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Algerian mint species:high performance thin layer chromatography quantitative determination of rosmarinic acid and in vitro inhibitory effects on linoleic acid peroxidation

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Journal of Coastal Life Medicine 2014年第12期 986-992页

作者： brahmi fatiha Madani Khodir Stévigny Caroline Chibane Mohamed Duez Pierre 13BS Laboratory Faculty of Natural Sciences and LifeUniversity of BejaiaBejaia 06000Algeria Laboratory of Pharmacognosy Bromatology and Human NutritionFaculty of PharmacyFree University of BelgiumCP 205-9B-1050 BrusselsBelgium Faculty of Natural Sciences and Life and Earth Sciences Akli Mohand Oulhadj UniversityBouira 10000Algeria Laboratory of Molecular Biology Institute of Health Sciences and TechnologyUniversity of Mons(UMONS)7000 MonsBelgium

Objective:To determine the quantitative paremeters of rosmarinic acid in Algerian mints,Mentha spicata L.(***),Mentha pulegium *** Mentha rotundifolia(L.)Huds by high performance thin layer chromatography(HPTLC)-densitometric method and screen the effects of these plant extracts on linoleic acid ***:The analyses were performed on HPTLC silica gel 60 F254 plates with chloroform:acetone:formic acid(75:16.5:8.5,v/v)as the mobile *** acid was determined in UV at 365 nm and fluorescence at λ_(exc)325 nm with a 550 nm filter,*** effects of plants extracts on linoleic acid peroxidation were measured by an indirect in vitro colorimetric ***:Chromatographic resolution permitted reliable quantification in both measurement modes and calibration curves were linear in a range of 150-1000 ng/*** was found to contain significantly higher concentrations of rosmarinic *** densitometric quantification allowed the analysis of many samples in a short time with reasonable precision(total precision for Mentha spp extracts,5.1%and 5.8%for UV and fluorescence detection,respectively).The HPTLC data,allied to assays of linoleic acid peroxidation prevention,suggested the potential of ***(52%Trolox®equivalents)as a natural source for inhibitors of lipid ***:Densitometry can be used for routine determination and quality control of rosmarinic acid in herbal and formulations containing Mentha species.

关键词： Densitometry High performance thin layer chromatography Lipid peroxidation Mentha sp Rosmarinic acid

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Recent advances in the identification and the study of composition and activities of medicinal plants

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Journal of Coastal Life Medicine 2016年第12期4卷 983-999页

作者： fatiha brahmi Sabiha Achat Naima Guendouze-Bouchefa Leila Benazzouz-Smail Mahmoud Fahmi Elsebai Khodir Madani 3BS Laboratory Faculty of Natural Sciences and LifeUniversity of BejaiaBejaia 06000Algeria Department of Pharmacognosy Faculty of PharmacyMansoura UniversityMansouraEgypt

Medicinal and aromatic plants are the foremost source of life economy drugs for the majority of the world’s *** plant metabolites are essential for life as drugs,fragrances,pigments and food *** study of plants is an inevitable step in the ethnopharmacological approach and it is the reference system since it allows sitting scientifically research that follows from of these new ***,the purpose of many scientists is to advance a new approach useful for identifying plants within a folk pharmacopoeia which deserve the increased research attention of phytochemists and *** the objective to study medicinal plants,usually we start by extraction of the bioactive compounds,which is an essential ***,new important extraction processes were elaborated to recover bioactive constituants from herbal plants by augmenting the yield at inferior *** approachs and methods used in isolation and characterization of active compounds from herbal preparations are also given according to their important ***,in the present work,an update on some biological activities properties of medicinal plants is reviewed.

关键词： Medicinal plants Botanical identification Extraction Analysis methods Biological activities

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Impedance learning adaptive super-twisting control of a robotic exoskeleton for physical human-robot interaction

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IET Cyber-Systems and Robotics 2023年第1期5卷 108-121页

作者： Brahim brahmi Mohammad Habibur Rahman Maarouf Saad Department of Electrical Engineering College AhuntsicMontrealQuebecCanada Department of Mechanical Engineering University of Wisconsin-MilwaukeeMilwaukeeWIUSA Department of Electrical Engineering École de Technologie SupérieureMontrealQuebecCanada

