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Biological evaluation of some important medicinal plants from Poonch valley, Azad Kashmir, Pakistan

Journal of Traditional Chinese Medicine 2019年第6期39卷 753-763页

作者： farmeen kiran Muhammad Azam Khan Riffat Batool Sobia Kanwal Syed Lal Shah Tariq Mahmood Department of Plant Sciences Quaid-i-Azam University IslamabadIslamabad 45320Pakistan Department of Botany Government Boys Degree College HajiraHajira 12160Pakistan Department of Zoology University of Gujrat Sub-Campus RawalpindiRawalpindi 46000Pakistan Pakistan Museum of National History Pakistan Science FoundationIslamabadIslamabad 44000Pakistan

OBJECTIVE:To estimate the phytochemical composition,antioxidant,antifungal,cytotoxic and phytotoxic activities of three important medicinal plants of Poonch valley,Azad Kashmir ***:Phytochemicals were investigated for both qualitative(phenols,flavonoids,alkaloids and saponins)and quantitative(total phenolic and flavonoid contents)analysis of plant extracts prepared in ethanol,ethyl acetate and ***,antioxidant potential was investigated by screening botanical extracts against 2,2-diphenyl-1-picrylhydrazyl scavenging assay,phosphomolybdenum and total reducing power ***,disc diffusion method was used for determination of antifungal potential of all extracts against four pathogenic ***,brine shrimp cytotoxicity assay was conducted for cytotoxic potential and radish seed germination assay was carried out for estimation of allelopathic potential of plant ***:Phytochemical evaluation showed the presence of phenolics,flavonoids,alkaloids and saponins in almost all *** addition to significant antioxidant potential,Rubia cordifolia(ethanolic extract)revealed highest amount of phenolics and *** said plant also exhibited good cytotoxic *** plant extracts highest antifungal activity and allelopathic potential was recorded by Oxalis latifolia(ethyl acetate extract).Ethanol and ethyl acetate were observed to be the best choice of *** best solvents-based results were obtained by Ethanol followed by Ethyl acetate and ***:For further studies,Rubia cordifolia and Oxalis latifolia are the most promising medicinal plants of Poonch valley,Azad Kashmir Pakistan at molecular level in order to isolate the compounds concerning with pronounced activities.

关键词： Melinis repens Oxalidaceae Rubia Cytotoxins Pakistan

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