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Road safety data collection systems in Iran: A comparison based on relevant organizations

Chinese Journal of Traumatology 2020年第5期23卷 265-270页

作者： Homayoun Sadeghi-Bazargani Sakineh Sharifian Davoud Khorasani-Zavareh Raana Zakeri Mehdi Sadigh Mina Golestani Mousa Amiri Reza Masoudifar Farzad Rahmani Nasser Mikaeeli Javad Namvaran Khalil Pour-Ebrahim Mahdi Rezaei Babak Arabzadeh Bahram Samadirad Aliashraf Seyffarshad fariba mirza-mohammadi-teimorloue Shahin Kazemnezhad Soudabe Marin Saeede Sheikhi Reza mohammadi Research Center for Evidence-Based Medicine Tabriz University of Medical SciencesTabrizIran Department of Health in Emergencies and Disasters School of Public Health and SafetyShahid Beheshti University of Medical SciencesTehranIran Workplace Health Promotion Research Center(WHPRC) Department of Health in Emergencies and DisastersShahid Beheshti University of Medical SciencesTehranIran Department of Health Services Management Iranian International Safe Community Support CenterTabriz University of Medical SciencesTabrizIran Road Traffic Injury Research Center Tabriz University of Medical SciencesTabrizIran Iranian Traffic Police TehranIran University of Tabriz Islamic Azad TabrizIran Department of Emergency Medicine Road Traffic Injury Research CenterTabriz University of Medical SciencesTabrizIran Iranian Traffic Police TabrizIran Payame Noor University(PNU) TehranIran Karafarin Insurance TabrizIran Legal Medicine Research Center Legal Medicine OrganizationTehranIran Shohada Medical Research and Training Hospital Tabriz University of Medical SciencesTabrizIran Department of Biostatistics and Epidemiology School of HealthTabriz University of Medical SciencesTabrizIran Department of Neurobiology Care Sciences and Society(NVS)H1Division of Family Medicine and Primary CareHuddingeSweden

Purpose:Various organizations and institutions are involved in road traffic injury(RTI)and crash registration such as police,forensic medicine organization,hospitals and emergency medical *** there is a substantial uncertainty in interpreting the data,duplicated data collection and missing data in relation to RTI in most *** study aims to identify data sources for RTI surveillance in Iran and to explore traffic safety data source domains,data elements and detailed information by each data ***:This is a qualitative study which was conducted in 2017 in *** were collected employing semi-structured interviews with informants in road safety organizations in relation to traffic safety including Police,Ministry of Health and Medical Education as well as Forensic Medicine Organization and other *** completing the preliminary extraction information,the minimum data set was used and compared in each ***:Eight different organizations relevant to road traffic safety were *** main domain of data provided by each one consists of Emergency Medical System form,Police KAM114 form,Ministry of Transport and Road Administration,Red Crescent Organization/Disaster Management Information System,Ministry of Health and Medical Education,Forensic Medicine Organization,Insurance Company and Ministry of *** system has its own database,based upon its scope and mainly at crash and postcrash status and little on pre-crash ***:All current registry systems are not surveillance systems for RTI *** data have been collected in various registry systems in Iran,but most of the collected variables are duplicated in each *** the other hand,some variables like alcohol and substance abuse,child seat belt,helmet use in relation to RTI prevention are missed in all ***,it is a critical need to integrate and establish a comprehensive surveillance system,with focus on the

关键词： Accidents,traffic Integrated surveillance system Prevention and control

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BSN:Photometric Light Curve Analysis of Two Contact Binary Systems LS Del and V997 Cyg

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Research in Astronomy and Astrophysics 2024年第4期24卷 192-213页

