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Antiacanthamoebic properties of natural and marketed honey in Pakistan

Asian Pacific Journal of Tropical Biomedicine 2016年第11期6卷 967-972页

作者： farzana Abubakar yousuf Malik Hassan Mehmood Abdul Malik Ruqaiyyah Siddiqui Naveed Ahmed Khan Department of Biological and Biomedical Sciences Aga Khan University Department of Biological Sciences Faculty of Science and Technology Sunway University

Objective: To determine antiacanthamoebic activity of natural and marketed honey ***: Natural honey samples were collected directly from the bee hive and marketed honey samples were purchased from the local market in Karachi, Pakistan. Both honey samples were tested for their flavonoid content(quercetin equivalent per gram of the extract) and phenolic content(gallic acid equivalent per gram). Furthermore, their antioxidant activity was determined by measuring 2,2-diphenyl-1-picrylhydrazyl. Using amoebistatic and amoebicidal assays, the effects of honey samples were tested against growth and viability of Acanthamoeba ***: Natural honey exhibited potent amoebistatic and amoebicidal effects, in a concentration-dependent manner. Honey-treated Acanthamoeba castellanii showed loss of acanthopodia, following which amoebae detached, rounded up, reduced in size,decreased in cytoplasmic mass and they were observed floating in the culture ***, honey-treated amoebae did not revive when inoculated in fresh growth medium, however, glycerol-treated amoebae exhibited viable trophozoite and active growth. In contrast, marketed honey samples varied in their efficacy against Acanthamoeba castellanii. The proportion of flavonoid, as determined by quercetin measurements and the proportion of phenolic, as determined by gallic acid measurements was higher in natural honey compared with marketed honey. Similarly, the antioxidant activity, as determined by 2,2-diphenyl-1-picrylhydrazyl scavenging activity was higher in natural honey vs. marketed ***: This study shows that natural honey has antiacanthamoebic properties and possesses higher flavonoid, phenolic and antioxidant properties compared with the marketed honey. These findings are of concern to the public, health officials, and to the manufacturers regarding production of honey for medical applications.

关键词： Honey Acanthamoeba Amoebicidal Amoebistatic

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Physicochemical parameters and seasonal variation of coastal water from Balochistan coast,Pakistan

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Journal of Coastal Life Medicine 2015年第3期3卷 199-203页

作者： Naeema Elahi Quratulan Ahmed Levent Bat farzana yousuf Department of Zoology University of KarachiKarachi75270 Pakistan The Marine Reference Collection and Resources Centre University of KarachiKarachi75270 Pakistan Fisheries Faculty Department of HydrobiologySinop University57000 SinopTurkey

Objective:To determine common physico-chemical parameters of coastal ***:Physicochemical properties of water were determined according to the standards of the American Public Health ***,all those parameters were recorded a small variation between *** variation in physico-chemical parameters like salinity,temperature,dissolved oxygen and pH at Gwadar(Coastal water of Balochistan)were ***:The range of air temperature of coastal water of Balochistan during 2004 and 2006 varies from 25℃to 37℃,water temperature ranged from 15.00℃to 33.00℃,pH ranged from 7.08 to 8.95,salinity ranged from 37.4‰to 41.3‰and dissolved oxygen ranged from 5.32 to 8.67 mg/***:Results showed that these parameters of Balochistan coast of Pakistan is not dangerous for marine habitat and the use of these parameters in monitoring programs to assess ecosystem health has the potential to inform the general public and decision-makers about the state of the coastal *** save this vital important habitat,the government agencies and scientists should work with proper attention.

