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全民阅读与出版业的耦合关系研究

北京印刷学院学报 2024年第7期32卷 14-19页

作者：杨方铭淮阴工学院商学院淮安223001

全民阅读推广为出版业高质量发展提供重要机遇与利好背景,二者耦合有利于提升社会文明程度和精神共同富裕程度。本研究在构建全民阅读与出版业评价指标体系的基础上,利用熵值法和多系统耦合协调度模型计算权重、耦合度和耦合协调度。结... 详细信息

全民阅读推广为出版业高质量发展提供重要机遇与利好背景,二者耦合有利于提升社会文明程度和精神共同富裕程度。本研究在构建全民阅读与出版业评价指标体系的基础上,利用熵值法和多系统耦合协调度模型计算权重、耦合度和耦合协调度。结果表明2012—2021年,全民阅读综合发展水平呈快速上升态势,与之相比,出版业综合发展水平较低;两者耦合度处于磨合阶段,出版业能够有效支撑与推动全民阅读发展,并且彼此能够接纳和吸收各自发展带来的积极作用;两者耦合协调度相对较低,但是呈现稳健上升趋势。

关键词：全民阅读出版业测度指标体系耦合关系

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马泰壕煤矿煤流智能控制研究及应用

煤矿机电 2024年第2期45卷 55-59页

作者：杨访明永煤集团马泰壕煤矿内蒙古鄂尔多斯017200

为了解决煤矿井下无缓冲煤仓,煤流不均衡,带式输送机时而空载时而过载甚至压死带式输送机现象,利用AI技术对煤量进行识别,建立模型,对带式输送机进行智能调速,实现煤多快运煤少慢运,从而实现煤流均衡控制,杜绝了电能浪费和带式输送机过... 详细信息

为了解决煤矿井下无缓冲煤仓,煤流不均衡,带式输送机时而空载时而过载甚至压死带式输送机现象,利用AI技术对煤量进行识别,建立模型,对带式输送机进行智能调速,实现煤多快运煤少慢运,从而实现煤流均衡控制,杜绝了电能浪费和带式输送机过载情况。同时利用AI技术对煤流上异物进行识别,杜绝异物损伤输送带的情况。通过对煤流智能控制的研究,达到了煤流均衡生产、节能降耗、降低设备故障等效果。该控制系统在矿井煤流系统上具有推广意义。

关键词：煤流系统智能调速智能控制均衡生产智能化 AI

基于生鲜电商的产品因素对消费者满意度影响研究

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北京财贸职业学院学报 2024年第2期40卷 11-15页

作者：杨方铭淮阴工学院商学院江苏淮安223001

产品是影响消费者满意度的重要因素。本研究从产品整体概念出发,将产品因素划分为产品质量、功能服务、物流配送和产品价格四个子因素,再利用结构方程模型探究产品因素和消费者满意度之间的关系。结果表明:(1)产品因素对消费者满意度有... 详细信息

产品是影响消费者满意度的重要因素。本研究从产品整体概念出发,将产品因素划分为产品质量、功能服务、物流配送和产品价格四个子因素,再利用结构方程模型探究产品因素和消费者满意度之间的关系。结果表明:(1)产品因素对消费者满意度有显著影响,并呈现正比关系;(2)物流配送、产品质量、产品价格对消费者满意度有显著影响,而功能服务影响不显著,说明消费者购买生鲜产品的快速决策行为向需要思考的理性决策行为转变;(3)产品的四个因素均对期望满意度有显著影响,物流配送和产品质量对总体满意度有显著影响,而产品价格和功能服务对它的影响不显著,说明生鲜电商“价格战”过后,物流配送和产品质量是消费者真正关注的内容。基于研究结果提出了增加生鲜产品销售和提升消费者满意度的应对措施。

关键词：生鲜产品产品因素满意度

Multifunctional Sodium Gluconate Electrolyte Additive Enabling Highly Reversible Zn Anodes

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Chemical Research in Chinese Universities 2024年第4期40卷 722-729页

作者： ZHAO Kang ZHAO Jianan YU Meng LIU fangming DONG yang WANG Shiwen CHENG Fangyi College of Chemistry Nankai UniversityTianjin300071P.R.China College of New Energy Zhengzhou University of Light IndustryZhengzhou450002P.R.China

Sodium gluconate(SG)is reported as an electrolyte additive for rechargeable aqueous zinc *** SG addition is proposed to modulate the nucleation overpotential and plating behaviors of Zn by forming a shielding buffer layer because of the adsorption priority and large steric hindrance effect,which contributes to limited rampant Zn^(2+)diffusion and mitigated hydrogen evolution and *** the introduction of 30 mmol/L SG in 2 mol/L ZnSO_(4)electrolyte,the Zn anode harvests a reversible cycling of 1200 h at 5 mA/cm^(2)and a high average Coulombic efficiency of Zn plating/stripping(99.6%).Full cells coupling Zn anode with V_(2)O_(5)·1.6H_(2)O or polyaniline cathode far surpass the SG additivefree batteries in terms of cycle stability and rate *** work provides an inspiration for design of a high-effective and low-cost electrolyte additive towards Zn-based energy storage devices.