作者： Atila Poro Mehmet Tanriver Elham Sarvari Shayan Zavvarei Hossein Azarara Laurent Corp Sabrina Baudart Asma Ababafi Nazanin Kahali Poor fariba Zare Ahmet Bulut Ahmet Keskin Astronomy Department of the Raderon AI Lab. BurnabyBC.Canada Department of Astronomy and Space Science Faculty of ScienceErciyes UniversityKayseri TR-38039Turkiye Erciyes University Astronomy and Space Science Observatory Application and Research CenterKayseri TR-38039Turkiye Independent Astrophysics Researcher TehranIran Department of Physics Shahid Beheshti UniversityTehranIran Faculty of Physics Shahid Bahonar University of KermanP.O.Box 76175KermanIran Double Stars Committee SociétéAstronomique de FranceParisFrance Dez Astronomical Association Khouzestan ProvinceDezfulIran Department of Physics Amirkabir University of TechnologyTehranIran Department of Physics Faculty of SciencesCanakkale Onsekiz Mart UniversityTerzioglu KampusuTR-17020CanakkaleTurkiye Astrophysics Research Center and Observatory Canakkale Onsekiz Mart UniversityTerzioğlu KampusuTR-17020CanakkaleTürkiye

The light curve analyses and orbital period variations for two contact binary stars,LS Del and V997 Cyg,are presented in this work which was conducted in the frame of the Binary Systems of South and North project Ground-based photometric observations were performed at two observatories in *** used the Transiting Exoplanet Survey Satellite(TESS)data for extracting times of minima and light curve analysis of the targe *** O-C diagram for both systems displays a parabolic *** Del and V997 Cyg’s orbital periods are increasing at rates of dP/dt=7.20×10^(-08)days yr^(-1)and dP/dt=2.54×10^(-08)days yr^(-1),respectively Therefore,it can be concluded that mass is being transferred from the less massive star to the more massive component with a rate of dM/dt=-1.96×10^(-7)M_(⊙)yr^(-1)for the LS Del system,and dM/dt=-3.83×10^(-7)M_(⊙)yr-1for V997 *** parameters of a third possible object in the system are also *** PHysics Of Eclipsing BinariEs Python code was used to analyze the light *** light curve solutions needed a cold starspot due to the asymmetry in the LS Del system’s light curve *** mass ratio fill-out factor,and star temperature all indicate that both systems are contact binary types in this *** methods were applied to estimate the absolute parameters of the systems:one method relied on the parallax of Gaia DR3,and the other used a P-M *** positions of the systems are also depicted on the M-L,M-R q-L_(ratio),and logM_(tot)-logJ_(0)*** recommend that further observations and investigations be done on the existence of a fourth body in this system.

关键词： (stars:)binaries:eclipsing methods:observational stars:individual(LS Del and V997 Cyg)

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Metabolic collaboration between cells in the tumor microenvironment has a negligible effect on tumor growth

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The Innovation 2024年第2期5卷 107-114页

作者： Johan Gustafsson fariba Roshanzamir Anders Hagnestål Sagar M.Patel Oseeyi I.Daudu Donald F.Becker Jonathan L.Robinson Jens Nielsen Department of Life Sciences Chalmers University of TechnologySE-41296 GothenburgSweden Hagnesia AB SE-43854 HindåsSweden Department of Biochemistry and Redox Biology Center University of Nebraska-LincolnLincolnNE 68588USA BioInnovation Institute DK2200 CopenhagenDenmark

The tumor microenvironment is composed of a complex mixture of different cell types interacting under conditions of nutrient deprivation,but the metabolism therein is not fully understood due to difficulties in measuring metabolic fluxes and exchange of metabolites between different cell types in ***-scale metabolic modeling enables estimation of such exchange fluxes as well as an opportunity to gain insight into the metabolic behavior of individual cell ***,we estimated the availability of nutrients and oxygen within the tumor microenvironment using concentration measurements from blood together with a metabolite diffusion *** addition,we developed an approach to efficiently apply enzyme usage constraints in a comprehensive metabolic model of human *** combined modeling reproduced severe hypoxic conditions and the Warburg effect,and we found that limitations in enzymatic capacity contribute to cancer cells’preferential use of glutamine as a substrate to the citric acid ***,we investigated the common hypothesis that some stromal cells are exploited by cancer cells to produce metabolites useful for the cancer *** identified over 200 potential metabolites that could support collaboration between cancer cells and cancer-associated fibroblasts,but when limiting to metabolites previously identified to participate in such collaboration,no growth advantage was *** work highlights the importance of enzymatic capacity limitations for cell behaviors and exemplifies the utility of enzyme-constrained models for accurate prediction of metabolism in cells and tumor microenvironments.

