检索结果-南通市图书馆

ARNI联合EECP在PCI术后应用价值及对无创血流动力学指标再住院率的影响

在线全文

学校读者我要写书评

暂无评论

河北医学 2024年第7期30卷 1185-1191页

作者：王方明王翔亓华新山东第一医科大学附属人民医院心内科山东济南271199

目的:探讨血管紧张素受体脑啡肽酶抑制剂(ARNI)联合增强型体外反搏(EECP)在经皮冠状动脉介入(PCI)治疗术后价值以及对无创血流动力学指标、再住院率的影响。方法:选取2022年10月至2024年3月于山东第一医科大学附属人民医院心血管内科就... 详细信息

目的:探讨血管紧张素受体脑啡肽酶抑制剂(ARNI)联合增强型体外反搏(EECP)在经皮冠状动脉介入(PCI)治疗术后价值以及对无创血流动力学指标、再住院率的影响。方法:选取2022年10月至2024年3月于山东第一医科大学附属人民医院心血管内科就诊的急性前壁心肌梗死并成功行急诊PCI治疗术后患者100例为研究对象,随机分为试验组和对照组,每组50例,试验组采用ARNI联合EECP进行治疗,对照组采用血管紧张素转化酶抑制剂(ACEI)进行治疗,比较两组的心功能指标、生活质量量表(SF-36)以及血流动力学指标和再住院率。结果:治疗前,两组患者的心功能指标以及血流动力学指均无统计学差异(P>0.05),治疗7周后,两组患者的LVEDV、LVESV、NT-proBNP、ET-1、心率、SBP、DBP以及RS、CMR均降低,LVEF、CO、CI以及LSI、LCI、AC、COM均升高,较治疗前比较,均有统计学差异(P0.05),治疗7周后,上述评分均上升,较治疗前比较,均有统计学差异(P<0.05),且试验组改变幅度大于对照组,两组上述指标比较也有统计学差异(P<0.05);治疗后6个月随访,上述指标继续上升,但改变幅度变小,两组上述指标比较仍具有统计学差异(P<0.05);两组患者治疗后6个月总主要不良心血管事件导致再住院率两组比较具有统计学差异(χ^(2)=9.502,P=0.002);再发心肌梗死、心绞痛发作导致再住院率比较,无统计学差异(χ^(2)=0.340,P=0.560;χ^(2)=2.152,P=0.142),心力衰竭导致再住院率比较,差异有统计学意义(χ^(2)=6.353,P=0.012)。结论:ARNI联合EECP在PCI术后可以改善心功能以及患者健康状态,降低阻力,降低术后不良反应发生率,从而降低再住院率。

关键词：冠状动脉介入沙库巴缬沙坦增强型体外反搏应用价值血流动力学再住院率

Design and performance of an air inflatable suit in enhancing personal thermal management

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

中国科学:技术科学英文版 2023年第9期66卷 2637-2650页

作者： HE JiaZhen LU YeHu SU WenZhen wang fangming SONG WenFang wang LaiLi wang Min College of Textile and Clothing Engineering Soochow UniversitySuzhou 215021China Key Laboratory of Clothing Design and Technology Ministry of EducationDonghua UniversityShanghai 200051China Nantong Textile and Silk Industrial Technology Research Institute Nantong 226300China Suzhou Xingfengqiang Textile Technology Co. Ltd.Suzhou 215227China Garment Digital Engineering Center School of Art and DesignGuangdong University of TechnologyGuangzhou 510000China School of Fashion Design&Engineering Zhejiang Sci-Tech UniversityHangzhou 310018China

