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Numerical study of growth competition between twin grains during directional solidification by using multi-phase field method

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Chinese Physics B 2022年第2期31卷 626-633页

作者： Chang-Sheng Zhu Ting Wang Li Feng Peng Lei fang-lan ma School of Computer and Communication Lanzhou University of TechnologyLanzhou 730050China State Key Laboratory of Gansu Advanced Processing and Recycling of Non-Ferrous Metal Lanzhou University of TechnologyLanzhou 730050China

A multi-phase field model is established to simulate the growth competition and evolution behavior between seaweed and columnar dendrites during directional *** to the effects of surface tension and interfacial energy,we quantitatively analyze the influences of factors such as inclination angles,pulling velocity,and anisotropic strength on twin *** results demonstrate that the pulling velocity and anisotropic strength have an important influence on the morphology and evolution of the seaweed and dendritic *** low pulling velocity and anisotropic strength are both key parameters for maintaining the stable morphology of seaweed during competitive growth in a bicrystal,showing that the lateral branching behavior is the root of the dendrites that can ultimately dominate the *** it is clarified that the lateral branching behavior and lateral blocking are the root causes of the final dominant growth of *** the increase of anisotropy strength,the seaweed is eliminated fastest in case 1,the seaweed is transformed into degenerate dendritic morphology,and eliminates the seaweed by promoting the generation and lateral growth of the lateral branches of the *** increase of pulling velocity is to increase the undercooling of favorable oriented grain and accelerate the growth rate of dendrites,thus producing more new primary dendrites for lateral expansion and accelerating the elimination rate of unfavorable oriented grain.

关键词： multi-phase field simulation grain growth competition directional solidification twin grains

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Three-dimensional multi-phase-field simulation of eutectoid alloy based on OpenCL parallel

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China Foundry 2021年第3期18卷 239-248页

作者： Chang-sheng Zhu Yu-jie Li fang-lan ma Li Feng Peng Lei School of Computer and Communication Lanzhou University of TechnologyLanzhou 730050China State Key Laboratory of Gansu Advanced Processing and Recycling of Non-Ferrous Metal Lanzhou University of TechnologyLanzhou 730050China School of materials Science and Engineering Lanzhou University of TechnologyLanzhou 730050China

Seeking high-performance computing methods to solve the problem of a large amount of calculation,low calculation efficiency,and small simulation scale on the traditional single central processing unit (CPU) platform is of great value to the simulation study of *** this study,based on the three-dimensional multi-phase-field model of KKSO coupling phase-field and solute field,the open computing language (OpenCL) + graphics processing unit (GPU) heterogeneous parallel computing technology is used to simulate the eutectoid growth of Fe-C alloy and the end growth process of pearlite under pure *** effects of initial supercooling and different diffusion coefficients on the growth morphology of lamellar pearlite were *** results show that ferrite and cementite are perpendicular to the front of the solid-solid interface and are coupled and coordinated to grow,and there is no leading phase under the initial supercooling degree of 20 *** the continuous increase of the initial supercooling degree (19 K-22 K),the morphology changes of the eutectoid layer are as follows:cementite stops growing → slice amplitude increases → regular symmetric growth → oblique growth → layer *** the increase of the diffusion coefficient from 3×10^(-13) m^(2)·s^(-1) to 15×10^(-13) m^(2)·s^(-1),the growth rate of the microstructure of the lamellar pearlite increases linearly,and there is no obvious change in the frontal appearance of the pearlite.

关键词： phase-field model lamellar pearlite eutectoid phase transition OpenCL Fe-C alloy

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Small extracellular vesicles derived from human induced pluripotent stem cell-differentiated neural progenitor cells mitigate retinal ganglion cell degeneration in a mouse model of optic nerve injury

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Neural Regeneration Research 2025年第2期20卷 587-597页

作者： Tong Li Hui-Min Xing Hai-Dong Qian Qiao Gao Sheng-lan Xu Hua ma Zai-Long Chi State Key Laboratory of Ophthalmology Optometry and Visual ScienceEye HospitalWenzhou Medical UniversityWenzhouZhejiang ProvinceChina National Clinical Research Center for Ocular Diseases Eye HospitalWenzhou Medical UniversityWenzhouZhejiang ProvinceChina

