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青少年柔韧性扁平足距下关节制动术长期疗效与韧带松弛程度的相关性

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中华骨与关节外科杂志 2024年第4期17卷 347-353页

作者：潘旭月魏芳远陈卫衡北京中医药大学第三附属医院手足外科北京100029 “中医骨伤治疗与运动康复智能化”教育部工程研究中心北京100029

目的:探讨青少年柔韧性扁平足距下关节制动术长期疗效与韧带松弛程度的相关性。方法:回顾性纳入2016年1月至2018年6月行距下关节制动术治疗的74例青少年柔韧性扁平足患者,根据评价韧带松弛程度的Beighton评分分为≥4分的韧带松弛组40例... 详细信息

目的:探讨青少年柔韧性扁平足距下关节制动术长期疗效与韧带松弛程度的相关性。方法:回顾性纳入2016年1月至2018年6月行距下关节制动术治疗的74例青少年柔韧性扁平足患者,根据评价韧带松弛程度的Beighton评分分为≥4分的韧带松弛组40例、<4分的非韧带松弛组34例,探讨Beighton评分与末次随访时疼痛视觉模拟评分(VAS)、足踝能力评分(FAAM)、距舟覆盖角、距骨第1跖骨角、距骨第2跖骨角、Meary角、跟骨倾斜角的相关性。结果:74例患者获得54~65个月随访,平均随访(59.2±4.7)个月。非韧带松弛组患者末次随访时VAS评分、FAAM评分、距舟覆盖角、距骨第1跖骨角、距骨第2跖骨角、Meary角、跟骨倾斜角均明显优于韧带松弛组(P均<0.001)。韧带松弛组患者的Beighton评分与手术疗效相关指标存在相关性;非韧带松弛组患者的Beighton评分与手术疗效相关指标无相关性。结论:对于青少年柔韧性扁平足患者,当Beighton评分≥4分诊断为韧带松弛症时,行距下关节制动术的远期疗效与Beighton评分呈负相关,且疗效不及Beighton评分<4分的非韧带松弛症患者。建议青少年柔韧性扁平足患者术前进行韧带松弛程度的Beighton评分,对于韧带松弛症的该类患者谨慎考虑行距下关节制动术。

关键词：青少年柔韧性扁平足距下关节制动术韧带松弛症

Scarf截骨治疗跖内收型青少年外翻的早期疗效

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中华骨科杂志 2024年第5期44卷 302-307页

作者：祁印泽唐广君李昕宇魏芳远北京中医药大学第三附属医院手足外科北京100029 北京中医药大学北京100029

目的探讨Scarf截骨术治疗跖内收型青少年外翻的早期疗效。方法回顾性分析2022年7月至2023年8月北京中医药大学第三附属医院手足外科采用Scarf截骨术治疗的跖骨内收型青少年外翻患者20例,男4例、女16例,年龄(16.2±2.4)岁(范围14~19岁),... 详细信息

目的探讨Scarf截骨术治疗跖内收型青少年外翻的早期疗效。方法回顾性分析2022年7月至2023年8月北京中医药大学第三附属医院手足外科采用Scarf截骨术治疗的跖骨内收型青少年外翻患者20例,男4例、女16例,年龄(16.2±2.4)岁(范围14~19岁),双足10例、单足10例。术中截骨前先松解外侧关节囊、籽骨悬韧带、收肌,于第一跖骨干部做"Z"形截骨,将截骨远端做一定程度短缩、截除楔形骨块,利用平移和旋转将第一跖骨向第二跖骨方向推挤直至挤压第二跖骨头,减小跖内收角度。比较术前、术后即刻、末次随访时的外翻角、第一、二跖骨间角、跖内收角、第二至五跖骨间角及疼痛视觉模拟评分(visual analogue scale,VAS)。结果20例患者均顺利完成手术,切口均愈合良好,无一例发生感染。截骨端临床愈合时间为(5.1±0.7)周(范围4.1~6.6周)。所有患者均获得随访,随访时间(12.0±5.4)个月(范围2~18个月)。术前、术后即刻、末次随访时外翻角分别为35.40°±5.45°、6.93°±3.60°、9.83°±2.65°,差异有统计学意义(F=289.214,P<0.001);第一、二跖骨间角分别为11.50°(9.75°,14.00°)、1.50°(0.00°,2.00°)、1.50°(0.00°,2.00°),差异有统计学意义(H=53.255,P<0.001);跖内收角分别为22.80°±2.60°、20.63°±2.27°、20.67°±2.20°,差异有统计学意义(F=47.041,P<0.001);第二至五跖骨间角分别为19.03°±1.85°、15.37°±1.33°、16.03°±1.73°,差异有统计学意义(F=74.450,P<0.001)。术后所有指标均较术前改善,其中外翻角末次随访时与术后即刻的差异有统计学意义(P<0.05)。术前、术后6~8周的VAS评分分别为(2.60±1.64)分、(1.30±0.92)分,差异有统计学意义(t=4.330,P<0.001)。随访期间无一例发生转移性跖骨痛和复发内翻。结论采用Scarf截骨术治疗跖内收型外翻可有效矫正第一跖骨内收,同时对其余跖骨的内收状态有不同程度的改善效果,术后早期疗效满意。