关键词： Physicochemical parameters Balochistan coast Pakistan

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Facile synthesis of graphene anchored rare earth doped mixed metal ferrite nanorods:A potential candidate for azo dye mineralization

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Journal of Rare Earths 2024年第5期42卷 907-916,I0004页

作者： Tehmina Kousar Muhammad Aadil Sonia Zulfiqar Sobhy MIbrahim Sidra Mubeen Warda Hassan Kashuf Shafiq farzana Mahmood Institute of Chemical Sciences Bahauddin Zakariya UniversityMultan60800Pakistan Department of Chemistry Rahim Yar Khan CampusThe Islarnia University of BahawalpurRahim Yar Khan64200Pakistan Department of Chemistry Faculty of ScienceUniversity of Ostrava30.Dubna 22Ostrava70103Czech Republic Department of Chemical and Biological Engineering Iowa State UniversitySweeney Hall618 Bissell RoadAmeslowa50011United States Department of Biochemistry College of ScienceKing Saud UniversityPO.Box 2455Riyadh11451Saudi Arabi Department of Chemistry The Women University Multan66000Pakistan

Bandgap tuning using rare earth metals as dopants in ferrite-based photocatalytic materials has received a lot of interest because the Fermi 4f energy of these metals generates a sub-energy state in the bandgap generated by the overlapping of Fe-3d and O-2p ***,dysprosium-doped cobalt-nickel mixed ferrite(D-CNFO)and its graphene-reinforced composite(D-CNFO@G)were prepared and an ideal photocatalyst material for azo dye mineralization was proposed.A cost-effective combination of wetchemical and ultrasonication methods was used to prepare the doped and composite *** characterization methodologies were used to scrutinize the optical,compositional,structural,morphological,and photocatalytic characteristics of as-prepared *** X-ray diffraction analysis identified the spinel phase's(cubic)structure,while the electronic spectroscopy examination confirmed the prepared samples'rod-like *** UV/visible absorbance spectrum shows the higher light harvesting behavior of the D-CNFO@G in the visible *** mineralization performance of the DCNFO and D-CNFO@G composites was analyzed using Congo-red(an anionic dye),a well-known azo *** D-CNFO@G sample removes Congo-red dye at a rate almost 2.4%faster than the D-CNFO *** experiment involving trapping free radicals indicates that hydroxyl radical play s a crucial role in dye *** the D-CNFO@G catalyst is magnetic and can be isolated easily from the photocatalytic system,it shows an awkward cycle activity of more than 96%after five mineralization *** asprepared D-CNFO@G composite is proved as an excellent option for azo dye mineralization because of the combined impacts of rare earth doping,graphene reinforcement and nanotechnology.

关键词： azo-dye Composite Graphene Dy-doped Nanotechnology Rare earths

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Diets of Halfbeak Hemiramphus lutkei(Valenciennes,1847)from Karachi Coast,Pakistan

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Journal of Coastal Life Medicine 2014年第2期2卷 85-88页

作者： Sadaf Tabassum farzana yousuf Naeema Elahi Md.Mosaddequr Rahman Md.Yeamin Hossain Department of Zoology University of KarachiKarachiPakistan Faculty of Fisheries Kagoshima UniversityKagoshima 890-0056Japan Department of Fisheries Faculty of AgricultureUniversity of RajshahiRajshahi 6205Bangladesh

Objective: To investigate the diets of the Lutke’s halfbeak, Hemiramphus lutkei (H. lutkei) to determine the food and feeding habits. Methods:Samples of H. lutkei were collected from the landing sites of Karachi Coast, Pakistan. Total length was measured to the nearest 0.01 cm using digital slide calipers, and total body weight was measured using an electronic balance with 0.01 g accuracy. The dietary composition was determined from gut content examination and analysis was done using frequency of occurrence and numerical methods. To assess the changes in diet with size, H. lutkei were divided into two size groups, Group 1:14-20 cm (n=250) and Group 2:21-25 cm (n=160). Results:The total length and body weight of the sampled specimens ranged from 14 to 25 cm and 10 to 23.5 g, respectively. Out of the studied specimens, 45.12%fish stomachs were found to be empty. Dietary composition revealed daphnia, small fish, isopods, unidentified animal materials, ostracods and unidentified plant materials in the gut contents of Lutke’s halfbeak. Therefore, H. lutkei is omnivore fish feeding on algae, zooplankton, small fishes and different food items of both plant and animal origin. According to the Schoener overlap index (C), there was no significant difference in feeding of the two length groups of H. lutkei (C=0.833). On the other hand, the Shannon-Wiener index showed that the prey diversity of the Lutke's halfbeak in Group 1 was lower (H'=1.545) than that of Group 2 (H'=1.653). Conclusions:This study reports the first description of diets for H. lutkei, which would be useful for the sustainable management of this fishery in the coast of Pakistan and also neighboring countries.

