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Chemical composition and antioxidant activity of certain Morus species

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2010年第12期11卷 973-980页

作者： Mohammad IMRAN Hamayun khan Mohibullah SHAH Rasool khan faridullah khan Institute of Chemical Sciences University of Peshawar Department of Chemistry Islamia College University Pakistan Council of Scientific & Industrial Research (PCSIR) Laboratories Complex

In the present work,the fruits of four Morus species,namely Morus alba (white mulberry),Morus nigra (black mulberry),Morus laevigata (large white fruit),and Morus laevigata (large black fruit),were analyzed for proximate composition,essential minerals,and antioxidant *** this purpose,the ripe fruits were collected from the northern regions of *** major nutritional components moisture,ash,lipids,proteins,fibres,carbohydrates,and total sugar) were found to be in the suitable range along with good computed *** dry weight,pH,and titratable acidity (percent citric acid) were (17.60±1.94)–(21.97±2.34) mg/100 g,(3.20±0.07)–(4.78±0.15),and (0.84±0.40)%–(2.00±0.08)%,*** riboflavin (vitamin B2) and niacin (vitamin B3) contents were recorded in all the fruits,while ascorbic acid (vitamin C) was in the range from (15.20±1.25) to (17.03±1.71) mg/100 g fresh weight (FW).The mulberry fruits were rich with regard to the total phenol and alkaloid contents,having values of (880±7.20)–(1650±12.25) mg/100 g FW and (390±3.22)–(660±5.25) mg/100 g FW,*** quantities of essential macro-(K,Ca,Mg,and Na) and micro-(Fe,Zn,and Ni) elements were found in all the fruits.K was the predominant element with concentration ranging from (1270±9.36) to (1731±11.50) mg/100 g,while Ca,Na,and Mg contents were (440±3.21)–(576±7.37),(260±3.86)–(280±3.50),and (240±3.51)–(360±4.20) mg/100 g,*** decreasing order of micro-minerals was Fe>Zn>*** radical scavenging activity of methanolic extract of fruits was concentration-dependent and showed a correlation with total phenolic constituents of the respective *** on the results obtained,mulberry fruits were found to serve as a potential source of food diet and natural antioxidants.

关键词： Mulberry fruits Chemical composition 2 2-diphenyl-l-picrylhydrazyl (DPPH) radical scavenging activity Nutritional value. Pakistan

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Health economic evaluation of moist wound care in chronic cutaneous leishmaniasis ulcers in Afghanistan

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Infectious Diseases of Poverty 2018年第1期7卷 129-144页

作者： Hans-Christian Stahl faridullah Ahmadi Sami Mohammad Nahzat Heng-Jin Dong Kurt-Wilhelm Stahl Rainer Sauerborn Institute of Public Health University Hospital HeidelbergHeidelbergGermany Malaria and Leishmaniasis Centre Provincial Civil Balkh HospitalMazar-e-SharifAfghanistan National Malaria and Leishmaniasis Control Program Ministry of Public HealthKabulAfghanistan Center for Health Policy Studies School of MedicineZhejiang UniversityHangzhouChina NGO Waisenmedizin e.V.–Promoting Access to Essential Medicine FreiburgGermany

Background:The present health economic evaluation in Afghanistan aims to support public health decision makers and health care managers to allocate resources efficiently to appropriate treatments for cutaneous leishmaniasis(CL)elicited by Leishmania tropica or Leishmania ***:A decision tree was used to analyse the cost and the effectiveness of two wound care regimens versus intra-lesional antimony in CL patients in *** were collected from a societal *** was measured in wound free *** incremental cost-effectiveness ratio(ICER)and incremental net monetary benefit(NMB)were *** model was parameterized with baseline parameters,sensitivity ranges,and parameter ***,the model was simulated and results were evaluated with deterministic and probability sensitivity *** outcomes were the efficiency of the regimens and a budget impact analysis in the context of ***:Average costs per patients were US$11(SE=0.016)(Group I:Intra-dermal Sodium Stibogluconate[IL SSG]),US$16(SE=7.58)(Group II:Electro-thermo-debridement[ETD]+Moist wound treatment[MWT])and US$25(SE=0.48)(Group III:MWT)in patients with a single chronic CL *** a societal perspective the budget impact analysis shows that the regimens’drug costs are lower than indirect disease *** effectiveness in wound free days are 177(SE=0.36)in Group II,147(SE=0.33)in Group III,and 129(SE=0.27)in Group *** ICER of Group II versus Group I was US$0.09 and Group III versus Group I US$0.77,which is very costeffective with a willingness-to-pay threshold of US$2 per wound free *** a Monte-Carlo probabilistic sensitivity analysis Group II was cost-effective in 80%of the cases starting at a willingness-to-pay of 80 cent per wound free ***:Group II provided the most cost-effective *** non-treatment alternative is not an option in the management of chronic CL *** of Group III should at le

关键词： Cutaneous leishmaniasis Wound healing Cost-effectiveness Sodium Stibogluconate Moist wound treatment

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