关键词： Electrolyte additive Zn anode Sodium gluconate Adsorption Zn dendrite

Photocatalyzed ditrifluoromethylthiolation of alkenes with CF_(3)SO_(2)Na

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Science China Chemistry 2024年第2期67卷 587-594页

作者： fangming Chen Lvqi Jiang Chunyang Hu Jie Liu Wenbin Yi School of Chemistry and Chemical Engineering Nanjing University of Science and TechnologyNanjing210094China Key Laboratory of Organofluorine Chemistry Shanghai Institute Organic ChemistryChinese Academy of SciencesShanghai200032China

Since the first report of sodium trifluoromethanesulfinate(CF_(3)SO_(2)Na) as an electrophilic trifluoromethylthiolation reagent in 2015,there has been no breakthrough in research in this ***,we disclose an unprecedented usage of CF_(3)SO_(2)Na as a radical trifluoromethylthiolation reagent.A photocatalyzed ditrifluoromethylthiolation of alkenes with CF_(3)SO_(2)Na in the presence of PPh_(3) and catalytic copper has been ***,either Ir[(p-Fppy)_(2)(bpy)]PF_6 or Ir(ppy)_(3) could facilitate this *** studies indicate that initiation of the radical chain proceeded via two different photocatalytic quenching *** protocol provides a practical method for the construction of diverse vicinal ditrifluoromethylthiolated compounds.

关键词： trifluoromethylthiolation photocatalysis radical difunctionalization alkenes

Plasma proteome profiling reveals biomarkers of chemotherapy resistance in patients with advanced colorectal cancer

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Quantitative Biology 2024年第2期12卷 215-224页

作者： Jingxin yang Jin Chen Luobin Zhang fangming Zhou Xiaozhen Cui Ruijun Tian Ruilian Xu Medical Genetic Center Affiliated Shenzhen Maternity and Child Healthcare HospitalSouthern Medical UniversityShenzhenChina Clinical Center for Molecular Diagnosis and Therapy The Second Affiliated Hospital of Fujian Medical UniversityQuanzhouChina Department of Chemistry and Research Center for Chemical Biology and Omics Analysis School of ScienceSouthern University of Science and TechnologyShenzhenChina Department of Oncology Shenzhen People’s Hospital(The Second Clinical Medical CollegeJinan UniversityThe First Affiliated HospitalSouthern University of Science and Technology)ShenzhenChina

Colorectal cancer(CRC)is one of the most common *** with advanced CRC can only rely on chemotherapy to improve ***,primary drug resistance frequently occurs and is difficult to *** in plasma protein composition have shown potential in clinical ***,it is urgent to identify potential protein biomarkers for primary resistance to chemotherapy for patients with *** sample preparation and high-throughput analysis were used to explore potential plasma protein *** susceptibility testing of circulating tumor cells(CTCs)has been investigated,and the relationship between their values and protein expressions has been *** addition,the differential proteins in different chemotherapy outcomes have been ***,the potential biomarkers have been detected via enzyme-linked immunosorbent assay(ELISA).Plasma proteome of 60 CRC patients were *** correlation between plasma protein levels and the results of drug susceptibility testing of CTCs was performed,and 85 proteins showed a significant positive or negative correlation with chemotherapy ***-four CRC patients were then divided into three groups according to their chemotherapy outcomes(objective response,stable disease,and progressive disease),and 37 differential proteins were found to be related to chemotherapy *** overlapping proteins were further investigated in an additional group of 79 patients using *** levels of F5 and PROZ significantly increased in the progressive disease group compared to other outcome *** study indicated that F5 and PROZ proteins could represent potential biomarkers of resistance to chemotherapy in advanced CRC patients.

关键词： biomarker chemotherapy resistance colorectal cancer plasma proteome

Genetic analysis and molecular mapping of a novel gene for zebra mutation in rice (Oryza sativa L.)

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Journal of Genetics and Genomics 2009年第11期36卷 679-684页

作者： Qiushi Wang,Xianchun Sang,Yinghua Ling,fangming Zhao,Zhenglin yang,Yunfeng Li,Guanghua He Key Laboratory of Biotechnology and Crop Quality Improvement,Ministry of Agriculture Rice Research Institute,Southwest University,Chongqing 400716,China Key Laboratory of Biotechnology and Crop Quality Improvement Ministry of Agriculture Rice Research Institute Southwest University Chongqing 400716 China

A novel zebra mutant, zebra-15, derived from the restorer line JinhuilO （Oryza sativa L. ssp. indica） treated by EMS, displayed a distinctive zebra leaf from seedling stage to jointing stage. Its chlorophyll content decreased （55.4%） and the ratio of Chla/Chlb increased （90.2%） significantly in the yellow part of the zebra-15, compared with the wild type. Net photosynthetic rate and fluorescence kinetic parameters showed that the decrease of chlorophyll content significantly influenced the photosynthetic efficiency of the mutant. Genetic analysis of F2 segregation populations derived from the cross of XinonglA and zebra-15 indicated that the zebra leaf trait is controlled by a single recessive nuclear gene. Ninety-eight out of four hundred and eighty pairs of SSR markers showed the diversity between the XinonglA and the zebra-15, their F2 population was then used for gene mapping. Zebra-15 （Z-15） gene was primarily restricted on the short arm of chromosome 5 by 150 F2 recessive individuals, 19.6 cM from marker RM3322 and 6.0 cM from marker RM6082. Thirty-six SSR markers were newly designed in the restricted location, and the Z-15 was finally located between markers nSSR516 and nSSR502 with the physical region 258 kb by using 1,054 F2 recessive individuals.