关键词： Food Feeding habit Hemiramphus lutkei Omnivore Pakistan

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Diet and feeding ecology of black-barred halfbeak Hemiramphus far(Forsskal, 1775) (Hemiramphidae) from Karachi coast of Pakistan

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Journal of Coastal Life Medicine 2017年第1期5卷 4-6页

作者： Sadaf Tabassum farzana yousuf Naeema Elahi MdYeamin Hossain MdAlomgir Hossen Fairuz Nawer Dalia Khatun MostFaridaParvin Department of Zoology Federal Urdu University of ArtsScience and TechnologyGulshan-e-Iqbal CampusKarachi75300Pakistan Department of Zoology University of KarachiKarachi75270Pakistan Department of Fisheries Faculty of AgricultureUniversity of RajshahiRajshahi6205Bangladesh

Objective:To describe the diet and feeding ecology ofHemiramphus far (H. far) through investigating the stomach contents. Methods: Sampling of total 430 individuals ofH. far was carried out from commercial catches landed at West Wharf fish harbor of Karachi coast, Pakistan during January–December 2010. The total length and weight of each individual were recorded. Samples were parted into Group 1 (15–20 cm,n = 240) and Group 2 (21–26 cm,n = 190), to estimate changes in diet with fish size. To remove alimentary canal, fishes were dissected and kept into 10% formalin. Then gut contents were examined under a light microscope for each intestine. Stomach fullness as well as dietary composition was ascertained from gut contents. Examination and analyses were conducted using frequency of occurrence and numerical method. Results:The examination confirmed 47.67% stomach as empty. Furthermore, our study revealed that the diet ofH. far consists of fishes, isopods, ostracods,Daphnia, shells, algae, unidentified plants and animal materials. This study proved thatH. far is an omnivorous fish feeding on fishes, isopods, shells, algae and plant and animal originated different food items. According to the Schoener overlap index, there was no significant difference in feeding of the two length groups ofH. far (C = 0.833). In addition, the Shannon-Wiener index presented that in Group 1, the prey diversity of the halfbeak was lower (H = 0.90) than that of Group 2 (H = 1.02). Conclusions: The findings of the present study would be very effective for sustainable management of black-barred halfbeak fishery in the Karachi coast of Pakistan and the surrounding ecosystems.

关键词： Pakistan Karachi coast Feeding ecology Stomach contents Hemiramphus far

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Post Thyroidectomy Assessment of Intact Parathyroid Hormone for Early Prediction of Hypocalcaemia

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International Journal of Otolaryngology and Head & Neck Surgery 2024年第2期13卷 71-84页

作者： Md. Masum Billah Ripon Kumar Sarkar Md. yousuf Ali Saad Zaman Md. Nazmul Hasan Md. Shehab Uddin Md. Mosleh Uddin Kazi Shameemus Salam farzana Binte Abedin Leera Department of Otolaryngology-Head & Neck Surgery Universal Medical College Hospital Dhaka Bangladesh Department of Otolaryngology-Head & Neck Surgery National Institute of Ear Nose and Throat Dhaka Bangladesh Shaheed Ahsan Ullah Master General Hospital Gazipur Bangladesh Department of Otolaryngology-Head & Neck Surgery Cumilla Medical College Cumilla Bangladesh Department of ENT Oncology National Institute of Cancer Research & Hospital Dhaka Bangladesh Department of ENT Outdoor Rajshahi Medical College Hospital Rajshahi Bangladesh Department of Otolaryngology-Head & Neck Surgery Bangabandhu Sheikh Mujib Medical University Dhaka Bangladesh Department of Biochemistry Delta Medical College Hospital Dhaka Bangladesh