Several studies have found that transplantation of neural progenitor cells(NPCs)promotes the survival of injured ***,a poor integration rate and high risk of tumorigenicity after cell transplantation limits their clinical *** extracellular vesicles(sEVs)contain bioactive molecules for neuronal protection and *** studies have shown that stem/progenitor cell-derived sEVs can promote neuronal survival and recovery of neurological function in neurodegenerative eye diseases and other eye *** this study,we intravitreally transplanted sEVs derived from human induced pluripotent stem cells(hiPSCs)and hiPSCs-differentiated NPCs(hiPSC-NPC)in a mouse model of optic nerve *** results show that these intravitreally injected sEVs were ingested by retinal cells,especially those localized in the ganglion cell *** with hiPSC-NPC-derived sEVs mitigated optic nerve crush-induced retinal ganglion cell degeneration,and regulated the retinal microenvironment by inhibiting excessive activation of *** analysis further revealed that hiPSC-NPC derived sEVs transported neuroprotective and anti-inflammatory miRNA cargos to target cells,which had protective effects on RGCs after optic nerve *** findings suggest that sEVs derived from hiPSC-NPC are a promising cell-free therapeutic strategy for optic neuropathy.

关键词： exosome miRNA neural progenitor cell neurodegeneration neuroinflammation neuroprotection optic nerve crush optic neuropathy retinal ganglion cell small extracellular vesicles

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阿片类药物诱导瘙痒的机制研究进展

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中国药理学通报 2025年第1期41卷 29-34页

作者：马芳周培岚苏瑞斌军事医学研究院国家安全特需药品全国重点实验室北京100850 南京中医药大学药学院江苏南京210046

瘙痒是临床使用阿片类药物镇痛的患者普遍存在的严重不良反应之一。大量研究已经阐明阿片类药物的镇痛机制,但阿片类药物诱导瘙痒的机制尚不明确,瘙痒与镇痛之间的关系也模糊不清。目前的研究发现,阿片类药物作用于μ、κ及δ阿片受体后... 详细信息

瘙痒是临床使用阿片类药物镇痛的患者普遍存在的严重不良反应之一。大量研究已经阐明阿片类药物的镇痛机制,但阿片类药物诱导瘙痒的机制尚不明确,瘙痒与镇痛之间的关系也模糊不清。目前的研究发现,阿片类药物作用于μ、κ及δ阿片受体后,直接或间接影响瘙痒关键受体——胃泌素释放肽受体的功能,进而影响瘙痒信息传递。神经介素B、神经肽Y、B型利钠肽等神经肽,以及其他受体如瞬时受体电位香草素1受体、N-甲基-D-天冬氨酸受体、5-羟色胺受体等,在吗啡诱导的瘙痒中也具有重要作用。此外,阿片类药物所致瘙痒的预防和治疗也是围手术期吗啡镇痛的难点和热点之一。因此,明确瘙痒的具体发生机制,对寻找新的研究思路及预防和治疗阿片类药物诱导的瘙痒具有重要意义。

关键词：阿片类诱导的瘙痒瘙痒与镇痛瘙痒机制阿片受体胃泌素释放肽受体瘙痒治疗

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Nitrogen addition promotes soil carbon accumulation globally

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Science China Life Sciences 2025年第1期 284-293页

作者： Xuemei Yang Suhui ma Erhan Huang Danhua Zhang Guoping Chen Jiangling Zhu Chengjun Ji Biao Zhu Lingli Liu Jingyun fang Institute of Ecology College of Urban and Environmental Sciencesand Key Laboratory for Earth Surface Processes of the Ministry of EducationPeking University Ministry of Education Key Laboratory for Transboundary Ecosecurity of Southwest China School of Ecology and Environmental ScienceYunnan University State Key Laboratory of Vegetation and Environmental Change Institute of BotanyChinese Academy of Sciences