关键词： metabolism effect limitations

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Effects of L-carnitine on treatment outcomes of COVID-19 patients hospitalized in intensive care units:A double-blind randomized clinical trial

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Journal of Acute Disease 2024年第3期13卷 100-105页

作者： Hesameddin Modir Behnam Mahmoudieh Seyed Yousef Shahtaheri fariba Farokhi Department of Anesthesiology and Critical Care Arak University of Medical SciencesArakIran Clinical Research Development Valiasr HospitalArak University of Medical SciencesArakIran

Objective:To assess the effects of L-carnitine on the outcomes of patients with moderate to severe coronavirus disease 2019(COVID-19)in intensive care unit(ICU).Methods:This double-blind clinical trial was carried out in 2022-2023.64 Patients with COVID-19 were selected from Amiralmomenin and Khansari hospitals in Arak,*** were randomly assigned to the control and the L-carnitine treatment group via block *** blood gases,disease severity,and levels of D-dimer,lactate dehydrogenase,ferritin,and C-reactive protein were daily assessed during the seven days of the intervention,and the length of ICU stay,the need for endotracheal intubation,and mortality rate were ***:There were significant differences in length of ICU stay,the need for endotracheal intubation,and levels of D-dimer,lactate dehydrogenase,ferritin,APACHE栻score,and C-reactive protein between the two groups(P0.05).Conclusions:L-carnitine can improve outcomes of patients with ***,it can be used as an adjuvant therapy for these patients.

关键词： L-carnitine COVID-19 ICU Critically ill Mortality Clinical outcome

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Neuroprotective potential of traditional Ayurvedic Kadha:age-related neurological disorders:a comprehensive literature review

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Traditional Medicine Research 2024年第9期9卷 51-77页

作者： Sarvin Sadreddini Mohammad Javad Emami Kazemabad Sogand Sheikholeslami Kosar Chitzan-Zadeh Mohammad Taha Kouchaki Midia Rashidi Amir Abbas Ghayerin Shahin Sabaghi Ghazal Tavakoli Sepehr Nanbakhsh Tina Mansourian Arefeh Tabashiri fariba Arbab Mojeni Mohammed Namiq Amin Zahra Taheri Seyed Esmaeil Sedighi Taraneh Tarkashvand Parham Amirazodi Mobina Fathi Shirin Yaghoobpoor Niloofar Deravi School of Medicine Tabriz University of Medical SciencesTabriz ***Iran School of Medicine Qom University of Medical SciencesQom ***Iran School of Medicine Hamadan University of Medical SciencesHamadan ***Iran School of Medicine Ahvaz Jundishapur University of Medical SciencesAhvaz ***Iran Faculty of Medicine Tabriz University of Medical SciencesTabriz ***Iran School of Medicine Iran University of Medical SciencesTehran ***Iran School of Medicine Shahid Beheshti University of Medical SciencesTehran ***Iran School of Medicine Mazandaran University of Medical SciencesSari ***Iran School of Medicine Kermanshah University of Medical SciencesKermanshah ***Iran Faculty of Pharmacy Pharmaceutical Sciences BranchIslamic Azad UniversityTehran ***Iran Department of Biology Faculty of SciencePayamNoor UniversityTehran ***Iran Faculty of Medicine Islamic Azad University of Medical ScienceTehran 193951495Iran International Campus Shahid Sadoughi University of Medical SciencesYazd ***Iran

Despite modern medicine’s advancements,age-related neurological diseases like Alzheimer’s disease and Parkinson’s disease remain challenging due to high costs,side effects,and limited ***,a traditional Indian medicine system,offers Kadha tea as a potential herbal *** review explores Kadha’s components(basil(Ocimum basilicum L.),black pepper(Piper nigrum L.),Cinnamon(Cinnamomum verum ***),ginger(Zingiber officinale Roscoe),and raisin(Vitis vinifera L.))and their interaction with various neurological *** suggest Kadha exhibits anti-inflammatory,antioxidant,and antiviral properties,potentially impacting Alzheimer’s disease,Parkinson’s disease,neurotoxicity,neuroinflammation,and brain *** focusing on specific disease mechanisms and Kadha’s intergrade effects,this review aims to elucidate its potential role in managing age-related neurological disorders.

