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Open Journal of Medical Microbiology 2015年第4期5卷 254-258页

作者： Aleksey Shatalov fares awwad Pablo Mangue Rami Juden Foqahaa Department of Microbiology La Paz Medical Center Malabo Equatorial Guinea Department of Neonatology and Pediatria La Paz Medical Center Malabo Equatorial Guinea

The study was conducted on new-born babies in whom septicemia was suspected, to determine the prevalence of bacterial strains isolated and their sensitivity to antimicrobial drugs. The study was carried out at La Paz Medical Center, Microbiology section, Malabo, Equatorial Guinea from August 2013 to October 2015. Out of 293 septicemia suspected cases, 29 (10%) blood cultures were positive, 28 with bacterial growth and 1 with growth of Candida sp. The mortality rate of neonates caused by Gram negative bacterial sepsis was 34.7%. Among the Gram negative bacteria (24 isolates), the most common types were Klebsiella pneumoniae (16 = 69.6%), followed by Escherichia coli (4 = 17.4%) and Acinetobacter species (4 = 17.4%). Four Gram positive bacteria were also isolated and identified all ascoagulase-negative staphylococci. All the Klebsiella pneumoniae isolates and Acinetobacter species demonstrated Multi Drug Resistance against different antibiotics with Extended-spectrum β-lactamase (ESBL) activity. The most frequent causative agent of bacterial sepsis in new-born children was Klebsiella pneumoniae. An alarming level of Multi Drug Resistance (MDR) Klebsiella pneumoniae strains to the first choice antibiotic treatment was observed.

关键词： Sepsis New-Born Multi Drug Resistance Equatorial Guinea Klebsiella pneumoniae

Cardiac differentiation is modulated by anti-apoptotic signals in murine embryonic stem cells

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World Journal of Stem Cells 2024年第5期16卷 551-559页

作者： Amani Yehya Joseph Azar Mohamad Al-fares Helene Boeuf Wassim Abou-Kheir Dana Zeineddine Ola Hadadeh Department of Anatomy Cell Biology and Physiological SciencesAmerican University of BeirutBeirut 1107-2020Lebanon Inserm BiotisU1026University BordeauxBordeaux F-33000France Rammal Rammal Lab Physio-Toxicity Environmental TeamFaculty of SciencesLebanese UniversityNabatieh 0000Lebanon

BACKGROUND Embryonic stem cells(ESCs)serve as a crucial ex vivo model,representing epiblast cells derived from the inner cell mass of blastocyst-stage *** exhibit a unique combination of self-renewal potency,unlimited proliferation,and *** latter is evident by the ability of the isolated cells to differ-entiate spontaneously into multiple cell lineages,representing the three primary embryonic germ *** regulatory networks guide ESCs,directing their self-renewal and lineage-specific ***,or programmed cell death,emerges as a key event involved in sculpting and forming various organs and structures ensuring proper embryonic ***-ever,the molecular mechanisms underlying the dynamic interplay between diffe-rentiation and apoptosis remain poorly *** To investigate the regulatory impact of apoptosis on the early differentiation of ESCs into cardiac cells,using mouse ESC(mESC)models-mESC-B-cell lym-phoma 2(BCL-2),mESC-PIM-2,and mESC-metallothionein-1(MET-1)-which overexpress the anti-apoptotic genes Bcl-2,Pim-2,and Met-1,*** mESC-T2(wild-type),mESC-BCL-2,mESC-PIM-2,and mESC-MET-1 have been used to assess the effect of potentiated apoptotic signals on cardiac *** hanging drop method was adopted to generate embryoid bodies(EBs)and induce terminal differentiation of *** size of the generated EBs was measured in each condition compared to the wild *** the functional level,the percentage of cardiac differentiation was measured by calculating the number of beating cardiomyocytes in the manipulated mESCs compared to the *** the molecular level,quantitative reverse transcription-polymerase chain reaction was used to assess the mRNA expression of three cardiac markers:Troponin T,GATA4,and ***,troponin T protein expression was evaluated through immunofluorescence and western blot *** Our findings showed that the upregulation of Bcl-

关键词： Mouse embryonic stem cells Self-renewal Apoptosis Cardiac differentiation B-cell lymphoma 2 PIM-2 Metallothionein-1