Soil is the largest carbon(C) reservoir in terrestrial ecosystems and plays a crucial role in regulating the global C cycle and climate *** nitrogen(N) deposition has been widely considered as a critical factor affecting soil organic carbon(SOC) storage, but its effect on SOC components with different stability remains unclear. Here, we analyzed extensive empirical data from 304 sites worldwide to investigate how SOC and its components respond to N addition. Our analysis showed that N addition led to a significant increase in bulk SOC(6.7%), with greater increases in croplands(10.6%) and forests(6.0%) compared to grasslands(2.1%). Regarding SOC components, N addition promoted the accumulation of plant-derived C(9.7%–28.5%) over microbial-derived C(0.2%), as well as labile(5.7%) over recalcitrant components(–1.2%), resulting in a shift towards increased accumulation of plant-derived labile C. Consistently, N addition led to a greater increase in particulate organic C(11.9%) than mineral-associated organic C(3.6%), suggesting that N addition promotes C accumulation across all pools, with more increase in unstable than stable pools. The responses of SOC and its components were best predicted by the N addition rate and net primary productivity. Overall, our findings suggest that N enrichment could promote the accumulation of plant-derived and non-mineral associated C and a subsequent decrease in the overall stability of soil C pool, which underscores the importance of considering the effects of N enrichment on SOC components for a better understanding of C dynamics in soils.

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Efficient and Stable Photoassisted Lithium-Ion Battery Enabled by Photocathode with Synergistically Boosted Carriers Dynamics

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NANO-MICRO LETTERS 2025年第1期17卷 1-15页

作者： ma, Zelin Wang, Shiyao ma, Zhuangzhuang Li, Juan Zhao, Luomeng Li, Zhihuan Wang, Shiyuan Shuang, Yazhou Wang, Jiulong Wang, fang Xia, Weiwei Jian, Jie He, Yibo Wang, Junjie Guo, Pengfei Wang, Hongqiang Northwestern Polytech Univ Ctr Nano Energy Mat State Key Lab Solidificat Proc Sch Mat Sci & Engn Xian 710072 Peoples R China NPU Shaanxi Joint Lab Graphene Xian 710072 Peoples R China Northwestern Polytech Univ Sch Mat Sci State Key Lab Solidificat Proc Xian 710072 Peoples R China Northwestern Polytech Univ Engn Dept Xian 710072 Peoples R China Northwestern Polytech Univ Ctr Adv Lubricat & Seal Mat Sch Mat Sci & Engn State Key Lab Solidificat Proc Xian 710072 Peoples R China Northwestern Polytech Univ Shenzhen Res & Dev Inst Shenzhen 518063 Peoples R China Shaanxi Normal Univ Key Lab Appl Surface & Colloid Chem Shaanxi Engn Lab Adv Energy Technol Shaanxi Key Lab Adv Energy DevicesSch Mat Sci & E Xian 710119 Peoples R China

Efficient and stable photocathodes with versatility are of significance in photoassisted lithium-ion batteries (PLIBs), while there is always a request on fast carrier transport in electrochemical active photocathodes. Present work proposes a general approach of creating bulk heterojunction to boost the carrier mobility of photocathodes by simply laser assisted embedding of plasmonic nanocrystals. When employed in PLIBs, it was found effective for synchronously enhanced photocharge separation and transport in light charging process. Additionally, experimental photon spectroscopy, finite difference time domain method simulation and theoretical analyses demonstrate that the improved carrier dynamics are driven by the plasmonic-induced hot electron injection from metal to TiO2, as well as the enhanced conductivity in TiO2 matrix due to the formation of oxygen vacancies after Schottky contact. Benefiting from these merits, several benchmark values in performance of TiO2-based photocathode applied in PLIBs are set, including the capacity of 276 mah g(-1 ) at 0.2 A g(-1 )under illumination, photoconversion efficiency of 1.276% at 3 A g(-1 ), less capacity and Columbic efficiency loss even through 200 cycles. These results exemplify the potential of the bulk heterojunction strategy in developing highly efficient and stable photoassisted energy storage systems.