关键词： Ayurveda Kadha neuroprotective neurological disorders traditional medicine

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Thirty years of the human immunodeficiency virus epidemic and beyond

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International Journal of Oral Science 2013年第4期5卷 191-199页

作者： fariba S Younai Division of Oral Biology and Medicine School of DentistryUniversity of California

After more than 30 years of battling a global epidemic, the prospect of eliminating human immunodeficiency virus （HIV） as the most challenging infectious disease of the modern era is within our reach. Major scientific discoveries about the virus responsible for this immunodeficiency disease state, including its pathogenesis, transmission patterns and clinical course, have led to the development of potent antiretroviral drugs that offer great hopes in HIV treatment and prevention. Although these agents and many others still in development and testing are capable of effectively suppressing viral replication and survival, the medical management of HIV infection at the individual and the population levels remains challenging. Timely initiation of antiretroviral drugs, adherence to the appropriate therapeutic regimens, effective use of these agents in the pre and post-exposure prophylaxis contexts, treatment of comorbid conditions and addressin~ social and nsvcholo2ical factors involved in the care of individuals continue to be important considerations.

关键词： human immunodeficiency virus treatment prevention global impact antiretrovirals epidemiology

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Volumetric and ultrasonic properties of thiamine hydrochloride drug in aqueous solutions of choline-based deep eutectic solvents at different temperatures

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Chinese Journal of Chemical Engineering 2023年第10期62卷 21-30页

作者： Hemayat Shekaari fariba Ghaffari Masumeh Mokhtarpour Department of Physical Chemistry University of TabrizTabrizIran

Important efforts have been made over the past years to improve the drug acts,which leads to the discovery of novel drug preparations and delivery *** optimal design of such processes requires a molecular-level understanding of the interactions between drug molecules and biological *** thermodynamic investigation provides deep and complete knowledge of interactions and the choice of appropriate and suitable production compounds in pharmaceutical ***,the analysis of drugs+co-solvents in aqueous media is the central issue in many types of research because they exert their impact by interacting with biological *** work is aimed to measure the density and speed of sound for the thiamine hydrochloride in water+deep eutectic solvents(DESs)mixtures(choline chloride/urea,choline chloride/ethylene glycol and choline chloride/glycerol)at temperature range(293.15-308.15)*** correlation of the evaluated parameters in some standard relations,the partial molar parameters *** molar volumes,Vφ,m,and apparent molar isentropic compression,κ_(s,φ,m),are *** addition,apparent molar isobaric expansion,E^(0)_(φ,m),and Hepler’s constant are computed from the density and speed of sound *** fitting the experimental Vφ,m andκ_(s,φ,m)the Redlich-Meyer equation was employed that the important quantities;standard partial molar volume,V^(0)_(m),and partial molar isentropic compression,κφ,m0,were *** thermodynamic analysis of the studied system also plays a crucial role in the pharmaceutical industry.

关键词： Deep eutectic solvents Thiamine hydrochloride Density Speed of sound Redlich-Meyer equation

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Circulation cells topology and their effect on migration pattern of different multi-bend meandering rivers

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International Journal of Sediment Research 2020年第6期35卷 636-650页

作者： fariba Sadat Esfahani Alireza Keshavarzi Water Engineering Department Shiraz University Centre for Infrastructure Engineering School of EngineeringWestern Sydney University

