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Oligodendroglial heterogeneity in health,disease,and recovery:deeper insights into myelin dynamics

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Neural Regeneration Research 2025年第11期20卷 3179-3192页

作者： Pieter-jan Serneels Julie D.De Schutter Lies De Groef Lieve Moons Steven Bergmans KU Leuven Leuven Brain InstituteDepartment of BiologyAnimal Physiology and Neurobiology DivisionNeural Circuit Development&Regeneration Research GroupLeuvenBelgium KU Leuven Leuven Brain InstituteDepartment of BiologyAnimal Physiology and Neurobiology DivisionCellular Communication&Neurodegeneration Research GroupLeuvenBelgium

Decades of research asserted that the oligodendroglial lineage comprises two cell types:oligodendrocyte precursor cells and ***,recent studies employing single-cell RNA sequencing techniques have uncovered novel cell states,prompting a revision of the existing *** forward,the oligodendroglial lineage should be delineated into five distinct cell states:oligodendrocyte precursor cells,committed oligodendrocyte precursor cells,newly formed oligodendrocytes,myelin-forming oligodendrocytes,and mature *** new classification system enables a deeper understanding of the oligodendroglia in both physiological and pathological *** this uniform terminology will facilitate comparison and integration of data across ***,including the consolidation of findings from various demyelinating models,is essential to better understand the pathogenesis of demyelinating ***,comparing injury models across species with varying regenerative capacities can provide insights that may lead to new therapeutic strategies to overcome remyelination ***,by standardizing terminology and synthesizing data from diverse studies across different animal models,we can enhance our understanding of myelin pathology in central nervous system disorders such as multiple sclerosis,Alzheimer's disease,and amyotrophic lateral sclerosis,all of which involve oligodendroglial and myelin dysfunction.

关键词： animal models demyelination fish mammals multiple sclerosis myelin neurodegeneration oligodendrocytes oligodendroglial lineage remyelination

Fractional-calculus analysis of human immunodeficiency virus and CD4+T-cells with control interventions

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Communications in Theoretical Physics 2022年第10期74卷 1-15页

作者： Rashid jan Salah Boulaaras Syed Azhar ali Shah Department of Mathematics University of SwabiSwabi 23430KPKPakistan Department of Mathematics College of Sciences and ArtsArRassQassim UniversitySaudi Arabia

It is undeniable that HIV infection has been a censorious public health concern over the past four *** is reported that HIV is the main reason for AIDs which has decimated the global population of humans and imposed a significant economic burden on affected ***,it is significant to study the transmission of HIV viruses in the body of a human *** this study,we use a fractional framework to organise the intricate interactions of CD4^(+)T-cells and HIV viruses in order to investigate HIV infection with control *** apply the operators of Caputo and Atangana–Baleanu to interrogate the transmission phenomena of HIV *** the analysis of our system,we present the basic concepts of the fractional *** schemes are provided to show the solution pathways of the system with the variation of input ***,the findings emphasise the chaotic and dynamical behaviour of *** run several simulations to visualise the influence of input factors and quantitatively illustrated the dynamics of *** and oscillatory behaviour are intimately linked,and this is owing to the system’s ***,our findings indicate the most important factors for infection control and prevention.

关键词： fractional-calculus HIV infection dynamics of HIV numerical method time series analysis

A novel extended Portuguese of Interactive and Multi-Criteria Decision Making and Archimedean Bonferroni mean operators based on prospect theory to select green supplier with complex q-rung orthopair fuzzy information

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CAAI Transactions on Intelligence Technology 2023年第1期8卷 177-191页

作者： Zeeshan ali Tahir Mahmood Jeonghwan Gwak Naeem jan Department of Mathematics&Statistics International Islamic University IslamabadIslamabadPakistan Department of Software Korea National University of TransportationChungjuKorea Department of Biomedical Engineering Korea National University of TransportationChungjuKorea Department of AI Robotics Engineering Korea National University of TransportationChungjuKorea Department of IT&Energy Convergence(BK21 FOUR) Korea National University of TransportationChungjuKorea