关键词：青少年外翻截骨术

多口引流清创配合胫骨横向骨搬移术治疗Wagner Ⅲ级与Ⅳ级糖尿病足的疗效观察

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中华骨与关节外科杂志 2024年第4期17卷 340-346页

作者：祁印泽潘旭月朱瑞征梁欢邓品魏芳远北京中医药大学第三附属医院手足外科北京100029 “中医骨伤治疗与运动康复智能化”教育部工程研究中心北京100029 北京中医药大学北京100029 北京市隆福医院骨科北京100010 中国中医科学院中医基础理论研究所北京100700

目的:观察多口引流清创配合胫骨横向骨搬移术(TTBT)治疗糖尿病足的临床疗效。方法:回顾性分析2020年10月至2023年3月收治的Wagner Ⅲ级与Ⅳ级糖尿病足患者21例,男10例、女11例,年龄28~81岁,平均(55.8±20.7)岁。全部采用多口引流清创配... 详细信息

目的:观察多口引流清创配合胫骨横向骨搬移术(TTBT)治疗糖尿病足的临床疗效。方法:回顾性分析2020年10月至2023年3月收治的Wagner Ⅲ级与Ⅳ级糖尿病足患者21例,男10例、女11例,年龄28~81岁,平均(55.8±20.7)岁。全部采用多口引流清创配合TTBT治疗,记录从多口引流清创到白细胞计数恢复至11.0×10^(9)/L以下的时间、C反应蛋白水平恢复至10 mg/L以下所需时间,肿胀明显消退、脓性分泌物明显减少所需时间,以及创面愈合时间;并对不同Wagner分级、不同年龄、不同白蛋白水平进行分组,比较白细胞计数恢复时间、C反应蛋白水平恢复时间、肿胀明显消退的时间、脓性分泌物明显减少的时间、创面愈合时间。结果:随访时间3~24个月,平均(6.0±4.1)个月。多口引流清创配合TTBT治疗糖尿病足可以促进白细胞计数、C反应蛋白水平恢复正常,促进肿胀消退和减少脓性分泌物,促进创面愈合。WagnerⅢ级和Ⅳ级糖尿病足患者中,白细胞计数恢复时间、C反应蛋白水平恢复时间、肿胀明显消退时间、脓性分泌物明显减少时间、创面愈合时间的差异均无统计学意义(P均>0.05);不同年龄分组患者中,白细胞计数恢复时间、C反应蛋白水平恢复时间、肿胀明显消退时间、脓性分泌物明显减少时间、创面愈合时间的差异均有统计学意义(P均<0.05);不同白蛋白水平分组患者中,仅脓性分泌物明显减少的时间比较差异有统计学意义(P<0.05)。结论:多口引流清创配合TTBT治疗糖尿病足的临床疗效满意。初步认为糖尿病足的预后与患者年龄、白蛋白水平相关。

关键词：糖尿病足胫骨横向骨搬移术多口引流

选择性钙通道拮抗剂辅助治疗对溃疡性结肠炎患者血清炎性因子及肠道菌群的影响研究

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黑龙江医学 2024年第2期48卷 143-145页

作者：魏方圆范智博仝甲钊河南大学第一附属医院河南开封475000

目的:探索选择性钙通道拮抗剂(SCCBs)辅助治疗对溃疡性结肠炎(UC)患者血清炎性因子及肠道菌群的影响。方法:选取2018年2月—2020年3月河南大学第一附属医院收治的86例UC患者作为研究对象,采用区组随机化法分为参照组与试验组,每组各43... 详细信息