Background: As the half-life of intact parathyroid hormone (iPTH) is very low, it reflects parathyroid insufficiency within minutes to hours after total thyroidectomy. Therefore, iPTH level assessment in the postoperative period can be used to predict the development of hypocalcaemia. The optimal time point to measure serum iPTH is important for the accurate prediction of hypocalcaemia. Aim: This paper aims to evaluate the ability of iPTH as an early predictive marker of hypocalcaemia and determine which time iPTH is more able to predict postoperative hypocalcaemia. Method: This prospective observational study was conducted in the Department of Otolaryngology-Head & Neck Surgery, BSMMU, Dhaka, from July 2020 to December 2021, with 67 patients who underwent total thyroidectomy. iPTH levels were measured on the day before the operation and at 1 hour, 4 hours, and 24 hours after the operation. *** levels were measured on the day before the operation and 1st postoperative day. All the data were compiled and sorted properly and were analyzed statistically. Results: Postoperative hypocalcaemia developed in 18 cases, with an incidence of 26.9%. Pearson correlation showed a significant correlation between postoperative iPTH at 1 hr, 4 h, and 24 hr with 1st postoperative calcium value. The Receiver operating characteristic (ROC) curve was processed for the postoperative iPTH at 1 hr, 4 h, and 24 hr. The sensitivity, specificity, cut-off value, and mean AUC found 93.9%, 94.4%, ≤14.0, 0.988;95.9%, 94.4%, ≤09.5, 0.993 and 91.8%, 94.4%, ≤11.0, 0.993 respectively. Conclusion: iPTH can be used as an early predictor of post-thy-roidectomy hypocalcaemia. 4 hr iPTH showed more sensitivity and specificity for a cut-off value near the laboratory reference range.

关键词： Total Thyroidectomy Hypocalcaemia Serum Intact Parathyroid Hormone Early Predictor of Hypocalcaemia

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Klippel Trenaunay Syndrome with Angiokeratoma Circumscriptum Naeviforme and Bilateral Congenital Anorchia: A Rare Association

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Open Journal of Pediatrics 2024年第1期14卷 43-49页

作者： Mujammel Haque Kalyan Benjamin Gomes Sajib Kumar Talukdhar Mustafizur Rahman farzana Sharmin Manik Kumar Talukder Department of Paediatrics Bangabandhu Sheikh Mujib Medical University Dhaka Bangladesh

Klippel-Trenaunay syndrome (KTS) is not a common congenital vascular abnormality. A trio of capillary malformation, venous varicosities, and bony or soft-tissue hypertrophy define this syndrome. Significant morbidities associated with this illness include bleeding, deep vein thrombosis, and embolic consequences. Angiokeratoma circumscriptum naeviforme (ACN) is indeed a congenital variant of angiokeratoma that appears as a hyperkeratotic plaque on the lower extremity. Bilateral congenital anorchia (BCA) is the total lack of testicular tissue in a male with a normal phenotype and karyotype. KTS has been linked to ACN. Here we presented an 8-year-old male child who came with a swollen left thigh and the right side of his face with overlying blackish nodules on his left thigh and scrotum. The patient was diagnosed as KTS with angiokeratoma circumscriptum naeviforme and bilateral congenital anorchia based on his history, imaging studies and the typical clinical features of the disease.