The word sustainable or green supply chain refers to the concept of incorporating sustainable environmental procedures into the traditional supply *** supply chain management gives a chance to revise procedures,materials and operational *** the fuzziness of assessing data and the spiritual situations of experts in the decision-making procedure are two important *** main contribution of this analysis is to derive the theory of Archimedean Bonferroni mean operator for complex qrung orthopair fuzzy(CQROF)information,called the CQROF Archimedean Bonferroni mean and CQROF weighted Archimedean Bonferroni mean operators which are very valuable,dominant and classical type of aggregation operators used for examining the interrelationship among the finite number of attributes in modern data fusion *** and well-used properties of the initiated theories are also diagnosed with some special ***,the theory of extended TODIM tool using the prospect theory based on CQROF information was discovered,which play an essential and critical role in the environment of fuzzy set ***,a real life problem by computing a green supply chain management based on the initiated CQROF operators was evaluated and fully illustrating the feasibility and efficiency of the diagnosed work with the help of a comparison between existing and prevailing theories.

关键词： fuzzy set fuzzy sets

Thermal degradation of diethanolamine at stripper condition for CO2 capture: Product types and reaction mechanisms

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Chinese Journal of Chemical Engineering 2019年第12期27卷 2900-2908页

作者： Idris Mohamed Saeed Brahim Si ali Badrul Mohamed jan Wan Jefrey Basirun Shaukat ali Mazari Ibrahim ali Obid Birima Department of Chemistry Faculty of ScienceUniversity of MalayaKuala Lumpur 50603Malaysia Department of Chemical Engineering Faculty of EngineeringUniversity of MalayaKuala Lumpur 50603Malaysia Department of Chemical Engineering Faculty of EngineeringDawood University of Engineering and TechnologyMA Jinnah RoadKarachi 74800Pakistan

Amine-based absorption/stripping is one of the promising technology for CO2 capture from natural and industrial gas *** the process,amines and CO2 undergo irreversible reactions to produce undesired compounds,which cause corrosion,foaming,increased viscosity and breakdown of equipment,ultimately contributing to the economic loss and environmental *** this study,the thermal degradation of aqueous diethanolamine in the presence and absence of dissolved CO2 was *** experiments were performed in stainless steel *** results show that thermal degradation in the absence of CO2 was a slow process;triethanolamine,and tris(2-aminoethyl)amine were only the degradation products identified in the mixture In addition,the rate of degradation was very low,only 3%degradation was observed after 4 *** in the presence of CO2,sixteen degradation products were identified,nine of which were new degradation products reported for the first time in this *** 3-(2-hydroxyethyl)-2-oxazolidinone,1,4-bis(2-hydroxyethyl)piperazine and triethanolamine were the most abundant degradation *** remaining DEA concentration after 4 weeks was about 20%of the total amine *** most probable degradation reactions and their mechanisms are also proposed.

关键词： Diethanolamine CO2 capture Degradation Mechanism

Mechanistic insights toward identification and interaction of plant parasitic nematodes:A review

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Soil Ecology Letters 2024年第1期6卷 11-27页

作者： Bisma jan ali Haider Shah Mudasir Ahmad Bhat Arif Tasleem jan Ishfaq Ahmad Wani ali Asghar Shah Section of Microbiology Baba Ghulam Shah Badshah UniversityRajouriJ&K185234India Department of Biotechnology Baba Ghulam Shah Badshah University RajouriJ&K185234India Department of Botany Baba Ghulam Shah Badshah University RajouriJ&K185234India Department of Zoology School of Biosciences and BiotechnologyBaba Ghulam Shah Badshah University RajouriJ&K185234India

Nematode identification serves as an important param-eter to study their behaviour,importance and *** of classical morphometric based identifica-tion methods prove to be lacking due to insufficient knowledge on morphological variations among closely related *** approaches such as DNA and protein-based information,microarray,probing,sequence-based methods and others have been used to supplement morphology-based methods for nematode *** and certain protein-based nematode-associated molecular patterns(NAMPs),can be perceived by the host plants,and can initiate a signalling *** review primarily emphasizes on an updated account of different classical and modern tools used for the identification of *** we also summa-rize the mechanism of some important signalling pathways which are involved in the different plant nematode *** constitute most diverse and least studied group of soil inhabiting *** are ecologically and physiologically important,however,wide range of nematodes show harmful impact on the individuals that live within their *** parasitic nematodes(PPNs)are transparent,pseudocoelomate,free living or parasitic *** lack morphometric identification methods due to insufficient knowl-edge on morphological variations among closely related *** such,molecular approaches such as DNA and protein-based information,microarray,probing,sequence-based methods and others have been used to supplement morphology-based methods for their *** invade the defense response of different plant species,parasitic nematodes have evolved different molecular *** and certain protein-based nematode-associated molecular patterns(NAMPs),can be perceived by the host plants,and can initiate a signaling *** overcome the host confrontation and develop certain nematode feeding sites,some members can inject effectors into