This study addresses two issues about the interaction of the upper limb rehabilitation robot with individuals who have *** first step is to estimate the human's target position(also known as TPH).The second step is to develop a robust adaptive impedance control mechanism.A novel Non-singular Terminal Sliding Mode Control combined with an adaptive super-twisting controller is being developed to achieve this *** combination's purpose is to provide high reliability,continuous performance tracking of the system's *** proposed adaptive control strategy reduces matched dynamic uncertainty while also lowering chattering,which is the sliding mode's most glaring *** proposed TPH is coupled with adaptive impedance control with the use of a Radial Basis Function Neural Network,which allows a robotic exoskeleton to simply track the desired impedance *** validate the approach in real-time,an exoskeleton robot was deployed in controlled experimental circumstances.A comparison study has been set up to show how the adaptive impedance approach proposed is better than other traditional controllers.

关键词： adaptive control impedance model robust control super twisting controller upper limb rehabilitation robot

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Experimental performance analysis of an installed microgrid-based PV/battery/EV grid-connected system

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Clean Energy 2022年第4期6卷 599-618页

作者： Aziz Haffaf fatiha Lakdja Djaffar Ould Abdeslam Electro-Technical Department Electro-Technical Engineering LaboratoryFaculty of TechnologyTahar Moulay UniversitySaida20000Algeria IRIMAS Laboratory Haute Alsace UniversityMulhouse68093France

Global energy demand,which is largely based on fossil fuels,is expected to increase *** effort must be made to mitigate carbon emissions and climate change to ensure sustainable and clean *** recent years,the increasing share of renewable energy and energy-storage systems,the development of electric vehicles(EVs),promotion of energy efficiency and demand-side management(DSM)have become today’s solution *** microgrid(MG),which involves the interconnection of several generation and storage units capable of operating locally with or without connection to the power grid,is also a very useful emerging *** study allowed the experimental operation and performance analysis of a grid-connected photovoltaic(PV)/battery/EV MG hybrid system,which was used for maximizing PV self-consumption and DSM *** entire MG consisting of two subsystems(polycrystalline PV array of 2.16 kWp for Subsystem 1,monocrystalline PV system of 2.4 kWp for Subsystem 2,EV with lithium-ion battery capacity of 6.1 kWh)was installed under outdoor conditions at the University Institute of Technology in Mulhouse,France in August *** operation and behaviour of the system components,including the inverter,batteries and power grid,were analysed in both scenarios with and without EV *** results shows that the total cumulative energy injected into the grid during the entire system operating cycle is estimated to be 3466.82 and 5836.58 kWh for Subsystems 1 and 2,respect*** addition,the energy produced by Subsystem 2 during its lifetime and the emissions emitted are respectively estimated at 5597.65 kWh and 4.17 *** other results in terms of PV output power,energy yield,feed-in power and self-consumed energy were quantified and analysed in detail.

关键词： microgrid photovoltaic electric vehicle(EV) self-consumption demand-side management(DSM) energy management

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POLYPHENOLS, CYTOTOXICITY AND ENZYMATIC ACTIVITIES OF THREE ERIACEAE SPECIES FROM ALGERIA

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World Journal of Traditional Chinese Medicine 2015年第4期1卷 90-90页

作者： Guendouze-Bouchefa Nama brahmi fatiha Madani Khodir Chibane Mohamed Kiendrebeogo Martin Stévigny Caroline Duez Pierre Laboratoire de Biomathématique Biochimie Biophysique et Scientometrie Faculté des Sciences de la Nature et de la Vie Université de Bejaia Laboratoire de Biochimie et Chimie Appliquées(LABIOCA) Université de Ouagadougou Laboratoire de Pharmacognosie Bromatologie et Nutrition Humaine Faculte de Pharmacie Université Libre de Bruxelles (ULB) Laboratoire de Chimie Thérapeutique et de Pharmacognosie Faculté de Médecine et de PharmacieUniversité de Mons (UMONS)

In Algerian traditional medicine,Erica arborea(EA),Erica multiflora(EM)and Arbutus unedo(AU)are reported as antiseptic,diuretic,astringent,depurative,and to treat scalds and *** methanolic extracts of their leaves and aerial parts were screened for enzyme inhibitory and cytotoxic *** and HPLC chromatographic profiles based on flavonoids allowed to easily distinguish between the three investigated ***