Outcomes of endoscopic submucosal dissection in cirrhotic patients: First American cohort

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World Journal of Hepatology 2024年第5期16卷 784-790页

作者： Robert Luke Pecha fares Ayoub Ankur Patel Abdullah Muftah Michael W Wright Mai A Khalaf Mohamed O Othman Department of Gastroenterology and Hepatology UC DavisSacramentoCA 95817United States Department of Gastroenterology and Hepatology Baylor College of MedicineHoustonTX 77030United States Internal Medicine Baylor College of MedicineHoustonTX 77030United States Department of Gastroenterology and Hepatology University of Texas Medical Branch at GalvestonGalvestonTX 77550United States Medical School Baylor College of MedicineHoustonTX 77030United States Department of Tropical Medicine Tanta UniversityTanta 31527Egypt

BACKGROUND Among patients with cirrhosis and pre-malignant or early malignant mucosal lesions,surgical intervention carries a much higher bleeding *** such lesions are discovered,endoscopic submucosal dissection(ESD)may offer curative therapy with lower risks than surgery and improved outcomes compared to traditional endoscopic *** To evaluate the outcomes of ESD in patients with *** Patients with cirrhosis undergoing ESD between July 2015 and August 2022 were retrospectively matched in 1:2 fashion to controls based on lesion location,size,and anticoagulation *** outcomes were compared between *** A total of 64 Lesions from 59 patients were included(16 cirrhosis,43 control).There were no differences in patient or lesion characteristics between *** bloc and curative resection was achieved in 84.21%,78.94%of the cirrhosis group and 88.89%,68.89%of controls,respectively,with no significant *** patients had significantly higher rates of intra-procedural coagulation grasper use for control of bleeding(47.37%vs 20%;P=0.02).There were otherwise no significant differences in adverse event *** the 29 patients with follow up,we found higher rates of recurrence in the cirrhosis group compared to controls(40%vs 5.26%;P=0.019),however this effect did not persist on multivariable analysis controlling for known *** ESD may be safe and effective in patients with *** procedure related outcomes were not significantly different between ***-procedural bleeding requiring use of the coagulation grasper use was expectedly higher in the cirrhosis group given the known effects of liver disease on hemostasis.

关键词： Endoscopic aubmucosal dissection Cirrhosis Advanced polypectomy Intraprocedural bleeding Colon cancer

Accelerating Large-Scale Sorting through Parallel Algorithms

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Journal of Computer and Communications 2024年第1期12卷 131-138页

作者： Yahya Alhabboub fares Almutairi Mohammed Safhi Yazan Alqahtani Adam Almeedani Yasir Alguwaifli College of Computer Science and Information Technology Imam Abdulrahman Bin Faisal University Dammam Saudi Arabia

This study explores the application of parallel algorithms to enhance large-scale sorting, focusing on the QuickSort method. Implemented in both sequential and parallel forms, the paper provides a detailed comparison of their performance. This study investigates the efficacy of both techniques through the lens of array generation and pivot selection to manage datasets of varying sizes. This study meticulously documents the performance metrics, recording 16,499.2 milliseconds for the serial implementation and 16,339 milliseconds for the parallel implementation when sorting an array by using C++ chrono library. These results suggest that while the performance gains of the parallel approach over its serial counterpart are not immediately pronounced for smaller datasets, the benefits are expected to be more substantial as the dataset size increases.

关键词： Sorting Algorithm Quick Sort QuickSort Parallel Parallel Algorithms

Outpatient insulin use in type 2 diabetes mellitus and acute respiratory distress syndrome outcomes:A retrospective cohort study

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World Journal of Clinical Cases 2024年第17期12卷 2966-2975页

作者： Georges Khattar Samer Asmar Laurence Aoun fares Saliba Shaza Almardini Saif Abu Baker Catherine Hong Carolla El Chamieh Fadi Haddadin Toni Habib Omar Mourad Zeina Morcos Fatema Arafa Jonathan Mina Khalil El Gharib Mohammad Aldalahmeh Salman Khan Elie Bou Sanayeh Department of Medicine Holy Spirit University of KaslikJounieh 00000Lebanon Department of Internal Medicine Staten Island University HospitalStaten IslandNY 10305United States Public Heath and Biostatistics Independent ResearchBeirut 0000Lebanon Department of Medicine Lebanese UniversityBeirut 00000Lebanon Department of Medicine University of BalamandBeirut 00000Lebanon Department of Medicine Lebanese American UniversityBeirut 00000Lebanon Department of Medicine Northwell Health Staten Island University HospitalNew YorkNY 10305United States