关键词： Klippel-Trenaunay Syndrome Angiokeratoma Circumscriptum Neviforme Bilateral Congenital Anorchia

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Comparison of Propofol and Fentanyl for Preventing Emergence Agitation Following Sevoflurane Anesthesia in Pediatric Patients: A Single-Center Study in Bangladesh

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Pharmacology & Pharmacy 2024年第6期15卷 223-235页

作者： Md. Saiful Islam Khan Md. Abir Tazim Chowdhury farzana Fardousi Munama Magdum Md. Ahaduzzaman Taneem Mohammad Shamima Akter Suriya Akter Md. Saiful Islam Azad Md. Mozaffer Hossain M. Abdur Rahman Department of Cardiothoracic Anesthesia Evercare Hospital Dhaka Bangladesh Department of Cardiothoracic and Vascular Surgery Evercare Hospital Dhaka Bangladesh Department of Pathology National Institute of Cancer Research & Hospital Dhaka Bangladesh Department of Preventive and Social Medicine National Institute of Preventive and Social Medicine Dhaka Bangladesh Department of Anesthesia Sheikh Sayera Khatun Medical College Gopalgonj Bangladesh Department of Anesthesia Dhaka Medical College Dhaka Bangladesh Department of Anesthesia Combined Military Hospital Dhaka Bangladesh Department of Cardiac Anesthesia National Institute of Cardiovascular Disease Dhaka Bangladesh Department of Anesthesia Bangladesh Medical College Dhaka Bangladesh

Background: Emergence agitation (EA) is a common phenomenon observed in pediatric patients following general anesthesia. This study aimed to assess the efficacy of propofol and fentanyl in preventing EA and to compare their associated complications or side effects. Methods: This prospective randomized observational comparative study was conducted at Dhaka Medical College Hospital from July 2013 to June 2014. The study aimed to evaluate the effects of propofol and fentanyl on EA in children aged 18 to 72 months undergoing circumcision, herniotomy, and polypectomy operations. Ninety children were included in the study, with 45 in each group. Patients with psychological or neurological disorders were excluded. Various parameters including age, sex, weight, American Society of Anesthesiologists (ASA) class, duration of anesthesia, Saturation of Peripheral Oxygen (SPO2), heart rate (HR), respiratory rate (RR), Pediatric Anesthesia Emergence Delirium (PAED) score, duration of post-anesthesia care unit (PACU) stay, incidence of laryngospasm, nausea, vomiting, and rescue drug requirement were compared between the two groups. Results: Age, sex, weight, ASA class, and duration of anesthesia were comparable between the two groups. Perioperative SpO2 and HR were similar in both groups. However, the PAED score was significantly higher in the fentanyl group during all follow-ups except at 30 minutes postoperatively. The mean duration of PACU stay was significantly longer in the fentanyl group. Although the incidence of laryngospasm was higher in the fentanyl group, it was not statistically significant. Conversely, nausea or vomiting was significantly higher in the fentanyl group. The requirement for rescue drugs was significantly higher in the fentanyl group compared to the propofol group. Conclusion: Both propofol and fentanyl were effective in preventing emergence agitation in pediatric patients undergoing various surgical procedures under sevoflurane anesthesia. However, propo

关键词： Emergence Agitation (EA) General Anesthesia Propofol Fentanyl Pediatric Patients Pediatric Anesthesia Emergence Delirium (PAED) Score Bangladesh

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A Process Oriented Integration Model for Smart Health Services

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Intelligent Automation & Soft Computing 2023年第2期35卷 1369-1386页

作者： farzana Kausar Gondal Syed Khuram Shahzad Muhammad Arfan Jaffar Muhammad Waseem Iqbal Department of Computer Science Superior UniversityLahore54600Pakistan Department of Informatics and Systems University of Management and TechnologyLahore54000Pakistan Faculty of Computer Science&IT Superior UniversityLahore54600Pakistan Department of Software Engineering Superior UniversityLahore54600Pakistan