目的:探索选择性钙通道拮抗剂(SCCBs)辅助治疗对溃疡性结肠炎(UC)患者血清炎性因子及肠道菌群的影响。方法:选取2018年2月—2020年3月河南大学第一附属医院收治的86例UC患者作为研究对象,采用区组随机化法分为参照组与试验组,每组各43例。参照组予以常规治疗,试验组在参照组基础上予以相应的SCCBs辅助治疗,比较两组患者治疗前后的血清炎性因子[白细胞介素-6(IL-6)、白细胞介素-8(IL-8)、C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)]水平、肠道菌群水平及超氧化物歧化酶(SOD)、丙二醛(MDA)水平。结果:治疗后,两组患者IL-6、IL-8、CRP及TNF-α水平均有所降低,且试验组患者IL-6、IL-8、CRP及TNF-α水平均显著低于参照组,差异有统计学意义(t=6.735、8.374、7.518、6.840,P<0.05)。治疗后,两组患者乳酸菌、肠球菌及双歧杆菌水平均有所提升,且试验组患者乳酸菌、肠球菌及双歧杆菌水平均显著高于参照组,差异有统计学意义(t=9.612、9.381、6.187,P<0.05)。治疗后,试验组患者SOD水平显著高于参照组,差异有统计学意义(t=7.549,P<0.05),试验组患者MDA水平显著低于参照组,差异有统计学意义(t=9.835,P<0.05)。结论:SCCBs辅助治疗应用于UC患者中,能够有效缓解患者的机体炎性反应,调节其肠道菌群,促进其结肠正常生理功能的恢复。

关键词：溃疡性结肠炎选择性钙通道拮抗剂辅助治疗血清炎性因子肠道菌群

基于中医辨证分型应用中药外用制剂促进糖尿病足溃疡愈合的临床研究

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中国中医骨伤科杂志 2024年第1期32卷 36-41页

作者：潘旭月陈兆军祁印泽魏芳远北京中医药大学第三附属医院手足外科北京100029

目的:探讨基于中医辨证分型应用中药外用制剂促进糖尿病足溃疡愈合的疗效。方法:选取2019年7月至2022年7月住院的糖尿病足患者,随机分为治疗组和对照组。治疗组根据中医三期辨证分型,采用清创换药+相应中药外用制剂,对照组采用单纯清创... 详细信息

目的:探讨基于中医辨证分型应用中药外用制剂促进糖尿病足溃疡愈合的疗效。方法:选取2019年7月至2022年7月住院的糖尿病足患者,随机分为治疗组和对照组。治疗组根据中医三期辨证分型,采用清创换药+相应中药外用制剂,对照组采用单纯清创换药的方法。对比观察两组患者在临床综合疗效、患肢疼痛视觉模拟量表(VAS)评分、创面愈合时间等结果的差异。结果:纳入符合标准的病例90例,其中治疗组及对照组各45例,两组病例基本资料及病情差异无统计学意义(P>0.05)。临床综合疗效方面:治疗组治愈13例,显效25例,有效3例,无效4例,总有效率为91%;对照组治愈5例,显效20例,有效2例,无效18例,总有效率为60%,两组疗效比较差异有统计学意义(P0.05)。结论:根据中医三期辨证分型来合理应用中药外用制剂可促进糖尿病足溃疡愈合。

关键词：中药外用糖尿病足辨证分型

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从路线穿越巨型古滑坡谈山区公路地质选线

山西建筑 2024年第10期50卷 68-71页

作者：李耀华林荣团侯鹏飞黎俊杰韦芳元广西交通设计集团有限公司广西南宁530029 广西农业职业技术大学广西南宁530009

山区公路中,复杂地形、地貌、工程地质条件、场地环境等极大的影响着公路线位确定。以蒙象路为依托,基于白石巨型古滑坡两阶段勘察成果,以地质选线作为主要手段对项目白石古滑坡路段进行两阶段方案比选,包含线位工程地质条件、路基与桥... 详细信息