关键词： molecular mapping rice (Oryza sativa L.) zebra mutant chlorophyll Zebra-15

肝癌TACE术后复发危险因素的Meta分析

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胃肠病学和肝病学杂志 2024年第8期33卷 1027-1032页

作者：石丹丹陈晓琦杨芳明赵晴张晓彤裴蓉蓉朱帅帅陈欣菊河南中医药大学河南郑州450000 河南中医药大学第一附属医院消化内科

目的系统评价肝癌经动脉化疗栓塞术(transcatheter arterial chemoembolization, TACE)后影响复发的危险因素,为预防TACE术后复发提供科学依据。方法检索PubMed、EmBase、Cochrane Library、Web of Science、中国知网、万方数据库、... 详细信息

目的系统评价肝癌经动脉化疗栓塞术(transcatheter arterial chemoembolization, TACE)后影响复发的危险因素,为预防TACE术后复发提供科学依据。方法检索PubMed、EmBase、Cochrane Library、Web of Science、中国知网、万方数据库、维普、中国生物医学文献数据库自建库至2023年2月1日发表的有关肝癌TACE术后复发危险因素的文献报道。由2名研究者根据纳入和排除标准进行文献筛选、数据提取和质量评价。使用软件Rev Man 5.3对纳入文献进行Meta分析和发表偏倚评估。结果通过筛选最终共纳入9篇高质量队列研究进行Meta分析。分析结果显示差异有统计学意义的危险因素包括甲胎蛋白(OR=3.05,95%CI:1.11~8.38,P=0.03)、白蛋白(OR=5.79,95%CI:2.46~13.62,P<0.0001)、肿瘤分化程度(OR=2.64,95%CI:1.00~6.92,P=0.05)、肿瘤数量(OR=3.76,95%CI:1.71~8.27,P=0.001)、肿瘤ADC值(OR=0.01,95%CI:0.00~0.09,P<0.0001)。结论肿瘤直径、甲胎蛋白、白蛋白、肿瘤分化程度、肿瘤数量和肿瘤ADC值是TACE术后复发的危险因素。

关键词：肝癌经动脉化疗栓塞危险因素 Meta分析

Over 50,000 Metagenomically Assembled Draft Genomes for the Human Oral Microbiome Reveal New Taxa

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Genomics, Proteomics & Bioinformatics 2022年第2期20卷 246-259页

作者： Jie Zhu Liu Tian Peishan Chen Mo Han Liju Song Xin Tong Xiaohuan Sun fangming yang Zhipeng Lin Xing Liu Chuan Liu Xiaohan Wang Yuxiang Lin Kaiye Cai Yong Hou Xun Xu Huanming yang Jian Wang Karsten Kristiansen Liang Xiao Tao Zhang Huijue Jia Zhuye Jie BGI-Shenzhen Shenzhen 518083China Shenzhen Key Laboratory of Human Commensal Microorganisms and Health Research BGI-ShenzhenShenzhen 518083China Shenzhen Engineering Laboratory of Detection and Intervention of Human Intestinal Microbiome BGI-ShenzhenShenzhen 518083China Laboratory of Genomics and Molecular Biomedicine Department of BiologyUniversity of CopenhagenCopenhagen DK-2100Denmark James D.Watson Institute of Genome Sciences Hangzhou 310058China BGI-Qingdao BGI-ShenzhenQingdao 266555China

The oral cavity of each person is home to hundreds of bacterial *** taxa for oral diseases have been studied using culture-based characterization as well as amplicon sequencing,metagenomic and genomic information remains scarce compared to the fecal ***,using metagenomic shotgun data for 3346 oral metagenomic samples together with 808 published samples,we obtain 56,213 metagenome-assembled genomes(MAGs),and more than 64%of the 3589 species-level genome bins(SGBs)contain no publicly available *** resulting genome collection is representative of samples around the world and contains many genomes from candidate phyla radiation(CPR)that lack ***,it enables the discovery of new taxa such as a genus Candidatus Bgiplasma within the family ***-scale metagenomic data from massive samples also allow the assembly of strains from important oral taxa such as Porphyromonas and *** oral microbes encode genes that could potentially metabolize *** from these findings,a strongly male-enriched Campylobacter species was *** samples would be more user-friendly collected than fecal samples and have the potential for disease ***,these data lay down a genomic framework for future inquiries of the human oral microbiome.

关键词： Metagenomics Human oral microbiome Metagenome-assembly genome Genome catalog Gender