BACKGROUND The impact of type 2 diabetes mellitus(T2DM)on acute respiratory distress syndrome(ARDS)is debatable.T2DM was suspected to reduce the risk and complications of ***,during coronavirus disease 2019(COVID-19),T2DM predisposed patients to ARDS,especially those who were on insulin at *** evaluate the impact of outpatient insulin use in T2DM patients on non-COVID-19 ARDS *** We conducted a retrospective cohort analysis using the Nationwide Inpatient Sample *** patients diagnosed with ARDS were stratified into insulin-dependent diabetes mellitus(DM)(IDDM)and non-insulindependent DM(NIDDM)*** applying exclusion criteria and matching over 20 variables,we compared cohorts for mortality,duration of mechanical ventilation,incidence of acute kidney injury(AKI),length of stay(LOS),hospitalization costs,and other clinical *** Following 1:1 propensity score matching,the analysis included 274 patients in each ***,no statistically significant differences emerged between the IDDM and NIDDM groups in terms of mortality rates(32.8%vs 31.0%,P=0.520),median hospital LOS(10 d,P=0.537),requirement for mechanical ventilation,incidence rates of sepsis,pneumonia or AKI,median total hospitalization costs,or patient disposition upon *** Compared to alternative anti-diabetic medications,outpatient insulin treatment does not appear to exert an independent influence on in-hospital morbidity or mortality in diabetic patients with non-COVID-19 ARDS.

关键词： Acute respiratory distress syndrome Type 2 diabetes mellitus Insulin Length of stay Mortality Endotracheal intubation Acute kidney injury Coronavirus disease 2019

Guidelines on cholangioscopy for indeterminate biliary strictures:one step closer to consensus

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Hepatobiliary Surgery and Nutrition 2023年第5期12卷 776-779页

作者： fares Ayoub Mohamed O.Othman Section of Gastroenterology Hepatology&NutritionBaylor College of MedicineHoustonTXUSA

Described as early as the 1950s(1),cholangioscopy has evolved from a burdensome intra-operative maneuver performed during open surgery,to a minimally-invasive,widely-available tool that can be utilized on demand during endoscopic retrograde cholangiopancreatography(ERCP).The advent of the latest generation digital cholangioscopes with improved image quality,maneuverability,and the ability to pass tools through a dedicated instrument channel has revolutionized the modern approach to a wide variety of biliary disorders(2).

关键词： Cholangioscopy endoscopic retrograde cholangiopancreatography(ERCP) biliary strictures per-oral cholangioscopy(POC) indeterminate stricture cholangiocarcinoma

YOLO and Blockchain Technology Applied to Intelligent Transportation License Plate Character Recognition for Security

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Computers, Materials & Continua 2023年第12期77卷 3697-3722页

作者： fares Alharbi Reem Alshahrani Mohammed Zakariah Amjad Aldweesh Abdulrahman Abdullah Alghamdi Department of Computer Science College of Computing and ITShaqra UniversityShaqra15526Saudi Arabia Department of Computer Science College of Computers and ITTaif UniversityP.O.Box 11099Taif21944Saudi Arabia College of Computer and Information Science King Saud UniversityRiyadhSaudi Arabia