山区公路中,复杂地形、地貌、工程地质条件、场地环境等极大的影响着公路线位确定。以蒙象路为依托,基于白石巨型古滑坡两阶段勘察成果,以地质选线作为主要手段对项目白石古滑坡路段进行两阶段方案比选,包含线位工程地质条件、路基与桥梁的工程类型适应性等内容,最终采用在初设E线方案基础上优化后的A线方案,在项目已施工完成通车情况下验证了前期地质选线实践的合理性,进而引伸出山区公路地质选线综合性要点。公路地质选线应以地形、地质条件为基础进行综合性选线及精细化选线,产生最优解以确定最终路线方案;对于选线中遇到大型不良地质体情况,应查明其规模、性质等,合理评价其现状和实施工程建设后的整体及分区稳定性,有条件时可谨慎通过,必要时应采用适宜的工程措施。

关键词：山区公路巨型古滑坡地质选线不良地质方案比选

Water quality and habitat drive phytoplankton taxonomic and functional group patterns in the Yangtze River

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Ecological Processes 2024年第1期13卷 144-158页

作者： Wenqi Gao fangyuan Xiong Ying Lu wei Xin Haihua Wang Gangpeng Feng Chiping Kong Lei Fang Xiaoping Gao Yushun Chen State Key Laboratory of Freshwater Ecology and Biotechnology Institute of Hydrobiology Chinese Academy of Sciences University of Chinese Academy of Sciences Jiangxi Institute for Fisheries Sciences Poyang Lake Fisheries Research Centre of Jiangxi Province East China Sea Fisheries Research Institute Chinese Academy of Fishery Sciences Jiujiang Institute of Agricultural Sciences

Background Although phytoplankton are important primary producers in food webs, they are relatively less studied in large rivers compared to other types of systems. To fill this research gap, we studied phytoplankton taxonomic and functional composition and their relationships with water quality, habitat, climate, and land use across 30 river sections in the middle and lower reaches of the Yangtze River during 2017–*** Major observed phytoplankton groups were cyanobacteria, bacillariophyta, and chlorophyta. Phytoplankton total abundance, total biomass, and species richness significantly decreased in the dry season compared to the wet season, with the species and functional composition differing significantly between seasons. Phytoplankton species differences between seasons were mainly contributed by Oscillatoria sp., Pseudanabaena sp., and Melosira granulata. The dfferences in phytoplankton functional groups between seasons were mainly contributed by P（including Closterium sp., Melosira sp.）, Lo（including Merismopedia sp., Peridinium sp., Ceratium sp., and Gymnodinium sp.）, and J（including Pediastrum sp., Tetraedron sp., Crucigenia sp., Scenedesmus sp., and Coelastrum sp.）. The variance partitioning showed that water quality（NO3-N, total suspended solids, turbidity） and habitat（water flow, river bank and river channel conditions） were critical factors in shaping phytoplankton patterns, followed by climate and land *** Results indicated that there was significant seasonal variation of phytoplankton in the Yangtze River, with water quality and habitat primarily driving phytoplankton patterns. Our study contributes to the understanding of natural and anthropogenic factors that drive seasonal successional processes of phytoplankton in the Yangtze River. These findings have important implications for environmental management as well as towards the ecological restoration of large rivers.

关键词： Yangtze River Phytoplankton Functional group Water quality Physical habitat

International standard of Traditional Chinese Medicine Techniques: Traditional Chinese Medicine guidelines for acute primary headache(2022)

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Journal of Traditional Chinese Medicine 2024年第4期44卷 839-850页