关键词： CYTOTOXICITY AND ENZYMATIC ACTIVITIES OF THREE ERIACEAE SPECIES FROM ALGERIA POLYPHENOLS EM

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Investigations on the Optimization of Contacts Barrier Height for the Improved Performance of ZnO/CdS/CZTS Solar Cells

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Energy Engineering 2023年第8期120卷 1803-1815页

作者： fatiha Daoudi Abdelkrim Naas Omar Meglali Radia Boudaira Ahmed Gueddim A.M.Saeed Material Science and Informatics Laboratory University of DjelfaDjelfa17000Algeria Faculty of Sciences University of M’silaM’sila28000Algeria Department of Physics University of ConstantineConstantine25000Algeria Department of Physics Division of Science and TechnologyUniversity of EducationLahorePakistan

The numerical simulations were performed using the AMPS-1D simulator to study the effects of the CZTS as an absorber layer and the contacts’barrier height on the performance of four ZnO/CdS/CZTS solar *** obtain the best cell performances,the barrier heights of the back and front contacts were adjusted between 0.01,0.77,0.5,and 1.55 eV,*** simulations,we used the lifetime mode,and the device performances were evaluated under AM1.5 illumination *** found that the efficiency,fill factor,and open-circuit voltage were almost constant at a front contact barrier height of less than 0.31 *** short-current density was not affected by the front contact barrier *** back contact material had a significant impact on the CZTS cells *** best performance was obtained for the CZTS550 cell with JSC=29.53 mA/cm2,VOC=1.07 V,FF=0.88,andη=28.08%at barrier heights of 0.31 and 1.55 eV for front and back contacts,*** conduction band offset at the CZTS550/CdS hetero-junction was found to be spike-like with 0.21 *** obtained conversion efficiency is comparable to those previously reported in the literature.

关键词： CZTS solar cell barrier height AMPS-1D photovoltaic parameters

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Small ruminant value chain in Al-Ruwaished District,Jordan

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Regional Sustainability 2023年第4期4卷 416-424页

作者： Rula AWAD Hosam TITI Aziza MOHAMED-brahmi Mohamed JAOUAD Aziza GASMI-BOUBAKER Department of Animal Production National Agronomic Institute of TunisiaCarthage UniversityTunis1082Tunisia Department of Animal Production Faculty of Agriculturethe University of JordanAmman999045Jordan Higher School of Agriculture of Kef Laboratory for the Sustainability of Production Systems in the North-West RegionUniversity of JendoubaKef7119Tunisia Institute of Arid Regions Médenine Laboratory of Economy and Rural SocietiesMédenine4119Tunisia

This study aims to assess the small ruminant value chain in Al-Ruwaished District,Jordan,to identify the potential intervention areas that could improve the production efficiency and guarantee the sustainability of the small ruminant sector in this *** breeding is the source of livelihood for most of the people in Al-Ruwaished District,which is characterized by the large number of sheep and *** surveyed 5.0% of the small ruminant holders in the study area and conducted individual interviews and surveys with the potential actors in the value chain to undertake a small ruminant value chain *** the survey,we found that the small ruminant value chain consists of five core functions,namely,input supply,production management,marketing,processing,and *** the stable impression given by the large number of holdings in the small ruminant sector,the surveyed results show a clear fragility in the value chain of small ruminants in this *** small ruminant production system is negatively impacted by climate change,especially continuous *** addition,the high prices of feed that the farmer cannot afford with clear and real absence of the governmental and non-governmental support activities also impact the development of the value *** results of strengths,weaknesses,opportunities,and threats(SWOT)analysis reveal that the major constraints faced by this value chain could be divided into external and internal ***,the most prominent external threats are the nature of the desert land and continuous drought,while the major internal threats are the absence of appropriate infrastructure,shortage of inputs,and weakness in the production management and *** proposed solutions to these challenges to ensure the sustainability and effectiveness of the sector,such as the formulation of emergency response plans to severe weather,qualifying farmers’skills,and establishment of agricultural cooperative societies.