Privacy and trust are significant issues in intelligent transportation systems(ITS).Data security is critical in ITS systems since sensitive user data is communicated to another user over the internet through wireless devices and routes such as radio channels,optical fiber,and blockchain *** Internet of Things(IoT)is a network of connected,interconnected *** issues occasionally arise due to the amount of data ***,they have been primarily addressed by blockchain and smart contract *** there are still security issues with smart contracts,primarily due to the complexity of writing the code,there are still many challenges to consider when designing blockchain designs for the IoT *** study uses traditional blockchain technology with the“You Only Look Once”(YOLO)object detection method to accurately locate and identify license *** YOLO and blockchain technologies used for intelligent vehicle license plate recognition are promising,they have received limited research ***-time object identification and recognition would be possible by combining a cutting-edge object detection technique with a regional convolutional neural network(RCNN)built with the tensor flow core open source *** method works reasonably well for identifying any license *** Automatic License Plate Recognition(ALPR)approach delivered outstanding results in various ***,with a recognition rate of 96.2%,our system(UFPR-ALPR)surpassed the previously used technology,consisting of 4500 frames and around 150 ***,a deep learning algorithm was trained to recognize images of license plate numbers using the UFPR-ALPR ***,the license plate’s characters were complicated for standard methods to identify because of the shifting lighting *** proposed model,however,produced beneficial outcomes.

关键词： Intelligent transportation system blockchain technology license plate recognition privacy YOLO deep learning technique ALPR

Ventral Hernia: An Innovative Grading System

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International Journal of Clinical Medicine 2022年第5期13卷 204-211页

作者： fares Alghamdi MBBS—Independent Researcher Baljurashi Saudi Arabia

Background: Ventral hernia is a complex and progressive condition that may lead to serious complications. However, no specified grading or classifying system is found to categorize the hernia, which leads to clinical complexities and may affect the patient outcome. Aim: The general aim of this paper is to build up an easy and comprehensive grading system to categorize ventral hernia. Methodology: By carrying out a secondary search over clinical presentation, physical examination, and imaging studies of ventral hernia, a valid grading system is developed. Results: Hanoon’s grading system is composed of seven grades, grades 1, 2A, 2B, 3A, 3B, 3C, and 4. Each grade entailed different clinical presentations, imaging characteristics, and progressivity of ventral hernia. Conclusion: Hanoon’s grading system for ventral hernia can be used to solve the clinical complexities of ventral hernia. Also, it can be a step forward in hernia research to build upon.

关键词： General Surgery Hernia Classification Grading

ON THE KINETICS AND MECHANISM OF THE COPOLYMERIZATION OF ACRYLONITRILE WITH STYRENE IN THE PRESENCE OF COPPER CHLORIDE

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Chinese Journal of Polymer Science 2003年第1期21卷 57-64页

作者： Mohammad M.fares Department of Applied Chemistry Jordan University of Science & Technology P. O. Box 3030 Irbid 22110 Jordan

The copolymerization of styrene (St) and acrylonitrile (AN) complexed with CuCl_2 monomer by a free radicalmechanism was performed using benzoyl peroxide as an initiator at 65℃ under N_2 atmosphere for 150 min. The rate ofpolymerization (R_p) was found to increase linearly with the concentration (in mol/L) of CuCl_2, AN and St through scalingrelations. The activation energy of the copolymerization process in the presence and absence of CuCl_2 was found to be46.5 kJ/mol and 102 kJ/mol, respectively. The viscosity average molecular weigh of the copolymer and the k_p^2/k_t ratio weredctermired to further assess the accelerating effect of CuCl_2 on the copolymerization process. The copolymerization processin the presence of CuCl_2 has a radical complex mechanism.

关键词： Rate of polymerization (R_p) Scaling relations Viscosity average molecular weight Radical complex mechanism

Unified Analysis for Calculating the Incoherent Spontaneous Emission of Cooperative Radiations

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Chinese Physics Letters 2017年第11期34卷 20-23页

作者： Hesham fares Enrica Chiadroni INFN-LNF Department of Physics Faculty of Science Assiut University

A unified analysis is presented to calculate the incoherent spontaneous power of cooperative radiations based on self-amplified spontaneous emission. Using quantum mechanical tools, we derive analytical expressions for the incoherent spontaneous power of undulator and Cherenkov free-electron lasers （FELs）. The undulator and Cherenkov FELs are considered as two different examples for the radiation that accumulate cooperatively. In the case of the undulator FEL, we show an excellent agreement between an expression for the incoherent radiation power derived in the present work and that obtained using a completely different approach [Phys. Ftev. E 65 （2002） 026501]. For the Cherenkov radiation, we demonstrate a satisfactory agreement between the incoherent power predicted in our analysis and previous experimental results.

关键词： In Unified Analysis for Calculating the Incoherent Spontaneous Emission of Cooperative Radiations