作者： YAO Yuning CAO Kegang ZHANG Genming LIU Jianping CHEN wei CAO Junling YANG Wenming YAN Yongmei GENG Chang JU Yi ZHAO Dexi QU Miao LI Xiaoli SUN Li HAN Zhenyun HE Liyun CUI fangyuan FU Caihong ZHOU Bo LIAO Shuqin Department of Neurology Dongzhimen Hospital of Beijing University of Chinese MedicineBeijing 100007China Centre for Evidence-Based Chinese Medicine Beijing University of Chinese MedicineBeijing 100029Chin Encephalopathy center First Affiliated Hospital of Anhui University of Chinese MedicineHefei 230031China Department of Neurology Affiliated Hospital of Shaanxi University of Chinese MedicineXi'an 710077China Department of Neurology Beijing Changping District Hospital of Traditional Chinese MedicineBeijing 102299China Neurology center Beijing Tiantan HospitalCapital Medical UniversityBeijing 100050China Department of Neurology Affiliated Hospital of Changchun University of Chinese MedicineChangchun 130021China Department of Neurology Xuanwu HospitalCapital Medical UniversityBeijing 100053Chin Department of Neurology Beijing University of Chinese Medicine Third Affiliated HospitalBeijing 100029China Department of Geriatrics Jilin Academy of Traditional Chinese MedicineChangchun 130012China Department of Neurology Shenzhen Hospital of Beijing University of Chinese MedicineShenzhen 518172China Institute of Basic Research in Clinical Medicine China Academy Of Chinese Medical SciencesBeijing 100700Chin Department of Rehabilitation Shunyi HospitalBeijing Traditional Chinese Medicine HospitalBeijng 101300China Department of Neurology Xiyuan Hospital of China Academy of Chinese Medical SciencesBeijing 100091China

OBJECTIVE:To summarize the evidence from Traditional Chinese Medicine(TCM)practice in the treatment of acute primary headache and provide clinical practice ***:The guidelines were developed in accordance with the World Health Organization guideline development *** the establishment of steering committee,panel and the registration and protocol formulation,the evidence on TCM for acute primary headache from published guidelines,clinical evidence,and expert experience and consensus were *** grading of recommendations assessment,development and evaluation method was used to grade the evidence and make the ***:Based on the available evidence,the guidelines recommended three TCM herbal decoctions,six Chinese patent medicines,and two kinds of external application of Chinese herbal *** recommendations based on the expert experience and consensus were also included in the ***:TCM diagnosis and treatment of decoction,Chinese patent medicine and external application for treating acute primary headache were *** hope these guidelines will be helpful in standardize the TCM acute treatment of primary headache.

关键词： medicine,Chinese traditional acute primary headache practice guideline

Key Physical Factors Affecting Spatial-temporal Variation of Labile Organic Carbon Fractions by Biochar Driven in Mollisols Region of Northeast China

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Journal of Northeast Agricultural University(English Edition) 2024年第1期31卷 28-41页

作者： Zhao wei Liang fangyuan Liang Ying Zhao Hongrui Hao Shuai Wang Hongyan Wang Daqing College of Resources and Environment Northeast Agricultural UniversityHarbin 150030China Ulanqab Science and Technology Development Center Ulanqab 012000XinjiangChina Heilongjiang Agricultural Reclamation Economic Research Institute Harbin 150090China

Biochar is widely used to improve soil physical properties and carbon sequestration. However, few studies focuse on the impact of maize stalk biochar on labile organic carbon(LOC) pool and the relationship between physical properties and LOC fractions. A field positioning experiment was performed in Mollisols region of Northeast China to evaluate the influence of maize stalk biochar on the spatial distribution and temporal changes of physical properties and LOC fractions. Maize stalk biochar treatments included C1(1.5 kg·hm^(-2)), C2(3 kg·hm^(-2)), C3(15 kg·hm^(-2)), C4(30 kg·hm^(-2)), and CK(0). The results showed that maize stalk biochar increased soil water contents(SWC) and soil porosity(SP), but reduced bulk density(BD). Maize stalk biochar reduced dissolved organic carbon(DOC) contents in the 0-20 cm soil layer, ranging from 0.25 g·kg^(-1) to 0.31 g·kg^(-1) in harvest period, while increased in the 20-40 cm soil layer. In addition, the application of biochar had a significant impact on the spatial distribution and temporal change of SWC, BD, SP, DOC, hot-water extractable carbon(HWC), acid hydrolyzed organic carbon(AHC Ⅰ, Ⅱ), and readily oxidized organic carbon(ROC). High amounts of maize stalk biochar up-regulated the contents of soil organic carbon SOC, HWC, AHC Ⅰ, AHC Ⅱ, and ROC. In addition, SWC and SP were the key physical factors to affect LOC fractions. In conclusions, maize stalk biochar could improve physical properties, and then influence LOC fractions, and maize stalk biochar could be used as an organic amendment for restoring degraded soils governed by their rates of addition.

关键词： maize stalk biochar labile organic carbon fraction Mollisols region soil physical property dissolved organic carbon