关键词： Value chain analysis Small ruminants Strengths,weaknesses,opportunities,and threats(SWOT)analysis Climate change Livestock production management Jordan

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Adaptive high-order sliding mode control based on quasi-time delay estimation for uncertain robot manipulator

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Control Theory and Technology 2020年第3期18卷 279-292页

作者： Brahim brahmi Mark DRISCOLL Mohamed Hamza LARAKl Abdelkrim brahmi Department of Mechanical Engineering Musculoskeletal Biomechanics Research Lab McGill UniversityMontrealCanada Department of Electrical Engineering University of QuebecMontrealCanada

This paper presents the design,and validation of a new adaptive control system based on quasi-time delay estimation(Q-TDE)augmented with new integral second-order terminal sliding mode control(ISOTSMC)for a manipulator robot with unknown dynamicuncertainty and *** to the conventional[TDE,the proposed Q-TDE becomes sufficient to invoke a fixed artficial time delay and utilize the past data only of the control input to approximate the unknown system's dynamic *** incorporating of new adaptive reachinglaw with ISOTSMCaugmented with Q-TDE policy ensures the continuous performance tracking of the robot manipulator's trajectories using output *** combination may achieve high performance with a significant chattering reducing *** utilizing the Lyapunov function theory,it can be demonstrated that the robot system is stable and all signals in closed-loop are converging in finite ***,Simulation and comparative studies with two degrees of freedom robot manipulator were carried out to validate the effectiveness of the designed control scheme.

关键词： Second-order sliding mode quasi-time delay estimation(Q-TDE) adaptive reaching law

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PHENOLIC PROFILE, ANTIBACTERIAL,NEUROPROTECTIVE AND CYTOTOXIC PROPERTIES OF THREE ALGERIAN MENTHA SPECIES

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World Journal of Traditional Chinese Medicine 2015年第4期1卷 87-87页

作者： brahmi fatiha Guendouze Naima Madani Khodir PhillipeN.Okusa Martin Kiendrebeogo Kamagaju Léocadie Stévigny Caroline Chibane Mohamed Duez Pierre Laboratoire de Biomathématique Biochimie Biophysique et Scientom6trie Université de Bejaia Laboratoire de Pharmacognosie Bromatologie et Nutrition Humaine Université Libre de Bruxelles (ULB) Laboratoire de Biochimie et Chimie Appliquées (LABIOCA) UFR/SVT Université de Ouagadougou Faculté des Sciences de la Nature et de la Vie et Sciences de la Terre Université Akli Mohand Oulhadj Service de Chimie Thérapeutique et de Pharmacognosie Faculté de Medecine et de Pharmacie Université de Mons(UMONS)

This study was designed to evaluate the antibacterial(direct effect and reversal of antibiotics-resistance),neuroprotective(acetylcholinesterase and carboxylesterase inhibition)and cytotoxic(MTT assay on 2 human cancer cell lines)properties of three Mentha species[*** L.(MP),***(L.)Huds(MR),and *** L.(MS)]harvested in Bejaia(Algeria).The phenolic

关键词： MR MS PHENOLIC PROFILE ANTIBACTERIAL,NEUROPROTECTIVE AND CYTOTOXIC PROPERTIES OF THREE ALGERIAN MENTHA SPECIES

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Sirtuins and nonalcoholic fatty liver disease

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World Journal of Gastroenterology 2016年第46期22卷 10084-10092页

作者： fatiha Nassir Jamal A Ibdah Research Service Harry S Truman Memorial VA Hospital University of Missouri Department of Medicine Division of Gastroenterology and Hepatology University of Missouri

Mammalian sirtuins are seven members belonging to the silent information regulator 2 family, a group of Class Ⅲ histone/protein deacetylases. Sirtuins(SIRT 1-7) have different subcellular localization and function and they regulate cellular protein function through various posttranslational modifications. SIRT1 and 3, the most studied sirtuins, use the product of cellular metabolism nicotinamide adenine dinucleotide as a cofactor to post-translationally deacetylate cellular proteins and consequently link the metabolic status of the cell to protein function. Sirtuins have been shown to play a key role in the development and rescue of various metabolic diseases including non-alcoholic fatty liver disease(NAFLD). NAFLD is currently the most chronic liver disease due mainly to high-calorie consumption and lower physical activity. No pharmacological approach is available to treat NAFLD, the current recommended treatment are lifestyle modification such as weight loss through calorie restriction and exercise. Recent studies have shown downregulation of sirtuins in human as well as animal models of NAFLD indicating an important role of sirtuins in the dynamic pathophysiology of NAFLD. In this review, we highlight the recent knowledge on sirtuins, their role in NAFLD and their unique potential role as novel therapeutic target for NAFLD treatment.

关键词： SIRT1 SIRT3 Sirtuins 非酒精的脂肪肝疾病

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