In meandering rivers,a cross-stream flow,referred to as a secondary current,has important effects on broad spectra of hydraulic/environmental characteristics,running the gamut from river hydrodynamics and geomorphology to stream *** transport equation for vorticity and kinetic energy transfer should be analyzed to specify terms involved in generation of secondary ***,there is limited research on scrutinizing these terms in meandering *** the other hand,while rivers are mostly multi-bend,previous studies have been limited to single *** the current paper,three physical multi-bend channels representing a strongly curved bend,a mild bend and an elongated symmetrical meander loop are designed in order to unravel mechanisms responsible for forming circulation cells in cross *** are carried out in the middle bend of these *** turbulence anisotropy considerably strengthens almost all near bank ***,contrary to single sharp bends,multi bend effects hinder the transfer of the kinetic energy in both directions in the entrance section of the strongly curved bend.

关键词： Circulation cells Multi bend channels Vorticity equation Kinetic energy transfer

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Determination of Violet Covasol as a cosmetic dye in water samples by a CPE-Scanometry method

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Chinese Chemical Letters 2016年第5期27卷 659-665页

作者： Ardeshir Shokrollahi fariba Davoodi Kashkoli Department of Chemistry Yasouj University

The trace amounts of Violet Covasol as a cosmetic dye was determined by an efficient cloud point extraction-Scanometry （CPE-Scanometry） method. This method has many advantages such as novelty, facility, high speed, sensitivity, low cost and safety. The method is based on the CPE of an analyte from an aqueous solution, diluting the extracted surfactant-rich phase with ethanol, transferring to Plexiglas~ cell and scanning of the cells containing the analyte solution with a scanner and measuring the RGB parameters with software written in visual basic （VB 6） media. Parameters impacting the extraction efficiency such as pH of the system, the concentration of surfactant, equilibration temperature and time were optimized. Detection limit （DL）, relative standard deviation （RSD） and linear range for the proposed method are 0.026, 0.71 and 0.16-6.6 μg mL 1 respectively. The method was successfully applied for the determination of Violet Covasol dye in several water samples, including a water sample containing the dye as a tracer （to investigate subsurface water movement）.

关键词： Violet CovasolCosmetic dye CPE-Scanometry PlexiglasR cell

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Activity estimation in radioimmunotherapy using magnetic nanoparticles

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Chinese Journal of Cancer Research 2015年第2期27卷 203-208页

作者： Samira Rasaneh Hossein Rajabi fariba Johari Daha Department of Radioisotope Nuclear science and Technology Research Institute Department of Medical Physics School of Medical SciencesTarbiat Modares University

Objective： Estimation of activity accumulated in tumor and organs is very important in predicting the response of radiopharmaceuticals treatment. In this study, we synthesized ~77Lutetium （177Lu）-trastuzumabiron oxide nanoparticles as a double radiopharmaceutical agent for treatment and better estimation of organ activity in a new way by magnetic resonance imaging （MRI）. Methods： ^177Lu-trastuzumab-iron oxide nanoparticles were synthesized and all the quality control tests such as labeling yield, nanoparticle size determination, stability in buffer and blood serum up to 4 d, immunoreactivity and biodistribution in normal mice were determined. In mice bearing breast tumor, liver and tumor activities were calculated with three methods： single photon emission computed tomography （SPECT）, MRI and organ extraction, which were compared with each other. Results： The good results of quality control tests （labeling yield： 61%±2%, mean nanoparticle hydrodynamic size： 41±15 nm, stability in buffer： 86%±5%, stability in blood serum： 80%±3%, immunoreactivity： 80%±2%） indicated that ^177Lu-trastuzumab-iron oxide nanoparticles could be used as a double radiopharmaceutical agent in mice bearing tumor. Results showed that ^177Lu-trastuzumab-iron oxide nanoparticles with MRI had the ability to measure organ activities more accurate than SPECT. Conclusions： Co-conjugating radiopharmaceutical to MRI contrast agents such as iron oxide nanoparticles may be a good way for better dosimetry in nuclear medicine treatment.

关键词： Radioimmunotherapy (RIT) activity estimation lutetium-177 herceptin magnetic nanoparticles magnetic resonance imaging (MRI)

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