Cities are facing challenges of high rise in population number and con-sequently need to be equipped with latest smart services to provide luxuries of life to its *** integrated solutions are also a need to deal with the social and environmental challenges,caused by increasing ***,the development of smart services’integrated network,within a city,is facing the bar-riers including;less efﬁcient collection and sharing of data,along with inadequate collaboration of software and *** to resolve these issues,this paper recommended a solution for a synchronous functionality in the smart services’integration process through modeling *** this integration modeling solution,atﬁrst,the service participants,processes and tasks of smart services are identiﬁed and then standard illustrations are developed for the better understand-ing of the integrated service group *** process modeling and notation(BPMN)language based models are developed and discussed for a devised case study,to test and experiment i.e.,for remote healthcare from a smart *** research is concluded with the integration process model application for the required data sharing among different service *** outcomes of the modeling are better understanding and attaining maximum automation that can be referenced and replicated.

关键词： Process modeling business process business process integration business process modeling and notation

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A Stacked Ensemble Deep Learning Approach for Imbalanced Multi-Class Water Quality Index Prediction

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Computers, Materials & Continua 2023年第8期76卷 1361-1384页

作者： Wen Yee Wong Khairunnisa Hasikin Anis Salwa Mohd Khairuddin Sarah Abdul Razak Hanee farzana Hizaddin Mohd Istajib Mokhtar Muhammad Mokhzaini Azizan Department of Biomedical Engineering Faculty of EngineeringUniversity of MalayaKuala Lumpur50603Malaysia Department of Electrical Engineering Faculty of EngineeringUniversity of MalayaKuala Lumpur50603Malaysia Institute of Biological Sciences Faculty of ScienceUniversity of MalayaKuala Lumpur50603Malaysia Department of Chemical Engineering Faculty of EngineeringUniversity of MalayaKuala Lumpur50603Malaysia Department of Science and Technology Studies Faculty of ScienceUniversity of MalayaKuala Lumpur50603Malaysia Department of Electrical and Electronic Engineering Faculty of Engineering and Built EnvironmentUniversiti Sains Islam MalaysiaNilaiNegeri Sembilan71800Malaysia

A common difficulty in building prediction models with real-world environmental datasets is the skewed distribution of *** are significantly more samples for day-to-day classes,while rare events such as polluted classes are ***,the limited availability of minority outcomes lowers the classifier’s overall *** study assesses the capability of machine learning(ML)algorithms in tackling imbalanced water quality data based on the metrics of precision,recall,and F1 *** intends to balance the misled accuracy towards the majority of ***,10 ML algorithms of its performance are *** classifiers included are AdaBoost,SupportVector Machine,Linear Discriminant Analysis,k-Nearest Neighbors,Naive Bayes,Decision Trees,Random Forest,Extra Trees,Bagging,and the Multilayer *** study also uses the Easy Ensemble Classifier,Balanced Bagging,andRUSBoost algorithm to evaluatemulti-class imbalanced learning *** comparison results revealed that a highaccuracy machine learning model is not always good in recall and *** paper’s stacked ensemble deep learning(SE-DL)generalization model effectively classifies the water quality index(WQI)based on 23 input *** proposed algorithm achieved a remarkable average of 95.69%,94.96%,92.92%,and 93.88%for accuracy,precision,recall,and F1 score,*** addition,the proposed model is compared against two state-of-the-art classifiers,the XGBoost(eXtreme Gradient Boosting)and Light Gradient Boosting Machine,where performance metrics of balanced accuracy and g-mean are *** experimental setup concluded XGBoost with a higher balanced accuracy and ***,the SE-DL model has a better and more balanced performance in the F1 *** SE-DL model aligns with the goal of this study to ensure the balance between accuracy and completeness for each water quality *** proposed algorithm is also capable of higher efficiency at a lower computa

关键词： Water quality classification imbalanced data SMOTE stacked ensemble deep learning sensitivity analysis

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