Maintaining human thermal comfort in cold indoor environments is crucial but usually involves excessive energy consumption and massive greenhouse gas emissions. Thermoregulating the human body by using advanced clothing is emerging as a promising solution to effectively and energy-efficiently achieve personal thermal management. An air inflatable suit(AirST)using a series of air chambers as the thermal insert was developed for the purpose of adjusting clothing thermal insulation and hence improving personal thermal comfort. The thermal insulation regulating performance of AirST was investigated through thermal manikin tests and wear trials. Compared with the AirST without air inflation, AirST after inflation with air had a desired effect, which could not only increase local clothing thermal insulation by a range from 4.5% to 24.8% but also alleviate cold strain and provide significantly higher local skin temperatures, mean skin temperature and mean body temperature. After inflation, AirST successfully improved the whole-, upper-and lower-body thermal sensations in a cool environment. The acceptable heating setpoint temperature by the air conditioner could be decreased while using AirST with inflation, which saved approximately 30% of building energy consumption. As the AirST without air inflation can also be worn as regular windproof clothing, this versatility saved approximately 12 kg CO_(2)e emissions in the production process.

关键词： air inflatable suit thermal comfort thermal insulation thermal management energy saving perceptual response

在线全文

学校读者我要写书评

暂无评论

高性能系列可溶桥塞的研制与应用

石油机械 2024年第1期52卷 124-129页

作者：张勇张国田刘宇王方明陈省身赵贺谦北京石油机械有限公司中国石油集团工程技术研究院有限公司

为提升可溶桥塞的工况适用性和稳定性,研发了多水解高分子基团可溶橡胶与高强度可溶金属材料及配方体系。通过开展不同温度下材料力学性能与溶解性能测试评价,验证了材料性能。根据可溶桥塞的结构原理及特点,研制了高性能系列可溶桥塞,... 详细信息

为提升可溶桥塞的工况适用性和稳定性,研发了多水解高分子基团可溶橡胶与高强度可溶金属材料及配方体系。通过开展不同温度下材料力学性能与溶解性能测试评价,验证了材料性能。根据可溶桥塞的结构原理及特点,研制了高性能系列可溶桥塞,进行了综合性能试验和现场试验。试验结果表明:研制桥塞能够在30~150℃温度范围内确保70 MPa有效承压密封时间达24 h以上,且溶解时间可调可控。各大油气田区块现场试验及推广应用结果表明,其坐封、承压、溶解效果等综合性能稳定可靠,能够适用于复杂工况,能有效保障体积压裂施工作业。所得结论可为非常规油气资源的高效开发及水平井分段压裂的提质降本提供有力的技术支撑。

关键词：可溶桥塞结构设计分段压裂承压密封溶解性能

Dynamic changes in fibrinogen levels of patients with acute cerebral infarction after taking defibrase

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2008年第5期3卷 513-516页

作者： Yi Guo Ling wang Bingshan Tang fangming Li Qizhang wang Department of Neurology the Second Affiliated Hospital of Jinan University Shenzhen 518020 Guangdong Province China

BACKGROUND： At present, as a therapeutic drug mainly for reducing fibrinogen （FIB） levels, the dynamic influence of defibrase on the FIB levels of patients with acute cerebral infarction has not been clearly ascertained. OBJECTIVE： To observe the dynamic changes in FIB levels of patients with acute cerebral infarction at different time points after taking defibrase. DESIGN, TIME AND SETTING： Randomized controlled clinical trial. The study was conducted in the Department of Neurology, the Second Affiliated Hospital of Jinan University, from June to November 2006. PARTICIPANTS： Sixty patients with acute cerebral infarction, who had been treated by the Neurological Department of the Second Affiliated Hospital of Jinan University from June to November 2006, were selected, including 37 males and 23 females, aged 35-75 years. All cases met the diagnostic criteria formulated by the Fourth National Cerebrovascular Disease Conference within 12 hours of onset. All the patients were confirmed with definite hemiparesis and cerebral infarction without coma, and were randomly divided into two groups： a treatment group （n =40） and a control group （n =20）. Patients＇ families had the right to be informed and agree with the treatment, which had permission from the Hospital Ethics Committee. METHODS： Patients in the control group were given routine treatment with 30 mL fleabane and 0.75 g cytidine diphosphate added to 500 mL saline solution once a day for 14 consecutive days. Patients in the treatment group were given routine treatment and Haiwang defibrase injection （purchased from Changchu Guoao Bio-Pharmaceutical Co. Ltd., Approval document number H10983237） within 12 hours of infarction. Defibrase doses of 15, 12.5 and 10 U were given over 2 hours according to the patients＇ pre-treatment plasma FIB levels of ≥ 4.50 g/L, 3.50 4.49 g/L and 1.00 3.49 g/L, respectively. Plasma FIB levels in the treatment group were measured before, and once every six hours for 48 hours after administr

