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Pharmacological activity of Mentha longifolia and its phytoconstituents

Journal of Traditional Chinese Medicine 2017年第5期37卷 710-720页

作者： Mohammad Hosein Farzaei Roodabeh Bahramsoltani Ali Ghobadi Fatemeh Farzaei fariba najafi Medical Biology Research Center Kermanshah University of Medical Sciences Kermanshah *** Iran Pharmaceutical Sciences Research Center Kermanshah University of Medical Sciences Kermanshah *** Iran Department of Traditional Pharmacy School of Traditional Medicine Tehran University of Medical Sciences Tehran *** Iran School of Traditional Medicine Iran University of Medical Sciences Tehran *** Iran Kermanshah University of Medical Sciences Kermanshah *** Iran

Current paper reviews the pharmacological activities, therapeutic indications and phytochemicals of M. longifolia. This herb has been consumed traditionally for the treatment of various diseases, including gastrointestinal disorders, respiratory disorders, infectious diseases, inflammatory diseases, as well as menstrual disorders. In the modern era, various pharmacological activities have been confirmed for M. longifolia, such as anti-parasitic, antimicrobial, anti-insect, antimutagenic, antinociceptive, anti-inflammatory, antioxidant, keratoprotective, hepatoprotective, anti-diarrhea, and spasmolytic effects. The plant showed therapeutic benefits in irritable bowel syndrome, amenorrhea and oligomenorrhea, and oxidative stress-associated diseases as well. A vast variety of natural components such as flavonoids, phenolic acids, cinnamates, ceramides, sesquiterpenes, terpenes, and terpenoids have been suggested to be responsible for the pharmacological action of M. longifolia. These natural products can be considered as novel medicinal sources for developing new drugs. Further investigations to explore therapeutic efficacy, tolerability,and pharmaceutical properties of M. longifolia phytochemical agents are recommended.

关键词： Mentha Phytochemicals Ethnopharmacology Review

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