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Reducing Labor Anxiety with Auriculotherapy:A Randomized Clinical Trial Study

Chinese Journal of Integrative Medicine 2022年第5期28卷 440-444页

作者： Katayon Vakilian Mehrnoush Ghaemmaghami Narges Sheikhganbari Fatemeh Shabani Masoomeh Vahedi Department of Midwifery School of MedicineTraditional and Complementary Medicine Research CenterArak University of Medical SciencesArak(***)Iran Medical School Arak University of Medical SciencesArak(***)Iran Nursing-Midwifery School Iran University of Medical SciencesTehran(***)Iran

Objectives:To investigate the effect of auriculotherapy on reducing labor anxiety.Methods:In this randomized clinical trial,166 nulliparous pregnant women admitted to the Labor Ward of Izadi Hospital in Qom,Iran were included and assigned to two groups by randomized block design.In the intervention group(83 cases),auriculotherapy in"Shenmen,Thalamic,Zero,Brain,and Brain stem"was performed in dilatations of 4,6 and 8 cm,between the contractions for 30 s in both ears at interval 1 h.While the control group received routine care.The Spielberger Inventory were completed pre-and post-interventions.Results:The auriculotherapy was effective to reduce anxiety state in the intervention group compared to the control group(P=0.001).The score of state anxiety in the intervention group reduced for 7.0,8.0 and 11.0 U in 4,6,and 8 cm dilatations after the intervention.The score of trait anxiety in the intervention group reduced for 3.8,4.0 and 8.3 U in 4,6,and 8 cm dilatations after the intervention.There was no significant difference of delivery mode and newborns’weight and Apgar score between groups(P>0.05).No adverse postpartum outcome such as hemorrhage has been observed in both groups.Conclusion:Since most women are anxious during labor,it seems that auriculotherapy can be an easy and safe method to reduce labor anxiety.(Trial registration No.irct20121230011944 n4)

关键词： auriculotherapy childbirth pain anxiety

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Relationship between CD14-159C/T gene polymorphism and acute brucellosis risk

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Asian Pacific Journal of Tropical Medicine 2016年第3期9卷 241-245页

作者： Mehdi Moghadampour Ebrahim Eskandari-Nasab Fatemeh Shabani Department of Microbiology School of MedicineZahedan University of Medical Sciences Infectious Diseases and Tropical Medicine Research Center.Zahedan University of Medical Sciences Department of Clinical Biochemistry School of Medicine.Zahedan University of Medical Sciences Genetic of Non-Communicable Disease Research Center Zahedan University of Medical Sciences School of Medicine Jiroft University of Medical Sciences

Objective:To investigate the association between the cluster of differentiation 14(CD14)-I59C/T(rs2569190) gene polymorphism and susceptibility to acute brucellosis in an Iranian population.Methods:The study included 153 Iranian patients with active brucellosis and 128 healthy individuals as the control group.Genotyping of the CD 14 variant was performed using an amplification refractory mutation system-polymerase chain reaction method.Results:The prevalence of CD14-159 TT and CT genotypes were associated with increased risk of brucellosis[odds ratio(OR)=l.993.95%confidence interval(95%CD=1.07-3.71.P=0.03 for CT:OR=3.869.95%CI= 1.91-7.84,P=0.01 for TT genotype.Additionally,the minor allele(T) was significantly more frequently present in brucellosis patients than in controls(61%vs.45%.respectively),and was a risk factor for brucellosis(OR=3.058.95%CI= 1.507-6.315.P=0.01).Condusions:The findings provid suggestive evidence of association of the CDI4-159C/T gene polymorphism with susceptibility to acute brucellosis in the Iranian population.

关键词： Acute brucellosis Cluster of differentiation 14 Single nucleotide polymorphism

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