关键词： Photoassisted lithium-ion batteries Bulk heterojunction Carrier dynamics TiO2 nanofiber Plasmonic metal nanocrystals

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Local magnetic moment oscillation around an Anderson impurity on graphene

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 192-201页

作者： Shuai Li Zhen ma Jin-Hua Gao School of Science Hebei University of Science and Technology School of Electronics and Information Zhengzhou University of Light Industry School of Physics and Wuhan National High magnetic Field Center Huazhong University of Science and Technology

We theoretically investigate the spin resolved Friedel oscillation （FO） and quasiparticle interference （QPI） in graphene induced by an Anderson *** the impurity becomes magnetic,the resulted FO becomes spin dependent,which gives rise to a local magnetic moment oscillation with an envelop decaying as r-2in real space in the doping ***,at half filling,the electron density and local magnetic moment will not oscillate but decay as *** spin resolved FO has both sublattice and spin ***,the local magnetic moment decay at half filling only occurs at one sublattice of graphene,which is quite like the phenomenon observed in the STM experiment (***ález-Herrero et al.,Science 352,437 （2016）).We further give an analytic formula about such spin dependent FO based on the stationary phase ***,we study the interference of quasiparticles around the magnetic impurity by calculating the spin dependent Fourier-transformed local density of states （FT-LDOS）.Our work gives a comprehensive understanding about the local magnetic moment oscillation around an Anderson impurity on graphene.

关键词： Friedel oscillation local magnetic moment graphene Anderson impurity

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恶劣综采工况条件下的采煤机摇臂散热设计研究

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煤矿机械 2025年第1期46卷 35-37页

作者：马兰上海创力集团股份有限公司上海201706

简述了在采煤机设计过程中对恶劣综采工况中工作倾角较大、煤岩硬度较硬、截割功率大且结构紧凑限制条件下的摇臂热功率的计算,分析了该工况中摇臂简化为复杂齿轮箱思路下的热功率计算、散热途径和热平衡点,提出了摇臂内部结构改进及增... 详细信息

简述了在采煤机设计过程中对恶劣综采工况中工作倾角较大、煤岩硬度较硬、截割功率大且结构紧凑限制条件下的摇臂热功率的计算,分析了该工况中摇臂简化为复杂齿轮箱思路下的热功率计算、散热途径和热平衡点,提出了摇臂内部结构改进及增加外置冷却装置的散热设计方案,并验证了满载试验条件下摇臂截割热平衡温度不超过90℃的方案可行性。

关键词：大功率大倾角采煤机摇臂紧凑结构热功率热平衡

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Harnessing therapeutic potential of induced pluripotent stem cell–derived endothelial cells for remyelination in the central nervous system

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Neural Regeneration Research 2025年第6期20卷 1715-1716页

作者： Dan ma Nona Pop Aston Medical School College of Health and Life SciencesAston UniversityBirminghamUK

Myelin is the protective sheath surrounding nerve fibers, and its damage(demyelination) occurs in many central nervous system(CNS) diseases, including multiple sclerosis(MS), traumatic injury, neurodegenerative diseases such as Alzheimer's disease, and mental disorders such as schizophrenia(Barateiro et al., 2016). Repair of damaged myelin sheaths(remyelination) often fails in MS, leading to neuronal loss and irreversible functional deficits.

关键词： myelin protective diseases

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Transient receptor potential channels and calcium dysregulation: a pathogenic duo in Parkinson's disease

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Neural Regeneration Research 2025年第3期20卷 808-810页

作者： Iqira Saeed Linlin ma Griffith Institute for Drug Discovery Griffith UniversityNathanBrisbaneQLDAustralia School of Environment and Science Griffith University NathanBrisbaneQLDAustralia

Parkinson's disease(PD) has a complex and multifactorial pathophysiology. Various studies, conducted both in pre-clinical models and PD patients, have reported a link between the disruption of calcium(Ca^(2+)) homeostasis and the subsequent development of PD. Ca^(2+) regulation is crucial for neuronal survival, differentiation,exocytosis at synapses,gene transcription,and proliferation.

关键词： homeostasis clinical subsequent

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