关键词： nematode identification plant nematode interaction DNA fingerprinting nematode-associated molecular patterns signaling path-ways

Modeling the dynamical behavior of the interaction of T-cells and human immunodeficiency virus with saturated incidence

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Communications in Theoretical Physics 2024年第3期76卷 1-14页

作者： Salah Boulaaras Rashid jan Amin Khan ali Allahem Imtiaz Ahmad Salma Bahramand Department of Mathematics College of ScienceQassim UniversityBuraydah51452Saudi Arabia Institute of Energy Infrastructure(IEI) Department of Civil EngineeringCollege of EngineeringUniversiti Tenaga Nasional(UNITEN)Putrajaya CampusJalan IKRAM-UNITEN43000 KajangSelangorMalaysia Department of Mathematics University of SwabiSwabi 23561Pakistan Department of Mathematics College of SciencesQassim UniversitySaudi Arabia Institute of Informatics and Computing in Energy(IICE) Universiti Tenaga NasionalKajangSelangorMalaysia Department of Political Science Bacha Khan University CharsaddaCharsadda 24420KPK Pakistan

In the last forty years,the rise of HIV has undoubtedly become a major concern in the field of public health,imposing significant economic burdens on affected ***,it becomes imperative to undertake comprehensive investigations into the mechanisms governing the dissemination of HIV within the human *** this work,we have devised a mathematical model that elucidates the intricate interplay between CD4^(+)T-cells and viruses of HIV,employing the principles of fractional *** production rate of CD4^(+)T-cells,like other immune cells depends on certain factors such as age,health status,and the presence of infections or ***,we incorporate a variable source term in the dynamics of HIV infection with a saturated incidence rate to enhance the precision of our *** introduce the fundamental concepts of fractional operators as a means of scrutinizing the proposed HIV *** facilitate a deeper understanding of our system,we present an iterative scheme that elucidates the trajectories of the solution pathways of the *** show the time series analysis of our model through numerical findings to conceptualize and understand the key factors of the *** addition to this,we present the phase portrait and the oscillatory behavior of the system with the variation of different input *** information can be utilized to predict the long-term behavior of the system,including whether it will converge to a steady state or exhibit periodic or chaotic oscillations.

关键词： HIV infection fractional-calculus dynamics of HIV iterative scheme dynamical behaviour mathematical model fractional derivatives

Parity-check and G-matrix based intelligent early stopping criterion for belief propagation decoder for polar codes

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Digital Communications and Networks 2023年第5期9卷 1148-1156页

作者： Qasim jan Shahid Hussain Zhiwen Pan Nan Liu Zakir ali Zechen Liu Xiaohu You National Mobile Communications Research Laboratory Southeast UniversityNanjingJiangsu210096China Purple Mountain Laboratories NanjingJiangsu211100China Department of Computer Science COMSATS University IslamabadAttock CampusAttock43600Pakistan School of Medicine Computer Science and EngineeringUniversity of GalwayH91 TK33GalwayIreland Department of Computer Sciences Bahria University Lahore Campus54600Pakistan

The error correction performance of Belief Propagation(BP)decoding for polar codes is satisfactory compared with the Successive Cancellation(SC)***,it has to complete a fixed number of iterations,which results in high computational *** necessitates an intelligent identification of successful BP decoding for early termination of the decoding process to avoid unnecessary iterations and minimize the computational complexity of BP *** paper proposes a hybrid technique that combines the“paritycheck”with the“G-matrix”to reduce the computational complexity of BP decoder for polar *** proposed hybrid technique takes advantage of the parity-check to intelligently identify the valid codeword at an early stage and terminate the BP decoding process,which minimizes the overhead of the G-matrix and reduces the computational complexity of BP *** explore a detailed mechanism incorporating the parity bits as outer code and prove that the proposed hybrid technique minimizes the computational complexity while preserving the BP error correction ***,mathematical formulation for the proposed hybrid technique that minimizes the computation cost of the G-matrix is *** performance of the proposed hybrid technique is validated by comparing it with the state-of-the-art early stopping criteria for BP *** results show that the proposed hybrid technique reduces the iterations by about 90%of BP decoding in a high Signal-to-Noise Ratio(SNR)(i.e.,3.5~4 dB),and approaches the error correction performance of G-matrix and conventional BP decoder for polar codes.

