted therapy,radiotherapy,chemotherapy,and oncolytic virotherapy represent promising advanced treatment options for *** this review,we provide an overview of the latest advancements in diagnostic and therapeutic methods for AM,highlighting the importance of early detection and the prompt,individualized management of this challenging disease.

关键词： Acral melanoma Acral lentiginous melanoma Acral nevus Cutaneous malignant melanoma Dermoscopy Oncolytic virotherapy

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The feasibility of coating by cooling crystallization on ibuprofen naked tablets

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Frontiers of Chemical Science and Engineering 2017年第2期11卷 211-219页

作者： fatima Mameri Ouahiba Koutchoukali mohamed Bouhelassa Anne Hartwig Leila Nemdili Joachim Ulrich University Constantine 3 Engineering Faculty of Pharmaceutical Processes 25000 Constantine Algeria Martin Luther University Halle-Wittenberg Center of Engineering Science Thermal Process Engineering D-06099 Halle Germany

Sugar spray coating is a frequently used process in the pharmaceutical industry. However, this process presents the disadvantage to form an amorphous coating around the active ingredient. A crystalline coating formed on the surface of a tablet is highly desirable. Recently, a new process of coating by cooling crystallization has been developed and applied on bisacodyl pastilles obtained by melt crystallization. In this work, we investigated the feasibility of coating by cooling crystallization on ibuprofen ＂naked tablets＂ manufactured by compression. In the first part of this work, the solubility and the metastable zone width have been determined experimentally for the coating solution because they are essential factors for any crystallization process. In the second part, the coating process is investigated on the operating conditions that affect the surface morphology and the crystal growth rate. These experimental conditions include concentration of the coating solution, degree of sub-cooling, agitation speed, retention time, and surface properties of the naked ibuprofen tablets. The results show that naked tablet coating by cooling crystallization is feasible and can be applied in the pharmaceutical industry.

关键词： coating solution crystallization ibuprofen tablets sucrose

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Experimental investigation and comparative study of interturn short-circuits and unbalanced voltage supply in induction machines

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Frontiers in Energy 2013年第3期7卷 271-278页

作者： fatima BABAA Abdelmalek KHEZZAR mohamed el kamel OUMAAMAR Department of Electrical Engineering Mentouri University Constantine25000 Algeria

A transient model for an induction machine with stator winding turn faults on a single phase is derived using reference frame transformation theory. The negative sequence component and the 3rd harmonic are often considered as accurate indicators. However, small unbalance in the supply voltage and/or in the machine structure that exists in any real system engenders the same harmonics components. In this case, it is too difficult to distinguish between the current harmonics due to the supply voltage and those originated by inter-turn short- circuit faults. For that, to have the correct diagnosis and to increase the sensitivity and the reliability of the diagnostic system, it is crucial to provide the relationship between the inter-turn short-circuits in the stator winding and the supply voltage imbalance through an accurate mathematical model and via a series of experimental essays.

关键词： induction machines fault indicator inter-turn short-circuit fault unbalance supply voltage

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A hydrochemical study of the Hammam Righa geothermal waters in north-central Algeria

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Acta Geochimica 2016年第3期35卷 271-287页

作者： mohamed Belhai Yasuhiro Fujimitsu fatima Zohra Bouchareb-Haouchine Abdelhamid Haouchine Jun Nishijima Department of Earth Resources Engineering GraduateSchool of EngineeringKyushu UniversityFukuoka 819-0395Japan Department of Earth Resources Engineering Faculty ofEngineeringKyushu UniversityFukuoka 819-0395Japan Laboratoire de Geo-Environnement FSTGAT/USTHB BP 32El-Alia16000 AlgiersAlgeria

This study focuses on the hydrochemical characteristics of 47 water samples collected from thermal and cold springs that emerge from the Hammam Righa geothermal field, located in north-central Algeria. The aquifer that feeds these springs is mainly situated in the deeply fractured Jurassic limestone and dolomite of the Zaccar Mount. Measured discharge temperatures of the cold waters range from 16.0 to 26.5 ℃ and the hot waters from 32.1 to 68.2 ℃. All waters exhibited a near-neutral pH of 6.0-7.6. The thermal waters had a high total dis- solved solids （TDS） content of up to 2527 mg/l, while the TDS for cold waters was 659.0-852.0 mg/l. Chemical analyses suggest that two main types of water exist： hot waters in the upflow area of the Ca-Na-SO4 type （Ham- mam Righa） and cold waters in the recharge zone of the Ca-Na-HCO3 type （Zaccar Mount）. Reservoir tempera- tures were estimated using silica geothermometers and fluid/mineral equilibria at 78, 92, and 95℃ for HR4, HR2, and HRI, respectively. Stable isotopic analyses of the δ18O and δD composition of the waters suggest that the thermal waters of Hammam Righa are of meteoric origin. We conclude that meteoric recharge infiltrates through the fractured dolomitic limestones of the Zaccar Mount and is conductively heated at a depth of 2.1-2.2 km. The hotwaters then interact at depth with Triassic evaporites located in the hydrothermal conduit （fault）, giving rise to the Ca-Na-SO4 water type. As they ascend to the surface, the thermal waters mix with shallower Mg-rich ground- water, resulting in waters that plot in the immature water field in the Na-K-Mg diagram. The mixing trend between cold groundwaters from the recharge zone area （Zaccar Mount） and hot waters in the upflow area （Hammam Righa） is apparent via a chloride-enthalpy diagram that shows a mixing ratio of 22.6 〈 R 〈 29.2 %. We summa- rize these results with a geothermal conceptual model of the Hammam Righa geothermal field.

关键词： Thermal waters North-central Algeria Geochemistry Geothermometry Geothermal conceptualmodel Cold groundwaters

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