关键词： cerebral infarction fibrinogen defibrase

在线全文

学校读者我要写书评

暂无评论

充气调温服装研究进展及发展趋势

纺织高校基础科学学报 2024年第4期37卷 55-61页

作者：项舒琪卢业虎孟晶王方明苏州大学纺织与服装工程学院江苏苏州215006 苏州大学现代丝绸国家工程实验室江苏苏州215006 苏州市兴丰强纺织科技有限公司江苏苏州215227

充气调温服装利用气囊锁闭静止空气,从而替代传统隔热层的填充材料,具有绿色环保、自由调温、轻量便携等特点,在防寒服领域极具应用价值。该文介绍了国内外充气调温服装的产品与专利技术,分析了充气调温服装的调温机理,总结了目前国内... 详细信息

充气调温服装利用气囊锁闭静止空气,从而替代传统隔热层的填充材料,具有绿色环保、自由调温、轻量便携等特点,在防寒服领域极具应用价值。该文介绍了国内外充气调温服装的产品与专利技术,分析了充气调温服装的调温机理,总结了目前国内外学者对充气调温服装保暖性影响因素的研究现状,并提出充气调温服装的不足与未来发展趋势。

关键词：充气调温服装保暖性调温机理黏合技术

SiC含量对SiC_(p)/2009Al复合材料微观组织及力学性能的影响

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

金属热处理 2024年第6期49卷 190-197页

作者：肖治同王方明颜泽华张勇曹振呼怀刚李炯利王旭东北京石墨烯技术研究院有限公司北京100094 北京石油机械有限公司北京102206 哈尔滨理工大学荣成学院山东威海264300 中国航发北京航空材料研究院北京100095 油气钻完井技术国家工程研究中心北京102206

通过在2009Al合金中引入不同质量分数(0、1%、3%、5%)的SiC颗粒,采用热等静压工艺制备了SiC_(p)/2009Al复合材料,随后进行了热挤压和固溶时效处理,研究了工艺过程对该复合材料组织与性能的影响。结果表明,采用热等静压工艺能够制备出晶... 详细信息

通过在2009Al合金中引入不同质量分数(0、1%、3%、5%)的SiC颗粒,采用热等静压工艺制备了SiC_(p)/2009Al复合材料,随后进行了热挤压和固溶时效处理,研究了工艺过程对该复合材料组织与性能的影响。结果表明,采用热等静压工艺能够制备出晶粒均匀且SiC分散均匀的复合材料,SiC颗粒与Al基体界面结合良好;经挤压工艺后,复合材料的微观组织明显改变,增强体SiC颗粒破碎并细化,当SiC含量较低(≤3%)时SiC颗粒沿挤压流均匀分布在基体中,SiC较高(>3%)时,SiC颗粒存在轻微的团聚现象。经固溶时效处理后,基体晶粒尺寸的均匀性提高,析出的第二相细小均匀弥散分布在基体中。通过对SiC_(p)/2009Al复合材料进行热挤压及固溶时效处理可以得到较优的综合力学性能。当引入质量分数为3%的SiC时,复合材料的力学性能更佳,其抗拉强度为492.7 MPa,屈服强度为400.9 MPa,断后伸长率为12.7%,硬度为131 HBW,在室温下兼具较好的耐磨性能。

关键词： SiC_(p)/2009Al复合材料热等静压力学性能耐磨性能

自噬调控小胶质细胞极化在缺血性脑卒中的研究进展

在线全文

学校读者我要写书评

暂无评论

实用医学杂志 2024年第9期40卷 1324-1330页

作者：王方明尚文璇张靖雯吉盈肖李俐涛河北医科大学研究生院石家庄050017 河北北方学院研究生院河北张家口075000 河北省人民医院神经内科(河北省脑网络与认知障碍疾病重点实验室) 石家庄050051