关键词： Belief propagation Early termination G-matrix Parity-check Polar codes

The Hizeh-jan Kaolin Deposit of NW Iran:the Tetrad Effect in REE Distribution Patterns

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Acta Geologica Sinica(English Edition) 2019年第1期93卷 74-87页

作者： ABEDINI ali REZAEI AZIZI Mansour Department of Geology Faculty of Sciences Urmia University

The Hizeh-jan kaolin deposit(northwest of Varzeghan, East-Azarbaidjan Province, NW Iran) is a product of the alteration of Eocene andesitic rocks. Based on mineralogical examinations, kaolinite, quartz, smectite, pyrophyllite, muscovite-illite, alunite, calcite, diaspore, goethite and hematite are the most abundant mineral phases in this deposit. The geochemical indicators, such as Y/Ho and Zr/Hf, indicate the non-CHARAC(non-Charge-radius control) behavior of these pairs, which are likely to be due to the occurrence of the tetrad effect phenomenon in this deposit. Simultaneous concave and convex shapes in the chondrite-normalized REE distribution patterns are a remarkable feature of the kaolin samples. Bivariate diagrams of the size of the third tetrad effect(T_3) versus geochemical parameters such as Y/Ho, Nb/Ta and Zr/Hf ratios display two distinct populations for the kaolin samples. The first population is characterized by high T_3 values(>0.13), which are near or on the fault zone. The second population is characterized by low T_3 values(jan kaolin deposit.

关键词： REE distribution Tetrad effect Kaolin Hizeh-jan NW Iran

Retroperitoneal laparoscopic nondismembered pyeloplasty for uretero-pelvic junction obstruction due to crossing vessels: A matched-paired analysis and review of literature

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Asian Journal of Urology 2018年第3期5卷 172-181页

作者： Jens Rassweiler jan Klein ali Serdar Goezen Department of Urology and Pediatric Urology SLK Kliniken HeilbronnUniversity of HeidelbergHeibronnGermany Department of Urology Medical School UlmUniversity of UlmUlmGermany

Objective:To compare laparoscopic Anderson-Hynes pyeloplasty(LAHP)and retroperitoneal laparoscopic YV-pyeloplasty(LRYVP)in ureteropelvic junction obstruction(UPJ)in presence of a crossing vessels(CV).Methods:Our database showed 380 UPJO-cases,who underwent laparoscopic retroperitoneal surgery during the last 2 decades including 206 non-dismembered LRYVP,157 dismembered pyeloplasties LAHP,and 17 cases of laparoscopic *** them 198 cases were suitable for a matched-pair(2:1)analysis comparing laparoscopic retroperitoneal non-dismembered LRYVP(Group 1,n Z 131)and dismembered LAHP(Group 2,n Z 67)in presence of a crossing *** were matched according to age,gender,kidney functions,and obstruction *** were graded according to modified ***:Comparative data were similar between both groups(LRYVP ***)including mean operating time(112 min vs.114 min),complication rates(4.2%vs.7.3%)mainly Grade 1e2 according to Clavien classification,and success rates(90%vs.89%).These results reflected in the reviewed literature indicate that LRYVP provides the advantage of minimal dissection in case of CV with similar ***,redundant pelvis and anteriorly crossing vessels still require a dismembered pyeloplasty ***:LRYVP has achieved similar results compared with the previous golden standard of open surgery,especially in case of crossing vessels apart from presence of a redundant pelvis or anteriorly crossing *** can be further improved when using the small access retroperitoneoscopic technique respectively mini-laparoscopy.

关键词： Kidney pelvis Laparoscopy Ureteropelvic junction obstruction Mini-laparoscopy Crossing vessel