缺血性脑卒中具有发病率高、致残率高、病死率高的特点。炎症在缺血性脑卒中的发生发展中起到重要作用。活化的小胶质细胞表现出促炎(M1)和抗炎(M2)两个不同的表型,调节小胶质细胞由M1向M2型转化是临床获益关键。研究表明自噬对小胶质... 详细信息

缺血性脑卒中具有发病率高、致残率高、病死率高的特点。炎症在缺血性脑卒中的发生发展中起到重要作用。活化的小胶质细胞表现出促炎(M1)和抗炎(M2)两个不同的表型,调节小胶质细胞由M1向M2型转化是临床获益关键。研究表明自噬对小胶质细胞的表型转化起到关键调控作用。如何发挥自噬的调节作用,促进小胶质细胞向M2型转化,成为减轻脑卒中后继发性脑损伤的临床研究热点,本文以此为出发点综述自噬调控小胶质细胞极化在缺血性脑卒中的研究进展,旨在为本领域基础及临床研究提供参考。

关键词：缺血性脑卒中自噬小胶质细胞

Design of the rare-earth-containing materials based on the micro-alloying phase equilibria, phase diagrams and phase transformations

在线全文

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2023年第20期151卷 119-149页

作者： Kai Xu Chengcheng Zhan Ming Lou Xuelian Xiao Ruonan Zhou fangming wang Xiaofei Hu Yuan Yuan Keke Chang Key Laboratory of Marine Materials and Related Technologies Zhejiang Key Laboratory of Marine Materials and Protective TechnologiesNingbo Institute of Materials Technology and EngineeringChinese Academy of SciencesNingbo 315201China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China

Rare-earth(RE)elements,known as“industrial vitamins”,have permeated modern lives,especially in high-tech *** the RE elements possess close chemical similarities and have been treated as“one element”in the periodic table,their characteristics differ from each *** RE microalloying effect is the crux to ameliorate the physicomechanical and thermochemical properties of materials,thereby the study of RE-related phase diagrams becomes indispensable to the design and optimization of RE-containing ***,in reality,the knowledge base in this area is considerably scarce compared with that of other commonly-used *** this work,the phase equilibria,phase diagrams,phase transformations,and some recent examples of RE-containing materials design are summarized,with which one can predict the RE solubilities,the RE precipitates,as well as the corresponding service *** attainment of enhanced materials’properties suggests that the thermodynamic rules extracted from the phase diagrams could serve as fundamental criteria for the successful development of novel RE-containing materials.

关键词： Rare-earth elements Phase diagrams CALPHAD Phase transformations Materials design

Multifunctional Sodium Gluconate Electrolyte Additive Enabling Highly Reversible Zn Anodes

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2024年第4期40卷 722-729页

作者： ZHAO Kang ZHAO Jianan YU Meng LIU fangming DONG Yang wang Shiwen CHENG Fangyi College of Chemistry Nankai UniversityTianjin300071P.R.China College of New Energy Zhengzhou University of Light IndustryZhengzhou450002P.R.China

Sodium gluconate(SG)is reported as an electrolyte additive for rechargeable aqueous zinc *** SG addition is proposed to modulate the nucleation overpotential and plating behaviors of Zn by forming a shielding buffer layer because of the adsorption priority and large steric hindrance effect,which contributes to limited rampant Zn^(2+)diffusion and mitigated hydrogen evolution and *** the introduction of 30 mmol/L SG in 2 mol/L ZnSO_(4)electrolyte,the Zn anode harvests a reversible cycling of 1200 h at 5 mA/cm^(2)and a high average Coulombic efficiency of Zn plating/stripping(99.6%).Full cells coupling Zn anode with V_(2)O_(5)·1.6H_(2)O or polyaniline cathode far surpass the SG additivefree batteries in terms of cycle stability and rate *** work provides an inspiration for design of a high-effective and low-cost electrolyte additive towards Zn-based energy storage devices.

关键词： Electrolyte additive Zn anode Sodium gluconate Adsorption Zn dendrite